$317+ Cheap flights from Panama City (PTY) to Houston
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — HOU
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Houston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to HoustonExplore the most affordable flight options available from Panama City to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Panama City to Houston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 pm -
1 stop14h 44m
Fri 11/279:39 am -
1 stop9h 06m
Deal found 10/30![Multiple Airlines logo]()
$590
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 pm -
1 stop15h 30m
Thu 11/269:39 am -
1 stop9h 50m
Deal found 11/2![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:31 pm -
1 stop12h 14m
Wed 11/259:39 am -
1 stop9h 06m
Deal found 11/3![Multiple Airlines logo]()
$622
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:00 pm -
1 stop17h 45m
Mon 12/78:32 pm -
1 stop16h 14m
Deal found 11/2![Multiple Airlines logo]()
$649
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:30 pm -
2 stops24h 01m
Mon 12/78:32 pm -
1 stop16h 14m
Deal found 10/30![Multiple Airlines logo]()
$659
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
1 stop12h 13m
Thu 11/269:39 am -
1 stop9h 06m
Deal found 11/3![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 pm -
2 stops14h 08m
Mon 11/162:32 pm -
1 stop14h 13m
Deal found 10/30![Multiple Airlines logo]()
$687
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 02m
Tue 12/86:12 am -
1 stop6h 51m
Deal found 11/3![Delta logo]()
$949
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:29 pm -
1 stop9h 02m
Sun 1/36:00 am -
1 stop14h 45m
Deal found 11/3![Delta logo]()
$976
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:33 pm -
2 stops19h 32m
Sun 1/38:05 pm -
2 stops18h 28m
Deal found 10/30![American Airlines logo]()
$990
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:13 pm -
2 stops20h 50m
Wed 2/247:08 pm -
2 stops17h 17m
Deal found 11/1![American Airlines logo]()
$995
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
1 stop11h 06m
Fri 1/86:00 am -
1 stop14h 51m
Deal found 11/3![Delta logo]()
$1,003
Best flights from Panama City to HoustonDiscover carefully curated flight deals from Panama City to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Panama City to Houston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/168:55 am -
Nonstop4h 20m
Mon 12/282:27 pm -
Nonstop4h 11m
Deal found 11/2![United Airlines logo]()
$944
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 29m
Mon 12/287:00 am -
1 stop13h 45m
Deal found 11/2![Delta logo]()
$949
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:33 pm -
2 stops19h 32m
Sun 1/38:05 pm -
2 stops18h 28m
Deal found 10/30![American Airlines logo]()
$990
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:41 pm -
Nonstop4h 27m
Thu 12/242:27 pm -
Nonstop4h 11m
Deal found 10/30![United Airlines logo]()
$944
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 02m
Tue 12/86:12 am -
1 stop6h 51m
Deal found 11/3![Delta logo]()
$949
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:41 pm -
Nonstop4h 27m
Mon 12/282:27 pm -
Nonstop4h 11m
Deal found 11/2![United Airlines logo]()
$944
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/222:25 pm -
2 stops20h 54m
Tue 3/25:41 pm -
2 stops18h 44m
Deal found 11/4![American Airlines logo]()
$1,051
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/233:28 pm -
1 stop8h 47m
Sun 1/310:38 am -
1 stop10h 07m
Deal found 10/30![Delta logo]()
$976
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/304:41 pm -
Nonstop4h 27m
Mon 12/79:34 am -
Nonstop4h 11m
Deal found 11/2![United Airlines logo]()
$944
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 02m
Sat 2/276:00 am -
1 stop6h 55m
Deal found 11/1![Delta logo]()
$976
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2311:35 am -
Nonstop4h 20m
Thu 12/3112:00 pm -
Nonstop4h 12m
Deal found 11/3![United Airlines logo]()
$965
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
1 stop11h 06m
Fri 1/86:00 am -
1 stop14h 51m
Deal found 11/2![Delta logo]()
$1,003
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/174:41 pm -
Nonstop4h 27m
Fri 1/12:27 pm -
Nonstop4h 11m
Deal found 11/1![United Airlines logo]()
$970
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:29 pm -
1 stop9h 02m
Tue 12/226:00 am -
1 stop14h 45m
Deal found 10/31![Delta logo]()
$1,058
This Delta deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 02m
Mon 12/76:12 am -
1 stop6h 51m
Deal found 10/30![Delta logo]()
$1,110
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/263:29 pm -
1 stop8h 52m
Sun 11/296:00 am -
1 stop7h 02m
Deal found 11/3![Delta logo]()
$1,137
Last-minute flights from Panama City to HoustonDiscover last-minute flight deals from Panama City to Houston. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Houston. Data last updated November 4, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 pm -
2 stops14h 08m
Mon 11/162:32 pm -
1 stop14h 13m
Deal found 10/30![Multiple Airlines logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 pm -
1 stop15h 30m
Thu 11/269:39 am -
1 stop9h 50m
Deal found 11/2![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:31 pm -
1 stop12h 14m
Wed 11/259:39 am -
1 stop9h 06m
Deal found 11/3![Multiple Airlines logo]()
$622
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:00 pm -
1 stop17h 45m
Mon 12/78:32 pm -
1 stop16h 14m
Deal found 11/2![Multiple Airlines logo]()
$649
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/209:31 pm -
1 stop12h 13m
Thu 11/269:39 am -
1 stop9h 06m
Deal found 11/3![Multiple Airlines logo]()
$671
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/217:00 pm -
1 stop14h 44m
Fri 11/279:39 am -
1 stop9h 06m
Deal found 10/30![Multiple Airlines logo]()
$590
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:30 pm -
2 stops24h 01m
Mon 12/78:32 pm -
1 stop16h 14m
Deal found 10/30![Multiple Airlines logo]()
$659
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/13:29 pm -
1 stop9h 02m
Tue 12/86:12 am -
1 stop6h 51m
Deal found 11/3![Delta logo]()
$949
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/53:13 pm -
2 stops20h 50m
Wed 2/247:08 pm -
2 stops17h 17m
Deal found 11/1![American Airlines logo]()
$995
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:29 pm -
1 stop9h 02m
Sun 1/36:00 am -
1 stop14h 45m
Deal found 11/3![Delta logo]()
$976
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:33 pm -
2 stops19h 32m
Sun 1/38:05 pm -
2 stops18h 28m
Deal found 10/30![American Airlines logo]()
$990
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/278:00 am -
1 stop11h 06m
Fri 1/86:00 am -
1 stop14h 51m
Deal found 11/3![Delta logo]()
$1,003
One-way flights from Panama City to HoustonSearch for one-way flight options from Panama City to Houston. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Panama City to Houston. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/189:31 pm -
