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$387+ Cheap flights from Clearwater, FL to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/19. Fares are subject to change and may not be available on all flights or dates of travel.
MCO — FLO
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Clearwater to Florence

Cheapest flights from Clearwater to Florence
Explore the most affordable flight options available from Clearwater to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:25 amTPA - FLO
1 stop4h 01mAmerican Airlines
Mon 12/295:15 amFLO - TPA
1 stop5h 30mAmerican Airlines
Deal found 12/10$482
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amTPA - FLO
1 stop6h 26mAmerican Airlines
Thu 12/258:00 amFLO - TPA
1 stop6h 49mAmerican Airlines
Deal found 12/11$512
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:40 pmTPA - FLO
1 stop4h 35mAmerican Airlines
Sun 12/2112:51 pmFLO - TPA
1 stop3h 52mAmerican Airlines
Deal found 12/11$517

Find flight deals from Clearwater to Florence

Keep the following information in mind while searching for Clearwater to Florence flight deals. Data was last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$482
(American Airlines)

One-way from

$387
(American Airlines)
Provider with most accurate pricing for Tampa-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa-Florence flights.
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From Clearwater to Florence
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One-way flight from Clearwater to Florence
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Clearwater to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Clearwater to Florence that are best for you.

Fly from

Clearwater

Fly to

Florence

Route

Depart

Return

Price

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Wed 12/24

8:25 am-12:26 pm

1 stop4h 01m

Florence

Mon 12/29

5:15 am-10:45 am

1 stop5h 30m

$482

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Tue 12/23

6:00 am-12:26 pm

1 stop6h 26m

Florence

Thu 12/25

8:00 am-2:49 pm

1 stop6h 49m

$512

TampaFlorence

TPA - FLO

TPAFLO

Tampa

Fri 12/19

8:25 am-12:26 pm

1 stop4h 01m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Best time to book a flight from Clearwater to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Clearwater with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Clearwater to Florence

What is the cheapest month to book a flight from Clearwater to Florence, South Carolina?

Currently, February is the cheapest month in which you can book a flight from Clearwater to Florence, South Carolina (average of $41). Flying from Clearwater to Florence, South Carolina in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Clearwater to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Clearwater?

    Florence (FLO) is the airport you will fly into if you book a flight from Clearwater to Florence. You should not have trouble finding flights to Florence from Clearwater; the airport handles an average of 0 inbound flights from Clearwater per day. You should also have plenty of airline options to choose from since 0 airlines have flights to the Florence airport from Clearwater. It is only a 2.3 mi journey from Florence (FLO) to Florence’s city center.

  • How long is the flight from Clearwater to Florence, South Carolina?

    Departing from Clearwater to Florence, South Carolina will take you 4h 01m. The distance from Clearwater to Florence, South Carolina is about 460 mi.

  • Can I find deals for flights from Clearwater to Florence that include hotel bookings?

    Yes. In addition to deals on Clearwater to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Clearwater to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Clearwater to Florence.

  • Can I find deals for business class flights from Clearwater to Florence?

    Yes. Cheapflights offers flight deals from Clearwater to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Clearwater to Florence, South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Clearwater to Florence, South Carolina (average of $41). Flying from Clearwater to Florence, South Carolina in June is currently the most expensive (average of $76). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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