$104+ Cheap flights from Panama City, FL to Detroit (ECP - DTT)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — DTT
Oct 15 — Oct 221
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Detroit with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Detroit
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Best
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Cheapest flights from Panama City to DetroitExplore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
Explore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2026.
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:10 am -
1 stop4h 43m
Tue 11/104:50 pm -
1 stop7h 02m
Deal found 9/14![American Airlines logo]()
$220
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:55 am -
1 stop3h 50m
Tue 11/106:00 am -
2 stops10h 35m
Deal found 9/14![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:10 pm -
1 stop4h 10m
Thu 12/106:00 am -
2 stops10h 35m
Deal found 9/14![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:41 pm -
1 stop4h 47m
Fri 11/65:40 pm -
1 stop7h 08m
Deal found 9/10![American Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:16 pm -
1 stop6h 41m
Thu 11/2612:30 pm -
1 stop6h 27m
Deal found 9/12![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop6h 04m
Thu 11/265:40 pm -
1 stop4h 52m
Deal found 9/12![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:16 pm -
1 stop6h 41m
Tue 12/16:15 pm -
1 stop6h 02m
Deal found 9/12![Delta logo]()
$376
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:42 pm -
1 stop4h 53m
Mon 10/121:49 pm -
1 stop5h 53m
Deal found 9/12![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:30 am -
2 stops9h 30m
Fri 11/61:30 pm -
2 stops9h 00m
Deal found 9/10![Southwest logo]()
$385
Best flights from Panama City to DetroitDiscover carefully curated flight deals from Panama City to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
Discover carefully curated flight deals from Panama City to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2026.
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:16 pm -
1 stop6h 41m
Thu 11/2612:30 pm -
1 stop6h 27m
Deal found 9/12![Delta logo]()
$348
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:58 pm -
1 stop7h 16m
Wed 12/98:41 am -
1 stop5h 36m
Deal found 9/10![United Airlines logo]()
$393
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:55 am -
1 stop4h 25m
Fri 11/61:30 pm -
2 stops9h 00m
Deal found 9/10![Southwest logo]()
$405
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
2 stops6h 55m
Sun 10/186:05 am -
1 stop4h 10m
Deal found 9/13![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:16 pm -
1 stop6h 41m
Thu 11/265:40 pm -
2 stops16h 29m
Deal found 9/12![Delta logo]()
$454
Last-minute flights from Panama City to DetroitDiscover last-minute flight deals from Panama City to Detroit. Data last updated September 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Detroit. Data last updated September 15, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
1 stop5h 55m
Wed 9/166:10 pm -
1 stop5h 55m
Deal found 9/14![Delta logo]()
$503
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/169:10 am -
2 stops10h 25m
Wed 9/2312:55 pm -
2 stops6h 55m
Deal found 9/13![Southwest logo]()
$513
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/242:50 pm -
1 stop6h 40m
Mon 9/286:15 am -
1 stop8h 48m
Deal found 9/10![United Airlines logo]()
$497
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:00 am -
1 stop4h 10m
Mon 9/281:20 pm -
2 stops6h 45m
Deal found 9/10![Southwest logo]()
$502
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:50 pm -
1 stop6h 41m
Tue 9/296:15 am -
1 stop8h 48m
Deal found 9/10![United Airlines logo]()
$490
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/284:10 pm -
1 stop5h 30m
Wed 9/306:00 am -
1 stop4h 40m
Deal found 9/11![Southwest logo]()
$510
This American Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/96:42 pm -
1 stop4h 53m
Mon 10/121:49 pm -
1 stop5h 53m
Deal found 9/12![American Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/94:00 pm -
1 stop5h 25m
Mon 10/122:45 pm -
2 stops7h 10m
Deal found 9/12![Southwest logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:42 pm -
1 stop4h 53m
Sun 10/186:10 am -
1 stop5h 18m
Deal found 9/13![American Airlines logo]()
$441
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:10 pm -
2 stops6h 55m
Sun 10/186:05 am -
1 stop4h 10m
Deal found 9/13![Southwest logo]()
$447
One-way flights from Panama City to DetroitSearch for one-way flight options from Panama City to Detroit. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
Search for one-way flight options from Panama City to Detroit. Find affordable one-way fares based on user searches. Data last updated September 15, 2026.
