It’s generally more expensive to depart on a Monday, if you have to leave on this day you can still search on Cheapflights to find great options that meet your needs.
The best pricing can be found in the month of November. Prices to Fort Myers from Columbia, Missouri average $446. You can even find prices in November for less than $446, as users have found deals to Fort Myers from as low as $256. The month of December appears to be one of the more expensive times to travel to Fort Myers from Columbia, Missouri. Flying in the targeted month can save you up to 68%.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbia, Missouri to Fort Myers as you normally would.