$69+ Cheap flights from Santa Ana to Des Moines (SNA - DSM)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — DSM
Apr 25 — May 21
Round-trip
1 adult, Economy
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Cheapest flights from Santa Ana to Des MoinesExplore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
Explore the most affordable flight options available from Santa Ana to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/312:27 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Sun 9/610:00 am
DSM
- SNA
Nonstop3h 37m
Allegiant Air
Deal found 3/22![Allegiant Air logo]()
$167
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:32 am
SNA
- DSM
Nonstop3h 19m
Allegiant Air
Sun 5/248:00 am
DSM
- SNA
Nonstop3h 42m
Allegiant Air
Deal found 3/25![Allegiant Air logo]()
$202
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/239:23 am
SNA
- DSM
Nonstop3h 19m
Allegiant Air
Sun 7/267:00 am
DSM
- SNA
Nonstop3h 33m
Allegiant Air
Deal found 3/25![Allegiant Air logo]()
$206
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Fri 4/249:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 3/25![Allegiant Air logo]()
$207
This Booking.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Sun 5/248:00 am
DSM
- SNA
Nonstop3h 42m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$226
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Mon 4/279:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:30 am
SNA
- DSM
1 stop11h 14m
Multiple Airlines
Sun 5/3110:26 pm
DSM
- SNA
1 stop15h 53m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:30 am
SNA
- DSM
1 stop11h 14m
Multiple Airlines
Mon 6/19:17 pm
DSM
- SNA
1 stop20h 06m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:29 am
SNA
- DSM
1 stop23h 40m
Multiple Airlines
Fri 4/2410:14 pm
DSM
- SNA
1 stop21h 46m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:10 pm
SNA
- DSM
1 stop22h 42m
Multiple Airlines
Sun 5/248:00 am
DSM
- SNA
Nonstop3h 42m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:14 pm
SNA
- DSM
2 stops39h 17m
Multiple Airlines
Sun 5/248:00 am
DSM
- SNA
Nonstop3h 42m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$249
Best flights from Santa Ana to Des MoinesDiscover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
Discover carefully curated flight deals from Santa Ana to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 26, 2026.
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:40 pm
SNA
- DSM
1 stop6h 37m
United Airlines
Tue 4/281:32 pm
DSM
- SNA
1 stop6h 01m
United Airlines
Deal found 3/24![United Airlines logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Multiple Airlines
Fri 4/2410:14 pm
DSM
- SNA
1 stop21h 46m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:25 am
SNA
- DSM
2 stops7h 50m
Southwest
Tue 4/286:55 am
DSM
- SNA
2 stops8h 35m
Southwest
Deal found 3/24![Southwest logo]()
$383
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:10 pm
SNA
- DSM
1 stop6h 02m
Delta
Fri 4/244:23 pm
DSM
- SNA
1 stop6h 34m
Delta
Deal found 3/22![Delta logo]()
$467
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:45 am
SNA
- DSM
1 stop7h 30m
United Airlines
Tue 6/21:35 pm
DSM
- SNA
1 stop5h 55m
United Airlines
Deal found 3/25![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:40 am
SNA
- DSM
2 stops8h 15m
Southwest
Mon 6/14:20 pm
DSM
- SNA
2 stops8h 00m
Southwest
Deal found 3/25![Southwest logo]()
$408
This Kiwi.com deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:30 am
SNA
- DSM
2 stops13h 02m
Multiple Airlines
Sun 6/148:36 pm
DSM
- SNA
1 stop19h 52m
Multiple Airlines
Deal found 3/21![Multiple Airlines logo]()
$412
This Southwest deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:45 am
SNA
- DSM
1 stop7h 00m
Southwest
Sun 8/97:00 am
DSM
- SNA
2 stops9h 05m
Southwest
Deal found 3/21![Southwest logo]()
$462
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:40 pm
SNA
- DSM
1 stop6h 37m
United Airlines
Mon 4/205:17 pm
DSM
- SNA
1 stop6h 41m
United Airlines
Deal found 3/24![United Airlines logo]()
$467
Last-minute flights from Santa Ana to Des MoinesDiscover last-minute flight deals from Santa Ana to Des Moines. Data last updated March 26, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Des Moines. Data last updated March 26, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Fri 4/249:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 3/25![Allegiant Air logo]()
$207
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Mon 4/279:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$233
This Cheapflightsfares deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Fri 4/249:45 am
DSM
- SNA
Nonstop3h 51m
Allegiant Air
Deal found 3/21![Allegiant Air logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Multiple Airlines
Fri 4/2410:14 pm
DSM
- SNA
1 stop21h 46m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2012:41 pm
SNA
- DSM
Nonstop3h 17m
Multiple Airlines
Mon 4/278:15 pm
DSM
- SNA
1 stop20h 13m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$333
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:40 pm
SNA
- DSM
1 stop6h 37m
United Airlines
Tue 4/281:32 pm
DSM
- SNA
1 stop6h 01m
United Airlines
Deal found 3/24![United Airlines logo]()
$287
This American Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:27 pm
SNA
- DSM
2 stops8h 49m
American Airlines
Tue 4/286:00 am
DSM
- SNA
1 stop8h 38m
American Airlines
Deal found 3/24![American Airlines logo]()
$292
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:29 am
SNA
- DSM
1 stop23h 40m
Multiple Airlines
Fri 4/2410:14 pm
DSM
- SNA
1 stop21h 46m
Multiple Airlines
Deal found 3/25![Multiple Airlines logo]()
$238
One-way flights from Santa Ana to Des MoinesSearch for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
