Wednesday flights are generally found to be more expensive for flights from Roanoke to Des Moines. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Des Moines.
A simple way to save on the total cost of your ticket is to fly from Roanoke to Des Moines in the morning. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight at noon.