1 stop12h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:30 pm -
1 stop20h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$319
This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:30 pm -
2 stops18h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:48 pm -
1 stop13h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:48 pm -
1 stop13h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:31 pm -
1 stop17h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/182:49 pm -
3 stops33h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Aeromexico logo]()
$552
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:03 pm -
2 stops27h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$648
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:10 pm -
2 stops29h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$654
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:28 pm -
3 stops49h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$697
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:11 pm -
2 stops20h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$768
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:11 pm -
2 stops29h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$784
Find flight deals from Panama City to Houston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Houston (HO1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Round-trip from | $590 (Kiwi.com) |
|---|---|
One-way from | $317 (Kiwi.com) |
Popular in | November |
Cheapest in | February |
Average price | $1,287 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Houston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Panama City to Houston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sun 12/6
9:48 pm-8:45 am
2 stops35h 57m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$365
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Fri 11/13
12:03 pm-2:44 pm
1 stop27h 41m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$392
Panama CityHouston
PTY Panama City Tocumen Intl - HOU Houston Hobby
PTYHOU
Panama City Tocumen Intl
Thu 11/12
12:03 pm-2:09 pm
2 stops27h 06m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$648
Panama CityHouston
PTY Panama City Tocumen Intl - HOU Houston Hobby
PTYHOU
Panama City Tocumen Intl
Fri 12/18
7:10 pm-11:15 pm
2 stops29h 05m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$654
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sat 11/14
10:05 am-8:19 am
3 stops23h 14m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$683
Panama CityHouston
PTY Panama City Tocumen Intl - HOU Houston Hobby
PTYHOU
Panama City Tocumen Intl
Mon 11/16
7:11 pm-11:21 pm
2 stops29h 10m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$784
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Fri 1/1
5:30 am-11:05 am
1 stop6h 35m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$840
Panama CityHouston
PTY Panama City Tocumen Intl - HOU Houston Hobby
PTYHOU
Panama City Tocumen Intl
Sat 11/14
8:03 am-11:21 pm
2 stops16h 18m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$844
Panama CityHouston
PTY Panama City Tocumen Intl - HOU Houston Hobby
PTYHOU
Panama City Tocumen Intl
Sat 12/19
2:41 pm-11:56 pm
2 stops10h 15m
Houston Hobby
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$857
Panama CityHouston
PTY Panama City Tocumen Intl - IAH Houston George Bush Intcntl
PTYIAH
Panama City Tocumen Intl
Sat 1/2
5:30 am-11:05 am
1 stop6h 35m
Houston George Bush Intcntl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$858
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Panama City to Houston
Have a flexible travel schedule? Discover the best time to fly to Houston from Panama City with our price prediction graph.
PTY-HO1
PTY-IAH
PTY-HOU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Houston
PTY-HO1
PTY-IAH
PTY-HOU
What is the cheapest month to book a flight from Panama City to Houston?
Currently, February is the cheapest month in which you can book a flight from Panama City to Houston (average of $865). Flying from Panama City to Houston in November is currently the most expensive (average of $1,289). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PTY to HOU?
Find hourly flight availability from Panama City to Houston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Houston as you normally would.
How much does it cost to fly round-trip from Panama City to Houston?
Airfare is below average for this route at the moment.
Panama City to Houston flights typically cost between $1,287 and $1,291 in November.The cheapest round-trip price found within the last 5 days was $590 on Multiple Airlines (Nov 21-Nov 27).
How often are flights from Panama City to Houston delayed?
About 5% of weekly flights between Panama City and Houston have experienced delays in the past year, with the average delay time being 130 minutes.
What is the most punctual flight time for Panama City to Houston flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Tuesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Panama City to Houston flights?
Over the last year, United Airlines have had the lowest number of delays on this route, with just 5% of flights being delayed.
The best insider tips for Panama City to Houston flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Panama City to Houston trip
Our travel experts
Reviews of airlines servicing Houston
Get insights into the airlines that provide service to Houston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Houston. Reviews last updated November 4, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Panama City to Houston by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
7.6
Comfort
7.4
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Food
7.0
Overall
7.6
Comfort
7.4
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Food
7.0
Overall
7.6
Comfort
7.4
Entertainment
6.9
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama City to Houston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Houston
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Complete your trip
Complete your trip to Houston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Houston by cabin class
Find flights from Panama City to Houston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Houston flights
Browse other Panama City and Houston flight options. Last updated on November 4, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on November 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Houston
Discover the top 2 airlines that operate flights from Panama City to Houston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$533 | Average$1,097 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$857 | Average$1,180 | FlexibilityNo cancel fee | On-time70% |