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$145+ Cheap flights from Denver to Greenville (DEN - GSP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — GSP
Dec 29 — Jan 51
Mon 12/29
Mon 1/5
1 adult, Economy
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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Denver Intl to Greenville are usually found in February or August, booked 82 days in advance, depart on a Tuesday or Friday and return on a Thursday

Find flight deals from Denver to Greenville

Cheapest flights from Denver to Greenville
Explore the most affordable flight options available from Denver to Greenville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 29, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:59 pmDEN - GSP
1 stop17h 24mMultiple Airlines
Thu 12/2511:33 amGSP - DEN
2 stops13h 03mMultiple Airlines
Deal found 11/29$278
This American Airlines deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:59 pmDEN - GSP
1 stop6h 37mAmerican Airlines
Fri 1/25:00 amGSP - DEN
1 stop6h 20mAmerican Airlines
Deal found 11/27$293
This Delta deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:44 pmDEN - GSP
1 stop4h 56mDelta
Mon 12/227:59 pmGSP - DEN
1 stop6h 04mDelta
Deal found 11/29$299
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:59 pmDEN - GSP
1 stop17h 24mMultiple Airlines
Wed 12/244:40 pmGSP - DEN
2 stops31h 56mMultiple Airlines
Deal found 11/29$303
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:59 pmDEN - GSP
1 stop17h 24mMultiple Airlines
Sun 12/2111:33 amGSP - DEN
2 stops28h 08mMultiple Airlines
Deal found 11/29$310
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:59 pmDEN - GSP
1 stop17h 24mMultiple Airlines
Tue 12/239:38 pmGSP - DEN
2 stops22h 06mMultiple Airlines
Deal found 11/29$322
This Delta deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/143:14 pmDEN - GSP
1 stop6h 26mDelta
Sat 12/206:23 pmGSP - DEN
1 stop6h 09mDelta
Deal found 11/29$324
This Delta deal was found by Cheapflights users on 11/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:50 amDEN - GSP
1 stop6h 12mDelta
Tue 12/1610:08 amGSP - DEN
1 stop5h 59mDelta
Deal found 11/27$329
This Kiwi.com deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1411:59 pmDEN - GSP
1 stop17h 24mMultiple Airlines
Sat 12/209:41 pmGSP - DEN
2 stops25h 50mMultiple Airlines
Deal found 11/29$333
This Delta deal was found by Cheapflights users on 11/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:45 amDEN - GSP
1 stop6h 53mDelta
Wed 12/247:30 amGSP - DEN
1 stop8h 36mDelta
Deal found 11/29$344

Cheap flight deals from Denver to Greenville

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Greenville (GSP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$247
(Kiwi.com)

One-way from

$145
(Kiwi.com)

Popular in

December

Cheapest in

February

Average price

$493

Good round-trip deal

$335 or less

Good one-way deal

$253 or less
Provider with most accurate pricing for Denver Intl-Greenville flight deals.
Search Deals
Provider most trusted by Cheapflights users for Denver Intl-Greenville flights.
Search Deals
From Denver Intl to Greenville
Search Deals
One-way flight from Denver Intl to Greenville
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Denver Intl to Greenville.
Search Deals
Price to beat on a one-way flight from Denver Intl to Greenville.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Denver to Greenville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
Use the filters below to find and compare flights from Denver to Greenville that are best for you.

