What’s the fastest layover option from New Orleans to Des Moines?

Flights via St. Louis (STL) have the shortest average one-way travel time for 1-stop routes: 3h 57m.

Which airport typically offers the quickest layover for flights from New Orleans to Des Moines?

Flights via St. Louis (STL) offer the fastest connection on this route, with an average layover time of 1h 13m.

What’s the top layover airport for flights from New Orleans to Des Moines?

St. Louis (STL) – chosen by Cheapflights users on 60% of 1-stop itineraries from New Orleans to Des Moines on Cheapflights.

What’s the cheapest layover airport for flights from New Orleans to Des Moines?

St. Louis (STL) is the most affordable 1-stop option, with an average round-trip price of $312.

How long is the flight from New Orleans to Des Moines?

American Airlines and Delta can get you from New Orleans to Des Moines in just under 5h 05m. Your travel time can differ by up to 1h 27m. Airlines will cover a distance of 820 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

What are the cheapest airlines flying from New Orleans to Des Moines round-trip?

Flying on American Airlines is currently your cheapest option to Des Moines, with prices starting at $244. Additional round-trip tickets that might be worth considering are offered by Delta and Southwest, with the lowest prices starting at $296 and $312, respectively. These flights start at 41% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the most popular airlines that fly from New Orleans to Des Moines?

Consider American Airlines, Southwest or Delta when booking your flight. These represent the most popular airlines when flying from New Orleans to Des Moines.

Most accurate provider : When it comes to deals on New Orleans-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on New Orleans-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from New Orleans-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on New Orleans-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from New Orleans to Des Moines that include hotel bookings?

Yes. In addition to deals on New Orleans to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from New Orleans to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Des Moines.

Can I find deals for business class flights from New Orleans to Des Moines?

Yes. Cheapflights offers flight deals from New Orleans to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$104+ Cheap Flights from New Orleans to Des Moines

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Cheap flight deals from New Orleans to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$350 (American Airlines)
One-way from	$104 (Trip.com)
Popular in	March
Cheapest in	February
Average price	$372

Provider with most accurate pricing for New Orleans Louis Armstrong-Des Moines flight deals.

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Provider most trusted by Cheapflights users for New Orleans Louis Armstrong-Des Moines flights.

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From New Orleans Louis Armstrong to Des Moines

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One-way flight from New Orleans Louis Armstrong to Des Moines

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($80 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).

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Average for round-trip flights in October 2025

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Find flight deals from New Orleans to Des Moines

Cheapest flights from New Orleans to Des Moines
Explore the most affordable flight options available from New Orleans to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

mar. 12/235:30 amMSY - DSM

1 stop5h 17mAmerican Airlines

lun. 12/294:16 pmDSM - MSY

1 stop6h 49mAmerican Airlines

Deal found 10/27

$350

jue. 10/306:34 pmMSY - DSM

1 stop16h 41mMultiple Airlines

dom. 11/210:41 amDSM - MSY

1 stop21h 54mMultiple Airlines

Deal found 10/26

$365

mar. 11/1111:17 amMSY - DSM

1 stop6h 53mAmerican Airlines

sáb. 11/159:02 amDSM - MSY

1 stop7h 14mAmerican Airlines

Deal found 10/26

$447

mar. 11/112:20 pmMSY - DSM

1 stop7h 12mUnited Airlines

sáb. 11/155:45 amDSM - MSY

2 stops7h 24mUnited Airlines

Deal found 10/26

$452

mar. 12/237:20 pmMSY - DSM

3 stops26h 20mUnited Airlines

lun. 12/296:00 amDSM - MSY

1 stop7h 08mUnited Airlines

Deal found 10/26

$559

Best flights from New Orleans to Des Moines
Discover carefully curated flight deals from New Orleans to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated octubre 28, 2025.

