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Des Moines

$100+ Cheap flights from Tampa to Des Moines (TPA - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — DSM
Oct 22 — Oct 291
Wed 10/22
Wed 10/29
1 adult, Economy
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Cheap flight deals from Tampa to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 22, 2025.

Round-trip from

$170
(Booking.com)

One-way from

$100
(Trip.com)

Popular in

May

Cheapest in

July

Average price

$316

Good round-trip deal

$104 or less
From Tampa to Des Moines
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One-way flight from Tampa to Des Moines
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Highest demand for flights based on searches. 5% potential increase in price ($24 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Tampa to Des Moines.
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Find flight deals from Tampa to Des Moines

Cheapest flights from Tampa to Des Moines
Explore the most affordable flight options available from Tampa to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2025.

This Booking.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:50 pmTPA - DSM
1 stop16h 02mFrontier
Mon 10/132:39 pmDSM - TPA
1 stop13h 43mFrontier
Deal found 9/22$170
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:37 amTPA - DSM
1 stop8h 15mFrontier
Mon 10/272:39 pmDSM - TPA
1 stop13h 43mFrontier
Deal found 9/22$214
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2210:00 amTPA - DSM
1 stop4h 28mDelta
Mon 10/276:39 pmDSM - TPA
1 stop4h 38mDelta
Deal found 9/22$277
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:55 amTPA - DSM
2 stops6h 05mSouthwest
Mon 10/276:15 pmDSM - TPA
1 stop4h 20mSouthwest
Deal found 9/22$282
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:37 amTPA - DSM
1 stop8h 15mMultiple Airlines
Mon 10/278:30 amDSM - TPA
2 stops13h 56mMultiple Airlines
Deal found 9/22$291
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/46:25 amTPA - DSM
1 stop7h 09mAmerican Airlines
Sat 11/154:03 pmDSM - TPA
1 stop4h 56mAmerican Airlines
Deal found 9/20$294
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/910:50 pmTPA - DSM
1 stop16h 02mMultiple Airlines
Mon 10/135:51 pmDSM - TPA
2 stops12h 17mMultiple Airlines
Deal found 9/22$295
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:30 amTPA - DSM
2 stops11h 05mSouthwest
Sat 1/106:45 amDSM - TPA
1 stop4h 25mSouthwest
Deal found 9/20$299
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1911:15 amTPA - DSM
2 stops27h 37mMultiple Airlines
Sun 10/2610:41 amDSM - TPA
1 stop11h 45mMultiple Airlines
Deal found 9/21$335
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:28 amTPA - DSM
2 stops11h 31mMultiple Airlines
Mon 10/272:39 pmDSM - TPA
1 stop13h 43mMultiple Airlines
Deal found 9/22$351

Cheapflights Fare Finder

 
Customize your flight search to find flights from Tampa to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
Use the filters below to find and compare flights from Tampa to Des Moines that are best for you.

Fly from

Tampa

Fly to

Des Moines

Route

Depart

Return

Price

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 10/23

6:37 am-1:52 pm

1 stop8h 15m

Des Moines

Mon 10/27

2:39 pm-5:22 am

1 stop13h 43m

$214

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/22

10:00 am-1:28 pm

1 stop4h 28m

Des Moines

Mon 10/27

6:39 pm-12:17 am

1 stop4h 38m

$277

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/22

6:37 am-1:52 pm

1 stop8h 15m

Des Moines

Mon 10/27

8:30 am-11:26 pm

2 stops13h 56m

$291

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Tue 11/4

6:25 am-12:34 pm

1 stop7h 09m

Des Moines

Sat 11/15

4:03 pm-9:59 pm

1 stop4h 56m

$294

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 12/11

7:35 am-11:25 am

1 stop4h 50m

Des Moines

Sat 1/10

6:45 am-12:10 pm

1 stop4h 25m

$294

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Thu 10/9

10:50 pm-1:52 pm

1 stop16h 02m

Des Moines

Mon 10/13

5:51 pm-7:08 am

2 stops12h 17m

$295

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Sun 10/19

11:15 am-1:52 pm

2 stops27h 37m

Des Moines

Sun 10/26

10:41 am-11:26 pm

1 stop11h 45m

$335

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Fri 12/5

7:00 am-7:08 pm

1 stop13h 08m

$100

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 11/12

2:31 pm-1:47 pm

1 stop24h 16m

$117

TampaDes Moines

TPA - DSM

TPADSM

Tampa

Wed 10/29

11:06 am-9:51 am

1 stop23h 45m

$124

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/21

Showing 1-10 of 16 results
1
2

Best time to book a flight from Tampa to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Tampa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Tampa to Des Moines

What is the cheapest month to book a flight from Tampa to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Tampa to Des Moines (average of $336). Flying from Tampa to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TPA to DSM?

Find hourly flight availability from Tampa to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2025.

One of the essential ways to save on airfare from Tampa to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 22, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Tampa to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,971 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,166 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Crew

8.6

Food

7.0

Overall

8.0

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Tampa to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Tampa to Des Moines?

    A quick flight from Tampa to Des Moines can take about 4h 28m. Frontier provides one of the quickest options available for as low as $277. The distance from Tampa to Des Moines is about 1127 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Tampa to Des Moines round-trip?

    Our cheapest airline available from Tampa to Des Moines is Frontier. Our recent data shows that you can find tickets from as low as $86 on this airline. Additional options worth looking into are American Airlines and Delta, starting at $250 and $260 round-trip. Frontier is priced at 78% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Tampa to Des Moines that include hotel bookings?

    Yes. In addition to deals on Tampa to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Tampa to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Tampa to Des Moines.

  • Can I find deals for business class flights from Tampa to Des Moines?

    Yes. Cheapflights offers flight deals from Tampa to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Tampa to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Tampa to Des Moines (average of $336). Flying from Tampa to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Alternative routes for Tampa to Des Moines

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Top 4 airlines flying from Tampa to Des Moines

Discover the top 4 airlines that operate flights from Tampa to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 22, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$86Average$138FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$250Average$381FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$284Average$547FlexibilityNo cancel feeOn-time63%
DeltaCheapest$286Average$389FlexibilityNo cancel feeOn-timeN/A

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