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Des Moines

$288+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:40 amMEX - DSM
1 stop13h 21mDelta
Sat 1/316:54 amDSM - MEX
1 stop6h 46mDelta
Deal found 12/17$606
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 amMEX - DSM
1 stop10h 10mDelta
Fri 1/26:30 pmDSM - MEX
2 stops14h 35mDelta
Deal found 12/16$739
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:45 pmMEX - DSM
2 stops20h 48mUnited Airlines
Fri 1/28:00 amDSM - MEX
2 stops16h 10mUnited Airlines
Deal found 12/16$744

Find flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$488
(United Airlines)

One-way from

$288
(SmartFares)

Popular in

October

Cheapest in

February

Average price

$645
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
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From Mexico City Federal District to Des Moines
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One-way flight from Mexico City Federal District to Des Moines
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Highest demand for flights based on searches. 7% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 2/26

7:50 am-10:20 pm

1 stop14h 30m

Des Moines

Mon 3/2

8:08 am-6:55 pm

1 stop10h 47m

$488

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 1/9

5:45 pm-10:55 am

2 stops17h 10m

Des Moines

Sat 1/24

3:04 pm-12:10 am

1 stop9h 06m

$571

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 2/26

7:00 am-10:28 pm

2 stops15h 28m

Des Moines

Mon 3/2

5:24 am-7:05 pm

2 stops13h 41m

$684

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 12/30

7:05 am-5:15 pm

1 stop10h 10m

Des Moines

Fri 1/2

6:30 pm-9:05 am

2 stops14h 35m

$739

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Tue 12/30

5:45 pm-2:33 pm

2 stops20h 48m

Des Moines

Fri 1/2

8:00 am-12:10 am

2 stops16h 10m

$744

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 6/1

10:50 pm-8:45 pm

2 stops20h 55m

$288

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/31

8:01 am-8:45 pm

2 stops11h 44m

$308

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Mon 6/1

1:20 pm-11:22 pm

1 stop9h 02m

$348

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 12/28

5:45 am-6:05 pm

2 stops12h 20m

$390

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Sun 5/31

6:30 am-10:45 pm

3 stops15h 15m

$1,749

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 11 results
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Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines

What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mexico City Federal District to Des Moines?

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $488, United Airlines can have you in Des Moines from Mexico City Federal District in 14h 30m. There are 1559 mi between Mexico City Federal District and Des Moines.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

    Currently, June is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $478). Flying from Mexico City Federal District to Des Moines in November is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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