How long is the flight from San Antonio to Florida Keys?

There are many flights that can get you from San Antonio to Florida Keys in 5h 15m. Fly via American Airlines, Delta, or Southwest to get the fastest option. San Antonio and Florida Keys are separated by a distance of 1082 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from San Antonio to Florida Keys one-way?

For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $55. Users have also found prices from $73 and $99 on Frontier and Southwest, respectively.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What are the most popular airlines that fly from San Antonio to Florida Keys?

American Airlines, Spirit Airlines and Southwest are the most popular airlines when flying from San Antonio to Florida Keys.

What is the cheapest time of day to fly from SAT to EOA?

When flying from San Antonio to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly from for flights from San Antonio to Florida Keys?

Most people fly from San Antonio (SAT) if they book a flight from San Antonio to Florida Keys. San Antonio is conveniently located just 7.6 mi from San Antonio’s city center.

Can I find deals for flights from San Antonio to Florida Keys that include hotel bookings?

Yes. In addition to deals on San Antonio to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Antonio to Florida Keys?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Florida Keys.

Can I find deals for business class flights from San Antonio to Florida Keys?

Yes. Cheapflights offers flight deals from San Antonio to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$64+ Flights from San Antonio to Florida Keys

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Cheap flight deals from San Antonio to Florida Keys

Cheapest flights from San Antonio to Florida Keys
Explore the most affordable flight options available from San Antonio to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Mon 12/222:01 pmSAT - MIA

1 stop14h 34mFrontier

Thu 1/16:05 amMIA - SAT

1 stop19h 12mFrontier

Deal found 12/16

$304

Tue 12/235:00 amSAT - MIA

Nonstop2h 56mAmerican Airlines

Tue 1/69:31 pmMIA - SAT

Nonstop3h 28mAmerican Airlines

Deal found 12/15

$341

Wed 12/245:56 pmSAT - MIA

1 stop5h 51mFrontier

Thu 1/16:05 amMIA - SAT

1 stop8h 09mFrontier

Deal found 12/17

$343

Wed 12/315:56 pmSAT - MIA

1 stop5h 51mFrontier

Fri 1/25:30 amMIA - SAT

1 stop12h 31mFrontier

Deal found 12/15

$353

Mon 12/222:01 pmSAT - MIA

1 stop14h 34mMultiple Airlines

Wed 12/318:00 amMIA - SAT

2 stops16h 26mMultiple Airlines

Deal found 12/16

$354

Mon 12/292:01 pmSAT - MIA

1 stop14h 34mFrontier

Thu 1/16:05 amMIA - SAT

1 stop30h 16mFrontier

Deal found 12/15

$362

Sat 12/202:52 pmSAT - MIA

1 stop13h 43mFrontier

Mon 12/225:30 amMIA - SAT

1 stop12h 31mFrontier

Deal found 12/15

$363

Wed 12/247:11 pmSAT - MIA

2 stops14h 47mMultiple Airlines

Wed 12/318:00 amMIA - SAT

1 stop10h 01mMultiple Airlines

Deal found 12/17

$365

Wed 12/245:56 pmSAT - MIA

1 stop5h 51mMultiple Airlines

Mon 1/510:19 pmMIA - SAT

2 stops38h 31mMultiple Airlines

Deal found 12/17

$373

Wed 12/242:09 pmSAT - MIA

1 stop13h 51mFrontier

Sat 12/276:05 amMIA - SAT

1 stop19h 12mFrontier

Deal found 12/17

$374

Mon 12/226:41 amSAT - EYW

1 stop8h 16mAmerican Airlines

Fri 12/262:50 pmEYW - SAT

1 stop9h 03mAmerican Airlines

Deal found 12/16

$401

Wed 12/315:56 pmSAT - EYW

2 stops13h 19mMultiple Airlines

Sun 1/48:55 amEYW - SAT

1 stop27h 55mMultiple Airlines

Deal found 12/16

$403

Best flights from San Antonio to Florida Keys
Discover carefully curated flight deals from San Antonio to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Sat 1/105:10 amSAT - EYW

