HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Dominican Republic

$157+ Cheap flights from Missouri to the Dominican Republic

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PUJ
nov. 20 — nov. 271
jue. 11/20
jue. 11/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Dominican Republic with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Dominican Republic

Cheapest flights from Missouri to Dominican Republic
Explore the most affordable flight options available from Missouri to Dominican Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 21, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:51 pmMCI - PUJ
1 stop19h 59mSpirit Airlines
vie. 12/126:08 pmPUJ - MCI
1 stop25h 38mSpirit Airlines
Deal found 10/21$351
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/17:31 pmMCI - SDQ
1 stop17h 59mSpirit Airlines
dom. 12/74:31 pmSDQ - MCI
1 stop27h 15mSpirit Airlines
Deal found 10/20$354
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/56:51 pmMCI - PUJ
1 stop19h 59mSpirit Airlines
dom. 12/146:08 pmPUJ - MCI
1 stop25h 38mSpirit Airlines
Deal found 10/20$366
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/17:31 pmMCI - SDQ
1 stop17h 59mMultiple Airlines
jue. 12/114:31 pmSDQ - MCI
2 stops20h 47mMultiple Airlines
Deal found 10/20$366
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:21 pmSTL - PUJ
1 stop18h 59mMultiple Airlines
jue. 11/203:11 pmPUJ - STL
1 stop10h 46mMultiple Airlines
Deal found 10/20$367
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/286:00 amMCI - PUJ
1 stop12h 25mMultiple Airlines
jue. 12/46:08 pmPUJ - MCI
1 stop25h 38mMultiple Airlines
Deal found 10/21$367
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:21 pmSTL - PUJ
1 stop18h 59mMultiple Airlines
jue. 11/134:25 pmPUJ - STL
2 stops25h 36mMultiple Airlines
Deal found 10/20$370
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/512:13 pmMCI - PUJ
2 stops26h 18mMultiple Airlines
vie. 12/126:08 pmPUJ - MCI
1 stop25h 38mMultiple Airlines
Deal found 10/21$376
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:21 pmSTL - PUJ
1 stop18h 59mMultiple Airlines
sáb. 11/154:25 pmPUJ - STL
2 stops19h 47mMultiple Airlines
Deal found 10/20$377
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/36:00 amMCI - PUJ
1 stop28h 45mSpirit Airlines
jue. 11/61:40 pmPUJ - MCI
1 stop24h 48mSpirit Airlines
Deal found 10/20$378
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 11/36:00 amMCI - PUJ
1 stop28h 45mMultiple Airlines
mar. 11/1110:45 amPUJ - MCI
1 stop27h 43mMultiple Airlines
Deal found 10/20$379
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/96:21 pmSTL - PUJ
1 stop18h 59mMultiple Airlines
mar. 11/1810:45 amPUJ - STL
2 stops38h 16mMultiple Airlines
Deal found 10/20$381

Cheap flight deals from Missouri to Dominican Republic

Keep the following information in mind while searching for Missouri to Dominican Republic flight deals. Data was last updated octubre 21, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$351
(Kiwi.com)

One-way from

$157
(Kiwi.com)

Popular in

November

Cheapest in

September

Average price

$634

Good round-trip deal

$495 or less

Good one-way deal

$256 or less
Provider with most accurate pricing for Lambert-St Louis-Punta Cana flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Punta Cana flights.
Search Deals
From Missouri to Dominican Republic
Search Deals
One-way flight from Missouri to Dominican Republic
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Missouri to Dominican Republic.
Search Deals
Price to beat on a one-way flight from Missouri to Dominican Republic.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Dominican Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 21, 2025.
Use the filters below to find and compare flights from Missouri to the Dominican Republic that are best for you.

