$133+ Cheap flights from South Carolina to Grand Cayman
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/14. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
May 18 — May 251
Round-trip
1 adult, Economy
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Find cheap flights from South Carolina to Grand Cayman with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from South Carolina to Grand CaymanExplore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
Explore the most affordable flight options available from South Carolina to Grand Cayman. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
CHS
- GCM
1 stop7h 40m
Delta
Wed 4/291:25 pm
GCM
- CHS
1 stop7h 30m
Delta
Deal found 4/17![Delta logo]()
$419
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:48 pm
CLT
- GCM
1 stop9h 27m
Multiple Airlines
Thu 5/287:00 am
GCM
- CLT
2 stops14h 01m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$419
This Air Canada deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:35 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Mon 6/112:25 pm
GCM
- CLT
1 stop25h 32m
Air Canada
Deal found 4/14![Air Canada logo]()
$423
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:21 pm
CHS
- GCM
2 stops15h 34m
American Airlines
Mon 4/272:10 pm
GCM
- CHS
2 stops18h 42m
American Airlines
Deal found 4/14![American Airlines logo]()
$424
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:48 pm
CLT
- GCM
1 stop9h 47m
Multiple Airlines
Fri 5/225:05 pm
GCM
- CLT
1 stop23h 08m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:00 am
CHS
- GCM
2 stops9h 10m
American Airlines
Sat 5/92:10 pm
GCM
- CHS
2 stops17h 21m
American Airlines
Deal found 4/16![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:45 am
CLT
- GCM
1 stop6h 50m
Multiple Airlines
Mon 7/134:45 pm
GCM
- CLT
1 stop23h 29m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$435
This Air Canada deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:30 am
CLT
- GCM
1 stop25h 40m
Air Canada
Sun 4/1911:55 am
GCM
- CLT
1 stop8h 05m
Air Canada
Deal found 4/14![Air Canada logo]()
$445
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:45 pm
CLT
- GCM
1 stop19h 50m
Multiple Airlines
Sat 5/308:50 am
GCM
- CLT
1 stop25h 53m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:33 pm
CLT
- GCM
1 stop27h 42m
Multiple Airlines
Wed 7/811:30 am
GCM
- CLT
1 stop28h 44m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$468
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:48 pm
CLT
- GCM
1 stop9h 47m
Multiple Airlines
Sun 5/314:45 pm
GCM
- CLT
1 stop17h 58m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
CHS
- GCM
1 stop16h 14m
American Airlines
Thu 4/3012:35 pm
GCM
- CHS
2 stops10h 49m
American Airlines
Deal found 4/14![American Airlines logo]()
$485
Best flights from South Carolina to Grand CaymanDiscover carefully curated flight deals from South Carolina to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
Discover carefully curated flight deals from South Carolina to Grand Cayman that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 18, 2026.
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:25 am
CHS
- GCM
1 stop6h 35m
Delta
Tue 5/121:19 pm
GCM
- CHS
1 stop9h 40m
Delta
Deal found 4/15![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/27:50 pm
CHS
- GCM
2 stops16h 11m
American Airlines
Mon 7/65:12 pm
GCM
- CHS
2 stops18h 07m
American Airlines
Deal found 4/13![American Airlines logo]()
$424
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:48 pm
CLT
- GCM
1 stop9h 27m
Multiple Airlines
Thu 5/287:00 am
GCM
- CLT
3 stops15h 40m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$553
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:10 am
SAV
- GCM
2 stops7h 00m
Southwest
Fri 6/512:45 pm
GCM
- SAV
2 stops20h 25m
Southwest
Deal found 4/13![Southwest logo]()
$578
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:25 am
CHS
- GCM
1 stop6h 35m
Delta
Tue 5/121:19 pm
GCM
- CHS
1 stop7h 33m
Delta
Deal found 4/15![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:21 pm
CHS
- GCM
2 stops15h 34m
American Airlines
Tue 5/512:00 pm
GCM
- CHS
2 stops19h 32m
American Airlines
Deal found 4/13![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:44 pm
CHS
- GCM
2 stops18h 16m
American Airlines
Tue 5/1212:00 pm
GCM
- CHS
1 stop6h 29m
American Airlines
Deal found 4/15![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:00 am
CHS
- GCM
1 stop8h 10m
American Airlines
Sat 5/92:10 pm
GCM
- CHS