1 stop7h 11mAmerican Airlines

Sat 1/175:15 pmEYW - SAT

1 stop5h 37mAmerican Airlines

Deal found 12/17

$204

Tue 2/2410:57 amSAT - EYW

1 stop5h 15mDelta

Wed 3/46:07 pmEYW - SAT

1 stop7h 27mDelta

Deal found 12/16

$228

Tue 1/612:15 pmSAT - MIA

1 stop5h 20mSouthwest

Wed 1/1412:00 pmMIA - SAT

1 stop8h 05mSouthwest

Deal found 12/17

$254

Thu 1/87:14 pmSAT - EYW

1 stop16h 12mMultiple Airlines

Mon 1/122:25 pmEYW - SAT

2 stops34h 27mMultiple Airlines

Deal found 12/17

$259

Sat 5/27:05 amSAT - MIA

1 stop8h 10mUnited Airlines

Mon 5/46:15 amMIA - SAT

1 stop7h 53mUnited Airlines

Deal found 12/17

$411

Sat 4/186:40 amSAT - EYW

2 stops8h 41mAmerican Airlines

Wed 4/2211:02 amEYW - SAT

1 stop10h 08mAmerican Airlines

Deal found 12/17

$242

Mon 2/2310:57 amSAT - EYW

1 stop5h 15mDelta

Tue 3/36:07 pmEYW - SAT

1 stop7h 27mDelta

Deal found 12/16

$259

Thu 1/86:30 amSAT - EYW

2 stops30h 00mMultiple Airlines

Sun 1/1110:06 amEYW - SAT

1 stop9h 12mMultiple Airlines

Deal found 12/17

$261

Sat 1/35:10 amSAT - EYW

1 stop5h 57mDelta

Wed 1/76:06 pmEYW - SAT

1 stop6h 17mDelta

Deal found 12/17

$259

Fri 1/98:10 amSAT - EYW

1 stop8h 51mAmerican Airlines

Mon 1/127:45 pmEYW - SAT

1 stop5h 14mAmerican Airlines

Deal found 12/16

$259

Sat 1/35:10 amSAT - EYW

1 stop5h 57mDelta

Fri 1/97:10 amEYW - SAT

1 stop6h 35mDelta

Deal found 12/17

$259

Fri 1/25:10 amSAT - EYW

1 stop5h 57mDelta

Wed 1/76:06 pmEYW - SAT

1 stop6h 17mDelta

Deal found 12/17

$263

Fri 1/235:10 amSAT - MIA

Nonstop2h 48mAmerican Airlines

Mon 2/26:45 pmMIA - SAT

1 stop6h 13mAmerican Airlines

Deal found 12/16

$299

Tue 3/31:45 pmSAT - MIA

2 stops7h 15mSouthwest

Thu 3/56:15 amMIA - SAT

2 stops9h 10mSouthwest

Deal found 12/14

$375

Fri 1/94:29 pmSAT - MIA

1 stop5h 19mDelta

Tue 1/136:20 pmMIA - SAT

1 stop6h 03mDelta

Deal found 12/17

$269

Sat 1/106:15 amSAT - MIA

2 stops6h 50mSouthwest

Mon 1/129:00 amMIA - SAT

2 stops9h 40mSouthwest

Deal found 12/15

$399

Fri 1/91:45 pmSAT - MIA

2 stops7h 15mSouthwest

Tue 1/136:55 amMIA - SAT

2 stops8h 35mSouthwest

Deal found 12/17

$399

Sat 1/35:10 amSAT - MIA

1 stop5h 43mDelta

Wed 1/77:15 amMIA - SAT

1 stop6h 30mDelta

Deal found 12/17

$361

Wed 4/81:00 pmSAT - MIA

1 stop9h 24mDelta

Mon 4/137:35 pmMIA - SAT

1 stop5h 39mDelta

Deal found 12/14

$411

Sat 4/252:10 pmSAT - MIA

1 stop5h 47mDelta

Fri 5/17:00 amMIA - SAT

1 stop7h 16mDelta

Deal found 12/17

$411

Thu 4/96:11 pmSAT - MIA

1 stop5h 42mDelta

Tue 4/147:00 pmMIA - SAT

1 stop6h 14mDelta

Deal found 12/16

$411

Last-minute flights from San Antonio to Florida Keys
Discover last-minute flight deals from San Antonio to Florida Keys. Data last updated December 18, 2025 and is based on user searches.

