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$479+ Cheap flights from Missouri to Greenville, NC (PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PGV
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:40 pm
MCI
-
PGV
1 stop5h 18m
American Airlines
Sun 6/76:21 pm
PGV
-
MCI
1 stop6h 35m
American Airlines
Deal found 1/27$479
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:52 am
STL
-
PGV
1 stop4h 46m
American Airlines
Sun 2/155:05 am
PGV
-
STL
1 stop4h 30m
American Airlines
Deal found 1/27$546
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:57 pm
STL
-
PGV
1 stop14h 43m
American Airlines
Fri 3/206:03 pm
PGV
-
STL
1 stop15h 32m
American Airlines
Deal found 1/27$902

Find flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$479
(American Airlines)
Provider with most accurate pricing for Lambert-St Louis-Pitt-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Pitt-Greenville flights.
Search Deals
From Missouri to Pitt-Greenville
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Wed 6/3

5:40 pm-11:58 pm

1 stop5h 18m

Pitt-Greenville

Sun 6/7

6:21 pm-11:56 pm

1 stop6h 35m

$479

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Wed 2/11

6:52 am-12:38 pm

1 stop4h 46m

Pitt-Greenville

Sun 2/15

5:05 am-8:35 am

1 stop4h 30m

$546

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Fri 2/13

6:57 pm-11:47 pm

1 stop3h 50m

Pitt-Greenville

Tue 2/17

6:00 am-9:40 am

1 stop4h 40m

$546

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Fri 3/13

6:57 pm-10:40 am

1 stop14h 43m

Pitt-Greenville

Fri 3/20

6:03 pm-8:35 am

1 stop15h 32m

$902

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville, North Carolina?

Currently, April is the cheapest month in which you can book a flight from Missouri to Greenville, North Carolina (average of $108). Flying from Missouri to Greenville, North Carolina in February is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Greenville from Missouri?

    For a flight from Missouri to Greenville, you will be flying into Pitt-Greenville. Pitt-Greenville (PGV) is just 1.7 mi from the center of the city.

  • How long is the flight from Missouri to Greenville, North Carolina?

    For as low as $479, American Airlines can have you in Greenville, North Carolina from Missouri in 5h 18m. Missouri and Greenville, North Carolina are separated by a distance of 981 mi.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville, North Carolina?

    Currently, April is the cheapest month in which you can book a flight from Missouri to Greenville, North Carolina (average of $108). Flying from Missouri to Greenville, North Carolina in February is currently the most expensive (average of $206). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

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