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Des Moines

$92+ Cheap flights from Tampa to Des Moines (TPA - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/27. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — DSM
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Tampa to Des Moines

Cheapest flights from Tampa to Des Moines
Explore the most affordable flight options available from Tampa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:38 am
TPA
-
DSM
1 stop8h 08m
American Airlines
Tue 4/212:16 pm
DSM
-
TPA
1 stop7h 17m
American Airlines
Deal found 3/18$237
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:20 pm
TPA
-
DSM
2 stops6h 50m
Southwest
Wed 4/295:30 am
DSM
-
TPA
2 stops7h 10m
Southwest
Deal found 3/19$247
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:20 am
TPA
-
DSM
1 stop8h 55m
Multiple Airlines
Sun 5/177:45 am
DSM
-
TPA
1 stop10h 16m
Multiple Airlines
Deal found 3/18$279
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:26 am
TPA
-
DSM
1 stop6h 42m
Delta
Tue 5/196:41 pm
DSM
-
TPA
1 stop4h 50m
Delta
Deal found 3/19$284
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:04 pm
TPA
-
DSM
2 stops23h 11m
Multiple Airlines
Sun 5/177:45 am
DSM
-
TPA
1 stop10h 16m
Multiple Airlines
Deal found 3/19$286
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:20 am
TPA
-
DSM
1 stop8h 55m
Multiple Airlines
Sun 5/107:45 am
DSM
-
TPA
1 stop10h 16m
Multiple Airlines
Deal found 3/18$287
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:14 am
TPA
-
DSM
1 stop14h 52m
Multiple Airlines
Sun 4/122:36 pm
DSM
-
TPA
1 stop6h 23m
Multiple Airlines
Deal found 3/18$294
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:04 pm
TPA
-
DSM
2 stops21h 27m
Multiple Airlines
Sun 5/177:45 am
DSM
-
TPA
1 stop10h 16m
Multiple Airlines
Deal found 3/19$295

Find flight deals from Tampa to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$237
(American Airlines)

One-way from

$92
(Kiwi.com)

Popular in

January

Cheapest in

September

Average price

$410

Good one-way deal

$106 or less
Provider with most accurate pricing for Tampa-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Tampa-Des Moines flights.
Search Deals
From Tampa to Des Moines
Search Deals
One-way flight from Tampa to Des Moines
Search Deals
Highest demand for flights based on searches. 35% potential increase in price ($266 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($34 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a one-way flight from Tampa to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Mon 5/11

7:02 am-12:24 pm

1 stop6h 22m

Des Moines

Tue 5/19

6:41 pm-12:31 am

1 stop4h 50m

$284

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 4/14

4:50 pm-11:17 pm

2 stops7h 27m

Des Moines

Tue 4/21

6:20 am-3:23 pm

2 stops8h 03m

$327

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Sat 5/9

8:50 am-1:37 pm

1 stop5h 47m

Des Moines

Sat 5/16

2:33 pm-9:01 pm

1 stop5h 28m

$331

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 5/20

3:55 pm-10:10 pm

1 stop7h 15m

Des Moines

Sat 5/30

5:35 am-12:50 pm

1 stop6h 15m

$332

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Sat 4/25

7:15 am-12:29 pm

1 stop6h 14m

Des Moines

Mon 4/27

6:20 am-3:23 pm

2 stops8h 03m

$336

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 4/22

5:07 pm-10:43 pm

1 stop6h 36m

Des Moines

Sat 4/25

6:20 am-2:46 pm

1 stop7h 26m

$364

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 4/14

4:33 pm-9:15 pm

1 stop5h 42m

Des Moines

Tue 4/21

1:38 pm-9:15 pm

1 stop6h 37m

$377

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 5/14

1:15 pm-8:21 pm

1 stop8h 06m

Des Moines

Mon 5/18

11:09 am-6:37 pm

1 stop6h 28m

$383

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 5/7

12:30 pm-9:55 pm

2 stops10h 25m

Des Moines

Sun 5/10

4:20 pm-12:05 am

2 stops6h 45m

$389
Cheapest one-way

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 6/2

4:20 pm-10:10 pm

2 stops6h 50m

$124

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/19

Showing 1-10 of 18 resultsSorted by cheapest first
1
2

Compare providers for flights from Tampa to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to Des Moines in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Tampa-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Tampa-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Tampa to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Des Moines

What is the cheapest month to book a flight from Tampa to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Tampa to Des Moines (average of $64). Flying from Tampa to Des Moines in February is currently the most expensive (average of $176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 22, 2026.
Read reviews from past customers who have flown Southwest,Delta, andAmerican Airlines from Tampa to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
8.0
Very good
4,324 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,314 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,487 reviews
Southwest
8.0
Very good
4,324 reviews

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Tampa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tampa to Des Moines?

    A quick flight from Tampa to Des Moines can take about 6h 22m. Delta provides one of the quickest options available for as low as $284. The distance from Tampa to Des Moines is about 1127 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Tampa to Des Moines round-trip?

    Our cheapest airline available from Tampa to Des Moines is Delta. Our recent data shows that you can find tickets from as low as $237 on this airline. Additional options worth looking into are American Airlines and Southwest, starting at $250 and $252 round-trip. Delta is priced at 51% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Tampa to Des Moines one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $118. Users have also found prices from $140 and $142 on American Airlines and Southwest, respectively.

  • Can I find deals for flights from Tampa to Des Moines that include hotel bookings?

    Yes. In addition to deals on Tampa to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Des Moines.

  • Can I find deals for business class flights from Tampa to Des Moines?

    Yes. Cheapflights offers flight deals from Tampa to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Tampa to Des Moines (average of $64). Flying from Tampa to Des Moines in February is currently the most expensive (average of $176). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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Top 3 airlines flying from Tampa to Des Moines

Discover the top 3 airlines that operate flights from Tampa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$237Average$333FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$369FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$252Average$425FlexibilityNo cancel feeOn-time63%

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