How popular is this Santa Ana, California to Des Moines flight route?

The Santa Ana J. Wayne/Orange Cnty to Des Moines flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Santa Ana, California to Des Moines?

For as low as $307, United Airlines can have you in Des Moines from Santa Ana, California in 7h 28m. The distance from Santa Ana, California to Des Moines is about 1425 mi.

What are the cheapest airlines flying from Santa Ana, California to Des Moines round-trip?

Cheapflights users have booked flights from Santa Ana, California to Des Moines round-trip from $114. Other airlines that can offer you cheap pricing are United Airlines, from $243, and American Airlines, from $276. Allegiant Air is priced at 66% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Santa Ana, California to Des Moines one-way?

One-way options have recently been found by users for as low as $60 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $84 and United Airlines from $138 one-way.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the cheapest flights from Santa Ana, California to Des Moines?

While on average a flight from Santa Ana, California to Des Moines is generally $172, our data shows the cheapest flight currently is $92. When looking at the most popular route, (Santa Ana J. Wayne/Orange Cnty - Des Moines), you can expect to pay $153 for that flight.

What are the most popular airlines that fly from Santa Ana, California to Des Moines?

Allegiant Air, American Airlines and Southwest are the most popular airlines when flying from Santa Ana, California to Des Moines.

Most accurate provider : When it comes to deals on Santa Ana, California-Des Moines flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Santa Ana, California-Des Moines flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Santa Ana, California-Des Moines flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?

Yes. In addition to deals on Santa Ana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Santa Ana to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Des Moines.

Can I find deals for business class flights from Santa Ana to Des Moines?

Yes. Cheapflights offers flight deals from Santa Ana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$109+ Flights from Santa Ana, CA to Des Moines

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Cheap flight deals from Santa Ana to Des Moines

Cheapest flights from Santa Ana to Des Moines
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$299

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Fri 1/27:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$314

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Sun 1/411:50 amDSM - SNA

1 stop24h 26mMultiple Airlines

Deal found 12/25

$331

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Sun 1/47:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$347

Mon 12/298:16 pmSNA - DSM

1 stop17h 15mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$355

Sat 12/276:55 pmSNA - DSM

1 stop14h 05mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$376

Fri 12/269:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$380

Fri 12/269:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Fri 1/27:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$386

Sun 12/289:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$402

Sun 12/289:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Fri 1/27:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$406

Sat 12/276:55 pmSNA - DSM

1 stop14h 05mMultiple Airlines

Sun 1/411:50 amDSM - SNA

1 stop24h 26mMultiple Airlines

Deal found 12/25

$408

Best flights from Santa Ana to Des Moines
Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

Sun 2/89:37 amSNA - DSM

Nonstop3h 26mMultiple Airlines

Fri 2/207:17 pmDSM - SNA

1 stop18h 23mMultiple Airlines

Deal found 12/25

$193

Thu 1/157:00 amSNA - DSM

1 stop7h 28mUnited Airlines

Tue 1/203:04 pmDSM - SNA

1 stop8h 38mUnited Airlines

Deal found 12/25

$307

Thu 2/511:25 amSNA - DSM

2 stops7h 55mSouthwest

Mon 2/96:25 amDSM - SNA

2 stops8h 45mSouthwest

Deal found 12/23

$387

Fri 1/231:20 pmSNA - DSM

1 stop6h 04mDelta

Fri 1/3011:26 amDSM - SNA

1 stop10h 38mDelta

Deal found 12/24

$420

Wed 2/186:40 pmSNA - DSM

1 stop23h 27mUnited Airlines

Wed 2/252:59 pmDSM - SNA

1 stop8h 46mUnited Airlines

Deal found 12/24

$410

Tue 2/101:17 pmSNA - DSM

1 stop5h 17mUnited Airlines

Fri 2/133:24 pmDSM - SNA

1 stop9h 06mUnited Airlines

Deal found 12/25

$412

Wed 2/189:00 amSNA - DSM

2 stops11h 20mUnited Airlines

Sat 2/282:59 pmDSM - SNA

1 stop8h 46mUnited Airlines

Deal found 12/24

$413

Last-minute flights from Santa Ana to Des Moines
Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated December 26, 2025 and is based on user searches.

