$347+ Cheap flights from Panama City (PTY) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — HOU
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Houston
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Cheapest flights from Panama City to HoustonExplore the most affordable flight options available from Panama City to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Panama City to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:34 pm -
1 stop18h 41m
Tue 10/2712:24 pm -
1 stop8h 07m
Deal found 9/11![Multiple Airlines logo]()
$616
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:33 pm -
2 stops24h 57m
Tue 10/136:05 am -
1 stop14h 26m
Deal found 9/10![Multiple Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:39 pm -
2 stops15h 40m
Tue 10/2012:17 pm -
1 stop8h 14m
Deal found 9/12![Multiple Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:01 am -
2 stops14h 22m
Tue 10/2012:17 pm -
1 stop8h 14m
Deal found 9/10![Multiple Airlines logo]()
$632
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:33 pm -
2 stops33h 46m
Wed 10/288:21 pm -
1 stop24h 10m
Deal found 9/13![Multiple Airlines logo]()
$634
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:33 pm -
1 stop15h 42m
Tue 10/136:05 am -
1 stop14h 26m
Deal found 9/14![Multiple Airlines logo]()
$639
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:33 pm -
1 stop15h 42m
Sat 10/249:12 pm -
1 stop23h 19m
Deal found 9/12![Multiple Airlines logo]()
$642
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:34 pm -
2 stops16h 48m
Tue 10/276:05 am -
1 stop14h 26m
Deal found 9/15![Multiple Airlines logo]()
$643
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop8h 39m
Tue 10/273:09 pm -
1 stop21h 50m
Deal found 9/15![Delta logo]()
$874
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop23h 43m
Mon 10/265:28 pm -
1 stop19h 31m
Deal found 9/11![Delta logo]()
$895
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:24 pm -
1 stop19h 44m
Thu 10/1511:12 am -
1 stop25h 47m
Deal found 9/10![Delta logo]()
$949
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:24 pm -
1 stop26h 09m
Thu 10/2211:12 am -
1 stop25h 47m
Deal found 9/15![Delta logo]()
$956
Best flights from Panama City to HoustonDiscover carefully curated flight deals from Panama City to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Panama City to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop8h 39m
Tue 10/273:09 pm -
1 stop21h 50m
Deal found 9/15![Delta logo]()
$874
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:41 pm -
Nonstop4h 27m
Thu 11/52:27 pm -
Nonstop4h 11m
Deal found 9/14![United Airlines logo]()
$986
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:10 pm -
3 stops28h 15m
Sun 10/1812:05 pm -
2 stops25h 50m
Deal found 9/14![Multiple Airlines logo]()
$1,096
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop8h 39m
Mon 10/263:09 pm -
1 stop21h 50m
Deal found 9/15![Delta logo]()
$874
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:24 pm -
1 stop23h 43m
Mon 10/263:09 pm -
1 stop21h 50m
Deal found 9/15![Delta logo]()
$874
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:55 am -
Nonstop4h 20m
Mon 11/99:34 am -
Nonstop4h 11m
Deal found 9/13![United Airlines logo]()
$986
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 34m
Mon 12/287:00 am -
1 stop13h 43m
Deal found 9/10![Delta logo]()
$885
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1611:35 am -
Nonstop4h 19m
Tue 2/239:34 am -
Nonstop4h 11m
Deal found 9/11![United Airlines logo]()
$986
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:29 pm -
1 stop8h 52m
Tue 11/176:00 am -
1 stop7h 02m
Deal found 9/11![Delta logo]()
$895
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:55 am -
Nonstop4h 20m
Mon 12/282:27 pm -
Nonstop4h 11m
Deal found 9/13![United Airlines logo]()
$986
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/203:30 pm -
Nonstop4h 26m
Tue 10/279:34 am -
Nonstop4h 11m
Deal found 9/15![United Airlines logo]()
$986
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:24 pm -
1 stop19h 44m
Thu 10/1511:12 am -
1 stop25h 47m
Deal found 9/10![Delta logo]()
$949
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:30 pm -
Nonstop4h 26m
Wed 10/289:34 am -
Nonstop4h 11m
Deal found 9/13![United Airlines logo]()
$1,013
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:24 pm -
1 stop26h 09m
Thu 10/2211:12 am -
1 stop25h 47m
Deal found 9/15![Delta logo]()
$956
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
Nonstop4h 27m
Fri 1/12:27 pm -
Nonstop4h 11m
Deal found 9/14![United Airlines logo]()
$1,013
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/253:29 pm -
1 stop8h 52m
Mon 11/306:00 am -
1 stop7h 02m
Deal found 9/15![Delta logo]()
$1,013
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:30 pm -
Nonstop4h 26m
Tue 10/1310:03 am -
Nonstop4h 11m
Deal found 9/10![United Airlines logo]()
$1,066
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:55 am -
Nonstop4h 20m
Tue 11/109:34 am -
Nonstop4h 11m
Deal found 9/13![United Airlines logo]()
$1,093
Last-minute flights from Panama City to HoustonDiscover last-minute flight deals from Panama City to Houston. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Houston. Data last updated September 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:33 pm -
2 stops24h 57m
Tue 10/136:05 am -
1 stop14h 26m
Deal found 9/10![Multiple Airlines logo]()
$625
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:33 pm -
1 stop15h 42m
Tue 10/136:05 am -
1 stop14h 26m
Deal found 9/14![Multiple Airlines logo]()
$639
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/82:24 pm -
1 stop19h 44m
Thu 10/1511:12 am -
1 stop25h 47m
Deal found 9/10![Delta logo]()
$949
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:39 pm -
2 stops15h 40m
Tue 10/2012:17 pm -
1 stop8h 14m
Deal found 9/12![Multiple Airlines logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:01 am -
2 stops14h 22m
Tue 10/2012:17 pm -
1 stop8h 14m
Deal found 9/10![Multiple Airlines logo]()
$632
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/152:24 pm -
1 stop26h 09m
Thu 10/2211:12 am -
1 stop25h 47m
Deal found 9/15![Delta logo]()
$956
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/189:33 pm -
2 stops33h 46m
Wed 10/288:21 pm -
1 stop24h 10m
Deal found 9/13![Multiple Airlines logo]()
$634
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:34 pm -
2 stops16h 48m
Tue 10/276:05 am -
1 stop14h 26m
Deal found 9/15![Multiple Airlines logo]()
$643
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop8h 39m
