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$100+ Cheap flights from Columbia (CAE) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
CAE — EYW
Mar 16 — Mar 231
Mon 3/16
Mon 3/23
1 adult, Economy
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Cheap flight deals from Columbia to Florida Keys

Cheapest flights from Columbia to Florida Keys
Explore the most affordable flight options available from Columbia to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 14, 2026.

This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/164:12 pm
CAE
-
MIA
1 stop6h 39m
American Airlines
Sat 5/239:45 pm
MIA
-
CAE
Nonstop2h 14m
American Airlines
Deal found 2/12$250
This American Airlines deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:43 pm
CAE
-
MIA
1 stop6h 04m
American Airlines
Sat 5/97:45 am
MIA
-
CAE
1 stop4h 35m
American Airlines
Deal found 2/12$251
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:13 pm
CAE
-
MIA
1 stop5h 39m
Delta
Wed 3/257:05 am
MIA
-
CAE
1 stop6h 22m
Delta
Deal found 2/13$260
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:40 am
CAE
-
MIA
1 stop3h 47m
Delta
Thu 6/47:00 am
MIA
-
CAE
1 stop6h 04m
Delta
Deal found 2/12$269
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:07 pm
CAE
-
MIA
1 stop5h 40m
Delta
Fri 3/67:15 am
MIA
-
CAE
1 stop4h 45m
Delta
Deal found 2/13$274
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:40 am
CAE
-
MIA
1 stop3h 42m
Delta
Fri 7/37:00 am
MIA
-
CAE
1 stop5h 28m
Delta
Deal found 2/11$279
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:35 am
CAE
-
MIA
1 stop3h 51m
Delta
Thu 3/127:05 am
MIA
-
CAE
1 stop6h 22m
Delta
Deal found 2/10$284
This Delta deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:28 am
CAE
-
MIA
1 stop7h 09m
Delta
Tue 3/174:44 pm
MIA
-
CAE
1 stop7h 04m
Delta
Deal found 2/12$285
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 pm
CAE
-
MIA
1 stop4h 48m
American Airlines
Sun 11/226:00 am
MIA
-
CAE
1 stop4h 39m
American Airlines
Deal found 2/11$289
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:16 pm
CAE
-
MIA
1 stop4h 54m
Delta
Sun 5/107:00 am
MIA
-
CAE
1 stop4h 08m
Delta
Deal found 2/11$290
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/253:09 pm
CAE
-
EYW
1 stop4h 33m
Delta
Wed 3/47:10 am
EYW
-
CAE
1 stop4h 50m
Delta
Deal found 2/11$309
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/283:32 pm
CAE
-
EYW
1 stop6h 37m
United Airlines
Wed 3/46:35 pm
EYW
-
CAE
1 stop5h 09m
United Airlines
Deal found 2/13$349

Find flight deals from Columbia to Florida Keys

Keep the following information in mind while searching for Columbia to Florida Keys flight deals. Data was last updated February 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$251
(American Airlines)

One-way from

$100
(Kiwi.com)

Popular in

February

Cheapest in

August

Average price

$536
Provider with most accurate pricing for Columbia Metropolitan-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Metropolitan-Miami flights.
Search Deals
From Columbia Metropolitan to Florida Keys
Search Deals
One-way flight from Columbia Metropolitan to Florida Keys
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
Use the filters below to find and compare flights from Columbia to Florida Keys that are best for you.

Fly from

Columbia

Fly to

Florida Keys

Route

Depart

Return

Price

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Mon 4/27

6:20 pm-10:51 pm

1 stop4h 31m

Miami

Sat 5/2

7:45 am-12:20 pm

1 stop4h 35m

$260

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Wed 5/20

5:40 am-10:53 am

1 stop5h 13m

Miami

Wed 5/27

6:00 am-1:04 pm

1 stop7h 04m

$260

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Mon 8/3

6:50 pm-12:56 am

1 stop6h 06m

Miami

Mon 8/10

6:00 am-11:17 am

1 stop5h 17m

$269

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sun 5/17

5:50 pm-12:55 am

1 stop7h 05m

Miami

Sun 5/24

6:00 am-1:04 pm

1 stop7h 04m

$269

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 5/28

5:40 am-9:27 am

1 stop3h 47m

Miami

Thu 6/4

6:00 am-1:04 pm

1 stop7h 04m

$269

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 4/16

7:14 pm-12:54 am

1 stop5h 40m

Miami

Thu 4/23

6:00 am-11:29 am

1 stop5h 29m

$269

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sat 2/28

5:35 am-9:26 am

1 stop3h 51m

Miami

Thu 3/12

7:05 am-1:27 pm

1 stop6h 22m

$284

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Sat 5/2

12:16 pm-5:10 pm

1 stop4h 54m

Miami

Sun 5/10

7:00 am-11:08 am

1 stop4h 08m

$290

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Thu 4/9

7:13 pm-12:52 am

1 stop5h 39m

Miami

Thu 4/16

8:05 am-1:14 pm

1 stop5h 09m

$294

ColumbiaMiami

CAE - MIA

CAEMIA

Columbia Metropolitan

Mon 3/16

4:28 pm-10:26 pm

1 stop5h 58m

Miami

Wed 3/25

7:05 am-1:27 pm

1 stop6h 22m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/14

Showing 1-10 of 29 results
1
2
3

Best time to book a flight from Columbia to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Florida Keys

What is the cheapest month to book a flight from Columbia to Florida Keys?

Currently, March is the cheapest month in which you can book a flight from Columbia to Florida Keys (average of $133). Flying from Columbia to Florida Keys in April is currently the most expensive (average of $439). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated February 14, 2026.
Read reviews from past customers who have flown Delta and American Airlines from Columbia to Florida Keys. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,203 reviews

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,203 reviews
Delta
7.9
Good
8,203 reviews

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,288 reviews
Delta
7.9
Good
8,203 reviews

Food

7.2

Crew

8.5

Boarding

8.1

Overall

7.9

Entertainment

7.8

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Florida Keys?

    Columbia Metropolitan (CAE) is the airport you will fly out of if you book a flight from Columbia to Florida Keys. It is only a 6.5 mi journey to Metropolitan (CAE) from Columbia’s city center.

  • How long is the flight from Columbia to Florida Keys?

    There are many flights that can get you from Columbia to Florida Keys in 5h 39m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. The distance from Columbia to Florida Keys is about 565 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Columbia to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Columbia to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Florida Keys.

  • Can I find deals for business class flights from Columbia to Florida Keys?

    Yes. Cheapflights offers flight deals from Columbia to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbia to Florida Keys?

    Currently, March is the cheapest month in which you can book a flight from Columbia to Florida Keys (average of $133). Flying from Columbia to Florida Keys in April is currently the most expensive (average of $439). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Columbia to Florida Keys

Discover the top 2 airlines that operate flights from Columbia to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$538FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$353Average$554FlexibilityNo cancel feeOn-time71%

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