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Des Moines

$277+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated September 16, 2025.

Round-trip from

$504
(United Airlines)

One-way from

$277
(Kiwi.com)

Popular in

December

Cheapest in

June

Average price

$521
From Mexico City Federal District to Des Moines
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One-way flight from Mexico City Federal District to Des Moines
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Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:00 pmMEX - DSM
1 stop7h 13mAmerican Airlines
Fri 10/103:48 pmDSM - MEX
1 stop5h 57mAmerican Airlines
Deal found 9/16$702
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:30 amMEX - DSM
2 stops12h 07mDelta
Fri 10/1011:06 amDSM - MEX
2 stops11h 44mDelta
Deal found 9/16$728
This FlightHub deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2512:15 amMEX - DSM
2 stops20h 35mAir Canada
Fri 10/108:00 amDSM - MEX
2 stops16h 15mAir Canada
Deal found 9/16$1,894

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

8:40 am-4:30 pm

1 stop7h 50m

Des Moines

Mon 3/9

5:15 pm-10:20 am

1 stop18h 05m

$504

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

9:05 am-4:14 pm

1 stop7h 09m

Des Moines

Mon 3/9

1:45 pm-11:10 pm

2 stops10h 25m

$504

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 9/26

3:00 pm-11:13 pm

1 stop7h 13m

Des Moines

Fri 10/10

3:48 pm-8:45 pm

1 stop5h 57m

$702

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 9/26

9:30 am-10:37 pm

2 stops12h 07m

Des Moines

Fri 10/10

11:06 am-9:50 pm

2 stops11h 44m

$728

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 3/4

1:05 am-2:11 pm

2 stops13h 06m

Des Moines

Mon 3/9

6:45 pm-11:30 am

2 stops17h 45m

$2,276

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 10/3

11:45 am-10:37 pm

1 stop9h 52m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines

What is the cheapest time of day to fly from DF to DSM?

Find hourly flight availability from Mexico City Federal District to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mexico City Federal District to Des Moines as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $504, Delta can have you in Des Moines from Mexico City Federal District in 7h 09m. There are 1559 mi between Mexico City Federal District and Des Moines. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City Federal District to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Mexico City Federal District to Des Moines (average of $336). Flying from Mexico City Federal District to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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