This Southwest deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/143:20 pm -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Southwest logo]()
$104
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:20 am -
2 stops10h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$172
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:46 pm -
1 stop4h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$229
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:30 pm -
1 stop5h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$252
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:19 pm -
1 stop4h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:20 am -
2 stops13h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:20 am -
2 stops10h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/11:32 pm -
2 stops9h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![American Airlines logo]()
$300
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:25 pm -
1 stop4h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Southwest logo]()
$326
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:41 am -
2 stops11h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![United Airlines logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/116:42 pm -
1 stop4h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![American Airlines logo]()
$375
Find flight deals from Panama City to Detroit
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Detroit (DTT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $220 (American Airlines) |
One-way from | $104 (Southwest) |
Popular in | February |
Cheapest in | November |
Average price | $348 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
Use the filters below to find and compare flights from Panama City to Detroit that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Mon 10/5
1:46 pm-7:04 pm
1 stop4h 18m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$229
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Fri 10/2
2:08 pm-8:40 pm
1 stop5h 32m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$259
Quickest round-trip
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Mon 11/30
6:25 pm-11:35 pm
1 stop4h 10m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$326
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Wed 11/25
5:16 pm-12:57 am
1 stop6h 41m
Detroit Metropolitan Wayne County
Thu 11/26
12:30 pm-5:57 pm
1 stop6h 27m
$348
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Mon 10/5
11:41 am-11:59 pm
2 stops11h 18m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$354
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Sun 10/11
6:42 pm-12:35 am
1 stop4h 53m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$375
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Sat 12/5
1:58 pm-10:14 pm
1 stop7h 16m
Detroit Metropolitan Wayne County
Wed 12/9
8:41 am-1:17 pm
1 stop5h 36m
$393
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Wed 11/4
7:55 am-1:20 pm
1 stop4h 25m
Detroit Metropolitan Wayne County
Fri 11/6
1:30 pm-9:30 pm
2 stops9h 00m
$405
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Sun 10/11
6:20 am-11:59 pm
2 stops16h 39m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$424
Panama CityDetroit
ECP Panama City NW Florida Beaches - DTW Detroit Metropolitan Wayne County
ECPDTW
Panama City NW Florida Beaches
Mon 11/30
1:38 pm-10:47 pm
1 stop8h 09m
Detroit Metropolitan Wayne County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$425
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Panama City to Detroit
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Detroit in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Detroit flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Detroit flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Detroit flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Detroit flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Detroit flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama City with our price prediction graph.
ECP-DTT
ECP-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Detroit
ECP-DTT
ECP-DTW
What is the cheapest month to book a flight from Panama City, Florida to Detroit?
Currently, January is the cheapest month in which you can book a flight from Panama City, Florida to Detroit (average of $339). Flying from Panama City, Florida to Detroit in February is currently the most expensive (average of $1,514). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Detroit
Get insights into the airlines that provide service to Detroit. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Detroit. Reviews last updated September 15, 2026.
Read reviews from past customers who have flown Delta from Panama City to Detroit. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Comfort
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Overall
7.8
Reviews
1 / 20
10.0
ExcellentSalvador,Aug 2026
PHL - DTW
Related info for your journey
Find useful and relevant information for your journey from Panama City to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Detroit?
Book flights to Detroit if you plan to visit one of these locationsRoseville
Port Huron
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Complete your trip to Detroit by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Detroit
Explore flights to Detroit departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
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Panama City and Detroit flights
Browse other Panama City and Detroit flight options. Last updated on September 15, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama City to Detroit flights
Consider these flights traveling from Panama City to Detroit.
Top 3 airlines flying from Panama City to Detroit
Discover the top 3 airlines that operate flights from Panama City to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$508 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$238 | Average$348 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$278 | Average$360 | FlexibilityNo cancel fee | On-time71% |