1 stop9h 14m
American Airlines
Deal found 4/13![American Airlines logo]()
$424
This Air Canada deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:45 am
SAV
- GCM
2 stops29h 40m
Air Canada
Sat 8/2910:40 am
GCM
- SAV
2 stops32h 10m
Air Canada
Deal found 4/15![Air Canada logo]()
$1,359
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:45 am
GSP
- GCM
1 stop5h 56m
Delta
Tue 9/112:56 pm
GCM
- GSP
1 stop7h 29m
Delta
Deal found 4/14![Delta logo]()
$625
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:30 am
CLT
- GCM
1 stop7h 11m
Delta
Wed 8/2612:56 pm
GCM
- CLT
1 stop10h 01m
Delta
Deal found 4/14![Delta logo]()
$641
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:30 am
CLT
- GCM
1 stop7h 01m
Delta
Fri 8/712:56 pm
GCM
- CLT
1 stop8h 01m
Delta
Deal found 4/15![Delta logo]()
$641
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:51 am
CAE
- GCM
2 stops11h 20m
American Airlines
Fri 6/55:12 pm
GCM
- CAE
2 stops15h 38m
American Airlines
Deal found 4/14![American Airlines logo]()
$661
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:30 am
SAV
- GCM
1 stop7h 24m
Delta
Fri 6/51:19 pm
GCM
- SAV
1 stop9h 21m
Delta
Deal found 4/13![Delta logo]()
$656
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:09 am
SAV
- GCM
2 stops12h 02m
American Airlines
Fri 6/512:01 pm
GCM
- SAV
1 stop4h 51m
American Airlines
Deal found 4/13![American Airlines logo]()
$661
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:29 pm
CLT
- GCM
1 stop16h 07m
American Airlines
Sat 8/12:19 pm
GCM
- CLT
Nonstop3h 16m
American Airlines
Deal found 4/17![American Airlines logo]()
$666
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 am
CLT
- GCM
1 stop4h 41m
Delta
Sat 8/2912:56 pm
GCM
- CLT
1 stop10h 01m
Delta
Deal found 4/14![Delta logo]()
$676
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:32 pm
GSP
- GCM
2 stops16h 29m
American Airlines
Wed 6/105:12 pm
GCM
- GSP
2 stops14h 06m
American Airlines
Deal found 4/16![American Airlines logo]()
$667
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/48:00 am
CLT
- GCM
1 stop4h 40m
Delta
Sun 10/1112:55 pm
GCM
- CLT
1 stop9h 58m
Delta
Deal found 4/15![Delta logo]()
$676
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:14 am
GSP
- GCM
2 stops10h 57m
American Airlines
Sat 6/134:07 pm
GCM
- GSP
2 stops17h 01m
American Airlines
Deal found 4/13![American Airlines logo]()
$692
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/245:45 am
GSP
- GCM
1 stop6h 56m
Delta
Wed 8/2612:56 pm
GCM
- GSP
1 stop9h 42m
Delta
Deal found 4/14![Delta logo]()
$699
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:45 am
GSP
- GCM
1 stop6h 56m
Delta
Wed 8/2612:56 pm
GCM
- GSP
1 stop9h 42m
Delta
Deal found 4/14![Delta logo]()
$699
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:05 pm
GSP
- GCM
2 stops19h 05m
American Airlines
Wed 8/262:10 pm
GCM
- GSP
2 stops7h 40m
American Airlines
Deal found 4/14![American Airlines logo]()
$704
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:21 am
GSP
- GCM
1 stop7h 09m
American Airlines
Thu 6/45:12 pm
GCM
- GSP
2 stops14h 06m
American Airlines
Deal found 4/13![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:59 am
CLT
- GCM
1 stop5h 32m
Delta
Mon 7/2712:56 pm
GCM
- CLT
1 stop6h 22m
Delta
Deal found 4/14![Delta logo]()
$711
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:53 am
GSP
- GCM
2 stops9h 18m
American Airlines
Mon 6/812:01 pm
GCM
- GSP
2 stops10h 51m
American Airlines
Deal found 4/17![American Airlines logo]()
$710
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:40 am
CAE
- GCM
1 stop7h 14m
Delta
Fri 6/51:19 pm
GCM
- CAE
1 stop9h 28m
Delta
Deal found 4/14![Delta logo]()
$746
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:45 am
GSP
- GCM
1 stop6h 09m
Delta
Sat 5/231:19 pm
GCM
- GSP
1 stop5h 54m
Delta
Deal found 4/13![Delta logo]()
$748
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:45 pm
CAE
- GCM
2 stops17h 50m
United Airlines
Fri 6/51:35 pm
GCM
- CAE
3 stops19h 21m
United Airlines
Deal found 4/14![United Airlines logo]()
$4,716
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am
CAE
- GCM
2 stops10h 08m
American Airlines
Sat 9/511:55 am
GCM
- CAE
1 stop10h 59m
American Airlines
Deal found 4/15![American Airlines logo]()
$1,326
Last-minute flights from South Carolina to Grand CaymanDiscover last-minute flight deals from South Carolina to Grand Cayman. Data last updated April 18, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Grand Cayman. Data last updated April 18, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:30 am