Mon 1/55:56 pmSAT - MIA

1 stop5h 55mMultiple Airlines

Wed 1/78:00 amMIA - SAT

2 stops16h 26mMultiple Airlines

Deal found 12/16

$206

Wed 1/75:10 amSAT - MIA

Nonstop2h 48mAmerican Airlines

Wed 1/212:06 pmMIA - SAT

Nonstop3h 24mAmerican Airlines

Deal found 12/15

$189

Wed 1/72:10 pmSAT - MIA

1 stop6h 20mSouthwest

Wed 1/2112:55 pmMIA - SAT

1 stop9h 15mSouthwest

Deal found 12/15

$209

Sat 1/105:10 amSAT - EYW

1 stop7h 11mAmerican Airlines

Sat 1/175:15 pmEYW - SAT

1 stop5h 37mAmerican Airlines

Deal found 12/17

$204

Sat 1/103:55 pmSAT - MIA

1 stop19h 02mFrontier

Sun 1/187:45 amMIA - SAT

2 stops32h 55mFrontier

Deal found 12/16

$207

Wed 1/146:22 pmSAT - MIA

1 stop5h 29mDelta

Wed 1/217:00 pmMIA - SAT

1 stop6h 38mDelta

Deal found 12/16

$218

Sat 1/175:10 amSAT - MIA

Nonstop2h 48mAmerican Airlines

Sat 1/249:31 pmMIA - SAT

Nonstop3h 28mAmerican Airlines

Deal found 12/17

$179

Sat 1/1712:38 pmSAT - MIA

1 stop9h 42mDelta

Sat 1/245:50 amMIA - SAT

1 stop7h 55mDelta

Deal found 12/17

$217

Mon 1/194:25 pmSAT - MIA

1 stop4h 30mSouthwest

Thu 1/2212:00 pmMIA - SAT

1 stop8h 05mSouthwest

Deal found 12/16

$199

Mon 1/196:18 pmSAT - MIA

1 stop16h 38mMultiple Airlines

Thu 1/227:00 amMIA - SAT

2 stops27h 40mMultiple Airlines

Deal found 12/16

$210

Fri 1/2310:35 amSAT - MIA

2 stops31h 55mMultiple Airlines

Mon 2/27:00 amMIA - SAT

1 stop11h 03mMultiple Airlines

Deal found 12/16

$215

Sat 1/2410:35 amSAT - MIA

2 stops13h 12mMultiple Airlines

Mon 2/27:00 amMIA - SAT

1 stop11h 03mMultiple Airlines

Deal found 12/16

$208

One-way flights from San Antonio to Florida Keys
Search for one-way flight options from San Antonio to Florida Keys. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Sat 2/217:56 pmSAT - MIA

1 stop8h 18mFrontier

Deal found 12/17

$64

Tue 2/105:12 pmSAT - MIA

1 stop11h 02mFrontier

Deal found 12/16

$68

Tue 2/175:12 pmSAT - MIA

1 stop11h 02mFrontier

Deal found 12/16

$70

Sat 2/147:56 pmSAT - MIA

1 stop8h 18mFrontier

Deal found 12/17

$74

Wed 12/315:56 pmSAT - MIA

1 stop5h 51mFrontier

Deal found 12/16

$82

Wed 2/255:12 pmSAT - MIA

1 stop11h 02mFrontier

Deal found 12/18

$85

Mon 2/28:24 pmSAT - MIA

1 stop19h 48mFrontier

Deal found 12/18

$86

Tue 1/63:55 pmSAT - MIA

2 stops21h 39mFrontier

Deal found 12/16

$90

Mon 1/266:13 pmSAT - MIA

1 stop5h 34mFrontier

Deal found 12/18

$91

Mon 1/56:40 amSAT - EYW

1 stop9h 33mUnited Airlines

Deal found 12/17

$528

Mon 1/510:08 amSAT - EYW

2 stops8h 31mAmerican Airlines

Deal found 12/17

$603

Find flight deals from San Antonio to Florida Keys

Most accurate provider	CheapOair 3 stars
Most trusted provider	CheapOair 3 stars
Round-trip from	$179 (American Airlines)
One-way from	$64 (Orbitz)
Popular in	December
Cheapest in	October
Average price	$490

Provider with most accurate pricing for San Antonio-Miami flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Antonio-Miami flights.

Search Deals

From San Antonio to Florida Keys

Search Deals

One-way flight from San Antonio to Florida Keys

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($37 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to Florida Keys that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 1/10

