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$103+ Cheap flights from Key West (EYW) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/11. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — RDU
Oct 14 — Oct 211
Tue 10/14
Tue 10/21
1 adult, Economy
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Cheap flight deals from Key West to Durham

Keep the following information in mind while searching for Key West to Durham flight deals. Data was last updated September 14, 2025.

Round-trip from

$162
(Expedia)

One-way from

$103
(Expedia)

Popular in

February

Cheapest in

June

Average price

$290
From Key West to Durham
Search Deals
One-way flight from Key West to Durham
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($13 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Key West to Durham

Cheapest flights from Key West to Durham
Explore the most affordable flight options available from Key West to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2025.

This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/311:11 amEYW - RDU
Nonstop2h 30mBreeze Airways
Mon 10/68:01 amRDU - EYW
Nonstop2h 30mBreeze Airways
Deal found 9/14$162
This Expedia deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:32 pmEYW - RDU
1 stop20h 23mBreeze Airways
Fri 10/38:01 amRDU - EYW
Nonstop2h 30mBreeze Airways
Deal found 9/13$181
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:57 amEYW - RDU
1 stop26h 01mBreeze Airways
Wed 11/193:07 pmRDU - EYW
1 stop17h 08mBreeze Airways
Deal found 9/14$193
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/198:47 amEYW - RDU
1 stop24h 10mMultiple Airlines
Sun 9/219:55 pmRDU - EYW
1 stop10h 12mMultiple Airlines
Deal found 9/13$200
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/144:18 pmEYW - RDU
1 stop5h 46mAmerican Airlines
Wed 11/1910:15 amRDU - EYW
2 stops6h 46mAmerican Airlines
Deal found 9/14$243
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2912:32 pmEYW - RDU
1 stop20h 23mMultiple Airlines
Fri 10/36:42 pmRDU - EYW
2 stops15h 25mMultiple Airlines
Deal found 9/13$256

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
Use the filters below to find and compare flights from Key West to Durham that are best for you.

Fly from

Key West

Fly to

Durham

Route

Depart

Return

Price

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Fri 10/3

11:11 am-1:41 pm

Nonstop2h 30m

Raleigh-Durham

Mon 10/6

8:01 am-10:31 am

Nonstop2h 30m

$162

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 9/29

12:32 pm-8:55 am

1 stop20h 23m

Raleigh-Durham

Fri 10/3

8:01 am-10:31 am

Nonstop2h 30m

$181

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Fri 11/14

9:57 am-11:58 am

1 stop26h 01m

Raleigh-Durham

Wed 11/19

3:07 pm-8:15 am

1 stop17h 08m

$193

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Fri 11/14

4:18 pm-10:04 pm

1 stop5h 46m

Raleigh-Durham

Wed 11/19

10:15 am-5:01 pm

2 stops6h 46m

$243

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 9/29

12:32 pm-8:55 am

1 stop20h 23m

Raleigh-Durham

Fri 10/3

6:42 pm-10:07 am

2 stops15h 25m

$256

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Sun 1/11

11:01 am-8:58 am

1 stop21h 57m

$103

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 12/29

7:52 pm-12:36 am

1 stop4h 44m

$229

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Sun 1/11

3:46 pm-1:19 pm

3 stops21h 33m

$232

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 12/29

11:11 am-1:41 pm

Nonstop2h 30m

$318

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Sun 10/5

10:59 am-7:21 am

2 stops20h 22m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 11 results
1
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Best time to book a flight from Key West to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Durham

What is the cheapest month to book a flight from Key West to Durham?

Currently, August is the cheapest month in which you can book a flight from Key West to Durham (average of $206). Flying from Key West to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from EYW to DU8?

Find hourly flight availability from Key West to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 14, 2025.

When flying from Key West to Durham, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated September 14, 2025.
Peruse reviews from past customers who have flown with American Airlines from Key West to Durham to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Food

6.4

Boarding

7.5

Comfort

7.2

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Apr 2025

MYR - CLT

This flight was impacted by a nearly 4, yes 4 hour delay. They replaced a 777 with another one and it had to be cleaned and catered before we could depart. Great crew did it without complaint.

Related info for your journey

Find useful and relevant information for your journey from Key West to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to Durham?

    Most people fly from Key West (EYW) if they book a flight from Key West to Durham. On average, Key West has 0 outbound flights to Durham per day from 1 airline. Key West is conveniently located just 2.6 mi from Key West’s city center.

  • How long is the flight from Key West to Durham?

    For as low as $162, Breeze Airways can have you in Durham from Key West in 2h 30m. The distance between Key West and Durham is about 802 mi. Most flights are nonstop.

  • What are the cheapest flights from Key West to Durham?

    The cheapest flight price from Key West to Durham is $139. On average you can expect to pay $139. The most popular route, (Key West - Raleigh-Durham), can usually be booked for $405.

  • Can I find deals for flights from Key West to Durham that include hotel bookings?

    Yes. In addition to deals on Key West to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Durham.

  • Can I find deals for business class flights from Key West to Durham?

    Yes. Cheapflights offers flight deals from Key West to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Durham?

    Currently, August is the cheapest month in which you can book a flight from Key West to Durham (average of $206). Flying from Key West to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Key West to Durham

Discover the top airline that operate flights from Key West to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$238Average$283FlexibilityNo cancel feeOn-time71%

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