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$407+ Cheap flights from San Francisco Bay Area to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
SFO — FLO
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from San Francisco Bay Area to Florence

Cheapest flights from San Francisco Bay Area to Florence
Explore the most affordable flight options available from San Francisco Bay Area to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amSJC - FLO
2 stops9h 05mAmerican Airlines
Sat 12/276:30 pmFLO - SJC
2 stops17h 51mAmerican Airlines
Deal found 12/8$1,218

Find flight deals from San Francisco Bay Area to Florence

Keep the following information in mind while searching for San Francisco Bay Area to Florence flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$407
(American Airlines)
Provider with most accurate pricing for San Francisco-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Francisco-Florence flights.
Search Deals
From San Francisco Bay Area to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Francisco Bay Area to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from San Francisco Bay Area to Florence that are best for you.

Fly from

San Francisco Bay Area

Fly to

Florence

Route

Depart

Return

Price

San FranciscoFlorence

SFO - FLO

SFOFLO

San Francisco

Wed 5/27

1:46 pm-11:41 pm

1 stop6h 55m

Florence

Sat 5/30

2:35 pm-9:39 pm

1 stop10h 04m

$407

San JoseFlorence

SJC - FLO

SJCFLO

San Jose

Tue 12/23

6:00 am-6:05 pm

2 stops9h 05m

Florence

Sat 12/27

6:30 pm-9:21 am

2 stops17h 51m

$1,218

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Best time to book a flight from San Francisco Bay Area to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from San Francisco Bay Area with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Francisco Bay Area to Florence

What is the cheapest month to book a flight from San Francisco Bay Area to Florence, South Carolina?

Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Florence, South Carolina (average of $148). Flying from San Francisco Bay Area to Florence, South Carolina in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated December 9, 2025.
Read through reviews of airlines operating flights from San Francisco Bay Area to Florence, such as American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,045 reviews

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.5

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit
American Airlines
7.2
Good
11,045 reviews
American Airlines
7.2
Good
11,045 reviews

Boarding

7.5

Entertainment

6.9

Crew

8.0

Food

6.5

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from San Francisco Bay Area to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from San Francisco Bay Area?

    For a flight from San Francisco Bay Area to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city.

  • How long is the flight from San Francisco Bay Area to Florence, South Carolina?

    There are many flights that can get you from San Francisco Bay Area to Florence, South Carolina in 6h 55m. Fly via American Airlines to get the fastest option. Airlines will cover a distance of 2377 mi.

  • What are the most popular routes from San Francisco Bay Area to Florence, South Carolina?

    When deciding which route to take from San Francisco Bay Area to Florence, South Carolina consider Oakland - Florence, San Francisco - Florence or San Jose - Florence as they are the most popular.

  • Can I find deals for flights from San Francisco Bay Area to Florence that include hotel bookings?

    Yes. In addition to deals on San Francisco Bay Area to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Francisco Bay Area to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Francisco Bay Area to Florence.

  • Can I find deals for business class flights from San Francisco Bay Area to Florence?

    Yes. Cheapflights offers flight deals from San Francisco Bay Area to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Francisco Bay Area to Florence, South Carolina?

    Currently, May is the cheapest month in which you can book a flight from San Francisco Bay Area to Florence, South Carolina (average of $148). Flying from San Francisco Bay Area to Florence, South Carolina in March is currently the most expensive (average of $220). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from San Francisco Bay Area to Florence

Discover the top airline that operate flights from San Francisco Bay Area to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$400Average$512FlexibilityNo cancel feeOn-time71%

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