HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$327+ Cheap flights from LaGuardia, NY (LGA) to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
LGA — FLO
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from LaGuardia to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from LaGuardia to Florence

Discover tips and strategies to find the most affordable flight options for your journey from LaGuardia (LGA) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$361
(American Airlines)

One-way from

$327
(American Airlines)

Popular in

April

Cheapest in

March

Average price

$391
From New York LaGuardia to Florence
Search Deals
One-way flight from New York LaGuardia to Florence
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($24 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from LaGuardia to Florence

Cheapest flights from LaGuardia to Florence
Explore the most affordable flight options available from LaGuardia to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:57 amLGA - FLO
1 stop6h 07mAmerican Airlines
Sat 10/185:14 amFLO - LGA
1 stop3h 49mAmerican Airlines
Deal found 9/17$327
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:00 amLGA - FLO
1 stop6h 12mAmerican Airlines
Sat 10/45:37 pmFLO - LGA
1 stop6h 08mAmerican Airlines
Deal found 9/15$361
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:51 amLGA - FLO
1 stop7h 03mAmerican Airlines
Wed 10/226:14 amFLO - LGA
1 stop4h 51mAmerican Airlines
Deal found 9/15$363
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/155:28 pmLGA - FLO
1 stop5h 45mAmerican Airlines
Tue 10/216:14 amFLO - LGA
2 stops9h 12mAmerican Airlines
Deal found 9/15$368
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amLGA - FLO
1 stop4h 46mAmerican Airlines
Mon 10/2011:11 amFLO - LGA
1 stop6h 09mAmerican Airlines
Deal found 9/16$387
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/159:00 amLGA - FLO
1 stop5h 54mAmerican Airlines
Thu 10/232:29 pmFLO - LGA
1 stop4h 00mAmerican Airlines
Deal found 9/15$410
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2012:20 pmLGA - FLO
1 stop4h 52mAmerican Airlines
Mon 9/226:14 amFLO - LGA
1 stop5h 15mAmerican Airlines
Deal found 9/15$426
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/235:07 pmLGA - FLO
1 stop6h 09mAmerican Airlines
Tue 9/306:14 amFLO - LGA
1 stop5h 15mAmerican Airlines
Deal found 9/17$431
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/239:37 amLGA - FLO
2 stops7h 35mAmerican Airlines
Wed 10/15:37 pmFLO - LGA
1 stop6h 08mAmerican Airlines
Deal found 9/17$436

Cheapflights Fare Finder

 
Customize your flight search to find flights from LaGuardia to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from New York LaGuardia Airport to Florence that are best for you.