mar. 12/236:16 amMSY - DSM

1 stop6h 32mAmerican Airlines

lun. 12/294:16 pmDSM - MSY

1 stop6h 49mAmerican Airlines

Deal found 10/26

$350

mar. 3/1011:25 amMSY - DSM

1 stop5h 05mDelta

mié. 3/1110:15 amDSM - MSY

1 stop6h 14mDelta

Deal found 10/25

$417

mar. 11/112:20 pmMSY - DSM

1 stop7h 12mUnited Airlines

sáb. 11/155:45 amDSM - MSY

2 stops7h 24mUnited Airlines

Deal found 10/26

$452

mar. 11/1111:17 amMSY - DSM

1 stop6h 53mAmerican Airlines

sáb. 11/159:02 amDSM - MSY

1 stop7h 14mAmerican Airlines

Deal found 10/26

$447

mar. 3/1012:48 pmMSY - DSM

2 stops9h 02mUnited Airlines

mié. 3/115:40 amDSM - MSY

1 stop6h 04mUnited Airlines

Deal found 10/25

$462

Last-minute flights from New Orleans to Des Moines
Discover last-minute flight deals from New Orleans to Des Moines. Data last updated octubre 28, 2025 and is based on user searches.

jue. 10/306:34 pmMSY - DSM

1 stop16h 41mMultiple Airlines

dom. 11/210:41 amDSM - MSY

1 stop21h 54mMultiple Airlines

Deal found 10/26

$365

jue. 10/3011:07 amMSY - DSM

1 stop10h 06mAmerican Airlines

sáb. 11/16:00 amDSM - MSY

1 stop15h 12mAmerican Airlines

Deal found 10/26

$790

jue. 10/303:35 pmMSY - DSM

2 stops7h 55mSouthwest

sáb. 11/16:20 amDSM - MSY

1 stop7h 30mSouthwest

Deal found 10/26

$836

vie. 10/319:55 amMSY - DSM

2 stops30h 41mMultiple Airlines

dom. 11/210:41 amDSM - MSY

1 stop21h 54mMultiple Airlines

Deal found 10/27

$633

vie. 10/319:00 amMSY - DSM

1 stop11h 40mAmerican Airlines

dom. 11/25:00 amDSM - MSY

1 stop9h 54mAmerican Airlines

Deal found 10/27

$743

mar. 11/1111:17 amMSY - DSM

1 stop6h 53mAmerican Airlines

sáb. 11/159:02 amDSM - MSY

1 stop7h 14mAmerican Airlines

Deal found 10/26

$447

mar. 11/112:20 pmMSY - DSM

1 stop7h 12mUnited Airlines

sáb. 11/155:45 amDSM - MSY

2 stops7h 24mUnited Airlines

Deal found 10/26

$452

One-way flights from New Orleans to Des Moines
Search for one-way flight options from New Orleans to Des Moines. Find affordable one-way fares based on user searches. Data last updated octubre 28, 2025.

