HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$437+ Cheap flights from San Francisco Bay Area to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/4. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — FLO
Mar 9 — Mar 161
Mon 3/9
Mon 3/16
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Francisco Bay Area to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Francisco Bay Area to Florence

Cheapest flights from San Francisco Bay Area to Florence
Explore the most affordable flight options available from San Francisco Bay Area to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.

This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/412:31 pm
SFO
-
FLO
1 stop7h 37m
American Airlines
Wed 3/116:20 pm
FLO
-
SFO
1 stop7h 50m
American Airlines
Deal found 2/4$437
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:00 am
SFO
-
FLO
1 stop7h 50m
American Airlines
Tue 2/246:15 am
FLO
-
SFO
1 stop10h 45m
American Airlines
Deal found 2/4$557
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:00 am
SJC
-
FLO
2 stops14h 08m
American Airlines
Fri 2/205:16 am
FLO
-
SJC
2 stops11h 01m
American Airlines
Deal found 2/4$1,143

Find flight deals from San Francisco Bay Area to Florence

Keep the following information in mind while searching for San Francisco Bay Area to Florence flight deals. Data was last updated February 7, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$437
(American Airlines)
Provider with most accurate pricing for San Francisco-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Florence flights.
Search Deals
From San Francisco Bay Area to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco Bay Area to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from San Francisco Bay Area to Florence that are best for you.

Fly from

San Francisco Bay Area

Fly to

Florence

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Wed 3/4

12:31 pm-11:08 pm

1 stop7h 37m

Florence

Wed 3/11

6:20 pm-11:10 pm

1 stop7h 50m

$437

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Fri 2/20

7:00 am-5:50 pm

1 stop7h 50m

Florence

Tue 2/24

6:15 am-2:00 pm

1 stop10h 45m

$557

San JoseFlorence

SJC - FLO

SJCFLO

San Jose

Tue 2/17

6:00 am-11:08 pm

2 stops14h 08m

Florence

Fri 2/20

5:16 am-1:17 pm

2 stops11h 01m

$1,143

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Best time to book a flight from San Francisco Bay Area to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from San Francisco Bay Area with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco Bay Area to Florence

What is the cheapest month to book a flight from San Francisco Bay Area to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Florence, South Carolina (average of $148). Flying from San Francisco Bay Area to Florence, South Carolina in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from San Francisco Bay Area to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from San Francisco Bay Area?

    For a flight from San Francisco Bay Area to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from San Francisco Bay Area to Florence, South Carolina?

    There are many flights that can get you from San Francisco Bay Area to Florence, South Carolina in 7h 37m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 2377 mi.

  • What are the most popular routes from San Francisco Bay Area to Florence, South Carolina?

    When deciding which route to take from San Francisco Bay Area to Florence, South Carolina consider San Francisco - Florence, Oakland - Florence or San Jose - Florence as they are the most popular.

  • Can I find deals for flights from San Francisco Bay Area to Florence that include hotel bookings?

    Yes. In addition to deals on San Francisco Bay Area to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco Bay Area to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco Bay Area to Florence.

  • Can I find deals for business class flights from San Francisco Bay Area to Florence?

    Yes. Cheapflights offers flight deals from San Francisco Bay Area to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco Bay Area to Florence, South Carolina?

    Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Florence, South Carolina (average of $148). Flying from San Francisco Bay Area to Florence, South Carolina in March is currently the most expensive (average of $239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Francisco Bay Area to Florence

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Charlotte flights
San Francisco to Charlotte flights
Ontario to Charlotte flights
Los Angeles to Charleston flights
San Francisco to Savannah flights
Santa Ana to Charlotte flights
San Diego to Charlotte flights
Burbank to Charlotte flights
Ontario to Charleston flights
San Francisco to Charleston flights
San Diego to Charleston flights
Los Angeles to Savannah flights
Sacramento to Charleston flights
Sacramento to Charlotte flights
Los Angeles to Myrtle Beach flights
Santa Ana to Charleston flights
Las Vegas to Charlotte flights
Ontario to Savannah flights
San Jose to Charlotte flights
San Francisco to Greenville flights
Ontario to Columbia flights
San Francisco to Myrtle Beach flights
San Diego to Savannah flights
Los Angeles to Greenville flights
Las Vegas to Charleston flights
Los Angeles to Columbia flights
San Jose to Charleston flights
San Jose to Savannah flights
Burbank to Charleston flights
Ontario to Myrtle Beach flights
Fresno to Charlotte flights
Santa Ana to Savannah flights
Las Vegas to Savannah flights
Ontario to Greenville flights
Reno to Charlotte flights
Palm Springs to Charlotte flights
San Diego to Myrtle Beach flights
Oakland to Charleston flights
Oakland to Charlotte flights
Santa Ana to Myrtle Beach flights
San Diego to Columbia flights
Burbank to Savannah flights
San Jose to Myrtle Beach flights
San Francisco to Augusta flights
Reno to Charleston flights
Los Angeles to Augusta flights
Long Beach to Charlotte flights
Sacramento to Myrtle Beach flights
San Diego to Greenville flights
Las Vegas to Columbia flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.