Fly from

Denver

Fly to

Greenville

Route

Depart

Return

Price

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 4/8

10:05 am-3:13 pm

Nonstop3h 08m

Greenville

Sat 4/11

4:18 pm-6:02 pm

Nonstop3h 44m

$249

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Thu 2/26

10:50 am-8:19 pm

1 stop7h 29m

Greenville

Sun 3/1

7:40 pm-12:25 am

1 stop6h 45m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 1/30

6:23 am-1:17 pm

1 stop4h 54m

Greenville

Sun 2/1

5:40 pm-9:16 pm

1 stop5h 36m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 2/27

3:07 pm-10:24 pm

1 stop5h 17m

Greenville

Fri 3/6

7:20 am-1:35 pm

1 stop8h 15m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 1/28

11:15 am-8:47 pm

1 stop7h 32m

Greenville

Sat 1/31

10:00 am-2:46 pm

1 stop6h 46m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Tue 4/21

12:59 am-9:28 am

1 stop6h 29m

Greenville

Thu 4/30

7:15 am-2:02 pm

1 stop8h 47m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Fri 2/27

12:59 am-9:16 am

1 stop6h 17m

Greenville

Tue 3/3

5:40 am-9:41 am

1 stop6h 01m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 4/8

11:38 am-9:31 pm

1 stop7h 53m

Greenville

Sat 4/11

5:40 am-11:54 am

1 stop8h 14m

$269

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 3/4

6:45 am-5:40 pm

2 stops8h 55m

Greenville

Mon 3/9

6:25 pm-12:25 am

1 stop8h 00m

$274

DenverGreenville

DEN - GSP

DENGSP

Denver Intl

Wed 1/7

7:00 am-5:35 pm

2 stops8h 35m

Greenville

Sun 1/11

10:45 am-2:35 pm

1 stop5h 50m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/26

Showing 1-10 of 16 results
1
2

Compare providers for flights from Denver to Greenville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Greenville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Denver-Greenville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Denver-Greenville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Denver-Greenville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Denver-Greenville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Greenville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Denver to Greenville

Have a flexible travel schedule? Discover the best time to fly to Greenville from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Greenville

How far ahead should I book a flight from Denver to Greenville?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Greenville. Price data was last updated on November 21, 2025.

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Denver to Greenville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Denver to Greenville?

Currently, April is the cheapest month in which you can book a flight from Denver to Greenville (average of $62). Flying from Denver to Greenville in November is currently the most expensive (average of $141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to GSP?

Find hourly flight availability from Denver to Greenville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 29, 2025.

It’s typically best to fly out from Denver to Greenville in the evening. Doing so could potentially save you 31% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Denver to Greenville?

Use this chart to determine the cheapest time to fly round-trip from Denver to Greenville. Price data was last updated on November 29, 2025.

Travelers seeking maximum savings on their Denver to Greenville flight should consider departing on Monday evenings when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Greenville

Get insights into the airlines that provide service to Greenville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Greenville. Reviews last updated November 29, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Denver to Greenville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,255 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,255 reviews
Southwest
8.0
Very good
4,255 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,012 reviews
Southwest
8.0
Very good
4,255 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,058 reviews
Southwest
8.0
Very good
4,255 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,044 reviews
Southwest
8.0
Very good
4,255 reviews

Crew

8.6

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Denver to Greenville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Denver to Greenville flight route?

    Within the past month, 2 users have taken a look at flights from Denver Intl to Greenville.

  • How long is the flight from Denver to Greenville?

    United Airlines, Delta, and Southwest can get you from Denver to Greenville in just under 3h 15m. Your travel time can differ by up to 5h 20m. Airlines will cover a distance of 1275 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Denver to Greenville round-trip?

    Flying on American Airlines is currently your cheapest option to Greenville, with prices starting at $198. Additional round-trip tickets that might be worth considering are offered by Delta and Southwest, with the lowest prices starting at $236 and $268, respectively. These flights start at 53% lower than the current average price 3 months from now.

  • What are the cheapest flights from Denver to Greenville?

    While on average a flight from Denver to Greenville is generally $449, our data shows the cheapest flight currently is $154. When looking at the most popular route, (Denver Intl - Greenville), you can expect to pay $207 for that flight.

  • Can I find deals for flights from Denver to Greenville that include hotel bookings?

    Yes. In addition to deals on Denver to Greenville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Greenville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Greenville.

  • Can I find deals for business class flights from Denver to Greenville?

    Yes. Cheapflights offers flight deals from Denver to Greenville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Greenville?

    Currently, April is the cheapest month in which you can book a flight from Denver to Greenville (average of $62). Flying from Denver to Greenville in November is currently the most expensive (average of $141). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Greenville?

Book flights to Greenville if you plan to visit one of these locations
Simpsonville
Duncan
Greer
Seneca
Anderson

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Top 4 airlines flying from Denver to Greenville

Discover the top 4 airlines that operate flights from Denver to Greenville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$198Average$368FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$321FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$268Average$481FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$269Average$492FlexibilityNo cancel feeOn-time69%

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