Fri 12/269:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$380

Sat 12/276:55 pmSNA - DSM

1 stop14h 05mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$376

Mon 12/298:16 pmSNA - DSM

1 stop17h 15mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$355

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Mon 1/512:46 pmDSM - SNA

1 stop8h 35mMultiple Airlines

Deal found 12/25

$299

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Fri 1/27:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$314

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mMultiple Airlines

Sun 1/411:50 amDSM - SNA

1 stop24h 26mMultiple Airlines

Deal found 12/25

$331

Tue 12/309:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Sun 1/47:00 amDSM - SNA

Nonstop3h 46mAllegiant Air

Deal found 12/25

$347

Thu 1/89:37 amSNA - DSM

Nonstop3h 26mAllegiant Air

Sun 1/117:00 amDSM - SNA

Nonstop3h 47mAllegiant Air

Deal found 12/24

$149

Thu 1/157:00 amSNA - DSM

1 stop7h 28mUnited Airlines

Tue 1/203:04 pmDSM - SNA

1 stop8h 38mUnited Airlines

Deal found 12/25

$307

Sun 1/259:37 amSNA - DSM

Nonstop3h 26mAllegiant Air

Sun 2/17:00 amDSM - SNA

Nonstop3h 47mAllegiant Air

Deal found 12/25

$109

One-way flights from Santa Ana to Des Moines
Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated December 26, 2025.

Thu 1/110:55 amSNA - DSM

1 stop7h 35mUnited Airlines

Deal found 12/25

$131

Fri 1/211:53 amSNA - DSM

1 stop5h 51mFrontier

Deal found 12/25

$190

Sun 12/289:36 amSNA - DSM

Nonstop3h 18mAllegiant Air

Deal found 12/25

$209

Tue 1/611:11 amSNA - DSM

3 stops56h 58mMultiple Airlines

Deal found 12/25

$236

Sun 12/287:57 pmSNA - DSM

1 stop13h 59mMultiple Airlines

Deal found 12/25

$289

Tue 1/611:45 amSNA - DSM

1 stop8h 44mDelta

Deal found 12/25

$414

Sat 1/311:52 amSNA - DSM

1 stop5h 52mFrontier

Deal found 12/25

$499

Thu 1/111:11 amSNA - DSM

3 stops25h 47mMultiple Airlines

Deal found 12/25

$640

Find flight deals from Santa Ana to Des Moines

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$109 (eDestinos)
Popular in	June
Cheapest in	September
Average price	$209
Good round-trip deal	$162 or less
Good one-way deal	$109 or less

Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Des Moines flights.

Search Deals

From Santa Ana J. Wayne/Orange Cnty to Des Moines

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($67 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Price to beat on a round-trip flight from Santa Ana J. Wayne/Orange Cnty to Des Moines.

Search Deals

Price to beat on a one-way flight from Santa Ana J. Wayne/Orange Cnty to Des Moines.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 2/8

9:37 am-3:03 pm

Nonstop3h 26m

Des Moines

Fri 2/20

7:17 pm-11:40 am

1 stop18h 23m

$193

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/15

7:00 am-4:28 pm

1 stop7h 28m

Des Moines

Tue 1/20

3:04 pm-9:42 pm

1 stop8h 38m

$307

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 2/5

11:25 am-9:20 pm

2 stops7h 55m

Des Moines

Mon 2/9

6:25 am-1:10 pm

2 stops8h 45m

$387

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Wed 2/18

6:40 pm-8:07 pm

1 stop23h 27m

Des Moines

Wed 2/25

2:59 pm-9:45 pm

1 stop8h 46m

$410

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Tue 2/10

1:17 pm-8:34 pm

1 stop5h 17m

Des Moines

Fri 2/13

3:24 pm-10:30 pm

1 stop9h 06m

$412

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Wed 2/18

9:00 am-10:20 pm

2 stops11h 20m

Des Moines

Sat 2/28

2:59 pm-9:45 pm

1 stop8h 46m

$413

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 1/23

1:20 pm-9:24 pm

1 stop6h 04m

Des Moines

Fri 1/30

11:26 am-8:04 pm

1 stop10h 38m

$420

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Thu 1/1

10:55 am-8:30 pm

1 stop7h 35m

$131

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Fri 1/2

11:53 am-7:44 pm

1 stop5h 51m

$190

Santa AnaDes Moines

SNA - DSM

SNADSM

Santa Ana J. Wayne/Orange Cnty

Sun 12/28

9:36 am-2:54 pm

Nonstop3h 18m

$209

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 14 results

Compare providers for flights from Santa Ana to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Des Moines in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Santa Ana, California-Des Moines flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Santa Ana, California-Des Moines flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Santa Ana, California-Des Moines flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Des Moines

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of $82). Flying from Santa Ana, California to Des Moines in July is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SNA to DSM?