Tue 10/273:09 pm -
1 stop21h 50m
Deal found 9/15![Delta logo]()
$874
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:24 pm -
1 stop23h 43m
Mon 10/265:28 pm -
1 stop19h 31m
Deal found 9/11![Delta logo]()
$895
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:34 pm -
1 stop18h 41m
Tue 10/2712:24 pm -
1 stop8h 07m
Deal found 9/11![Multiple Airlines logo]()
$616
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:33 pm -
1 stop15h 42m
Sat 10/249:12 pm -
1 stop23h 19m
Deal found 9/12![Multiple Airlines logo]()
$642
One-way flights from Panama City to HoustonSearch for one-way flight options from Panama City to Houston. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Panama City to Houston. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/63:39 pm -
2 stops15h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:15 pm -
2 stops17h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:31 pm -
1 stop17h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/119:33 pm -
2 stops33h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/33:39 pm -
2 stops15h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:30 am -
2 stops15h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$418
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1412:03 pm -
2 stops20h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:33 pm -
2 stops24h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$422
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/259:33 pm -
2 stops24h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:23 pm -
1 stop8h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$470
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/113:29 pm -
1 stop8h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$481
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1110:34 am -
3 stops37h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Multiple Airlines logo]()
$546
Find flight deals from Panama City to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Round-trip from | $616 (Kiwi.com) |
|---|---|
One-way from | $347 (Kiwi.com) |
Popular in | January |
Cheapest in | February |
Average price | $900 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Panama City to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sun 11/22
12:33 pm-8:44 am
1 stop21h 11m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$389
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Wed 11/11
4:00 pm-7:23 am
2 stops16h 23m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$394
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sat 11/14
12:03 pm-7:23 am
2 stops20h 20m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$419
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Mon 9/28
9:33 pm-10:30 pm
2 stops24h 57m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$422
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Fri 9/25
9:33 pm-10:30 pm
2 stops24h 57m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$424
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sat 11/7
9:00 am-1:00 pm
1 stop29h 00m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$431
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Wed 9/23
9:33 pm-1:33 pm
1 stop16h 00m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$452
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sat 12/26
2:50 pm-7:35 am
2 stops17h 45m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$460
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Thu 9/24
6:34 pm-1:33 pm
1 stop18h 59m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$461
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Mon 2/8
3:20 pm-11:58 pm
1 stop9h 38m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$470
Showing 1-10 of 39 resultsSorted by cheapest first
Best time to book a flight from Panama City to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Panama City with our price prediction graph.
PTY-HO1
PTY-IAH
PTY-HOU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Houston
PTY-HO1
PTY-IAH
PTY-HOU
What is the cheapest month to book a flight from Panama City to Houston?
Currently, February is the cheapest month in which you can book a flight from Panama City to Houston (average of $870). Flying from Panama City to Houston in January is currently the most expensive (average of $1,121). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to HOU?
Find hourly flight availability from Panama City to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Houston as you normally would.
How much does it cost to fly round-trip from Panama City to Houston?
Airfare is below average for this route at the moment.
Panama City to Houston flights typically cost between $702 and $949 in October.The cheapest round-trip price found within the last 5 days was $616 on Multiple Airlines (Oct 21-Oct 27).
How often are flights from Panama City to Houston delayed?
About 5% of weekly flights between Panama City and Houston have experienced delays in the past year, with the average delay time being 132 minutes.
What is the most punctual flight time for Panama City to Houston flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Houston flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
The best insider tips for Panama City to Houston flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Panama City to Houston trip
Our travel experts
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated September 15, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Panama City to Houston by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Entertainment
6.9
Food
6.9
Comfort
7.4
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Crew
8.1
Entertainment
6.9
Food
6.9
Comfort
7.4
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Crew
8.1
Entertainment
6.9
Food
6.9
Comfort
7.4
Overall
7.6
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Houston
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Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Houston by cabin class
Find flights from Panama City to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Houston flights
Browse other Panama City and Houston flight options. Last updated on September 15, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Houston
Discover the top 2 airlines that operate flights from Panama City to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$533 | Average$1,071 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$857 | Average$1,096 | FlexibilityNo cancel fee | On-time70% |