How long is the flight from Philadelphia to Des Moines?

For as low as $297, Delta can have you in Des Moines from Philadelphia in 6h 38m. Airlines will cover a distance of 969 mi.

What are the cheapest airlines flying from Philadelphia to Des Moines round-trip?

Frontier, at $131, was found to be the cheapest airline from Philadelphia to Des Moines.Alternate airlines to your destination round-trip include United Airlines and Delta. Frontier is priced at 63% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Philadelphia to Des Moines one-way?

One-way options have recently been found by users for as low as $102 on Southwest. Other airlines that offer cheap prices include Delta from $118 and United Airlines from $133 one-way.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most reliable airlines from Philadelphia to Des Moines?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Philadelphia to Des Moines on time: American Airlines (68%), PSA Airlines (68%), Qatar Airways (58%).

What are the most popular airlines that fly from Philadelphia to Des Moines?

American Airlines, Delta and Southwest are the most popular airlines when flying from Philadelphia to Des Moines.

Most accurate provider : When it comes to deals on Philadelphia-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Philadelphia-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Philadelphia-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Philadelphia-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Philadelphia-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Philadelphia to Des Moines that include hotel bookings?

Yes. In addition to deals on Philadelphia to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Philadelphia to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Philadelphia to Des Moines.

Can I find deals for business class flights from Philadelphia to Des Moines?

Yes. Cheapflights offers flight deals from Philadelphia to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$100+ Flights from Philadelphia to Des Moines

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Philadelphia to Des Moines are usually found in October or September, booked 40 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Philadelphia to Des Moines

Cheapest flights from Philadelphia to Des Moines
Explore the most affordable flight options available from Philadelphia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Wed 12/245:00 pmPHL - DSM

1 stop5h 40mUnited Airlines

Tue 12/306:46 pmDSM - PHL

1 stop4h 59mUnited Airlines

Deal found 12/24

$280

Wed 12/316:05 amPHL - DSM

1 stop6h 23mDelta

Sat 1/35:55 pmDSM - PHL

1 stop5h 00mDelta

Deal found 12/25

$302

Sun 12/286:10 amPHL - DSM

1 stop5h 40mUnited Airlines

Tue 12/306:46 pmDSM - PHL

1 stop4h 59mUnited Airlines

Deal found 12/24

$337

Tue 12/306:00 amPHL - DSM

2 stops9h 19mUnited Airlines

Thu 1/811:30 amDSM - PHL

1 stop5h 04mUnited Airlines

Deal found 12/25

$395

Wed 12/312:50 pmPHL - DSM

2 stops10h 08mUnited Airlines

Sat 1/36:46 pmDSM - PHL

1 stop4h 59mUnited Airlines

Deal found 12/25

$432

Wed 12/245:00 pmPHL - DSM

1 stop5h 40mUnited Airlines

Fri 12/266:46 pmDSM - PHL

1 stop4h 59mUnited Airlines

Deal found 12/23

$449

Wed 12/2412:05 pmPHL - DSM

2 stops10h 30mSouthwest

Fri 12/266:50 pmDSM - PHL

1 stop4h 30mSouthwest

Deal found 12/23

$510

Wed 12/3111:40 amPHL - DSM

2 stops9h 15mSouthwest

Sat 1/35:40 amDSM - PHL

2 stops8h 20mSouthwest

Deal found 12/25

$532

Sun 12/285:40 amPHL - DSM

2 stops6h 20mSouthwest

Tue 12/305:30 amDSM - PHL

2 stops10h 00mSouthwest

Deal found 12/24

$559

Best flights from Philadelphia to Des Moines
Discover carefully curated flight deals from Philadelphia to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