mié. 11/1911:32 amMSY - DSM

1 stop20h 57mMultiple Airlines

Deal found 10/27

$104

jue. 11/2011:12 amMSY - DSM

1 stop10h 02mMultiple Airlines

Deal found 10/27

$117

mar. 11/183:21 pmMSY - DSM

3 stops54h 15mMultiple Airlines

Deal found 10/27

$154

mar. 11/1810:27 amMSY - DSM

1 stop6h 24mAmerican Airlines

Deal found 10/27

$159

mar. 11/187:00 amMSY - DSM

2 stops9h 07mUnited Airlines

Deal found 10/27

$164

dom. 12/213:29 pmMSY - DSM

1 stop28h 15mFrontier

Deal found 10/26

$177

dom. 12/215:22 pmMSY - DSM

2 stops21h 41mMultiple Airlines

Deal found 10/26

$190

mar. 11/2510:55 amMSY - DSM

2 stops7h 31mAmerican Airlines

Deal found 10/26

$195

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 12/23

6:16 am-12:48 pm

1 stop6h 32m

Des Moines

lun. 12/29

4:16 pm-11:05 pm

1 stop6h 49m

$350

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 3/10

11:25 am-4:30 pm

1 stop5h 05m

Des Moines

mié. 3/11

10:15 am-4:29 pm

1 stop6h 14m

$417

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 11/11

11:17 am-6:10 pm

1 stop6h 53m

Des Moines

sáb. 11/15

9:02 am-4:16 pm

1 stop7h 14m

$447

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 11/11

2:20 pm-9:32 pm

1 stop7h 12m

Des Moines

sáb. 11/15

5:45 am-1:09 pm

2 stops7h 24m

$452

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 3/10

12:48 pm-9:50 pm

2 stops9h 02m

Des Moines

mié. 3/11

5:40 am-11:44 am

1 stop6h 04m

$462

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mié. 11/19

11:32 am-8:29 am

1 stop20h 57m

$104

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

jue. 11/20

11:12 am-9:14 pm

1 stop10h 02m

$117

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 11/18

3:21 pm-9:36 pm

3 stops54h 15m

$154

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 11/18

10:27 am-4:51 pm

1 stop6h 24m

$159

New OrleansDes Moines

MSY - DSM

MSYDSM

New Orleans Louis Armstrong

mar. 11/25

10:27 am-4:41 pm

1 stop6h 14m

$159

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 13 results

Compare providers for flights from New Orleans to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Des Moines in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on New Orleans-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on New Orleans-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from New Orleans-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on New Orleans-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for New Orleans-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from New Orleans to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from New Orleans with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Des Moines

Prices

What is the cheapest month to book a flight from New Orleans to Des Moines?

Currently, August is the cheapest month in which you can book a flight from New Orleans to Des Moines (average of $143). Flying from New Orleans to Des Moines in March is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSY to DSM?

When flying from New Orleans to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 51% versus a flight in the afternoon.

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from New Orleans to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,240 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

7.9

Good

7,994 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,032 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How long is the flight from New Orleans to Des Moines?
American Airlines and Delta can get you from New Orleans to Des Moines in just under 5h 05m. Your travel time can differ by up to 1h 27m. Airlines will cover a distance of 820 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
What are the cheapest airlines flying from New Orleans to Des Moines round-trip?
Flying on American Airlines is currently your cheapest option to Des Moines, with prices starting at $244. Additional round-trip tickets that might be worth considering are offered by Delta and Southwest, with the lowest prices starting at $296 and $312, respectively. These flights start at 41% lower than the current average price 3 months from now.
Can I find deals for flights from New Orleans to Des Moines that include hotel bookings?
Yes. In addition to deals on New Orleans to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from New Orleans to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from New Orleans to Des Moines.
Can I find deals for business class flights from New Orleans to Des Moines?
Yes. Cheapflights offers flight deals from New Orleans to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from New Orleans to Des Moines?
Currently, August is the cheapest month in which you can book a flight from New Orleans to Des Moines (average of $143). Flying from New Orleans to Des Moines in March is currently the most expensive (average of $343). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Johnston

Altoona

Boone

Ames

West Des Moines

Ankeny

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Alternative routes for New Orleans to Des Moines

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Other flights to Des Moines

Top 3 airlines flying from New Orleans to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$244	Average$351	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$296	Average$386	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$312	Average$364	FlexibilityNo cancel fee	On-time63%

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$104+ Cheap flights from New Orleans to Des Moines (MSY - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from New Orleans to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from New Orleans to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from New Orleans to Des Moines

Cheapest flights from New Orleans to Des MoinesExplore the most affordable flight options available from New Orleans to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

Explore the most affordable flight options available from New Orleans to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from New Orleans to Des Moines that are best for you.

Compare providers for flights from New Orleans to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from New Orleans to Des Moines in October.

Best time to book a flight from New Orleans to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from New Orleans with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from New Orleans to Des Moines

What is the cheapest month to book a flight from New Orleans to Des Moines?

What is the cheapest time of day to fly from MSY to DSM?

What’s the top layover airport for flights from New Orleans to Des Moines?

What’s the fastest layover option from New Orleans to Des Moines?

What’s the fastest layover option from New Orleans to Des Moines?

Which airport typically offers the quickest layover for flights from New Orleans to Des Moines?

Reviews of airlines servicing Des Moines

Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from New Orleans to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from New Orleans to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from New Orleans to Des Moines?

What are the cheapest airlines flying from New Orleans to Des Moines round-trip?

Can I find deals for flights from New Orleans to Des Moines that include hotel bookings?

How can I find direct flights from New Orleans to Des Moines?

Can I find deals for business class flights from New Orleans to Des Moines?

What is the cheapest month to book a flight from New Orleans to Des Moines?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for New Orleans to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from New Orleans to Des Moines

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Cheapest flights from New Orleans to Des Moines
Explore the most affordable flight options available from New Orleans to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 28, 2025.