What are the cheapest airlines flying from Des Moines to Florence round-trip?

Flying on United Airlines is currently your cheapest option to Florence, with prices starting at $667. Additional round-trip tickets that might be worth considering are offered by Lufthansa and Air France, with the lowest prices starting at $669 and $721, respectively.

What is the cheapest month to book a flight from Des Moines to Florence?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Florence (average of $766). Flying from Des Moines to Florence in June is currently the most expensive (average of $1,299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest day to fly from Des Moines to Florence?

Travelers seeking maximum savings on their Des Moines to Florence flight should consider departing on Wednesday afternoons when fares are most often at their lowest. Thursday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Florence ranges from 1.2 - 3.9 inches per month. October is typically the wettest month, when rainfall can reach 3.9 in. July is typically the driest time to visit Florence when rainfall is around 1.2 in.

If weather is an important factor for your trip to Florence, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular airlines that fly from Des Moines to Florence?

When booking a flight from Des Moines to Florence, you may want to consider flying on Delta, Lufthansa or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Florence?

Wednesday flights are generally found to be more expensive for flights from Des Moines to Florence. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Florence.

What is the cheapest time of day to fly from DSM to FLR?

It’s optimal to fly from Des Moines to Florence at noon. By choosing this option you can save up to 31% on the cost of your flight, compared to a flight in the morning.

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

Can I find deals for business class flights from Des Moines to Florence?

Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$496+ Flights from Des Moines to Florence

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Cheap flight deals from Des Moines to Florence

Round-trip from	$667 (United Airlines)
One-way from	$496 (Kiwi.com)

From Des Moines to Florence Peretola

Search Deals

One-way flight from Des Moines to Florence Peretola

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Find flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 1, 2025.

ven. 11/143:15 pmDSM - FLR

2 stops15h 50mUnited Airlines

mar. 11/186:30 amFLR - DSM

2 stops17h 55mUnited Airlines

Deal found 6/29

$667

ven. 11/146:50 pmDSM - FLR

2 stops14h 45mLufthansa

mar. 11/186:30 amFLR - DSM

2 stops17h 55mLufthansa

Deal found 6/30

$669

mer. 8/1311:23 amDSM - FLR

2 stops17h 37mAir France

mer. 8/206:25 amFLR - DSM

2 stops18h 20mAir France

Deal found 6/29

$721

mer. 8/1311:23 amDSM - FLR

2 stops20h 02mDelta

mer. 8/206:25 amFLR - DSM

2 stops18h 20mDelta

Deal found 6/30

$776

jeu. 8/1411:25 amDSM - FLR

2 stops19h 40mMultiple Airlines

jeu. 8/216:40 amFLR - DSM

2 stops17h 34mMultiple Airlines

Deal found 6/30

$809

ven. 8/1511:23 amDSM - FLR

2 stops14h 37mKLM

ven. 8/227:00 amFLR - DSM

2 stops16h 45mKLM

Deal found 7/1

$845

mer. 8/138:00 amDSM - FLR

3 stops18h 40mAir Canada

mer. 8/206:40 amFLR - DSM

3 stops22h 05mAir Canada

Deal found 6/29

$1,003

Best flights from Des Moines to Florence
Discover carefully curated flight deals from Des Moines to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated juillet 1, 2025.

ven. 11/143:15 pmDSM - FLR

2 stops15h 50mUnited Airlines

mar. 11/186:30 amFLR - DSM

2 stops17h 55mUnited Airlines

Deal found 6/29

$667

ven. 11/146:50 pmDSM - FLR

2 stops14h 45mLufthansa

mar. 11/186:30 amFLR - DSM

2 stops17h 55mLufthansa

Deal found 6/30

$669

mer. 8/1311:23 amDSM - FLR

2 stops17h 37mAir France

mer. 8/206:25 amFLR - DSM

2 stops18h 20mAir France

Deal found 6/29

$721

mer. 8/1311:23 amDSM - FLR

2 stops20h 02mDelta

mer. 8/206:25 amFLR - DSM

2 stops18h 20mDelta

Deal found 6/30

$776

jeu. 8/1411:25 amDSM - FLR

2 stops19h 40mMultiple Airlines

jeu. 8/216:40 amFLR - DSM

2 stops17h 34mMultiple Airlines

Deal found 6/30

$809

ven. 8/1511:23 amDSM - FLR

2 stops14h 37mKLM

ven. 8/227:00 amFLR - DSM

2 stops16h 45mKLM

Deal found 7/1

$845

mer. 8/138:00 amDSM - FLR

3 stops18h 40mAir Canada

mer. 8/206:40 amFLR - DSM

3 stops22h 05mAir Canada

Deal found 6/29

$1,003

One-way flights from Des Moines to Florence
Search for one-way flight options from Des Moines to Florence. Find affordable one-way fares based on user searches. Data last updated juillet 1, 2025.