Fly from

Missouri

Fly to

Dominican Republic

Route

Depart

Return

Price

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 12/1

7:31 pm-3:30 pm

1 stop17h 59m

Santo Domingo Las Americas

dom. 12/7

4:31 pm-5:46 pm

1 stop27h 15m

$354

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

lun. 1/26

5:11 pm-5:06 pm

2 stops21h 55m

Santiago de los Caballeros

vie. 1/30

6:18 pm-1:53 pm

1 stop21h 35m

$375

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

jue. 12/4

8:09 pm-4:29 pm

2 stops18h 20m

Santo Domingo Las Americas

jue. 12/11

4:31 pm-5:46 pm

1 stop27h 15m

$389

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mar. 12/2

12:58 pm-3:30 pm

2 stops24h 32m

Santo Domingo Las Americas

jue. 12/11

4:31 pm-5:46 pm

1 stop27h 15m

$397

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

mié. 12/3

6:00 am-5:25 am

2 stops21h 25m

Santo Domingo Las Americas

dom. 12/7

4:31 pm-5:46 pm

1 stop27h 15m

$410

Kansas CitySanto Domingo

MCI - SDQ

MCISDQ

Kansas City

lun. 12/1

7:31 pm-3:30 pm

1 stop17h 59m

Santo Domingo Las Americas

lun. 12/8

6:10 am-11:06 pm

2 stops18h 56m

$421

St. LouisSantiago de los Caballeros

STL - STI

STLSTI

Lambert-St Louis

jue. 12/11

2:57 pm-2:42 am

1 stop9h 45m

Santiago de los Caballeros

lun. 12/15

3:43 am-10:33 pm

2 stops20h 50m

$441

St. LouisPunta Cana

STL - PUJ

STLPUJ

Lambert-St Louis

mar. 2/24

6:30 am-3:56 pm

1 stop7h 26m

Punta Cana

vie. 2/27

6:05 pm-9:04 am

1 stop16h 59m

$450

St. LouisPunta Cana

STL - PUJ

STLPUJ

Lambert-St Louis

dom. 2/8

7:30 am-3:25 pm

1 stop5h 55m

Punta Cana

mié. 2/11

4:50 pm-11:40 pm

1 stop8h 50m

$450

SpringfieldPunta Cana

SGF - PUJ

SGFPUJ

Springfield-Branson

jue. 1/29

5:39 pm-12:55 pm

1 stop17h 16m

Punta Cana

mar. 2/3

3:04 pm-9:00 pm

1 stop7h 56m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/20

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from Missouri to Dominican Republic

Have a flexible travel schedule? Discover the best time to fly to Dominican Republic from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to the Dominican Republic

What is the cheapest month to book a flight from Missouri to Dominican Republic?

Currently, May is the cheapest month in which you can book a flight from Missouri to Dominican Republic (average of $331). Flying from Missouri to Dominican Republic in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to DO?

Find hourly flight availability from Missouri to Dominican Republic. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 21, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Dominican Republic in the evening. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Missouri to Dominican Republic?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Dominican Republic. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Dominican Republic flight should consider departing on Tuesday at noon when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Dominican Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Dominican Republic flight route?

    The Missouri to Dominican Republic flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Dominican Republic?

    A quick flight from Missouri to Dominican Republic can take about 7h 26m. Spirit Airlines provides one of the quickest options available for as low as $450. Missouri and Dominican Republic are separated by a distance of 1918 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Dominican Republic one-way?

    The cheapest airlines for a one-way flight from Missouri to Dominican Republic are Spirit Airlines ($160), Frontier ($164), and American Airlines ($287).

  • Can I find deals for flights from Missouri to Dominican Republic that include hotel bookings?

    Yes. In addition to deals on Missouri to Dominican Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Dominican Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Dominican Republic.

  • Can I find deals for business class flights from Missouri to Dominican Republic?

    Yes. Cheapflights offers flight deals from Missouri to Dominican Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Dominican Republic?

    Currently, May is the cheapest month in which you can book a flight from Missouri to Dominican Republic (average of $331). Flying from Missouri to Dominican Republic in November is currently the most expensive (average of $408). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Dominican Republic

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Luis Munoz Marin Intl flights
Newark to Luis Munoz Marin Intl flights
Newark to Santo Domingo flights
John F Kennedy Intl to Santo Domingo flights
John F Kennedy Intl to Santiago de los Caballeros flights
Orlando to Luis Munoz Marin Intl flights
John F Kennedy Intl to Punta Cana flights
Dulles Intl to Luis Munoz Marin Intl flights
Philadelphia to Luis Munoz Marin Intl flights
LaGuardia to Luis Munoz Marin Intl flights
Newark to Punta Cana flights
Boston to Luis Munoz Marin Intl flights
Newark to Santiago de los Caballeros flights
John F Kennedy Intl to Montego Bay flights
Newark to Oranjestad flights
Atlanta to Luis Munoz Marin Intl flights
John F Kennedy Intl to Oranjestad flights
Dallas/Fort Worth to Luis Munoz Marin Intl flights
Reagan-National to Luis Munoz Marin Intl flights
Newark to Montego Bay flights
LaGuardia to Santo Domingo flights
O'Hare Intl to Luis Munoz Marin Intl flights
Boston to Oranjestad flights
Baltimore to Luis Munoz Marin Intl flights
O'Hare Intl to Punta Cana flights
Tampa to Luis Munoz Marin Intl flights
Boston to Santo Domingo flights
Fort Lauderdale to Luis Munoz Marin Intl flights
LaGuardia to Punta Cana flights
Hartford to Luis Munoz Marin Intl flights
Newark to Simpson Bay flights
John F Kennedy Intl to Port of Spain flights
Atlanta to Montego Bay flights
Newark to Nassau flights
Raleigh to Luis Munoz Marin Intl flights
Orlando to Punta Cana flights
Dulles Intl to Punta Cana flights
Miami to Santo Domingo flights
Miami to Luis Munoz Marin Intl flights
John F Kennedy Intl to Kingston flights
Detroit to Luis Munoz Marin Intl flights
Hobby to Luis Munoz Marin Intl flights
John F Kennedy Intl to Simpson Bay flights
Boston to Punta Cana flights
LaGuardia to Montego Bay flights
John F Kennedy Intl to Nassau flights
Fort Lauderdale to Santo Domingo flights
John F Kennedy Intl to Saint Thomas Island flights
George Bush Intcntl to Luis Munoz Marin Intl flights
Newark to Saint Thomas Island flights

Top 6 airlines flying from Missouri to Dominican Republic

Discover the top 6 airlines that operate flights from Missouri to Dominican Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$262Average$618FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$309Average$385FlexibilityNo cancel feeOn-time65%
FrontierCheapest$370Average$451FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$390Average$694FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$438Average$613FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$480Average$753FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.