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$60+ Cheap flights from Santa Ana, CA (SNA) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — EYW
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Santa Ana to Florida Keys

Keep the following information in mind while searching for Santa Ana to Florida Keys flight deals. Data was last updated November 3, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$146
(CheapOair)

One-way from

$60
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$474
Provider with most accurate pricing for Los Angeles-Miami flight deals.
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Provider most trusted by Cheapflights users for Los Angeles-Miami flights.
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From Santa Ana J. Wayne/Orange Cnty to Florida Keys
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One-way flight from Santa Ana J. Wayne/Orange Cnty to Florida Keys
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Highest demand for flights based on searches. 7% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Santa Ana to Florida Keys

Cheapest flights from Santa Ana to Florida Keys
Explore the most affordable flight options available from Santa Ana to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:15 amSNA - MIA
1 stop15h 04mFrontier
Wed 12/106:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/1$138
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:35 pmSNA - MIA
1 stop12h 44mFrontier
Tue 12/96:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/2$146
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:26 pmSNA - MIA
2 stops49h 28mMultiple Airlines
Wed 12/106:00 amMIA - SNA
1 stop9h 42mMultiple Airlines
Deal found 11/1$162
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:35 pmSNA - MIA
1 stop12h 44mMultiple Airlines
Sun 12/76:09 pmMIA - SNA
2 stops43h 35mMultiple Airlines
Deal found 11/1$163
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:15 amSNA - MIA
1 stop15h 04mFrontier
Tue 12/96:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/2$184
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/171:35 pmSNA - MIA
1 stop12h 44mMultiple Airlines
Tue 12/237:05 amMIA - SNA
1 stop30h 11mMultiple Airlines
Deal found 11/3$192
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:35 pmSNA - MIA
1 stop12h 44mFrontier
Sat 12/66:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/1$206
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/31:35 pmSNA - MIA
1 stop12h 44mMultiple Airlines
Sat 12/610:19 amMIA - SNA
2 stops15h 04mMultiple Airlines
Deal found 11/2$207
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2712:04 pmSNA - MIA
1 stop14h 06mFrontier
Wed 12/106:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/2$211
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:01 pmSNA - MIA
1 stop15h 18mFrontier
Sun 11/166:00 amMIA - SNA
1 stop8h 16mFrontier
Deal found 11/1$214
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:15 amSNA - MIA
1 stop15h 04mFrontier
Thu 12/116:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/3$222
This CheapOair deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/411:15 amSNA - MIA
1 stop15h 04mFrontier
Mon 12/86:00 amMIA - SNA
1 stop9h 42mFrontier
Deal found 11/2$234

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Santa Ana to Florida Keys that are best for you.

Fly from

Santa Ana

Fly to

Florida Keys

Route

Depart

Return

Price

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

5:46 pm-11:30 am

2 stops14h 44m

Miami

Mon 2/9

7:12 pm-4:51 pm

3 stops24h 39m

$293

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 11/27

12:04 pm-5:10 am

1 stop14h 06m

Miami

Fri 12/5

6:00 am-12:42 pm

1 stop9h 42m

$332

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Fri 2/27

9:10 pm-9:49 am

1 stop9h 39m

Miami

Wed 3/4

8:45 am-2:11 pm

1 stop8h 26m

$349

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Fri 4/3

12:15 pm-9:50 pm

1 stop6h 35m

Miami

Sat 4/11

7:00 am-11:17 am

1 stop7h 17m

$349

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

8:00 am-6:16 pm

1 stop7h 16m

Miami

Wed 3/4

8:45 am-5:34 pm

2 stops11h 49m

$350

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Sat 2/28

9:05 am-10:15 pm

2 stops10h 10m

Miami

Wed 3/4

12:00 pm-7:50 pm

2 stops10h 50m

$359

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

9:01 am-9:47 pm

1 stop9h 46m

Key West

Mon 2/9

1:05 pm-10:01 pm

1 stop11h 56m

$359

Santa AnaKey West

SNA - EYW

SNAEYW

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

6:45 am-11:50 pm

2 stops14h 05m

Key West

Sat 12/6

7:00 am-2:09 pm

2 stops10h 09m

$369

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Thu 12/18

6:45 am-9:04 pm

2 stops11h 19m

Miami

Wed 12/24

7:05 am-10:16 am

1 stop30h 11m

$378

Santa AnaMiami

SNA - MIA

SNAMIA

Santa Ana J. Wayne/Orange Cnty

Fri 11/28

12:04 pm-4:35 am

1 stop13h 31m

Miami

Sat 12/6

6:00 am-12:42 pm

1 stop9h 42m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 31 results
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Best time to book a flight from Santa Ana to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Florida Keys

What is the cheapest month to book a flight from Santa Ana, California to Florida Keys?

Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Florida Keys (average of $250). Flying from Santa Ana, California to Florida Keys in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated November 3, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Santa Ana to Florida Keys by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
American Airlines
7.2
Good
11,036 reviews
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Spirit Airlines
6.3
Okay
8,114 reviews
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin
Frontier
5.8
Fair
3,117 reviews
Delta
7.9
Good
8,001 reviews

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Entertainment

7.9

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to Florida Keys?

    For a flight from Santa Ana to Florida Keys, you will be flying from J. Wayne/Orange Cnty. Santa Ana J. Wayne/Orange Cnty (SNA) is just 4.8 mi from the center of the city.

  • How long is the flight from Santa Ana, California to Florida Keys?

    A quick flight from Santa Ana, California to Florida Keys can take about 9h 39m. Spirit Airlines provides one of the quickest options available for as low as $349. The distance between Santa Ana, California and Florida Keys is about 2304 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santa Ana to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Florida Keys.

  • Can I find deals for business class flights from Santa Ana to Florida Keys?

    Yes. Cheapflights offers flight deals from Santa Ana to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Florida Keys?

    Currently, September is the cheapest month in which you can book a flight from Santa Ana, California to Florida Keys (average of $250). Flying from Santa Ana, California to Florida Keys in June is currently the most expensive (average of $436). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santa Ana to Florida Keys

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Top airline flying from Santa Ana to Florida Keys

Discover the top airline that operate flights from Santa Ana to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$308Average$540FlexibilityNo cancel feeOn-time71%

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