5:10 am-1:21 pm

1 stop7h 11m

Key West

Sat 1/17

5:15 pm-9:52 pm

1 stop5h 37m

$204

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Tue 2/24

10:57 am-5:12 pm

1 stop5h 15m

Key West

Wed 3/4

6:07 pm-12:34 am

1 stop7h 27m

$228

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 4/18

6:40 am-4:21 pm

2 stops8h 41m

Key West

Wed 4/22

11:02 am-8:10 pm

1 stop10h 08m

$242

San AntonioMiami

SAT - MIA

SATMIA

San Antonio

Tue 1/6

12:15 pm-6:35 pm

1 stop5h 20m

Miami

Wed 1/14

12:00 pm-7:05 pm

1 stop8h 05m

$254

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Thu 1/8

7:14 pm-12:26 pm

1 stop16h 12m

Key West

Mon 1/12

2:25 pm-11:52 pm

2 stops34h 27m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Mon 2/23

10:57 am-5:12 pm

1 stop5h 15m

Key West

Tue 3/3

6:07 pm-12:34 am

1 stop7h 27m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 1/3

5:10 am-12:07 pm

1 stop5h 57m

Key West

Wed 1/7

6:06 pm-11:23 pm

1 stop6h 17m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Fri 1/9

8:10 am-6:01 pm

1 stop8h 51m

Key West

Mon 1/12

7:45 pm-11:59 pm

1 stop5h 14m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Sat 1/3

5:10 am-12:07 pm

1 stop5h 57m

Key West

Fri 1/9

7:10 am-12:45 pm

1 stop6h 35m

$259

San AntonioKey West

SAT - EYW

SATEYW

San Antonio

Thu 1/8

6:30 am-1:30 pm

2 stops30h 00m

Key West

Sun 1/11

10:06 am-6:18 pm

1 stop9h 12m

$261

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 33 results

Best time to book a flight from San Antonio to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Antonio with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Florida Keys

What is the cheapest month to book a flight from San Antonio to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from San Antonio to Florida Keys (average of $191). Flying from San Antonio to Florida Keys in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Read through reviews of airlines operating flights from San Antonio to Florida Keys, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Delta

7.9

Good

8,005 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

United Airlines

7.4

Good

9,091 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

American Airlines

7.2

Good

11,054 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Spirit Airlines

6.3

Okay

8,190 reviews

Southwest

7.9

Good

4,250 reviews

Reviews

1 / 20

8.0

Excellent

Ila,Mar 2025

HOU - DAL

Our original flight was delayed. We were able to change our flight and got home at close to the same time. Looking forward to when you have assigned seating.

Related info for your journey

What airport do you fly from for flights from San Antonio to Florida Keys?
Most people fly from San Antonio (SAT) if they book a flight from San Antonio to Florida Keys. San Antonio is conveniently located just 7.6 mi from San Antonio’s city center.
How long is the flight from San Antonio to Florida Keys?
There are many flights that can get you from San Antonio to Florida Keys in 5h 15m. Fly via American Airlines, Delta, or Southwest to get the fastest option. San Antonio and Florida Keys are separated by a distance of 1082 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from San Antonio to Florida Keys one-way?
For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $55. Users have also found prices from $73 and $99 on Frontier and Southwest, respectively.
Can I find deals for flights from San Antonio to Florida Keys that include hotel bookings?
Yes. In addition to deals on San Antonio to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Antonio to Florida Keys?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Florida Keys.
Can I find deals for business class flights from San Antonio to Florida Keys?
Yes. Cheapflights offers flight deals from San Antonio to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Antonio to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from San Antonio to Florida Keys (average of $191). Flying from San Antonio to Florida Keys in March is currently the most expensive (average of $328). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

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Top 2 airlines flying from San Antonio to Florida Keys

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$227	Average$418	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$258	Average$457	FlexibilityNo cancel fee	On-time71%

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$64+ Cheap flights from San Antonio (SAT) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from San Antonio to Florida Keys

Cheapest flights from San Antonio to Florida KeysExplore the most affordable flight options available from San Antonio to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from San Antonio to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from San Antonio to Florida Keys

Keep the following information in mind while searching for San Antonio to Florida Keys flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Antonio to Florida Keys that are best for you.

Best time to book a flight from San Antonio to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Antonio with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Florida Keys

What is the cheapest month to book a flight from San Antonio to Florida Keys?

Reviews of airlines servicing Florida Keys

Read through reviews of airlines operating flights from San Antonio to Florida Keys, such as Southwest, Delta, and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from San Antonio to Florida Keys?

How long is the flight from San Antonio to Florida Keys?

What are the cheapest airlines to fly from San Antonio to Florida Keys one-way?

Can I find deals for flights from San Antonio to Florida Keys that include hotel bookings?

How can I find direct flights from San Antonio to Florida Keys?

Can I find deals for business class flights from San Antonio to Florida Keys?

What is the cheapest month to book a flight from San Antonio to Florida Keys?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from San Antonio to Florida Keys

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Cheapest flights from San Antonio to Florida Keys
Explore the most affordable flight options available from San Antonio to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.