Greenville

$354+ Cheap flights from Missouri to Greenville, NC (PGV)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PGV
Aug 25 — Sep 11
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Greenville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Greenville

Keep the following information in mind while searching for Missouri to Greenville flight deals. Data was last updated August 20, 2025.

Round-trip from

$234
(American Airlines)
From Missouri to Pitt-Greenville

Find flight deals from Missouri to Greenville

Cheapest flights from Missouri to Greenville
Explore the most affordable flight options available from Missouri to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 20, 2025.

This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:15 pmMCI - PGV
1 stop5h 11mAmerican Airlines
Sun 9/217:22 pmPGV - MCI
1 stop5h 43mAmerican Airlines
Deal found 8/19$354
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/26:30 pmMCI - PGV
1 stop4h 29mAmerican Airlines
Mon 10/63:09 pmPGV - MCI
2 stops8h 42mAmerican Airlines
Deal found 8/18$359
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/113:50 pmMCI - PGV
1 stop7h 09mAmerican Airlines
Mon 9/155:07 pmPGV - MCI
1 stop5h 19mAmerican Airlines
Deal found 8/18$384
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:25 amSTL - PGV
1 stop4h 36mAmerican Airlines
Sun 10/125:00 amPGV - STL
1 stop4h 16mAmerican Airlines
Deal found 8/20$400
This American Airlines deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/211:04 amMCI - PGV
1 stop6h 36mAmerican Airlines
Sat 9/65:07 pmPGV - MCI
1 stop5h 19mAmerican Airlines
Deal found 8/17$449
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/223:53 pmSTL - PGV
1 stop6h 08mAmerican Airlines
Mon 8/2512:11 pmPGV - STL
1 stop5h 45mAmerican Airlines
Deal found 8/19$529
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/31:14 pmMCI - PGV
2 stops9h 12mAmerican Airlines
Sun 9/76:00 amPGV - MCI
2 stops9h 13mAmerican Airlines
Deal found 8/19$548
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/244:32 pmSTL - PGV
1 stop6h 27mAmerican Airlines
Wed 8/276:00 amPGV - STL
1 stop4h 29mAmerican Airlines
Deal found 8/19$581
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1810:28 amMCI - PGV
2 stops7h 29mAmerican Airlines
Mon 9/226:00 amPGV - MCI
2 stops10h 52mAmerican Airlines
Deal found 8/18$587

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 20, 2025.
Use the filters below to find and compare flights from Missouri to Greenville that are best for you.

Fly from

Missouri

Fly to

Greenville

Route

Depart

Return

Price

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Fri 9/19

5:15 pm-11:26 pm

1 stop5h 11m

Pitt-Greenville

Sun 9/21

7:22 pm-12:05 am

1 stop5h 43m

$354

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Thu 10/2

6:30 pm-11:59 pm

1 stop4h 29m

Pitt-Greenville

Mon 10/6

3:09 pm-10:51 pm

2 stops8h 42m

$359

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Thu 9/11

3:50 pm-11:59 pm

1 stop7h 09m

Pitt-Greenville

Mon 9/15

5:07 pm-9:26 pm

1 stop5h 19m

$384

St. LouisGreenville

STL - PGV

STLPGV

Lambert-St Louis

Tue 10/7

6:25 am-12:01 pm

1 stop4h 36m

Pitt-Greenville

Sun 10/12

5:00 am-8:16 am

1 stop4h 16m

$400

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Tue 9/2

11:04 am-6:40 pm

1 stop6h 36m

Pitt-Greenville

Sat 9/6

5:07 pm-9:26 pm

1 stop5h 19m

$449

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Thu 9/18

3:50 pm-11:59 pm

1 stop7h 09m

Pitt-Greenville

Mon 9/22

5:07 pm-9:26 pm

1 stop5h 19m

$449

Kansas CityGreenville

MCI - PGV

MCIPGV

Kansas City

Wed 9/3

8:00 am-4:42 pm

1 stop7h 42m

Pitt-Greenville

Sun 9/7

7:22 pm-12:05 am

1 stop5h 43m

$449

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/17

Best time to book a flight from Missouri to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Greenville

What is the cheapest month to book a flight from Missouri to Greenville, North Carolina?

Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville, North Carolina (average of $302). Flying from Missouri to Greenville, North Carolina in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Greenville from Missouri?

    For a flight from Missouri to Greenville, you will be flying into Pitt-Greenville. Pitt-Greenville (PGV) is just 1.7 mi from the center of the city.

  • How long is the flight from Missouri to Greenville, North Carolina?

    For as low as $354, American Airlines can have you in Greenville, North Carolina from Missouri in 5h 11m. Missouri and Greenville, North Carolina are separated by a distance of 981 mi.

  • Can I find deals for flights from Missouri to Greenville that include hotel bookings?

    Yes. In addition to deals on Missouri to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Greenville.

  • Can I find deals for business class flights from Missouri to Greenville?

    Yes. Cheapflights offers flight deals from Missouri to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Greenville, North Carolina?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Greenville, North Carolina (average of $302). Flying from Missouri to Greenville, North Carolina in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Williamston

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Greenville

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.