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$140+ Cheap flights from Sioux Falls (FSD) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/16. Fares are subject to change and may not be available on all flights or dates of travel.
FSD — EYW
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Sioux Falls to Florida Keys

Keep the following information in mind while searching for Sioux Falls to Florida Keys flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$248
(Booking.com)

One-way from

$140
(CheapOair)

Popular in

March

Cheapest in

September

Average price

$598
Provider with most accurate pricing for Sioux Falls Joe Foss Field-Miami flight deals.
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Provider most trusted by Cheapflights users for Sioux Falls Joe Foss Field-Miami flights.
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From Sioux Falls Joe Foss Field to Florida Keys
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One-way flight from Sioux Falls Joe Foss Field to Florida Keys
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Sioux Falls to Florida Keys

Cheapest flights from Sioux Falls to Florida Keys
Explore the most affordable flight options available from Sioux Falls to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Booking.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/92:08 pmFSD - MIA
1 stop14h 14mFrontier
Mon 5/196:00 amMIA - FSD
1 stop8h 18mFrontier
Deal found 4/30$248
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/274:20 pmFSD - MIA
1 stop5h 35mDelta
Tue 6/37:25 amMIA - FSD
1 stop5h 39mDelta
Deal found 4/29$289
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/151:50 pmFSD - MIA
1 stop8h 56mUnited Airlines
Mon 5/194:08 pmMIA - FSD
1 stop7h 04mUnited Airlines
Deal found 4/30$339
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/235:16 pmFSD - MIA
1 stop6h 29mAmerican Airlines
Fri 6/276:35 amMIA - FSD
1 stop6h 01mAmerican Airlines
Deal found 4/29$344
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/199:58 amFSD - MIA
2 stops9h 14mMultiple Airlines
Fri 5/2310:49 amMIA - FSD
2 stops10h 48mMultiple Airlines
Deal found 4/29$347
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:36 amFSD - EYW
2 stops11h 51mAmerican Airlines
Wed 11/123:50 pmEYW - FSD
1 stop6h 08mAmerican Airlines
Deal found 4/29$387
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:45 amFSD - EYW
3 stops23h 15mUnited Airlines
Wed 11/126:45 pmEYW - FSD
2 stops27h 01mUnited Airlines
Deal found 4/29$476
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/155:27 amFSD - EYW
1 stop6h 29mDelta
Mon 5/196:25 pmEYW - FSD
1 stop6h 00mDelta
Deal found 4/29$714

Cheapflights Fare Finder

Customize your flight search to find flights from Sioux Falls to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Sioux Falls to Florida Keys that are best for you.

Fly from

Sioux Falls

Fly to

Florida Keys

Route

Depart

Return

Price

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Fri 5/9

2:08 pm-5:22 am

1 stop14h 14m

Miami

Mon 5/19

6:00 am-1:18 pm

1 stop8h 18m

$248

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Tue 5/27

4:20 pm-10:55 pm

1 stop5h 35m

Miami

Tue 6/3

7:25 am-12:04 pm

1 stop5h 39m

$289

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Thu 5/15

1:50 pm-11:46 pm

1 stop8h 56m

Miami

Mon 5/19

4:08 pm-10:12 pm

1 stop7h 04m

$339

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Mon 6/23

5:16 pm-12:45 am

1 stop6h 29m

Miami

Fri 6/27

6:35 am-11:36 am

1 stop6h 01m

$344

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Mon 5/19

9:58 am-8:12 pm

2 stops9h 14m

Miami

Fri 5/23

10:49 am-8:37 pm

2 stops10h 48m

$347

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Thu 5/29

8:00 am-2:00 pm

2 stops29h 00m

Key West

Mon 6/2

6:45 pm-9:52 pm

2 stops28h 07m

$483

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Fri 6/13

6:20 am-4:07 pm

1 stop8h 47m

Key West

Thu 6/19

11:20 am-9:47 pm

2 stops11h 27m

$497

Sioux FallsKey West

FSD - EYW

FSDEYW

Sioux Falls Joe Foss Field

Thu 5/15

5:27 am-12:56 pm

1 stop6h 29m

Key West

Mon 5/19

6:25 pm-11:25 pm

1 stop6h 00m

$714

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Fri 5/16

2:08 pm-5:22 am

1 stop14h 14m

$140

Sioux FallsMiami

FSD - MIA

FSDMIA

Sioux Falls Joe Foss Field

Sat 5/3

4:05 pm-11:29 pm

1 stop6h 24m

$245

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 11 results
1
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Best time to book a flight from Sioux Falls to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Sioux Falls with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Sioux Falls to Florida Keys

What is the cheapest month to book a flight from Sioux Falls to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Sioux Falls to Florida Keys (average of $328). Flying from Sioux Falls to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated May 1, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Sioux Falls to Florida Keys. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,934 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Frontier
6.0
Okay
3,287 reviews
Delta
8.0
Very good
7,934 reviews

Overall

8.0

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Sioux Falls to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Sioux Falls to Florida Keys?

    Sioux Falls Joe Foss Field (FSD), located 2.6 mi from the city center, is the airport you fly out of when you book flights from Sioux Falls to Florida Keys.

  • What are the cheapest airlines to fly from Sioux Falls to Florida Keys one-way?

    One-way options have recently been found by users for as low as $140 on Frontier. Other airlines that offer cheap prices include American Airlines from $245 and United Airlines from $777 one-way.

  • Can I find deals for flights from Sioux Falls to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Sioux Falls to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Sioux Falls to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Sioux Falls to Florida Keys.

  • Can I find deals for business class flights from Sioux Falls to Florida Keys?

    Yes. Cheapflights offers flight deals from Sioux Falls to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Sioux Falls to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Sioux Falls to Florida Keys (average of $328). Flying from Sioux Falls to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Sioux Falls to Florida Keys

Discover the top 3 airlines that operate flights from Sioux Falls to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$288Average$563FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$538FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$353Average$538FlexibilityNo cancel feeOn-time69%

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