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Cayman Islands

$209+ Cheap flights from South Carolina to the Cayman Islands

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — GCM
Jul 6 — Jul 131
Sun 7/6
Sun 7/13
1 adult, Economy
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Cheap flight deals from South Carolina to Cayman Islands

Keep the following information in mind while searching for South Carolina to Cayman Islands flight deals. Data was last updated July 1, 2025.

Round-trip from

$489
(Kiwi.com)

One-way from

$209
(American Airlines)
From South Carolina to Cayman Islands
Search Deals
One-way flight from South Carolina to Cayman Islands
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Find flight deals from South Carolina to Cayman Islands

Cheapest flights from South Carolina to Cayman Islands
Explore the most affordable flight options available from South Carolina to Cayman Islands. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 1, 2025.

This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/221:43 pmCLT - GCM
1 stop8h 37mMultiple Airlines
Fri 9/57:00 amGCM - CLT
2 stops13h 24mMultiple Airlines
Deal found 6/29$489
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/158:47 pmCHS - GCM
1 stop15h 13mAmerican Airlines
Sat 11/221:45 pmGCM - CHS
1 stop7h 40mAmerican Airlines
Deal found 6/30$497
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/217:00 amGSP - GCM
1 stop8h 29mAmerican Airlines
Mon 7/2812:25 pmGCM - GSP
1 stop6h 30mAmerican Airlines
Deal found 6/30$519
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/92:48 pmCHS - GCM
1 stop27h 32mMultiple Airlines
Sun 7/1312:40 pmGCM - CHS
1 stop20h 50mMultiple Airlines
Deal found 6/29$558
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:00 amCLT - GCM
Nonstop3h 05mAmerican Airlines
Sun 12/216:10 pmGCM - CLT
Nonstop3h 00mAmerican Airlines
Deal found 6/30$565
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:00 amSAV - GCM
1 stop5h 42mDelta
Sun 10/191:02 pmGCM - SAV
1 stop6h 45mDelta
Deal found 6/29$565
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/304:10 pmCAE - GCM
2 stops22h 02mAmerican Airlines
Sat 9/612:25 pmGCM - CAE
1 stop9h 42mAmerican Airlines
Deal found 6/30$669
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/57:50 amSAV - GCM
1 stop4h 00mAmerican Airlines
Sun 11/91:45 pmGCM - SAV
1 stop9h 48mAmerican Airlines
Deal found 7/1$670
This Delta deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/308:05 amCAE - GCM
1 stop4h 32mDelta
Sat 9/612:52 pmGCM - CAE
1 stop9h 49mDelta
Deal found 6/30$671
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/299:10 amSAV - GCM
1 stop28h 20mUnited Airlines
Sat 8/24:45 pmGCM - SAV
1 stop28h 15mUnited Airlines
Deal found 6/30$701
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/307:00 amCHS - GCM
1 stop6h 30mUnited Airlines
Fri 7/41:35 pmGCM - CHS
1 stop25h 32mUnited Airlines
Deal found 6/29$820
This Mytrip deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:05 pmSAV - GCM
2 stops22h 40mMultiple Airlines
Mon 9/17:00 amGCM - SAV
3 stops30h 04mMultiple Airlines
Deal found 6/30$1,114

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Cayman Islands that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
Use the filters below to find and compare flights from South Carolina to the Cayman Islands that are best for you.

Fly from

South Carolina

Fly to

Cayman Islands

Route

Depart

Return

Price

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Fri 8/22

1:43 pm-9:20 pm

1 stop8h 37m

George Town Owen Roberts Intl

Fri 9/5

7:00 am-9:24 pm

2 stops13h 24m

$489

CharlestonGeorge Town

CHS - GCM

CHSGCM

Charleston

Sat 11/15

8:47 pm-12:00 pm

1 stop15h 13m

George Town Owen Roberts Intl

Sat 11/22

1:45 pm-9:25 pm

1 stop7h 40m

$497

GreenvilleGeorge Town

GSP - GCM

GSPGCM

Greenville

Mon 7/21

7:00 am-2:29 pm

1 stop8h 29m

George Town Owen Roberts Intl

Mon 7/28

12:25 pm-7:55 pm

1 stop6h 30m

$519

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Thu 10/16

7:00 am-11:42 am

1 stop5h 42m

George Town Owen Roberts Intl

Sun 10/19

1:02 pm-8:47 pm

1 stop6h 45m

$565

CharlotteGeorge Town

CLT - GCM

CLTGCM

Charlotte Douglas

Sun 12/14

9:00 am-12:05 pm

Nonstop3h 05m

George Town Owen Roberts Intl

Sun 12/21

6:10 pm-9:10 pm

Nonstop3h 00m

$565

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Sat 8/30

4:10 pm-1:12 pm

2 stops22h 02m

George Town Owen Roberts Intl

Sat 9/6

12:25 pm-11:07 pm

1 stop9h 42m

$669

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Wed 11/5

7:50 am-11:50 am

1 stop4h 00m

George Town Owen Roberts Intl

Sun 11/9

1:45 pm-11:33 pm

1 stop9h 48m

$670

ColumbiaGeorge Town

CAE - GCM

CAEGCM

Columbia Metropolitan

Sat 8/30

8:05 am-11:37 am

1 stop4h 32m

George Town Owen Roberts Intl

Sat 9/6

12:52 pm-11:41 pm

1 stop9h 49m

$671

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Tue 7/29

9:10 am-12:30 pm

1 stop28h 20m

George Town Owen Roberts Intl

Sat 8/2

4:45 pm-10:00 pm

1 stop28h 15m

$701

SavannahGeorge Town

SAV - GCM

SAVGCM

Savannah/Hilton Head

Fri 8/29

3:05 pm-12:45 pm

2 stops22h 40m

George Town Owen Roberts Intl

Mon 9/1

7:00 am-2:04 pm

3 stops30h 04m

$1,114

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Showing 1-10 of 16 results
1
2

Best time to book a flight from South Carolina to Cayman Islands

Have a flexible travel schedule? Discover the best time to fly to Cayman Islands from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to the Cayman Islands

What is the cheapest month to book a flight from South Carolina to Cayman Islands?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cayman Islands

Get insights into the airlines that provide service to Cayman Islands. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cayman Islands. Reviews last updated July 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from South Carolina to the Cayman Islands. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,858 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,665 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cayman Islands. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines to fly from South Carolina to Cayman Islands one-way?

    One-way options have recently been found by users for as low as $209 on American Airlines. Other airlines that offer cheap prices include Air Canada from $244 and Delta from $428 one-way.

  • Can I find deals for flights from South Carolina to Cayman Islands that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cayman Islands flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cayman Islands?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cayman Islands.

  • Can I find deals for business class flights from South Carolina to Cayman Islands?

    Yes. Cheapflights offers flight deals from South Carolina to Cayman Islands by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cayman Islands?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Cayman Islands (average of $467). Flying from South Carolina to Cayman Islands in March is currently the most expensive (average of $594). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from South Carolina to Cayman Islands

Discover the top 2 airlines that operate flights from South Carolina to Cayman Islands. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$428Average$605FlexibilityNo cancel feeOn-time71%
DeltaCheapest$460Average$627FlexibilityNo cancel feeOn-timeN/A

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