HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$699+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Des Moines to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Des Moines to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$699
(lastminute.com)

Popular in

June

Cheapest in

October

Average price

$1,372
Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.
Search Deals
From Des Moines to Florence Peretola
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($234 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($43 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Flysmarter deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:35 amDSM - FLR
2 stops19h 05mLufthansa
Tue 1/69:35 amFLR - DSM
3 stops32h 20mLufthansa
Deal found 11/15$811
This United Airlines deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/303:14 pmDSM - FLR
2 stops15h 26mUnited Airlines
Tue 1/69:35 amFLR - DSM
2 stops19h 15mUnited Airlines
Deal found 11/15$856
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops36h 04mUnited Airlines
Thu 1/19:45 amFLR - DSM
2 stops32h 05mUnited Airlines
Deal found 11/16$1,427
This Ovago deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops40h 44mLufthansa
Thu 1/11:15 pmFLR - DSM
2 stops39h 25mLufthansa
Deal found 11/15$1,537

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Des Moines

Fly to

Florence

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/1

6:46 pm-4:30 pm

2 stops14h 44m

Florence Peretola

Thu 1/8

2:15 pm-9:50 pm

2 stops38h 35m

$699

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/15

11:30 am-4:30 pm

2 stops22h 00m

Florence Peretola

Tue 5/12

6:40 am-9:36 pm

2 stops21h 56m

$723

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/1

6:46 pm-4:30 pm

2 stops14h 44m

Florence Peretola

Thu 1/8

2:15 pm-9:50 pm

2 stops38h 35m

$727

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 1/1

3:14 pm-4:30 pm

2 stops18h 16m

Florence Peretola

Thu 1/8

6:35 am-9:50 pm

2 stops22h 15m

$790

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 12/30

11:35 am-1:40 pm

2 stops19h 05m

Florence Peretola

Tue 1/6

9:35 am-10:55 am

3 stops32h 20m

$811

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 12/30

3:14 pm-1:40 pm

2 stops15h 26m

Florence Peretola

Tue 1/6

9:35 am-9:50 pm

2 stops19h 15m

$856

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Compare providers for flights from Des Moines to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated November 17, 2025.
See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,014 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,576 reviews
Delta
7.9
Good
8,007 reviews

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Florence?

    Airlines like Lufthansa and United Airlines fly from Des Moines to Florence in about 18h 16m. The time it takes to get you to your destination can typically vary by up to 3h 44m. Des Moines and Florence are separated by a distance of 4923 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Florence round-trip?

    Flying on Delta is currently your cheapest option to Florence, with prices starting at $660. Additional round-trip tickets that might be worth considering are offered by United Airlines and Lufthansa, with the lowest prices starting at $790 and $811, respectively. Delta is priced at 46% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Florence that include hotel bookings?

    Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

  • Can I find deals for business class flights from Des Moines to Florence?

    Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Des Moines to Florence

Discover the top 3 airlines that operate flights from Des Moines to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$660Average$1,541FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$790Average$1,242FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$811Average$1,367FlexibilityNo cancel feeOn-time76%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.