$399+ Cheap flights from San Antonio to Florence, SC (SAT - FLO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — FLO
Aug 5 — Aug 121
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Florence
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.
Round-trip from | $399 (American Airlines) |
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Find flight deals from San Antonio to Florence
Cheapest flights from San Antonio to FlorenceExplore the most affordable flight options available from San Antonio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.
Explore the most affordable flight options available from San Antonio to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/911:11 amSAT - FLO
1 stop5h 01mAmerican Airlines
Sat 9/136:14 amFLO - SAT
1 stop5h 07mAmerican Airlines
Deal found 7/29![American Airlines logo]()
$399
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from San Antonio to Florence that are best for you.
Fly from
San Antonio
Fly to
Florence
Route
Depart
Return
Price
San AntonioFlorence
SAT - FLO
SATFLO
San Antonio
Tue 9/9
4:49 pm-11:16 pm
1 stop5h 27m
Florence
Sat 9/13
6:14 am-10:21 am
1 stop5h 07m
$399
Best time to book a flight from San Antonio to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Florence
What is the cheapest month to book a flight from San Antonio to Florence, South Carolina?
Currently, January is the cheapest month in which you can book a flight from San Antonio to Florence, South Carolina (average of $366). Flying from San Antonio to Florence, South Carolina in October is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 31, 2025.
Peruse reviews from past customers who have flown with American Airlines from San Antonio to Florence to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Boarding
7.5
Food
6.5
Crew
8.0
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Comfort
7.2
Boarding
7.5
Food
6.5
Crew
8.0
Overall
7.2
Entertainment
6.9
Reviews
1 / 20
6.0
Goodsheila,Mar 2025
DFW - MSP
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
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Hartsville
Darlington