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Durham

$55+ Cheap flights from Iowa to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — RDU
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Cheap flight deals from Iowa to Durham

Keep the following information in mind while searching for Iowa to Durham flight deals. Data was last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$151
(Mytrip)

One-way from

$55
(Priceline)

Popular in

December

Cheapest in

September

Average price

$378
Provider with most accurate pricing for Des Moines-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Raleigh-Durham flights.
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From Iowa to Durham
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One-way flight from Iowa to Durham
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Highest demand for flights based on searches. 7% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Iowa to Durham

Cheapest flights from Iowa to Durham
Explore the most affordable flight options available from Iowa to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This Mytrip deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:50 pmOMA - RDU
1 stop5h 22mFrontier
Thu 12/116:26 pmRDU - OMA
1 stop20h 05mFrontier
Deal found 10/31$151
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:40 amDSM - RDU
1 stop5h 55mMultiple Airlines
Wed 12/38:39 pmRDU - DSM
1 stop26h 42mMultiple Airlines
Deal found 11/2$241
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:30 amCID - RDU
1 stop4h 44mAmerican Airlines
Tue 12/308:17 pmRDU - CID
1 stop4h 41mAmerican Airlines
Deal found 11/2$249
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amALO - RDU
1 stop5h 34mAmerican Airlines
Sun 12/79:32 amRDU - ALO
1 stop6h 24mAmerican Airlines
Deal found 11/1$249
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/138:00 amCID - RDU
2 stops10h 13mUnited Airlines
Thu 1/16:31 amRDU - CID
1 stop5h 03mUnited Airlines
Deal found 11/1$254
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/277:30 amDSM - RDU
1 stop23h 49mMultiple Airlines
Wed 12/38:39 pmRDU - DSM
1 stop26h 42mMultiple Airlines
Deal found 11/2$275
This Booking.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1411:29 amOMA - RDU
1 stop10h 36mFrontier
Sun 11/165:21 pmRDU - OMA
1 stop27h 45mFrontier
Deal found 10/31$276
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:55 pmOMA - RDU
1 stop5h 04mDelta
Tue 12/96:00 amRDU - OMA
1 stop6h 44mDelta
Deal found 11/2$277
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2311:14 amDSM - RDU
1 stop6h 14mFrontier
Sat 1/38:14 pmRDU - DSM
1 stop14h 08mFrontier
Deal found 11/1$279
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:22 pmMLI - RDU
1 stop4h 47mAmerican Airlines
Sun 11/165:00 amRDU - MLI
1 stop6h 40mAmerican Airlines
Deal found 10/31$279
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:00 amDSM - RDU
2 stops11h 49mMultiple Airlines
Sun 11/238:39 pmRDU - DSM
1 stop17h 16mMultiple Airlines
Deal found 11/1$281
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:30 amCID - RDU
1 stop6h 11mUnited Airlines
Wed 12/3110:45 amRDU - CID
2 stops9h 38mUnited Airlines
Deal found 11/2$282

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from Iowa to Durham that are best for you.

Fly from

Iowa

Fly to

Durham

Route

Depart

Return

Price

OmahaRaleigh

OMA - RDU

OMARDU

Omaha Eppley Airfield

Fri 12/5

5:50 pm-12:12 am

1 stop5h 22m

Raleigh-Durham

Thu 12/11

6:26 pm-1:31 pm

1 stop20h 05m

$151

OmahaRaleigh

OMA - RDU

OMARDU

Omaha Eppley Airfield

Sun 1/11

2:37 pm-6:41 pm

1 stop27h 04m

Raleigh-Durham

Thu 1/15

2:52 pm-10:20 am

2 stops20h 28m

$218

Cedar RapidsRaleigh

CID - RDU

CIDRDU

Cedar Rapids

Thu 12/25

8:30 am-2:14 pm

1 stop4h 44m

Raleigh-Durham

Tue 12/30

8:17 pm-11:58 pm

1 stop4h 41m

$249

Cedar RapidsRaleigh

CID - RDU

CIDRDU

Cedar Rapids

Sat 12/13

8:00 am-2:07 pm

1 stop5h 07m

Raleigh-Durham

Thu 1/1

6:31 am-10:34 am

1 stop5h 03m

$249

Cedar RapidsRaleigh

CID - RDU

CIDRDU

Cedar Rapids

Thu 11/27

7:00 am-2:04 pm

1 stop6h 04m

Raleigh-Durham

Tue 12/2

6:56 pm-11:19 pm

1 stop5h 23m

$249

Cedar RapidsRaleigh

CID - RDU

CIDRDU

Cedar Rapids

Sat 2/14

4:15 pm-11:57 pm

1 stop6h 42m

Raleigh-Durham

Wed 2/18

11:35 am-3:47 pm

1 stop5h 12m

$249

Cedar RapidsRaleigh

CID - RDU

CIDRDU

Cedar Rapids

Fri 1/30

3:41 pm-11:44 pm

1 stop7h 03m

Raleigh-Durham

Sun 2/1

7:35 pm-11:05 pm

1 stop4h 30m

$249

MolineRaleigh

MLI - RDU

MLIRDU

Moline Quad-City

Sat 2/21

5:00 pm-12:11 am

1 stop6h 11m

Raleigh-Durham

Tue 2/24

5:39 pm-10:32 pm

1 stop5h 53m

$249

WaterlooRaleigh

ALO - RDU

ALORDU

Waterloo

Wed 12/3

6:00 am-12:34 pm

1 stop5h 34m

Raleigh-Durham

Sun 12/7

9:32 am-2:56 pm

1 stop6h 24m

$249

Des MoinesRaleigh

DSM - RDU

DSMRDU

Des Moines

Mon 11/24

8:00 am-12:10 pm

2 stops27h 10m

Raleigh-Durham

Wed 12/3

8:39 pm-10:21 pm

1 stop26h 42m

$257

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 57 results
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Best time to book a flight from Iowa to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Durham

What is the cheapest month to book a flight from Iowa to Durham?

Currently, January is the cheapest month in which you can book a flight from Iowa to Durham (average of $146). Flying from Iowa to Durham in February is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to DU8?

Find hourly flight availability from Iowa to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

It’s optimal to fly from Iowa to Durham in the evening. By choosing this option you can save up to 38% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Iowa to Durham?

    A quick flight from Iowa to Durham can take about 4h 44m. Frontier provides one of the quickest options available for as low as $249. Airlines will cover a distance of 808 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Iowa to Durham?

    While some choose either Omaha Eppley Airfield - Raleigh-Durham or Cedar Rapids - Raleigh-Durham, Des Moines - Raleigh-Durham is the most popular route from Iowa to Durham.

  • Can I find deals for flights from Iowa to Durham that include hotel bookings?

    Yes. In addition to deals on Iowa to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Durham.

  • Can I find deals for business class flights from Iowa to Durham?

    Yes. Cheapflights offers flight deals from Iowa to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Durham?

    Currently, January is the cheapest month in which you can book a flight from Iowa to Durham (average of $146). Flying from Iowa to Durham in February is currently the most expensive (average of $248). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Iowa to Durham

Discover the top 4 airlines that operate flights from Iowa to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapest$216Average$426FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$223Average$369FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$300FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$355FlexibilityNo cancel feeOn-time69%

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