Florence

$480+ Cheap flights from Iowa to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/3. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Jan 22 — Jan 291
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Cheap flight deals from Iowa to Florence

Cheapest flights from Iowa to Florence
Explore the most affordable flight options available from Iowa to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This KAYAK deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops40h 44mLufthansa
Thu 1/11:15 pmFLR - DSM
2 stops35h 50mLufthansa
Deal found 12/22$1,553

Find flight deals from Iowa to Florence

Keep the following information in mind while searching for Iowa to Florence flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$469
(Ticket)

Popular in

June

Cheapest in

October

Average price

$1,472
Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.
Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.
From Iowa to Florence Peretola
Highest demand for flights based on searches. 16% potential increase in price ($247 potential increase over avg. RT price).
Cheapest flight prices on average. 4% potential price decrease ($49 potential savings vs. average RT price).
Average for round-trip flights in December 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Iowa to Florence that are best for you.

Fly from

Iowa

Fly to

Florence

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 2/3

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

Thu 2/12

6:30 am-9:41 pm

2 stops22h 11m

$480

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 2/6

10:21 am-11:40 am

2 stops18h 19m

Florence Peretola

Fri 2/13

6:40 am-8:49 pm

2 stops21h 09m

$485

OmahaFlorence

OMA - FLR

OMAFLR

Omaha Eppley Airfield

Fri 2/6

1:42 pm-11:45 am

2 stops39h 03m

Florence Peretola

Fri 2/13

12:45 pm-10:42 pm

2 stops16h 57m

$489

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 2/6

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

Fri 2/13

6:30 am-9:41 pm

2 stops22h 11m

$491

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 2/16

5:15 pm-7:50 pm

2 stops19h 35m

Florence Peretola

Thu 2/26

6:40 am-10:17 am

2 stops34h 37m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 2/21

6:19 am-2:25 pm

2 stops25h 06m

Florence Peretola

Sat 2/28

6:40 am-10:17 am

2 stops34h 37m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 2/20

5:43 pm-2:25 pm

2 stops37h 42m

Florence Peretola

Sat 2/28

6:40 am-10:17 am

2 stops34h 37m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 2/22

10:40 am-2:25 pm

2 stops20h 45m

Florence Peretola

Sun 3/1

6:40 am-10:17 am

2 stops34h 37m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 2/17

5:24 am-7:50 pm

2 stops31h 26m

Florence Peretola

Mon 2/23

12:20 pm-9:20 pm

2 stops40h 00m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 2/16

11:46 am-7:50 pm

2 stops25h 04m

Florence Peretola

Tue 2/24

12:15 pm-3:40 pm

2 stops34h 25m

$499

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 26 results
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Best time to book a flight from Iowa to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Florence
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Florence from Iowa?

    If you book a flight to Florence from Iowa, you will be flying to Peretola, which is the city’s only airport. Florence Peretola (FLR) is located 3.7 mi from the center of Florence.

  • How long is the flight from Iowa to Florence?

    A quick flight from Iowa to Florence can take about 18h 05m. Lufthansa provides one of the quickest options available for as low as $480. Iowa and Florence are separated by a distance of 4923 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Iowa to Florence that include hotel bookings?

    Yes. In addition to deals on Iowa to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Florence.

  • Can I find deals for business class flights from Iowa to Florence?

    Yes. Cheapflights offers flight deals from Iowa to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia

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Alternative routes for Iowa to Florence

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Iowa to Florence

Discover the top 2 airlines that operate flights from Iowa to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$660Average$1,668FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$790Average$1,242FlexibilityNo cancel feeOn-time69%

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