Fly from

LaGuardia

Fly to

Florence

Route

Depart

Return

Price

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 10/11

7:57 am-2:04 pm

1 stop6h 07m

Florence

Sat 10/18

5:14 am-9:03 am

1 stop3h 49m

$327

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 10/15

7:51 am-2:54 pm

1 stop7h 03m

Florence

Wed 10/22

6:14 am-11:05 am

1 stop4h 51m

$363

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 10/18

7:57 am-2:04 pm

1 stop6h 07m

Florence

Tue 10/21

6:14 am-11:05 am

1 stop4h 51m

$363

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Sat 10/18

7:57 am-2:04 pm

1 stop6h 07m

Florence

Wed 10/22

6:14 am-3:00 pm

2 stops8h 46m

$368

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 10/15

5:28 pm-11:13 pm

1 stop5h 45m

Florence

Tue 10/21

6:14 am-3:26 pm

2 stops9h 12m

$368

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 10/17

10:10 am-2:04 pm

1 stop3h 54m

Florence

Mon 10/20

2:29 pm-8:05 pm

1 stop5h 36m

$387

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Fri 10/24

5:28 pm-11:13 pm

1 stop5h 45m

Florence

Mon 10/27

11:11 am-3:14 pm

1 stop4h 03m

$387

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 10/15

9:00 am-2:54 pm

1 stop5h 54m

Florence

Thu 10/23

2:29 pm-6:29 pm

1 stop4h 00m

$410

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Wed 10/15

7:51 am-2:54 pm

1 stop7h 03m

Florence

Mon 10/20

11:11 am-4:17 pm

1 stop5h 06m

$410

New YorkFlorence

LGA - FLO

LGAFLO

New York LaGuardia

Thu 10/16

5:12 pm-12:03 am

1 stop6h 51m

Florence

Wed 10/22

6:14 am-11:05 am

1 stop4h 51m

$410

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 12 results
1
2

Best time to book a flight from LaGuardia to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from LaGuardia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New York LaGuardia Airport to Florence

What is the cheapest month to book a flight from New York LaGuardia Airport to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from New York LaGuardia Airport to Florence, South Carolina (average of $366). Flying from New York LaGuardia Airport to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LGA to FLO?

Find hourly flight availability from LaGuardia to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

It’s typically best to fly out from New York LaGuardia Airport to Florence, South Carolina at noon. Doing so could potentially save you 3% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown American Airlines from New York LaGuardia Airport to Florence. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Boarding

7.5

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from LaGuardia to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from New York LaGuardia?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly into when you book flights from New York LaGuardia to Florence. 1 airline have flights to Florence from New York LaGuardia on a regular basis. Booking flights from New York LaGuardia to Florence should not be difficult; the airport handles an average of 0 inbound flights from New York LaGuardia per day.

  • How long is the flight from New York LaGuardia Airport to Florence, South Carolina?

    Airlines like American Airlines fly from New York LaGuardia Airport to Florence, South Carolina in about 6h 07m. The time it takes to get you to your destination can typically vary by up to . There are 556 mi between New York LaGuardia Airport and Florence, South Carolina.

  • What is the cheapest airline to fly from New York LaGuardia Airport to Florence, South Carolina round-trip?

    According to our current data, American Airlines ($208), offers the cheapest pricing from New York LaGuardia Airport to Florence, South Carolina. American Airlines is priced at 37% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from LaGuardia to Florence that include hotel bookings?

    Yes. In addition to deals on LaGuardia to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from LaGuardia to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from LaGuardia to Florence.

  • Can I find deals for business class flights from LaGuardia to Florence?

    Yes. Cheapflights offers flight deals from LaGuardia to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from New York LaGuardia Airport to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from New York LaGuardia Airport to Florence, South Carolina (average of $366). Flying from New York LaGuardia Airport to Florence, South Carolina in October is currently the most expensive (average of $501). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for LaGuardia to Florence

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
LaGuardia to Charlotte flights
Newark to Charleston flights
Newark to Charlotte flights
John F Kennedy Intl to Charleston flights
LaGuardia to Charleston flights
John F Kennedy Intl to Savannah flights
Newark to Myrtle Beach flights
LaGuardia to Savannah flights
Newark to Savannah flights
John F Kennedy Intl to Myrtle Beach flights
LaGuardia to Myrtle Beach flights
LaGuardia to Greenville flights
John F Kennedy Intl to Greenville flights
Newark to Greenville flights
LaGuardia to Columbia flights
John F Kennedy Intl to Columbia flights
Stewart to Myrtle Beach flights
Stewart to Charleston flights
Newark to Columbia flights
LaGuardia to Hilton Head Island flights
John F Kennedy Intl to Hilton Head Island flights
Newark to Hilton Head Island flights
John F Kennedy Intl to Augusta flights
Newark to Augusta flights
LaGuardia to Augusta flights
Stewart to Savannah flights
Newark to Florence flights
John F Kennedy Intl to Florence flights
Stewart to Greenville flights
Stewart to Charlotte flights
Stewart to Columbia flights
Stewart to Florence flights
Stewart to Augusta flights

Top airline flying from LaGuardia to Florence

Discover the top airline that operate flights from LaGuardia to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$208Average$366FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.