Thu 2/56:00 amPHL - DSM

1 stop17h 46mMultiple Airlines

Sun 2/82:58 pmDSM - PHL

1 stop8h 46mMultiple Airlines

Deal found 12/24

$209

Mon 3/95:00 pmPHL - DSM

1 stop6h 38mDelta

Fri 3/1311:02 amDSM - PHL

1 stop5h 57mDelta

Deal found 12/23

$297

Tue 1/611:27 amPHL - DSM

1 stop5h 14mDelta

Wed 1/75:35 amDSM - PHL

1 stop6h 49mDelta

Deal found 12/24

$315

Wed 1/75:40 amPHL - DSM

1 stop5h 58mDelta

Wed 1/74:21 pmDSM - PHL

1 stop6h 35mDelta

Deal found 12/24

$315

Wed 1/710:30 amPHL - DSM

1 stop6h 58mDelta

Mon 1/1210:59 amDSM - PHL

1 stop5h 58mDelta

Deal found 12/24

$337

Tue 12/3011:33 amPHL - DSM

1 stop6h 08mDelta

Thu 1/810:59 amDSM - PHL

1 stop5h 58mDelta

Deal found 12/25

$337

Sat 1/106:00 amPHL - DSM

1 stop4h 36mDelta

Sun 1/115:16 pmDSM - PHL

1 stop6h 05mDelta

Deal found 12/24

$337

Tue 1/611:27 amPHL - DSM

1 stop5h 14mDelta

Thu 1/810:59 amDSM - PHL

1 stop5h 58mDelta

Deal found 12/24

$337

Mon 1/55:40 amPHL - DSM

1 stop7h 35mDelta

Wed 1/75:35 amDSM - PHL

1 stop6h 49mDelta

Deal found 12/24

$337

Sat 1/106:00 amPHL - DSM

1 stop5h 19mDelta

Mon 1/125:16 pmDSM - PHL

1 stop6h 05mDelta

Deal found 12/24

$337

Fri 1/96:15 amPHL - DSM

1 stop5h 04mDelta

Tue 1/1310:59 amDSM - PHL

1 stop5h 58mDelta

Deal found 12/24

$337

Last-minute flights from Philadelphia to Des Moines
Discover last-minute flight deals from Philadelphia to Des Moines. Data last updated December 26, 2025 and is based on user searches.

Wed 12/245:00 pmPHL - DSM

1 stop5h 40mUnited Airlines

Tue 12/306:46 pmDSM - PHL

1 stop4h 59mUnited Airlines

Deal found 12/24

$280

Wed 12/316:05 amPHL - DSM

1 stop6h 23mDelta

Sat 1/35:55 pmDSM - PHL

1 stop5h 00mDelta

Deal found 12/25

$302

Tue 1/611:27 amPHL - DSM

1 stop5h 14mDelta

Wed 1/75:35 amDSM - PHL

1 stop6h 49mDelta

Deal found 12/24

$315

Tue 1/64:59 pmPHL - DSM

1 stop6h 30mDelta

Sun 1/115:16 pmDSM - PHL

1 stop6h 05mDelta

Deal found 12/24

$337

Wed 1/78:54 pmPHL - DSM

2 stops26h 15mMultiple Airlines

Sun 1/112:58 pmDSM - PHL

1 stop16h 49mMultiple Airlines

Deal found 12/24

$222

Thu 1/86:00 amPHL - DSM

1 stop17h 46mMultiple Airlines

Sun 1/112:58 pmDSM - PHL

1 stop16h 49mMultiple Airlines

Deal found 12/24

$207

Thu 1/86:00 amPHL - DSM

1 stop17h 46mMultiple Airlines

Mon 1/1211:09 amDSM - PHL

2 stops23h 05mMultiple Airlines

Deal found 12/24

$224

Thu 1/86:00 amPHL - DSM

1 stop17h 46mMultiple Airlines

Fri 1/911:09 amDSM - PHL

2 stops20h 38mMultiple Airlines

Deal found 12/24

$250

Fri 1/97:15 amPHL - DSM

1 stop15h 06mMultiple Airlines

Sun 1/112:58 pmDSM - PHL

1 stop16h 49mMultiple Airlines

Deal found 12/24

$269

Fri 1/97:15 amPHL - DSM

1 stop15h 06mMultiple Airlines

Mon 1/1211:09 amDSM - PHL

2 stops23h 05mMultiple Airlines

Deal found 12/24

$286

One-way flights from Philadelphia to Des Moines
Search for one-way flight options from Philadelphia to Des Moines. Find affordable one-way fares based on user searches. Data last updated December 26, 2025.

