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Des Moines

$238+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Find flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/275:45 amMEX - DSM
1 stop8h 36mUnited Airlines
Mon 12/111:26 amDSM - MEX
2 stops12h 44mUnited Airlines
Deal found 11/17$561
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:02 amMEX - DSM
1 stop7h 55mAmerican Airlines
Sat 1/3111:35 amDSM - MEX
1 stop8h 01mAmerican Airlines
Deal found 11/19$576
This Aeromexico deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:00 pmMEX - DSM
2 stops26h 31mAeromexico
Sat 1/311:03 pmDSM - MEX
1 stop7h 47mAeromexico
Deal found 11/19$584
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/215:45 amMEX - DSM
1 stop16h 45mUnited Airlines
Sat 1/313:04 pmDSM - MEX
1 stop9h 06mUnited Airlines
Deal found 11/18$597
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:10 amMEX - DSM
1 stop11h 14mMultiple Airlines
Sun 11/3012:51 pmDSM - MEX
1 stop31h 14mMultiple Airlines
Deal found 11/17$599
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/195:45 pmMEX - DSM
2 stops20h 48mUnited Airlines
Sat 1/319:03 amDSM - MEX
1 stop13h 27mUnited Airlines
Deal found 11/18$608
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/239:05 amMEX - DSM
1 stop11h 40mUnited Airlines
Sun 11/309:44 pmDSM - MEX
2 stops14h 31mUnited Airlines
Deal found 11/18$622
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:20 pmMEX - DSM
1 stop17h 55mAmerican Airlines
Sat 1/3111:35 amDSM - MEX
1 stop11h 45mAmerican Airlines
Deal found 11/19$623

Cheap flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$483
(Delta)

One-way from

$238
(Kiwi.com)

Popular in

November

Cheapest in

June

Average price

$721
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
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From Mexico City Federal District to Des Moines
Search Deals
One-way flight from Mexico City Federal District to Des Moines
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($120 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

2:10 pm-10:31 pm

1 stop8h 21m

Des Moines

Mon 3/9

5:15 pm-10:20 am

1 stop18h 05m

$483

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 5/5

1:05 pm-10:29 pm

1 stop8h 24m

Des Moines

Tue 5/19

5:45 am-6:21 pm

1 stop13h 36m

$483

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 2/13

12:40 pm-10:31 pm

1 stop9h 51m

Des Moines

Tue 2/17

5:24 am-3:15 pm

1 stop9h 51m

$503

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

10:05 am-11:42 pm

2 stops13h 37m

Des Moines

Mon 3/9

8:00 am-5:55 pm

2 stops10h 55m

$554

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 12/21

10:00 pm-10:31 pm

2 stops24h 31m

Des Moines

Sat 1/31

6:54 am-1:40 pm

1 stop6h 46m

$584

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/14

11:00 am-3:40 pm

1 stop28h 40m

$246

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/7

11:55 am-10:09 pm

2 stops34h 14m

$272

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 12/22

8:10 am-7:44 pm

1 stop11h 34m

$294

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 1/5

11:55 am-7:44 pm

1 stop7h 49m

$331

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 1/6

8:10 am-1:50 pm

2 stops29h 40m

$357

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 13 results
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Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $483, Delta can have you in Des Moines from Mexico City Federal District in 8h 21m. There are 1559 mi between Mexico City Federal District and Des Moines.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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