CLT
- GCM
1 stop25h 40m
Air Canada
Sun 4/1911:55 am
GCM
- CLT
1 stop8h 05m
Air Canada
Deal found 4/14![Air Canada logo]()
$445
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
CHS
- GCM
1 stop7h 40m
Delta
Wed 4/291:25 pm
GCM
- CHS
1 stop7h 30m
Delta
Deal found 4/17![Delta logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:21 pm
CHS
- GCM
2 stops15h 34m
American Airlines
Mon 4/272:10 pm
GCM
- CHS
2 stops18h 42m
American Airlines
Deal found 4/14![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
CHS
- GCM
1 stop16h 14m
American Airlines
Thu 4/3012:35 pm
GCM
- CHS
2 stops10h 49m
American Airlines
Deal found 4/14![American Airlines logo]()
$485
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:00 am
CHS
- GCM
2 stops9h 10m
American Airlines
Sat 5/92:10 pm
GCM
- CHS
2 stops17h 21m
American Airlines
Deal found 4/16![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:48 pm
CLT
- GCM
1 stop9h 47m
Multiple Airlines
Fri 5/225:05 pm
GCM
- CLT
1 stop23h 08m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$424
This Mytrip deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:48 pm
CLT
- GCM
1 stop9h 27m
Multiple Airlines
Thu 5/287:00 am
GCM
- CLT
2 stops14h 01m
Multiple Airlines
Deal found 4/17![Multiple Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:09 pm
CHS
- GCM
1 stop21h 02m
American Airlines
Thu 5/2812:01 pm
GCM
- CHS
2 stops10h 58m
American Airlines
Deal found 4/15![American Airlines logo]()
$536
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/244:45 pm
CLT
- GCM
1 stop19h 50m
Multiple Airlines
Sat 5/308:50 am
GCM
- CLT
1 stop25h 53m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$463
This Air Canada deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/273:35 pm
CLT
- GCM
1 stop20h 50m
Air Canada
Mon 6/112:25 pm
GCM
- CLT
1 stop25h 32m
Air Canada
Deal found 4/14![Air Canada logo]()
$423
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:48 pm
CLT
- GCM
1 stop9h 47m
Multiple Airlines
Sun 5/314:45 pm
GCM
- CLT
1 stop17h 58m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:28 pm
CLT
- GCM
2 stops43h 07m
Multiple Airlines
Sat 6/68:50 am
GCM
- CLT
1 stop7h 23m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$489
One-way flights from South Carolina to Grand CaymanSearch for one-way flight options from South Carolina to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
Search for one-way flight options from South Carolina to Grand Cayman. Find affordable one-way fares based on user searches. Data last updated April 18, 2026.
This Expedia deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/149:20 am
CLT
- GCM
1 stop27h 05m
Air Canada
Deal found 4/17![Air Canada logo]()
$133
This Expedia deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/159:20 am
CLT
- GCM
1 stop27h 05m
Air Canada
Deal found 4/16![Air Canada logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1112:48 pm
CLT
- GCM
1 stop9h 27m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$152
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
CHS
- GCM
1 stop7h 40m
Delta
Deal found 4/13![Delta logo]()
$157
This Expedia deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:35 pm
CLT
- GCM
1 stop20h 55m
Air Canada
Deal found 4/15![Air Canada logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:48 pm
CLT
- GCM
1 stop9h 47m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$160
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:21 pm
CHS
- GCM
2 stops15h 34m
American Airlines
Deal found 4/14![American Airlines logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/134:56 pm
CLT
- GCM
1 stop24h 09m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:33 pm
CLT
- GCM
1 stop22h 32m
Multiple Airlines
Deal found 4/14![Multiple Airlines logo]()
$179
This Air Canada deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/113:35 pm
CLT
- GCM
1 stop20h 55m
Air Canada
Deal found 4/14![Air Canada logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:18 pm
CHS
- GCM
3 stops18h 17m
Multiple Airlines
Deal found 4/13![Multiple Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/194:21 pm
GSP
- GCM
2 stops19h 29m
American Airlines
Deal found 4/17![American Airlines logo]()
$297
Find flight deals from South Carolina to Grand Cayman
Keep the following information in mind while searching for South Carolina to Grand Cayman flight deals. Data was last updated April 18, 2026.