Search for one-way flight options from Santa Ana to Des Moines. Find affordable one-way fares based on user searches. Data last updated March 26, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 3/22![Allegiant Air logo]()
$69
This Priceline deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1312:19 pm
SNA
- DSM
1 stop4h 55m
Frontier
Deal found 3/22![Frontier logo]()
$80
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$99
This Gotogate deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$100
This Cheapflightsfares deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/1812:41 pm
SNA
- DSM
Nonstop3h 17m
Allegiant Air
Deal found 3/23![Allegiant Air logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:30 am
SNA
- DSM
1 stop8h 31m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:45 am
SNA
- DSM
1 stop12h 26m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:29 am
SNA
- DSM
1 stop23h 40m
Frontier
Deal found 3/24![Frontier logo]()
$135
This Booking.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2810:32 am
SNA
- DSM
Nonstop3h 19m
Allegiant Air
Deal found 3/25![Allegiant Air logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/43:23 pm
SNA
- DSM
1 stop27h 43m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$140
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:10 am
SNA
- DSM
1 stop8h 05m
Southwest
Deal found 3/22![Southwest logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:45 am
SNA
- DSM
1 stop28h 10m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$149
Find flight deals from Santa Ana to Des Moines
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $167 (Kiwi.com) |
One-way from | $69 (Cheapflightsfares) |
Popular in | July |
Cheapest in | January |
Average price | $421 |
Good round-trip deal | $196 or less |
Good one-way deal | $138 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
Use the filters below to find and compare flights from Santa Ana to Des Moines that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Tue 4/21
2:40 pm-11:17 pm
1 stop6h 37m
Des Moines
Tue 4/28
1:32 pm-5:33 pm
1 stop6h 01m
$287
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Mon 4/20
12:41 pm-5:58 pm
Nonstop3h 17m
Des Moines
Fri 4/24
10:14 pm-6:00 pm
1 stop21h 46m
$297
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
6:45 am-4:15 pm
1 stop7h 30m
Des Moines
Tue 6/2
1:35 pm-5:30 pm
1 stop5h 55m
$317
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Tue 4/21
11:25 am-9:15 pm
2 stops7h 50m
Des Moines
Tue 4/28
6:55 am-1:30 pm
2 stops8h 35m
$383
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Thu 5/28
11:40 am-9:55 pm
2 stops8h 15m
Des Moines
Mon 6/1
4:20 pm-10:20 pm
2 stops8h 00m
$408
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Mon 6/8
7:30 am-10:32 pm
2 stops13h 02m
Des Moines
Sun 6/14
8:36 pm-2:28 pm
1 stop19h 52m
$412
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Wed 8/5
8:45 am-5:45 pm
1 stop7h 00m
Des Moines
Sun 8/9
7:00 am-2:05 pm
2 stops9h 05m
$462
Quickest round-trip
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 4/17
1:10 pm-9:12 pm
1 stop6h 02m
Des Moines
Fri 4/24
4:23 pm-8:57 pm
1 stop6h 34m
$467
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Fri 4/17
2:40 pm-11:17 pm
1 stop6h 37m
Des Moines
Mon 4/20
5:17 pm-9:58 pm
1 stop6h 41m
$467
Cheapest one-way
Santa AnaDes Moines
SNA - DSM
SNADSM
Santa Ana J. Wayne/Orange Cnty
Thu 4/16
11:29 am-1:09 pm
1 stop23h 40m
$135
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Des Moines
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Des Moines in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana-Des Moines flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Des Moines
Have a flexible travel schedule? Discover the best time to fly to Des Moines from Santa Ana with our price prediction graph.
SNA-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Des Moines
What is the cheapest month to book a flight from Santa Ana to Des Moines?
Currently, May is the cheapest month in which you can book a flight from Santa Ana to Des Moines (average of $118). Flying from Santa Ana to Des Moines in July is currently the most expensive (average of $236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SNA to DSM?
Find hourly flight availability from Santa Ana to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 26, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Ana to Des Moines as you normally would.
Reviews of airlines servicing Des Moines
Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 26, 2026.
Read reviews from past customers who have flown United Airlines,Allegiant Air, andAmerican Airlines from Santa Ana to Des Moines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Crew
8.1
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Food
6.6
Crew
8.1
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Food
6.6
Crew
8.1
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Food
6.6
Crew
8.1
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Overall
7.4
Reviews
1 / 20
10.0
ExcellentKathy,Jun 2024
RDD - SFO
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Des Moines?
Book flights to Des Moines if you plan to visit one of these locationsAltoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines
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Other flights to Des Moines
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Santa Ana and Des Moines flights
Browse other Santa Ana and Des Moines flight options. Last updated on March 26, 2026.
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Top 3 airlines flying from Santa Ana to Des Moines
Discover the top 3 airlines that operate flights from Santa Ana to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$119 | Average$197 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$276 | Average$383 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$387 | Average$668 | FlexibilityNo cancel fee | On-time69% |