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$180+ Cheap flights from Maryland to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
BWI — FLO
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Maryland to Florence

Keep the following information in mind while searching for Maryland to Florence flight deals. Data was last updated September 16, 2025.

Round-trip from

$214
(American Airlines)

One-way from

$180
(American Airlines)

Popular in

August

Cheapest in

June

Average price

$355
From Maryland to Florence
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One-way flight from Maryland to Florence
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Highest demand for flights based on searches. 7% potential increase in price ($23 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Maryland to Florence

Cheapest flights from Maryland to Florence
Explore the most affordable flight options available from Maryland to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/158:36 amDCA - FLO
2 stops6h 18mAmerican Airlines
Sat 10/182:29 pmFLO - DCA
1 stop4h 37mAmerican Airlines
Deal found 9/15$214
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1511:11 amBWI - FLO
1 stop3h 43mAmerican Airlines
Sat 10/185:14 amFLO - BWI
1 stop4h 41mAmerican Airlines
Deal found 9/15$317
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1510:25 amIAD - FLO
1 stop4h 29mAmerican Airlines
Sat 10/182:29 pmFLO - IAD
1 stop5h 16mAmerican Airlines
Deal found 9/15$323
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:24 pmDCA - FLO
1 stop5h 52mAmerican Airlines
Mon 9/225:37 pmFLO - DCA
1 stop4h 23mAmerican Airlines
Deal found 9/15$324
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:50 pmDCA - FLO
1 stop4h 13mAmerican Airlines
Mon 10/135:14 amFLO - DCA
1 stop4h 10mAmerican Airlines
Deal found 9/14$333
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/118:25 pmIAD - FLO
1 stop3h 38mAmerican Airlines
Sun 10/122:29 pmFLO - IAD
1 stop5h 16mAmerican Airlines
Deal found 9/14$333
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:41 pmBWI - FLO
1 stop4h 35mAmerican Airlines
Fri 10/312:27 pmFLO - BWI
1 stop5h 08mAmerican Airlines
Deal found 9/13$359
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/118:25 pmIAD - FLO
1 stop3h 38mAmerican Airlines
Mon 10/135:14 amFLO - IAD
1 stop3h 35mAmerican Airlines
Deal found 9/14$363
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:24 pmDCA - FLO
1 stop5h 52mAmerican Airlines
Sun 9/2111:18 amFLO - DCA
1 stop4h 41mAmerican Airlines
Deal found 9/15$379
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1912:48 pmIAD - FLO
1 stop4h 24mAmerican Airlines
Sun 9/215:14 amFLO - IAD
1 stop6h 20mAmerican Airlines
Deal found 9/15$379
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/106:34 amIAD - FLO
1 stop4h 12mAmerican Airlines
Mon 10/132:29 pmFLO - IAD
1 stop5h 16mAmerican Airlines
Deal found 9/15$387
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:00 amBWI - FLO
1 stop5h 46mAmerican Airlines
Mon 10/132:29 pmFLO - BWI
1 stop4h 01mAmerican Airlines
Deal found 9/14$397

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maryland to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Maryland to Florence that are best for you.

Fly from

Maryland

Fly to

Florence

Route

Depart

Return

Price

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Wed 10/15

8:36 am-2:54 pm

2 stops6h 18m

Florence

Sat 10/18

2:29 pm-7:06 pm

1 stop4h 37m

$214

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Wed 10/15

11:11 am-2:54 pm

1 stop3h 43m

Florence

Sat 10/18

5:14 am-9:55 am

1 stop4h 41m

$317

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Sun 11/9

6:20 am-10:45 am

1 stop4h 25m

Florence

Sun 11/16

6:32 pm-12:30 am

1 stop5h 58m

$317

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Thu 10/30

10:25 am-2:54 pm

1 stop4h 29m

Florence

Fri 11/28

6:33 pm-11:59 pm

1 stop5h 26m

$323

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Wed 10/15

10:25 am-2:54 pm

1 stop4h 29m

Florence

Sat 10/18

2:29 pm-7:45 pm

1 stop5h 16m

$323

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Tue 10/14

10:25 am-2:54 pm

1 stop4h 29m

Florence

Tue 10/21

6:14 am-9:55 am

1 stop3h 41m

$323

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 10/11

5:30 pm-12:03 am

1 stop6h 33m

Florence

Sun 10/12

5:14 am-9:24 am

1 stop4h 10m

$333

Washington, D.C.Florence

DCA - FLO

DCAFLO

Washington, D.C. Reagan-National

Sat 10/11

7:50 pm-12:03 am

1 stop4h 13m

Florence

Mon 10/13

5:14 am-9:24 am

1 stop4h 10m

$333

Washington, D.C.Florence

IAD - FLO

IADFLO

Washington, D.C. Dulles Intl

Sat 10/11

8:25 pm-12:03 am

1 stop3h 38m

Florence

Sun 10/12

2:29 pm-7:45 pm

1 stop5h 16m

$333

BaltimoreFlorence

BWI - FLO

BWIFLO

Baltimore/Washington

Mon 9/29

6:41 pm-11:16 pm

1 stop4h 35m

Florence

Thu 10/2

4:57 pm-10:29 pm

1 stop5h 32m

$359

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 36 results
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Best time to book a flight from Maryland to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Maryland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maryland to Florence

What is the cheapest month to book a flight from Maryland to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Maryland to Florence, South Carolina (average of $366). Flying from Maryland to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MD to FLO?

Find hourly flight availability from Maryland to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

When flying from Maryland to Florence, South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Maryland to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Maryland?

    If you book a flight to Florence from Maryland, you will be flying to Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence.

  • How long is the flight from Maryland to Florence, South Carolina?

    There are many flights that can get you from Maryland to Florence, South Carolina in 6h 18m. Fly via American Airlines to get the fastest option. The distance from Maryland to Florence, South Carolina is about 355 mi.

  • What are the most popular routes from Maryland to Florence, South Carolina?

    Most travelers choose Washington, D.C. Dulles Intl - Florence, Baltimore/Washington - Florence or Washington, D.C. Reagan-National - Florence when deciding on the best route from Maryland to Florence, South Carolina.

  • Can I find deals for flights from Maryland to Florence that include hotel bookings?

    Yes. In addition to deals on Maryland to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maryland to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maryland to Florence.

  • Can I find deals for business class flights from Maryland to Florence?

    Yes. Cheapflights offers flight deals from Maryland to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maryland to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Maryland to Florence, South Carolina (average of $366). Flying from Maryland to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Maryland to Florence

Discover the top airline that operate flights from Maryland to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$237Average$349FlexibilityNo cancel feeOn-time71%

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