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$108+ Cheap flights from Harrisburg (MDT) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — EYW
Feb 7 — Feb 141
Sat 2/7
Sat 2/14
1 adult, Economy
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Cheap flight deals from Harrisburg to Florida Keys

Keep the following information in mind while searching for Harrisburg to Florida Keys flight deals. Data was last updated January 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$263
(Kiwi.com)

One-way from

$108
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$641
Provider with most accurate pricing for Harrisburg-Miami flight deals.
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Provider most trusted by Cheapflights users for Harrisburg-Miami flights.
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From Harrisburg to Florida Keys
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One-way flight from Harrisburg to Florida Keys
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Highest demand for flights based on searches. 9% potential increase in price ($50 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Harrisburg to Florida Keys

Cheapest flights from Harrisburg to Florida Keys
Explore the most affordable flight options available from Harrisburg to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:49 pmMDT - EYW
1 stop15h 32mMultiple Airlines
Mon 2/231:06 pmEYW - MDT
1 stop21h 26mMultiple Airlines
Deal found 1/6$263
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/216:04 pmMDT - EYW
1 stop27h 33mMultiple Airlines
Sun 1/2510:06 amEYW - MDT
1 stop8h 49mMultiple Airlines
Deal found 1/6$270
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/34:47 pmMDT - EYW
1 stop5h 00mAmerican Airlines
Tue 2/106:43 pmEYW - MDT
1 stop4h 54mAmerican Airlines
Deal found 1/7$279
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:15 amMDT - MIA
1 stop5h 01mUnited Airlines
Tue 2/101:45 pmMIA - MDT
1 stop5h 14mUnited Airlines
Deal found 1/6$279
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:11 pmMDT - EYW
1 stop16h 10mMultiple Airlines
Fri 2/279:49 amEYW - MDT
1 stop9h 26mMultiple Airlines
Deal found 1/6$286
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/168:49 pmMDT - EYW
1 stop15h 32mMultiple Airlines
Tue 2/241:01 pmEYW - MDT
1 stop27h 52mMultiple Airlines
Deal found 1/6$287
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/76:00 amMDT - MIA
Nonstop3h 08mAmerican Airlines
Tue 2/104:03 pmMIA - MDT
1 stop7h 34mAmerican Airlines
Deal found 1/6$289
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/263:10 pmMDT - MIA
1 stop7h 05mUnited Airlines
Sat 1/319:00 amMIA - MDT
1 stop7h 44mUnited Airlines
Deal found 1/6$294
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/314:49 pmMDT - MIA
1 stop5h 33mAmerican Airlines
Tue 2/36:45 pmMIA - MDT
1 stop4h 52mAmerican Airlines
Deal found 1/6$299
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/166:30 amMDT - MIA
1 stop8h 27mUnited Airlines
Wed 5/206:00 pmMIA - MDT
1 stop5h 27mUnited Airlines
Deal found 1/6$305
This Delta deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/236:02 pmMDT - MIA
1 stop6h 49mDelta
Tue 1/275:50 amMIA - MDT
1 stop5h 47mDelta
Deal found 1/8$309
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/163:33 pmMDT - EYW
1 stop7h 04mAmerican Airlines
Tue 2/241:55 pmEYW - MDT
2 stops9h 28mAmerican Airlines
Deal found 1/6$314

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
Use the filters below to find and compare flights from Harrisburg to Florida Keys that are best for you.

Fly from

Harrisburg

Fly to

Florida Keys

Route

Depart

Return

Price

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Mon 2/16

8:49 pm-12:21 pm

1 stop15h 32m

Key West

Mon 2/23

1:06 pm-10:32 am

1 stop21h 26m

$263

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Wed 1/21

6:04 pm-9:37 pm

1 stop27h 33m

Key West

Sun 1/25

10:06 am-6:55 pm

1 stop8h 49m

$270

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Wed 4/8

3:37 pm-10:36 pm

1 stop6h 59m

Key West

Wed 4/15

8:05 am-2:52 pm

1 stop6h 47m

$279

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Tue 3/3

6:15 am-11:16 am

1 stop5h 01m

Miami

Tue 3/10

12:11 pm-9:05 pm

1 stop8h 54m

$279

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Wed 2/25

12:08 pm-6:20 pm

1 stop6h 12m

Miami

Tue 3/3

6:00 am-11:10 am

1 stop5h 10m

$279

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Sat 2/21

3:33 pm-10:37 pm

1 stop7h 04m

Key West

Wed 2/25

5:04 pm-10:14 pm

1 stop5h 10m

$279

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Tue 2/3

6:15 am-11:16 am

1 stop5h 01m

Miami

Tue 2/10

1:45 pm-6:59 pm

1 stop5h 14m

$279

HarrisburgKey West

MDT - EYW

MDTEYW

Harrisburg

Tue 2/17

9:51 am-7:15 pm

2 stops9h 24m

Key West

Tue 2/24

1:55 pm-11:23 pm

2 stops9h 28m

$290

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Sun 1/25

6:02 pm-12:51 am

1 stop6h 49m

Miami

Sat 1/31

7:15 am-1:16 pm

1 stop6h 01m

$294

HarrisburgMiami

MDT - MIA

MDTMIA

Harrisburg

Wed 1/21

6:02 pm-12:51 am

1 stop6h 49m

Miami

Wed 1/28

5:50 am-11:37 am

1 stop5h 47m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/8

Showing 1-10 of 35 results
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Best time to book a flight from Harrisburg to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Florida Keys

What is the cheapest month to book a flight from Harrisburg to Florida Keys?

Currently, March is the cheapest month in which you can book a flight from Harrisburg to Florida Keys (average of $201). Flying from Harrisburg to Florida Keys in February is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated January 8, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Harrisburg to Florida Keys. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,025 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,025 reviews
Delta
7.9
Good
8,025 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
9,139 reviews
Delta
7.9
Good
8,025 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,094 reviews
Delta
7.9
Good
8,025 reviews

Comfort

7.9

Crew

8.5

Entertainment

7.8

Boarding

8.1

Food

7.2

Overall

7.9

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Florida Keys?

    Harrisburg (MDT) is the airport you will fly out of if you book a flight from Harrisburg to Florida Keys. It is only a 8.5 mi journey to Harrisburg (MDT) from Harrisburg’s city center.

  • How long is the flight from Harrisburg to Florida Keys?

    Airlines like American Airlines, United Airlines, and Delta fly from Harrisburg to Florida Keys in about 5h 01m. The time it takes to get you to your destination can typically vary by up to 1h 58m. The distance between Harrisburg and Florida Keys is about 1015 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Harrisburg to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Florida Keys.

  • Can I find deals for business class flights from Harrisburg to Florida Keys?

    Yes. Cheapflights offers flight deals from Harrisburg to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Florida Keys?

    Currently, March is the cheapest month in which you can book a flight from Harrisburg to Florida Keys (average of $201). Flying from Harrisburg to Florida Keys in February is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Harrisburg to Florida Keys

Discover the top 2 airlines that operate flights from Harrisburg to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$258Average$408FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$273Average$447FlexibilityNo cancel feeOn-time71%

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