Thu 1/228:20 amPHL - DSM

1 stop15h 26mMultiple Airlines

Deal found 12/24

$100

Wed 1/284:55 pmPHL - DSM

1 stop30h 51mMultiple Airlines

Deal found 12/25

$103

Wed 2/256:16 pmPHL - DSM

1 stop29h 50mMultiple Airlines

Deal found 12/24

$105

Wed 3/1110:38 pmPHL - DSM

1 stop12h 07mFrontier

Deal found 12/24

$106

Thu 2/265:47 pmPHL - DSM

1 stop26h 17mFrontier

Deal found 12/25

$112

Sat 1/245:40 amPHL - DSM

1 stop7h 35mDelta

Deal found 12/25

$123

Sun 1/258:45 amPHL - DSM

1 stop26h 34mMultiple Airlines

Deal found 12/25

$124

Find flight deals from Philadelphia to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$207 (Kiwi.com)
One-way from	$100 (Kiwi.com)
Popular in	June
Cheapest in	October
Average price	$355

Provider with most accurate pricing for Philadelphia-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Philadelphia-Des Moines flights.

Search Deals

From Philadelphia to Des Moines

Search Deals

One-way flight from Philadelphia to Des Moines

Search Deals

Highest demand for flights based on searches. 6% potential increase in price ($22 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Philadelphia to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Thu 2/5

6:00 am-10:46 pm

1 stop17h 46m

Des Moines

Sun 2/8

2:58 pm-12:44 am

1 stop8h 46m

$209

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Mon 3/9

5:00 pm-10:38 pm

1 stop6h 38m

Des Moines

Fri 3/13

11:02 am-5:59 pm

1 stop5h 57m

$297

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Tue 1/6

11:27 am-3:41 pm

1 stop5h 14m

Des Moines

Wed 1/7

5:35 am-1:24 pm

1 stop6h 49m

$315

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Wed 1/7

5:40 am-10:38 am

1 stop5h 58m

Des Moines

Wed 1/7

4:21 pm-11:56 pm

1 stop6h 35m

$315

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Wed 1/7

10:30 am-4:28 pm

1 stop6h 58m

Des Moines

Mon 1/12

10:59 am-5:57 pm

1 stop5h 58m

$337

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Tue 12/30

11:33 am-4:41 pm

1 stop6h 08m

Des Moines

Thu 1/8

10:59 am-5:57 pm

1 stop5h 58m

$337

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Sat 1/10

6:00 am-9:36 am

1 stop4h 36m

Des Moines

Sun 1/11

5:16 pm-12:21 am

1 stop6h 05m

$337

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Tue 1/6

11:27 am-3:41 pm

1 stop5h 14m

Des Moines

Thu 1/8

10:59 am-5:57 pm

1 stop5h 58m

$337

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Mon 1/5

5:40 am-12:15 pm

1 stop7h 35m

Des Moines

Wed 1/7

5:35 am-1:24 pm

1 stop6h 49m

$337

PhiladelphiaDes Moines

PHL - DSM

PHLDSM

Philadelphia

Sat 1/10

6:00 am-10:19 am

1 stop5h 19m

Des Moines

Mon 1/12

5:16 pm-12:21 am

1 stop6h 05m

$337

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 19 results

Compare providers for flights from Philadelphia to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Philadelphia to Des Moines in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Philadelphia-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Philadelphia-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Philadelphia-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Philadelphia-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Philadelphia-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Philadelphia to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Philadelphia with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Philadelphia to Des Moines

How far ahead should I book a flight from Philadelphia to Des Moines?

Booking 40 days in advance of your planned departure date is, on average, the best time to get cheap flights from Philadelphia to Des Moines. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Philadelphia to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Philadelphia to Des Moines (average of $83). Flying from Philadelphia to Des Moines in January is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PHL to DSM?