Round-trip from | $404 (Mytrip) |
|---|---|
One-way from | $133 (Expedia) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Grand Cayman that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from South Carolina to Grand Cayman that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Wed 5/6
6:25 am-12:00 pm
1 stop6h 35m
George Town Owen Roberts Intl
Tue 5/12
1:19 pm-11:59 pm
1 stop9h 40m
$419
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 5/5
6:25 am-12:00 pm
1 stop6h 35m
George Town Owen Roberts Intl
Tue 5/12
1:19 pm-9:52 pm
1 stop7h 33m
$419
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Thu 7/2
7:50 pm-11:01 am
2 stops16h 11m
George Town Owen Roberts Intl
Mon 7/6
5:12 pm-12:19 pm
2 stops18h 07m
$424
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Fri 5/1
8:21 pm-10:55 am
2 stops15h 34m
George Town Owen Roberts Intl
Tue 5/5
12:00 pm-8:32 am
2 stops19h 32m
$424
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Tue 5/5
5:44 pm-11:00 am
2 stops18h 16m
George Town Owen Roberts Intl
Tue 5/12
12:00 pm-7:29 pm
1 stop6h 29m
$424
CharlestonGeorge Town
CHS - GCM
CHSGCM
Charleston
Wed 5/6
6:00 am-1:10 pm
1 stop8h 10m
George Town Owen Roberts Intl
Sat 5/9
2:10 pm-12:24 am
1 stop9h 14m
$424
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Thu 5/21
12:48 pm-9:15 pm
1 stop9h 27m
George Town Owen Roberts Intl
Thu 5/28
7:00 am-11:40 pm
3 stops15h 40m
$553
SavannahGeorge Town
SAV - GCM
SAVGCM
Savannah/Hilton Head
Fri 5/29
6:10 am-12:10 pm
2 stops7h 00m
George Town Owen Roberts Intl
Fri 6/5
12:45 pm-10:10 am
2 stops20h 25m
$578
GreenvilleGeorge Town
GSP - GCM
GSPGCM
Greenville
Tue 8/25
6:45 am-11:41 am
1 stop5h 56m
George Town Owen Roberts Intl
Tue 9/1
12:56 pm-9:25 pm
1 stop7h 29m
$625
CharlotteGeorge Town
CLT - GCM
CLTGCM
Charlotte Douglas
Tue 8/25
5:30 am-11:41 am
1 stop7h 11m
George Town Owen Roberts Intl
Wed 8/26
12:56 pm-11:57 pm
1 stop10h 01m
$641
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Grand Cayman
Have a flexible travel schedule? Discover the best time to fly to Grand Cayman from South Carolina with our price prediction graph.
CHS-GCM
CLT-GCM
GSP-GCM
SAV-GCM
CAE-GCM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Grand Cayman
USSC-zzLAW
CHS-GCM
CLT-GCM
GSP-GCM
SAV-GCM
What is the cheapest month to book a flight from South Carolina to Grand Cayman?
Currently, November is the cheapest month in which you can book a flight from South Carolina to Grand Cayman (average of $286). Flying from South Carolina to Grand Cayman in July is currently the most expensive (average of $673). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Grand Cayman. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
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Alternative routes for South Carolina to Grand Cayman
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Grand Cayman by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Grand Cayman by cabin class
Find flights from South Carolina to Grand Cayman, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Grand Cayman flights
Browse other South Carolina and Grand Cayman flight options. Last updated on April 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from South Carolina to Grand Cayman
Discover the top 2 airlines that operate flights from South Carolina to Grand Cayman. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$287 | Average$455 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$289 | Average$640 | FlexibilityNo cancel fee | On-time71% |