jeu. 10/1610:41 amDSM - FLR

3 stops53h 24mMultiple Airlines

Deal found 6/30

$496

jeu. 10/166:07 pmDSM - FLR

2 stops34h 23mBritish Airways

Deal found 6/30

$535

jeu. 8/1411:25 amDSM - FLR

3 stops18h 35mAir Canada

Deal found 6/29

$890

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

ven. 11/14

3:15 pm-2:05 pm

2 stops15h 50m

Florence Peretola

mar. 11/18

6:30 am-5:25 pm

2 stops17h 55m

$667

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

ven. 11/14

6:50 pm-4:35 pm

2 stops14h 45m

Florence Peretola

mar. 11/18

6:30 am-5:25 pm

2 stops17h 55m

$669

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mer. 8/13

11:23 am-12:00 pm

2 stops17h 37m

Florence Peretola

mer. 8/20

6:25 am-5:45 pm

2 stops18h 20m

$721

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mer. 8/13

11:23 am-2:25 pm

2 stops20h 02m

Florence Peretola

mer. 8/20

6:25 am-5:45 pm

2 stops18h 20m

$776

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jeu. 8/14

11:25 am-2:05 pm

2 stops19h 40m

Florence Peretola

jeu. 8/21

6:40 am-5:14 pm

2 stops17h 34m

$809

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

ven. 8/15

11:23 am-9:00 am

2 stops14h 37m

Florence Peretola

ven. 8/22

7:00 am-4:45 pm

2 stops16h 45m

$845

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mer. 8/13

8:00 am-9:40 am

3 stops18h 40m

Florence Peretola

mer. 8/20

6:40 am-9:45 pm

3 stops22h 05m

$1,003

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jeu. 10/16

10:41 am-11:05 pm

3 stops53h 24m

$496

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jeu. 10/16

6:07 pm-11:30 am

2 stops34h 23m

$535

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jeu. 8/14

11:25 am-1:00 pm

3 stops18h 35m

$890

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, KLM, and Air France from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,973 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

KLM

7.8

Good

1,366 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Air France

7.5

Good

1,472 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,858 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Air Canada

7.1

Good

9,665 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Des Moines to Florence round-trip?
Flying on United Airlines is currently your cheapest option to Florence, with prices starting at $667. Additional round-trip tickets that might be worth considering are offered by Lufthansa and Air France, with the lowest prices starting at $669 and $721, respectively.
Can I find deals for flights from Des Moines to Florence that include hotel bookings?
Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.
Can I find deals for business class flights from Des Moines to Florence?
Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Florence?
Currently, November is the cheapest month in which you can book a flight from Des Moines to Florence (average of $766). Flying from Des Moines to Florence in June is currently the most expensive (average of $1,299). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Prato

Fiesole

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Top 3 airlines flying from Des Moines to Florence

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$790	Average$1,186	FlexibilityNo cancel fee	On-time69%
Lufthansa	Cheapest$811	Average$1,372	FlexibilityNo cancel fee	On-time76%
Delta	Cheapest$955	Average$1,517	FlexibilityNo cancel fee	On-timeN/A

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$496+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Florence with Cheapflights

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Cheap flight deals from Des Moines to Florence

Round-trip from

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Find flight deals from Des Moines to Florence

Cheapest flights from Des Moines to FlorenceExplore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 1, 2025.

Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, KLM, and Air France from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Des Moines to Florence round-trip?

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

How can I find direct flights from Des Moines to Florence?

Can I find deals for business class flights from Des Moines to Florence?

What is the cheapest month to book a flight from Des Moines to Florence?

Traveling to a place near Des Moines?

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Alternative routes for Des Moines to Florence

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Top 3 airlines flying from Des Moines to Florence

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Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on juillet 1, 2025.