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Des Moines

$299+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Mar 10 — Mar 171
Tue 3/10
Tue 3/17
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 8, 2026.

This Delta deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:40 am
MEX
-
DSM
2 stops11h 37m
Delta
Mon 7/2710:55 am
DSM
-
MEX
2 stops11h 10m
Delta
Deal found 2/7$510
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/239:05 am
MEX
-
DSM
2 stops28h 17m
United Airlines
Mon 3/301:10 pm
DSM
-
MEX
2 stops11h 00m
United Airlines
Deal found 2/6$515
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:15 pm
MEX
-
DSM
1 stop20h 32m
American Airlines
Fri 4/176:00 am
DSM
-
MEX
1 stop7h 10m
American Airlines
Deal found 2/5$518
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:40 am
MEX
-
DSM
1 stop9h 34m
Multiple Airlines
Fri 4/1710:14 pm
DSM
-
MEX
2 stops24h 46m
Multiple Airlines
Deal found 2/5$524
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/138:10 am
MEX
-
DSM
1 stop10h 09m
Multiple Airlines
Mon 2/167:17 pm
DSM
-
MEX
1 stop21h 48m
Multiple Airlines
Deal found 2/4$526
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:35 am
MEX
-
DSM
2 stops13h 10m
Delta
Wed 4/16:55 am
DSM
-
MEX
1 stop6h 45m
Delta
Deal found 2/8$530
This American Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/2510:20 am
MEX
-
DSM
1 stop10h 39m
American Airlines
Wed 4/15:05 am
DSM
-
MEX
1 stop7h 50m
American Airlines
Deal found 2/8$531
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/238:10 am
MEX
-
DSM
1 stop10h 06m
Multiple Airlines
Mon 3/308:21 pm
DSM
-
MEX
2 stops24h 39m
Multiple Airlines
Deal found 2/6$535
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:30 am
MEX
-
DSM
2 stops13h 04m
United Airlines
Fri 4/175:30 am
DSM
-
MEX
2 stops13h 20m
United Airlines
Deal found 2/5$550
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/158:10 am
MEX
-
DSM
1 stop10h 22m
Multiple Airlines
Sun 2/229:00 am
DSM
-
MEX
2 stops21h 40m
Multiple Airlines
Deal found 2/5$569
This CheapOair deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/158:10 am
MEX
-
DSM
1 stop10h 22m
Frontier
Sun 2/227:45 pm
DSM
-
MEX
1 stop21h 20m
Frontier
Deal found 2/6$574

Find flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated February 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$510
(Delta)

One-way from

$299
(Frontier)

Popular in

April

Cheapest in

February

Average price

$484
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico City Federal District to Des Moines
Search Deals
One-way flight from Mexico City Federal District to Des Moines
Search Deals
Highest demand for flights based on searches. 19% potential increase in price ($146 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 8, 2026.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 7/20

4:40 am-10:31 pm

1 stop16h 51m

Des Moines

Mon 7/27

5:12 pm-8:35 am

2 stops16h 23m

$510

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 7/20

8:40 am-9:17 pm

2 stops11h 37m

Des Moines

Mon 7/27

10:55 am-9:05 pm

2 stops11h 10m

$510

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 3/23

8:10 am-7:16 pm

1 stop10h 06m

Des Moines

Mon 3/30

3:02 pm-8:05 pm

1 stop30h 03m

$515

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 3/23

9:05 am-2:22 pm

2 stops28h 17m

Des Moines

Mon 3/30

1:10 pm-11:10 pm

2 stops11h 00m

$515

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 4/10

5:15 pm-2:47 pm

1 stop20h 32m

Des Moines

Fri 4/17

6:00 am-12:10 pm

1 stop7h 10m

$518

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 4/10

8:40 am-7:14 pm

1 stop9h 34m

Des Moines

Fri 4/17

10:14 pm-10:00 pm

2 stops24h 46m

$524

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 3/25

6:35 am-8:45 pm

2 stops13h 10m

Des Moines

Wed 4/1

6:55 am-12:40 pm

1 stop6h 45m

$530

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 3/25

10:20 am-9:59 pm

1 stop10h 39m

Des Moines

Wed 4/1

5:05 am-11:55 am

1 stop7h 50m

$531

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 3/23

8:10 am-7:16 pm

1 stop10h 06m

$299

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 3/23

10:50 pm-7:16 pm

3 stops43h 26m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/5

Showing 1-10 of 11 results
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Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines

What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in April is currently the most expensive (average of $1,072). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $510, United Airlines can have you in Des Moines from Mexico City Federal District in 11h 37m. There are 1559 mi between Mexico City Federal District and Des Moines. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in April is currently the most expensive (average of $1,072). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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