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$79+ Cheap flights from Key West (EYW) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — RDU
Jan 16 — Jan 231
Fri 1/16
Fri 1/23
1 adult, Economy
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Cheap flight deals from Key West to Durham

Cheapest flights from Key West to Durham
Explore the most affordable flight options available from Key West to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 17, 2025.

This Breeze Airways deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:11 amEYW - RDU
Nonstop2h 30mBreeze Airways
Mon 12/228:01 amRDU - EYW
Nonstop2h 30mBreeze Airways
Deal found 12/16$218
This Breeze Airways deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/188:55 amEYW - RDU
1 stop6h 52mBreeze Airways
Sun 12/219:49 pmRDU - EYW
1 stop14h 41mBreeze Airways
Deal found 12/16$225
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1811:47 amEYW - RDU
1 stop4h 44mAmerican Airlines
Sun 12/2111:25 amRDU - EYW
2 stops5h 44mAmerican Airlines
Deal found 12/17$531
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:43 pmEYW - RDU
1 stop6h 03mUnited Airlines
Mon 12/227:40 pmRDU - EYW
2 stops21h 33mUnited Airlines
Deal found 12/16$648

Find flight deals from Key West to Durham

Keep the following information in mind while searching for Key West to Durham flight deals. Data was last updated December 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$339
(United Airlines)

One-way from

$79
(Breeze Airways)

Popular in

February

Cheapest in

June

Average price

$409
Provider with most accurate pricing for Key West-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Key West-Raleigh-Durham flights.
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From Key West to Durham
Search Deals
One-way flight from Key West to Durham
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($65 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
Use the filters below to find and compare flights from Key West to Durham that are best for you.

Fly from

Key West

Fly to

Durham

Route

Depart

Return

Price

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Thu 1/29

2:25 pm-9:05 pm

1 stop6h 40m

Raleigh-Durham

Sun 2/1

6:00 am-1:03 pm

1 stop7h 03m

$339

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 12/29

11:11 am-1:41 pm

Nonstop2h 30m

$79

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Fri 12/26

11:11 am-1:41 pm

Nonstop2h 30m

$93

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Thu 12/25

8:55 am-3:47 pm

1 stop6h 52m

$95

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Sat 1/10

10:49 am-8:58 am

1 stop22h 09m

$97

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 2/2

1:06 pm-1:59 pm

1 stop24h 53m

$99

Key WestRaleigh

EYW - RDU

EYWRDU

Key West

Mon 2/2

11:04 am-1:24 pm

Nonstop2h 20m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Best time to book a flight from Key West to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Durham

What is the cheapest month to book a flight from Key West to Durham?

Currently, July is the cheapest month in which you can book a flight from Key West to Durham (average of $216). Flying from Key West to Durham in August is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from EYW to DU8?

Find hourly flight availability from Key West to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 17, 2025.

One of the essential ways to save on airfare from Key West to Durham is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the morning could potentially save you up to 38% on airfare.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated December 17, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Key West to Durham to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Crew

8.5

Food

7.3

Overall

7.9

Comfort

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Key West to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Key West to Durham?

    Most people fly from Key West (EYW) if they book a flight from Key West to Durham. On average, Key West has 0 outbound flights to Durham per day from 2 airlines. Key West is conveniently located just 2.6 mi from Key West’s city center.

  • How long is the flight from Key West to Durham?

    For as low as $339, United Airlines can have you in Durham from Key West in 6h 40m. The distance between Key West and Durham is about 802 mi.

  • What are the cheapest flights from Key West to Durham?

    The cheapest flight price from Key West to Durham is $99. On average you can expect to pay $464. The most popular route, (Key West - Raleigh-Durham), can usually be booked for $232.

  • Can I find deals for flights from Key West to Durham that include hotel bookings?

    Yes. In addition to deals on Key West to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Durham.

  • Can I find deals for business class flights from Key West to Durham?

    Yes. Cheapflights offers flight deals from Key West to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Durham?

    Currently, July is the cheapest month in which you can book a flight from Key West to Durham (average of $216). Flying from Key West to Durham in August is currently the most expensive (average of $428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Key West to Durham

Discover the top 2 airlines that operate flights from Key West to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$232Average$428FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$253Average$359FlexibilityNo cancel feeOn-time71%

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