It’s optimal to fly from Philadelphia to Des Moines in the morning. By choosing this option you can save up to 38% on the cost of your flight, compared to a flight in the afternoon.

What is the cheapest day to fly from Philadelphia to Des Moines?

Travelers seeking maximum savings on their Philadelphia to Des Moines flight should consider departing on Monday at noon when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Des Moines

See what other customers who have flown with Southwest, Delta, and United Airlines from Philadelphia to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,258 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,018 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,116 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,068 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.8

Fair

3,071 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Philadelphia to Des Moines?
For as low as $297, Delta can have you in Des Moines from Philadelphia in 6h 38m. Airlines will cover a distance of 969 mi.
What are the cheapest airlines flying from Philadelphia to Des Moines round-trip?
Frontier, at $131, was found to be the cheapest airline from Philadelphia to Des Moines.Alternate airlines to your destination round-trip include United Airlines and Delta. Frontier is priced at 63% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Philadelphia to Des Moines one-way?
One-way options have recently been found by users for as low as $102 on Southwest. Other airlines that offer cheap prices include Delta from $118 and United Airlines from $133 one-way.
What are the most reliable airlines from Philadelphia to Des Moines?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Philadelphia to Des Moines on time: American Airlines (68%), PSA Airlines (68%), Qatar Airways (58%).
Can I find deals for flights from Philadelphia to Des Moines that include hotel bookings?
Yes. In addition to deals on Philadelphia to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Philadelphia to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Philadelphia to Des Moines.
Can I find deals for business class flights from Philadelphia to Des Moines?
Yes. Cheapflights offers flight deals from Philadelphia to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Philadelphia to Des Moines?
Currently, August is the cheapest month in which you can book a flight from Philadelphia to Des Moines (average of $83). Flying from Philadelphia to Des Moines in January is currently the most expensive (average of $256). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Altoona

Johnston

Boone

Ames

Clive

West Des Moines

Ankeny

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Other flights to Des Moines

Top 5 airlines flying from Philadelphia to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$208	Average$337	FlexibilityNo cancel fee	On-time69%
Frontier	Cheapest$214	Average$281	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$236	Average$315	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$251	Average$369	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$257	Average$356	FlexibilityNo cancel fee	On-time71%

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$100+ Cheap flights from Philadelphia to Des Moines (PHL - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Philadelphia to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Philadelphia to Des Moines are usually found in October or September, booked 40 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Philadelphia to Des Moines

Cheapest flights from Philadelphia to Des MoinesExplore the most affordable flight options available from Philadelphia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Explore the most affordable flight options available from Philadelphia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Find flight deals from Philadelphia to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Philadelphia to Des Moines that are best for you.

Compare providers for flights from Philadelphia to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Philadelphia to Des Moines in December.

Best time to book a flight from Philadelphia to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Philadelphia with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Philadelphia to Des Moines

How far ahead should I book a flight from Philadelphia to Des Moines?

What is the cheapest month to book a flight from Philadelphia to Des Moines?

What is the cheapest time of day to fly from PHL to DSM?

What is the cheapest day to fly from Philadelphia to Des Moines?

Reviews of airlines servicing Des Moines

See what other customers who have flown with Southwest, Delta, and United Airlines from Philadelphia to Des Moines have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Philadelphia to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Philadelphia to Des Moines?

What are the cheapest airlines flying from Philadelphia to Des Moines round-trip?

What are the cheapest airlines to fly from Philadelphia to Des Moines one-way?

What are the most reliable airlines from Philadelphia to Des Moines?

Can I find deals for flights from Philadelphia to Des Moines that include hotel bookings?

How can I find direct flights from Philadelphia to Des Moines?

Can I find deals for business class flights from Philadelphia to Des Moines?

What is the cheapest month to book a flight from Philadelphia to Des Moines?

Traveling to a place near Des Moines?

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Alternative routes for Philadelphia to Des Moines

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Top 5 airlines flying from Philadelphia to Des Moines

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Cheapest flights from Philadelphia to Des Moines
Explore the most affordable flight options available from Philadelphia to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.