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$411+ Cheap flights from Tampa to Florence, SC (TPA - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — FLO
Aug 24 — Aug 311
Sun 8/24
Sun 8/31
1 adult, Economy
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Cheap flight deals from Tampa to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 19, 2025.

Round-trip from

$411
(American Airlines)
From Tampa to Florence
Search Deals

Find flight deals from Tampa to Florence

Cheapest flights from Tampa to Florence
Explore the most affordable flight options available from Tampa to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 19, 2025.

This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:03 amTPA - FLO
1 stop4h 43mAmerican Airlines
Sun 10/265:14 amFLO - TPA
1 stop6h 04mAmerican Airlines
Deal found 8/19$411
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/31:06 pmTPA - FLO
2 stops10h 10mAmerican Airlines
Wed 10/156:14 amFLO - TPA
2 stops8h 34mAmerican Airlines
Deal found 8/16$421
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:19 amTPA - FLO
1 stop5h 35mAmerican Airlines
Sun 10/265:14 amFLO - TPA
1 stop6h 04mAmerican Airlines
Deal found 8/19$435
This American Airlines deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2011:02 amTPA - FLO
1 stop4h 02mAmerican Airlines
Sat 8/2311:15 amFLO - TPA
1 stop3h 27mAmerican Airlines
Deal found 8/16$467
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/245:11 pmTPA - FLO
1 stop6h 48mAmerican Airlines
Wed 8/273:30 pmFLO - TPA
1 stop5h 53mAmerican Airlines
Deal found 8/18$708

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
Use the filters below to find and compare flights from Tampa to Florence that are best for you.

Fly from

Tampa

Fly to

Florence

Route

Depart

Return

Price

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 10/3

6:00 am-12:02 pm

1 stop6h 02m

Florence

Wed 10/15

3:19 pm-7:42 pm

1 stop4h 23m

$411

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Sat 10/25

1:45 pm-7:10 pm

1 stop5h 25m

Florence

Sun 10/26

5:14 am-9:20 am

1 stop4h 06m

$411

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 10/24

9:19 am-2:54 pm

1 stop5h 35m

Florence

Sun 10/26

5:14 am-9:20 am

1 stop4h 06m

$435

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 10/24

11:08 am-2:54 pm

1 stop3h 46m

Florence

Mon 10/27

2:29 pm-8:19 pm

1 stop5h 50m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Tampa to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Florence

What is the cheapest month to book a flight from Tampa to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Tampa to Florence, South Carolina (average of $366). Flying from Tampa to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated August 19, 2025.
Get a feel of what it's like to fly with American Airlines from Tampa to Florence by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Food

6.5

Overall

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Food

6.5

Overall

7.2

Boarding

7.5

Crew

8.0

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tampa to Florence, South Carolina?

    Airlines like American Airlines fly from Tampa to Florence, South Carolina in about 6h 02m. The time it takes to get you to your destination can typically vary by up to . There are 460 mi between Tampa and Florence, South Carolina.

  • What is the cheapest airline to fly from Tampa to Florence, South Carolina round-trip?

    Flying on American Airlines is currently your cheapest option to Florence, South Carolina, with prices starting at $315.

  • Can I find deals for flights from Tampa to Florence that include hotel bookings?

    Yes. In addition to deals on Tampa to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Florence.

  • Can I find deals for business class flights from Tampa to Florence?

    Yes. Cheapflights offers flight deals from Tampa to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Tampa to Florence, South Carolina (average of $366). Flying from Tampa to Florence, South Carolina in October is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Tampa to Florence

Discover the top airline that operate flights from Tampa to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$315Average$441FlexibilityNo cancel feeOn-time71%

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