Florida Keys

$119+ Cheap flights from Harrisburg (MDT) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — EYW
Dec 11 — Dec 181
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Cheap flight deals from Harrisburg to Florida Keys

Keep the following information in mind while searching for Harrisburg to Florida Keys flight deals. Data was last updated November 11, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$222
(American Airlines)

One-way from

$119
(Delta)

Popular in

January

Cheapest in

September

Average price

$396
Provider with most accurate pricing for Harrisburg-Miami flight deals.
Provider most trusted by Cheapflights users for Harrisburg-Miami flights.
From Harrisburg to Florida Keys
One-way flight from Harrisburg to Florida Keys
Highest demand for flights based on searches. 10% potential increase in price ($53 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Find flight deals from Harrisburg to Florida Keys

Cheapest flights from Harrisburg to Florida Keys
Explore the most affordable flight options available from Harrisburg to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 11, 2025.

This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:27 pmMDT - MIA
1 stop5h 19mDelta
Thu 12/188:10 amMIA - MDT
1 stop8h 03mDelta
Deal found 11/11$237
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/124:25 pmMDT - EYW
1 stop5h 53mAmerican Airlines
Tue 12/166:33 pmEYW - MDT
1 stop5h 17mAmerican Airlines
Deal found 11/10$259
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:25 pmMDT - MIA
1 stop7h 24mAmerican Airlines
Sat 12/138:20 amMIA - MDT
1 stop6h 04mAmerican Airlines
Deal found 11/10$259
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:40 amMDT - EYW
2 stops7h 20mAmerican Airlines
Sat 12/134:20 pmEYW - MDT
2 stops7h 59mAmerican Airlines
Deal found 11/10$269
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:00 amMDT - MIA
1 stop7h 02mDelta
Tue 12/26:00 amMIA - MDT
1 stop4h 48mDelta
Deal found 11/11$273
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/283:40 pmMDT - EYW
1 stop6h 07mAmerican Airlines
Wed 12/35:09 pmEYW - MDT
1 stop5h 08mAmerican Airlines
Deal found 11/9$284
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/283:40 pmMDT - MIA
1 stop6h 45mAmerican Airlines
Sat 12/67:10 pmMIA - MDT
1 stop5h 09mAmerican Airlines
Deal found 11/9$284
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/148:55 pmMDT - EYW
1 stop12h 06mMultiple Airlines
Mon 11/178:55 amEYW - MDT
1 stop11h 17mMultiple Airlines
Deal found 11/9$289
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/106:00 amMDT - MIA
1 stop5h 21mDelta
Wed 12/105:33 pmMIA - MDT
1 stop5h 34mDelta
Deal found 11/10$298
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:12 pmMDT - MIA
1 stop5h 34mDelta
Tue 12/26:00 amMIA - MDT
1 stop4h 48mDelta
Deal found 11/10$309
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/257:33 pmMDT - MIA
1 stop5h 13mAmerican Airlines
Tue 12/27:00 pmMIA - MDT
1 stop4h 53mAmerican Airlines
Deal found 11/9$314
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2911:08 amMDT - EYW
1 stop21h 07mMultiple Airlines
Thu 12/48:55 amEYW - MDT
1 stop25h 50mMultiple Airlines
Deal found 11/9$317

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
Use the filters below to find and compare flights from Harrisburg to Florida Keys that are best for you.

Fly from

Harrisburg

Fly to

Florida Keys

Route

Depart

Return

Price

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Mon 12/8

7:27 pm-12:46 am

1 stop5h 19m

Miami

Wed 12/10

3:50 pm-11:13 pm

1 stop7h 23m

$237

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Thu 12/4

7:27 pm-12:46 am

1 stop5h 19m

Miami

Thu 12/18

8:10 am-4:13 pm

1 stop8h 03m

$237

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Tue 12/2

7:27 pm-12:46 am

1 stop5h 19m

Miami

Wed 12/17

3:50 pm-11:13 pm

1 stop7h 23m

$237

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Fri 12/5

7:27 pm-12:46 am

1 stop5h 19m

Miami

Thu 12/18

4:55 pm-11:13 pm

1 stop6h 18m

$237

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Sat 1/10

6:30 am-3:05 pm

1 stop8h 35m

Miami

Sat 1/17

9:00 am-4:44 pm

1 stop7h 44m

$242

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 1/22

4:47 pm-9:47 pm

1 stop5h 00m

Key West

Mon 1/26

5:24 pm-10:27 pm

1 stop5h 03m

$259

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Fri 12/12

4:25 pm-10:18 pm

1 stop5h 53m

Key West

Tue 12/16

6:33 pm-11:50 pm

1 stop5h 17m

$259

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Mon 12/8

5:40 am-10:03 am

1 stop4h 23m

Miami

Mon 12/15

7:19 pm-11:50 pm

1 stop4h 31m

$259

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Thu 1/29

4:47 pm-9:47 pm

1 stop5h 00m

Key West

Mon 2/2

6:06 am-4:02 pm

2 stops9h 56m

$264

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Mon 12/8

5:40 am-1:00 pm

2 stops7h 20m

Key West

Sat 12/13

4:20 pm-12:19 am

2 stops7h 59m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 29 results
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Best time to book a flight from Harrisburg to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Florida Keys

What is the cheapest month to book a flight from Harrisburg to Florida Keys?

Currently, March is the cheapest month in which you can book a flight from Harrisburg to Florida Keys (average of $204). Flying from Harrisburg to Florida Keys in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated November 11, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Harrisburg to Florida Keys. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Harrisburg to Florida Keys?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Florida Keys. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Florida Keys?

    Airlines like Delta and American Airlines fly from Harrisburg to Florida Keys in about 5h. The time it takes to get you to your destination can typically vary by up to 19m. The distance between Harrisburg and Florida Keys is about 1118 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Harrisburg to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Florida Keys.

  • Can I find deals for business class flights from Harrisburg to Florida Keys?

    Yes. Cheapflights offers flight deals from Harrisburg to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Florida Keys?

    Currently, March is the cheapest month in which you can book a flight from Harrisburg to Florida Keys (average of $204). Flying from Harrisburg to Florida Keys in December is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Harrisburg to Florida Keys

Discover the top 2 airlines that operate flights from Harrisburg to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$454FlexibilityNo cancel feeOn-time71%
DeltaCheapest$258Average$498FlexibilityNo cancel feeOn-timeN/A

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