A simple way to save on the total cost of your ticket is to fly from Santa Ana, California to Des Moines in the afternoon. If you’re flexible enough to do this you can expect to save up to 73% on your trip compared to booking a flight at noon.

Reviews of airlines servicing Des Moines

Read reviews from past customers who have flown Southwest, United Airlines, and American Airlines from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Southwest

8.0

Very good

4,258 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

United Airlines

7.4

Good

9,116 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

American Airlines

7.2

Good

11,065 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Allegiant Air

7.2

Good

702 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

10.0

Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

How popular is this Santa Ana, California to Des Moines flight route?
The Santa Ana J. Wayne/Orange Cnty to Des Moines flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Santa Ana, California to Des Moines?
For as low as $307, United Airlines can have you in Des Moines from Santa Ana, California in 7h 28m. The distance from Santa Ana, California to Des Moines is about 1425 mi.
What are the cheapest airlines flying from Santa Ana, California to Des Moines round-trip?
Cheapflights users have booked flights from Santa Ana, California to Des Moines round-trip from $114. Other airlines that can offer you cheap pricing are United Airlines, from $243, and American Airlines, from $276. Allegiant Air is priced at 66% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Santa Ana, California to Des Moines one-way?
One-way options have recently been found by users for as low as $60 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $84 and United Airlines from $138 one-way.
What are the cheapest flights from Santa Ana, California to Des Moines?
While on average a flight from Santa Ana, California to Des Moines is generally $172, our data shows the cheapest flight currently is $92. When looking at the most popular route, (Santa Ana J. Wayne/Orange Cnty - Des Moines), you can expect to pay $153 for that flight.
Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?
Yes. In addition to deals on Santa Ana to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santa Ana to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Des Moines.
Can I find deals for business class flights from Santa Ana to Des Moines?
Yes. Cheapflights offers flight deals from Santa Ana to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santa Ana, California to Des Moines?
Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Des Moines (average of $82). Flying from Santa Ana, California to Des Moines in July is currently the most expensive (average of $229). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Altoona

Johnston

Boone

Ames

Clive

West Des Moines

Ankeny

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Other flights to Des Moines

Top 4 airlines flying from Santa Ana to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$114	Average$194	FlexibilityNo cancel fee	On-time88%
American Airlines	Cheapest$276	Average$383	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$352	Average$449	FlexibilityNo cancel fee	On-time63%
United Airlines	Cheapest$446	Average$668	FlexibilityNo cancel fee	On-time69%

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$109+ Cheap flights from Santa Ana, CA to Des Moines (SNA - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Santa Ana to Des Moines with Cheapflights

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Cheap flight deals from Santa Ana to Des Moines

Cheapest flights from Santa Ana to Des MoinesExplore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Find flight deals from Santa Ana to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.

Compare providers for flights from Santa Ana to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Des Moines in December.

Best time to book a flight from Santa Ana to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Des Moines

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

What is the cheapest time of day to fly from SNA to DSM?

Reviews of airlines servicing Des Moines

Read reviews from past customers who have flown Southwest, United Airlines, and American Airlines from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Santa Ana, California to Des Moines flight route?

How long is the flight from Santa Ana, California to Des Moines?

What are the cheapest airlines flying from Santa Ana, California to Des Moines round-trip?

What are the cheapest airlines to fly from Santa Ana, California to Des Moines one-way?

What are the cheapest flights from Santa Ana, California to Des Moines?

Can I find deals for flights from Santa Ana to Des Moines that include hotel bookings?

How can I find direct flights from Santa Ana to Des Moines?

Can I find deals for business class flights from Santa Ana to Des Moines?

What is the cheapest month to book a flight from Santa Ana, California to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Santa Ana to Des Moines

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Top 4 airlines flying from Santa Ana to Des Moines

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Cheapest flights from Santa Ana to Des Moines
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.