HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$321+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Jan 10 — Jan 171
Sat 1/10
Sat 1/17
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mexico City Federal District to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 11, 2025.

This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:40 amMEX - DSM
1 stop9h 07mDelta
Sat 1/316:54 amDSM - MEX
1 stop6h 46mDelta
Deal found 12/9$597
This United Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:45 amMEX - DSM
1 stop16h 45mUnited Airlines
Sat 1/319:03 amDSM - MEX
1 stop13h 27mUnited Airlines
Deal found 12/9$627
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 amMEX - DSM
1 stop11h 09mAmerican Airlines
Sat 1/3111:35 amDSM - MEX
1 stop11h 45mAmerican Airlines
Deal found 12/9$632
This Aeromexico deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:55 amMEX - DSM
2 stops9h 49mAeromexico
Sat 1/316:54 amDSM - MEX
1 stop6h 46mAeromexico
Deal found 12/8$659

Find flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated December 11, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$484
(United Airlines)

One-way from

$321
(United Airlines)

Popular in

October

Cheapest in

February

Average price

$645
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico City Federal District to Des Moines
Search Deals
One-way flight from Mexico City Federal District to Des Moines
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 11, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 1/22

10:10 am-10:09 pm

1 stop11h 59m

Des Moines

Thu 1/29

7:00 am-8:05 pm

2 stops37h 05m

$477

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 2/26

7:50 am-11:43 pm

2 stops15h 53m

Des Moines

Mon 3/2

9:04 am-12:10 am

2 stops15h 06m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 1/22

9:05 am-11:44 pm

1 stop14h 39m

Des Moines

Thu 1/29

1:35 pm-10:30 pm

1 stop8h 55m

$495

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 4/1

4:40 pm-2:26 pm

2 stops20h 46m

$321

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 4/1

3:15 pm-11:42 pm

1 stop7h 27m

$325

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 4/1

6:20 am-1:46 pm

3 stops30h 26m

$344

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 1/4

7:25 am-7:44 pm

3 stops36h 19m

$519

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 1/2

10:40 pm-11:00 am

2 stops36h 20m

$584

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 1/4

5:45 pm-2:19 pm

1 stop20h 34m

$825

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines

What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $484, United Airlines can have you in Des Moines from Mexico City Federal District in 15h 53m. There are 1559 mi between Mexico City Federal District and Des Moines.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2025 Cheapflights