For US-bound flights, expect two security checks at PTY, with the second at the gate. Allow extra time for this process.

Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $417 (Kiwi.com) |
One-way from | $265 (Avianca Connect) |
Popular in | March |
Cheapest in | August |
Average price | $888 |
Good round-trip deal | $589 or less |
Good one-way deal | $382 or less |
Fly from
Fly to
Route
Depart
Return
Price
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
mar. 1/20
3:50 pm-2:37 pm
1 stop23h 47m
Houston George Bush Intcntl
vie. 2/20
7:30 am-10:30 am
1 stop26h 00m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
mar. 12/23
3:50 pm-4:35 pm
1 stop25h 45m
Houston George Bush Intcntl
mié. 12/31
9:30 am-6:55 pm
1 stop8h 25m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
vie. 12/26
3:50 pm-4:35 pm
1 stop25h 45m
Houston George Bush Intcntl
sáb. 1/17
7:30 am-6:55 pm
1 stop10h 25m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
vie. 12/26
7:50 pm-5:40 pm
2 stops22h 50m
Houston George Bush Intcntl
mié. 12/31
10:44 am-7:55 pm
1 stop8h 11m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
mié. 1/7
8:11 am-5:40 pm
1 stop10h 29m
Houston George Bush Intcntl
mié. 1/14
1:00 pm-10:30 am
1 stop20h 30m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
mar. 12/23
3:50 pm-4:35 pm
1 stop25h 45m
Houston George Bush Intcntl
dom. 12/28
9:30 am-10:30 am
1 stop24h 00m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
dom. 3/8
7:50 pm-12:05 pm
1 stop16h 15m
Houston George Bush Intcntl
mié. 3/11
5:35 pm-10:30 am
1 stop16h 55m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
mar. 1/6
6:10 pm-5:40 pm
2 stops24h 30m
Houston George Bush Intcntl
mar. 1/13
10:15 am-7:51 pm
1 stop8h 36m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
vie. 12/26
7:50 pm-4:35 pm
1 stop21h 45m
Panama CityHouston
PTY - IAH
PTYIAH
Panama City Tocumen Intl
dom. 12/21
7:50 pm-4:35 pm
1 stop21h 45m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
Currently, January is the cheapest month in which you can book a flight from Panama City to Houston George Bush Intcntl Airport (average of $457). Flying from Panama City to Houston George Bush Intcntl Airport in March is currently the most expensive (average of $988). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
It’s typically best to fly out from Panama City to Houston George Bush Intcntl Airport in the evening. Doing so could potentially save you 10% on the flight price compared to flying at noon, which is usually more expensive.
About 8% of weekly flights between Panama City and Houston have experienced delays in the past year, with the average delay time being 180 minutes.
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
Monday tends to have the lowest number of delays on this route, whereas Saturday has historically faced a higher average of delays compared to other days of the week.
Over the last year, United Airlines have had the lowest number of delays on this route, with just 8% of flights being delayed.
Crew
Food
Boarding
Comfort
Entertainment
Overall
Reviews
Anonymous,Dec 2025
AMS - EWR
Crew
Food
Boarding
Comfort
Entertainment
Overall
Reviews
Anonymous,Dec 2025
AMS - EWR
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$781 | Average$1,016 | FlexibilityNo cancel fee | On-time69% |