HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$404+ Cheap flights from Philadelphia to Florence, SC (PHL - FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
PHL — FLO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Philadelphia to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Philadelphia to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Philadelphia (PHL) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$404
(American Airlines)
From Philadelphia to Florence
Search Deals

Find flight deals from Philadelphia to Florence

Cheapest flights from Philadelphia to Florence
Explore the most affordable flight options available from Philadelphia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:55 pmPHL - FLO
1 stop6h 08mAmerican Airlines
Sat 10/182:29 pmFLO - PHL
1 stop5h 15mAmerican Airlines
Deal found 9/10$404
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Sat 1/312:51 pmFLO - PHL
1 stop4h 02mAmerican Airlines
Deal found 9/10$459
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Wed 12/315:15 amFLO - PHL
1 stop4h 24mAmerican Airlines
Deal found 9/10$461
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Wed 12/315:15 amFLO - PHL
2 stops9h 36mAmerican Airlines
Deal found 9/10$464
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Fri 1/212:51 pmFLO - PHL
1 stop5h 17mAmerican Airlines
Deal found 9/10$469
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:15 pmPHL - FLO
1 stop5h 00mAmerican Airlines
Wed 12/315:15 amFLO - PHL
2 stops9h 36mAmerican Airlines
Deal found 9/10$474
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:44 amPHL - FLO
2 stops7h 21mAmerican Airlines
Thu 1/112:51 pmFLO - PHL
1 stop5h 17mAmerican Airlines
Deal found 9/10$476
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/221:45 pmPHL - FLO
1 stop4h 20mAmerican Airlines
Thu 1/16:32 pmFLO - PHL
1 stop3h 21mAmerican Airlines
Deal found 9/10$479

Cheapflights Fare Finder

 
Customize your flight search to find flights from Philadelphia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Philadelphia to Florence that are best for you.

Fly from

Philadelphia

Fly to

Florence

Route

Depart

Return

Price

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Sat 10/11

5:55 pm-12:03 am

1 stop6h 08m

Florence

Sat 10/18

2:29 pm-7:44 pm

1 stop5h 15m

$404

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 12/24

7:15 pm-12:15 am

1 stop5h 00m

Florence

Sat 1/3

6:32 pm-11:54 pm

1 stop5h 22m

$459

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 12/23

7:15 pm-12:15 am

1 stop5h 00m

Florence

Wed 12/31

5:15 am-9:39 am

1 stop4h 24m

$459

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Wed 12/24

7:15 pm-12:15 am

1 stop5h 00m

Florence

Wed 12/31

6:32 pm-11:54 pm

1 stop5h 22m

$459

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 12/23

7:15 pm-12:15 am

1 stop5h 00m

Florence

Tue 12/30

6:32 pm-9:53 pm

1 stop3h 21m

$459

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Thu 12/25

7:15 pm-12:15 am

1 stop5h 00m

Florence

Wed 12/31

5:15 am-9:39 am

1 stop4h 24m

$461

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Tue 12/23

7:15 pm-12:15 am

1 stop5h 00m

Florence

Thu 1/1

6:32 pm-9:53 pm

1 stop3h 21m

$469

PhiladelphiaFlorence

PHL - FLO

PHLFLO

Philadelphia

Mon 12/22

1:45 pm-6:05 pm

1 stop4h 20m

Florence

Wed 12/31

5:15 am-9:39 am

1 stop4h 24m

$469

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Best time to book a flight from Philadelphia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Philadelphia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Philadelphia to Florence

What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $366). Flying from Philadelphia to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with American Airlines from Philadelphia to Florence to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Philadelphia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Philadelphia to Florence, South Carolina?

    American Airlines can get you from Philadelphia to Florence, South Carolina in just under 6h 08m. Your travel time can differ by up to . Airlines will cover a distance of 464 mi.

  • What is the cheapest airline to fly from Philadelphia to Florence, South Carolina round-trip?

    Our cheapest airline available from Philadelphia to Florence, South Carolina is American Airlines. Our recent data shows that you can find tickets from as low as $345 on this airline.

  • Can I find deals for flights from Philadelphia to Florence that include hotel bookings?

    Yes. In addition to deals on Philadelphia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Philadelphia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Philadelphia to Florence.

  • Can I find deals for business class flights from Philadelphia to Florence?

    Yes. Cheapflights offers flight deals from Philadelphia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Philadelphia to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Philadelphia to Florence, South Carolina (average of $366). Flying from Philadelphia to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Philadelphia to Florence

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to Charleston flights
Newark to Charleston flights
Newark to Charlotte flights
LaGuardia to Charlotte flights
LaGuardia to Charleston flights
John F Kennedy Intl to Savannah flights
Dulles Intl to Charlotte flights
Newark to Myrtle Beach flights
Philadelphia to Charlotte flights
LaGuardia to Myrtle Beach flights
John F Kennedy Intl to Myrtle Beach flights
Newark to Savannah flights
Dulles Intl to Charleston flights
Reagan-National to Charleston flights
Philadelphia to Charleston flights
Newark to Greenville flights
LaGuardia to Savannah flights
LaGuardia to Greenville flights
John F Kennedy Intl to Greenville flights
LaGuardia to Columbia flights
Philadelphia to Savannah flights
Philadelphia to Myrtle Beach flights
Dulles Intl to Savannah flights
John F Kennedy Intl to Columbia flights
Reagan-National to Savannah flights
Dulles Intl to Greenville flights
Reagan-National to Charlotte flights
Newark to Columbia flights
Philadelphia to Greenville flights
Dulles Intl to Myrtle Beach flights
John F Kennedy Intl to Hilton Head Island flights
Dulles Intl to Columbia flights
Reagan-National to Myrtle Beach flights
Allentown to Charlotte flights
Pittsburgh to Myrtle Beach flights
Reagan-National to Greenville flights
Allentown to Myrtle Beach flights
Newark to Hilton Head Island flights
LaGuardia to Hilton Head Island flights
Pittsburgh to Charlotte flights
Philadelphia to Columbia flights
Pittsburgh to Charleston flights
John F Kennedy Intl to Augusta flights
Reagan-National to Columbia flights
Scranton to Charlotte flights
Harrisburg to Charlotte flights
Newark to Augusta flights
Latrobe to Myrtle Beach flights
Allentown to Charleston flights

Top airline flying from Philadelphia to Florence

Discover the top airline that operate flights from Philadelphia to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$345Average$504FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.