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$109+ Cheap flights from Denver to Greenville (DEN - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — GSP
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Find cheap flights from Denver to Greenville with Cheapflights

1. Tell us where you want to go

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Cheapflights Tip: The best prices from Denver Intl to Greenville are usually found in February or June, booked 58 days in advance, depart on a Saturday or Thursday and return on a Friday

Cheap flight deals from Denver to Greenville

Cheapest flights from Denver to Greenville
Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:15 am
DEN
-
GSP
1 stop5h 55m
Southwest
Wed 4/291:55 pm
GSP
-
DEN
1 stop7h 15m
Southwest
Deal found 3/26$218
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:15 am
DEN
-
GSP
1 stop5h 55m
Southwest
Sat 4/188:00 am
GSP
-
DEN
1 stop9h 15m
Southwest
Deal found 3/24$239
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/147:50 am
DEN
-
GSP
1 stop6h 30m
Southwest
Wed 4/156:45 am
GSP
-
DEN
1 stop5h 30m
Southwest
Deal found 3/26$254
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/312:40 pm
DEN
-
GSP
2 stops7h 00m
Southwest
Sat 6/68:15 am
GSP
-
DEN
2 stops12h 10m
Southwest
Deal found 3/23$255
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:59 pm
DEN
-
GSP
1 stop12h 45m
Multiple Airlines
Mon 4/205:43 pm
GSP
-
DEN
2 stops25h 57m
Multiple Airlines
Deal found 3/25$257
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:15 am
DEN
-
GSP
1 stop5h 55m
Southwest
Fri 4/176:25 pm
GSP
-
DEN
1 stop7h 20m
Southwest
Deal found 3/25$259

Find flight deals from Denver to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$218
(Southwest)

One-way from

$109
(Southwest)

Popular in

November

Cheapest in

February

Average price

$451

Good round-trip deal

$380 or less

Good one-way deal

$300 or less
Provider with most accurate pricing for Denver Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Greenville flights.
Search Deals
From Denver Intl to Greenville
Search Deals
One-way flight from Denver Intl to Greenville
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Denver Intl to Greenville.
Search Deals
Price to beat on a one-way flight from Denver Intl to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Denver to Greenville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 6/5

12:40 pm-10:45 pm

2 stops8h 05m

Greenville

Mon 6/8

6:50 pm-11:35 pm

1 stop6h 45m

$286

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 5/5

12:40 pm-9:40 pm

2 stops7h 00m

Greenville

Sat 5/9

6:25 am-9:45 am

1 stop5h 20m

$334

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 8/20

1:35 pm-9:25 pm

1 stop5h 50m

Greenville

Thu 9/10

7:15 am-2:02 pm

1 stop8h 47m

$357

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 6/18

2:15 pm-11:59 pm

1 stop7h 44m

Greenville

Tue 7/7

3:35 pm-9:40 pm

1 stop8h 05m

$357

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Mon 4/6

5:05 am-11:45 am

1 stop4h 40m

Greenville

Fri 4/10

6:25 pm-11:45 pm

1 stop7h 20m

$389
Quickest round-trip

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Sat 5/23

10:13 am-3:19 pm

Nonstop3h 06m

Greenville

Sun 5/24

4:15 pm-5:55 pm

Nonstop3h 40m

$399

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 4/21

6:00 am-2:12 pm

1 stop6h 12m

Greenville

Wed 4/29

4:10 pm-6:00 pm

Nonstop3h 50m

$404

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 8/20

10:03 am-3:10 pm

Nonstop3h 07m

Greenville

Thu 9/10

7:51 pm-12:19 am

1 stop6h 28m

$409

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 6/23

6:13 am-2:20 pm

1 stop6h 07m

Greenville

Wed 7/1

4:15 pm-5:55 pm

Nonstop3h 40m

$409

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 6/18

2:15 pm-11:59 pm

1 stop7h 44m

Greenville

Sun 6/21

5:16 pm-9:57 pm

1 stop6h 41m

$418

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/26

Showing 1-10 of 22 resultsSorted by cheapest first
1
2
3

Compare providers for flights from Denver to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Greenville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Greenville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Greenville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Greenville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Greenville

How far ahead should I book a flight from Denver to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Greenville. Price data was last updated on March 13, 2026.

Booking 58 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Denver to Greenville?

Currently, January is the cheapest month in which you can book a flight from Denver to Greenville (average of $72). Flying from Denver to Greenville in November is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to GSP?

Find hourly flight availability from Denver to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 27, 2026.

When flying from Denver to Greenville, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Denver to Greenville?

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated March 27, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Denver to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,331 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,331 reviews
Southwest
8.0
Very good
4,331 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,341 reviews
Southwest
8.0
Very good
4,331 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
United Airlines
7.4
Good
9,491 reviews
Southwest
8.0
Very good
4,331 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,504 reviews
Southwest
8.0
Very good
4,331 reviews

Crew

8.6

Boarding

8.1

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Denver to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Denver to Greenville flight route?

    Within the past month, 2 users have taken a look at flights from Denver Intl to Greenville.

  • How long is the flight from Denver to Greenville?

    Southwest and Delta can get you from Denver to Greenville in just under 5h 50m. Your travel time can differ by up to 2h 15m. Airlines will cover a distance of 1275 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Denver to Greenville round-trip?

    Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $188. Additional round-trip tickets that might be worth considering are offered by Southwest and Delta, with the lowest prices starting at $231 and $236, respectively. These flights start at 52% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Denver to Greenville one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $134. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Denver to Greenville for a low price.

  • What are the cheapest flights from Denver to Greenville?

    While on average a flight from Denver to Greenville is generally $372, our data shows the cheapest flight currently is $253. When looking at the most popular route, (Denver Intl - Greenville), you can expect to pay $218 for that flight.

  • Can I find deals for flights from Denver to Greenville that include hotel bookings?

    Yes. In addition to deals on Denver to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Greenville.

  • Can I find deals for business class flights from Denver to Greenville?

    Yes. Cheapflights offers flight deals from Denver to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Greenville?

    Currently, January is the cheapest month in which you can book a flight from Denver to Greenville (average of $72). Flying from Denver to Greenville in November is currently the most expensive (average of $135). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Greer
Simpsonville
Duncan
Seneca
Anderson

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Top 4 airlines flying from Denver to Greenville

Discover the top 4 airlines that operate flights from Denver to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$188Average$371FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$231Average$403FlexibilityNo cancel feeOn-time63%
DeltaCheapest$236Average$305FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$249Average$460FlexibilityNo cancel feeOn-time69%

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