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$308+ Cheap flights from Louisville to Gainesville (SDF - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — GNV
May 17 — May 241
Sun 5/17
Sun 5/24
1 adult, Economy
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Cheap flight deals from Louisville to Gainesville

Cheapest flights from Louisville to Gainesville
Explore the most affordable flight options available from Louisville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.

This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
SDF
-
GNV
1 stop3h 29m
Delta
Sat 8/17:00 am
GNV
-
SDF
1 stop4h 51m
Delta
Deal found 4/14$402
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:19 pm
SDF
-
GNV
1 stop3h 54m
American Airlines
Sat 8/19:48 am
GNV
-
SDF
2 stops10h 08m
American Airlines
Deal found 4/14$407
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3010:00 am
SDF
-
GNV
1 stop4h 56m
Delta
Sun 8/26:33 am
GNV
-
SDF
1 stop5h 18m
Delta
Deal found 4/13$427
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:00 pm
SDF
-
GNV
1 stop5h 17m
Delta
Fri 5/81:11 pm
GNV
-
SDF
1 stop3h 50m
Delta
Deal found 4/16$451
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/512:11 pm
SDF
-
GNV
2 stops9h 33m
American Airlines
Tue 5/126:49 pm
GNV
-
SDF
1 stop4h 41m
American Airlines
Deal found 4/15$456
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
SDF
-
GNV
1 stop3h 24m
Delta
Mon 5/117:05 pm
GNV
-
SDF
1 stop3h 31m
Delta
Deal found 4/16$457
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
SDF
-
GNV
1 stop3h 24m
Delta
Tue 5/54:59 pm
GNV
-
SDF
1 stop4h 32m
Delta
Deal found 4/16$475
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
SDF
-
GNV
2 stops8h 33m
American Airlines
Sat 5/26:00 am
GNV
-
SDF
1 stop6h 12m
American Airlines
Deal found 4/13$480
This Delta deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/306:00 am
SDF
-
GNV
1 stop3h 24m
Delta
Wed 5/67:03 pm
GNV
-
SDF
1 stop4h 56m
Delta
Deal found 4/16$481
This American Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:16 am
SDF
-
GNV
2 stops8h 17m
American Airlines
Wed 5/66:30 am
GNV
-
SDF
2 stops9h 35m
American Airlines
Deal found 4/17$485
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:30 am
SDF
-
GNV
1 stop6h 47m
American Airlines
Mon 5/45:47 pm
GNV
-
SDF
1 stop4h 21m
American Airlines
Deal found 4/15$487

Find flight deals from Louisville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$402
(Delta)

One-way from

$308
(Delta)
Provider with most accurate pricing for Louisville Intl-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Louisville Intl-Gainesville Regional flights.
Search Deals
From Louisville Intl to Gainesville Regional
Search Deals
One-way flight from Louisville Intl to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Louisville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Louisville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Thu 7/23

6:00 am-9:29 am

1 stop3h 29m

Gainesville Regional

Sat 8/1

7:00 am-11:51 am

1 stop4h 51m

$402

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Thu 7/23

8:19 pm-12:13 am

1 stop3h 54m

Gainesville Regional

Sat 8/1

9:48 am-7:56 pm

2 stops10h 08m

$407

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Thu 7/30

10:00 am-2:56 pm

1 stop4h 56m

Gainesville Regional

Sun 8/2

6:33 am-11:51 am

1 stop5h 18m

$427

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Tue 5/5

9:38 am-1:16 pm

1 stop3h 38m

Gainesville Regional

Tue 5/12

6:38 am-10:25 am

1 stop3h 47m

$451

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Wed 4/29

1:00 pm-6:17 pm

1 stop5h 17m

Gainesville Regional

Fri 5/8

1:11 pm-5:01 pm

1 stop3h 50m

$451

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Thu 4/30

6:00 am-9:24 am

1 stop3h 24m

Gainesville Regional

Fri 5/8

7:05 pm-12:25 am

1 stop5h 20m

$457
Quickest round-trip

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Thu 4/30

6:00 am-9:24 am

1 stop3h 24m

Gainesville Regional

Mon 5/11

7:05 pm-10:36 pm

1 stop3h 31m

$457

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Tue 5/5

11:16 am-9:44 pm

2 stops10h 28m

Gainesville Regional

Tue 5/12

6:25 am-4:05 pm

2 stops9h 40m

$462

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Sat 5/2

11:26 am-4:31 pm

1 stop5h 05m

Gainesville Regional

Tue 5/5

7:03 pm-11:59 pm

1 stop4h 56m

$475

LouisvilleGainesville

SDF - GNV

SDFGNV

Louisville Intl

Tue 4/28

7:05 am-1:16 pm

1 stop6h 11m

Gainesville Regional

Sat 5/2

5:30 pm-11:59 pm

1 stop6h 29m

$475

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/13

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Compare providers for flights from Louisville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Gainesville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Louisville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Louisville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Louisville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Louisville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated April 17, 2026.
See what other customers who have flown with Delta and American Airlines from Louisville to Gainesville have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,406 reviews
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.1
Good
11,593 reviews
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Louisville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Louisville to Gainesville?

    There are many flights that can get you from Louisville to Gainesville in 3h 29m. Fly via Delta or American Airlines to get the fastest option. Airlines will cover a distance of 618 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Louisville to Gainesville round-trip?

    Our cheapest airline available from Louisville to Gainesville is Delta. Our recent data shows that you can find tickets from as low as $325 on this airline. An additional option worth looking into is American Airlines, starting at $361.

  • Can I find deals for flights from Louisville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Louisville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Louisville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Louisville to Gainesville.

  • Can I find deals for business class flights from Louisville to Gainesville?

    Yes. Cheapflights offers flight deals from Louisville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top 2 airlines flying from Louisville to Gainesville

Discover the top 2 airlines that operate flights from Louisville to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$325Average$475FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$361Average$480FlexibilityNo cancel feeOn-time71%

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