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Des Moines

$260+ Cheap flights from Mexico City Federal District to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — DSM
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Mexico City Federal District to Des Moines

Cheapest flights from Mexico City Federal District to Des Moines
Explore the most affordable flight options available from Mexico City Federal District to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amMEX - DSM
2 stops15h 55mUnited Airlines
Wed 1/73:04 pmDSM - MEX
1 stop9h 06mUnited Airlines
Deal found 10/29$484
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:45 amMEX - DSM
2 stops15h 55mUnited Airlines
Mon 1/56:46 pmDSM - MEX
1 stop18h 49mUnited Airlines
Deal found 10/29$516
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amMEX - DSM
1 stop6h 24mAmerican Airlines
Mon 1/56:52 pmDSM - MEX
1 stop18h 28mAmerican Airlines
Deal found 10/29$576
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:05 amMEX - DSM
2 stops10h 40mUnited Airlines
Sat 11/152:52 pmDSM - MEX
1 stop9h 18mUnited Airlines
Deal found 10/29$581
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/210:05 amMEX - DSM
2 stops10h 40mUnited Airlines
Sat 11/86:05 amDSM - MEX
1 stop12h 50mUnited Airlines
Deal found 10/29$602
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:35 amMEX - DSM
2 stops12h 55mDelta
Sat 11/86:05 amDSM - MEX
2 stops14h 25mDelta
Deal found 10/28$603
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:05 amMEX - DSM
2 stops12h 49mMultiple Airlines
Mon 1/512:46 pmDSM - MEX
2 stops16h 39mMultiple Airlines
Deal found 10/29$1,099
This Booking.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:05 amMEX - DSM
2 stops13h 14mAir Canada
Sat 11/151:05 pmDSM - MEX
2 stops11h 45mAir Canada
Deal found 10/29$1,101
This Mytrip deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/301:05 amMEX - DSM
2 stops20h 35mAir Canada
Wed 1/76:48 pmDSM - MEX
2 stops17h 42mAir Canada
Deal found 10/29$1,309
This Booking.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/301:05 amMEX - DSM
2 stops32h 37mAir Canada
Sat 11/88:02 amDSM - MEX
2 stops40h 48mAir Canada
Deal found 10/28$1,690

Cheap flight deals from Mexico City Federal District to Des Moines

Keep the following information in mind while searching for Mexico City Federal District to Des Moines flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$484
(Delta)

One-way from

$260
(Kiwi.com)

Popular in

October

Cheapest in

June

Average price

$677
Provider with most accurate pricing for Mexico City Benito Juarez-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Mexico City Benito Juarez-Des Moines flights.
Search Deals
From Mexico City Federal District to Des Moines
Search Deals
One-way flight from Mexico City Federal District to Des Moines
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($28 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City Federal District to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mexico City Federal District to Des Moines that are best for you.

Fly from

Mexico City Federal District

Fly to

Des Moines

Route

Depart

Return

Price

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

2:40 pm-9:50 pm

1 stop7h 10m

Des Moines

Mon 3/9

3:00 pm-9:05 am

1 stop19h 05m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 3/5

6:40 am-4:56 pm

2 stops10h 16m

Des Moines

Mon 3/9

10:55 am-10:35 pm

2 stops12h 40m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 1/28

5:45 am-8:34 pm

2 stops14h 49m

Des Moines

Wed 2/11

8:00 am-4:45 pm

2 stops8h 45m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 12/31

5:45 am-9:40 pm

2 stops15h 55m

Des Moines

Wed 1/7

8:00 am-12:10 am

2 stops16h 10m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 12/31

5:45 am-9:40 pm

2 stops15h 55m

Des Moines

Mon 1/5

11:35 am-10:05 am

2 stops22h 30m

$484

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 12/11

11:55 am-6:38 pm

1 stop30h 43m

$260

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Wed 12/31

5:45 am-9:40 pm

2 stops15h 55m

$321

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Fri 1/2

6:20 am-7:44 pm

2 stops37h 24m

$402

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 1/1

5:45 am-10:30 pm

1 stop16h 45m

$426

Mexico CityDes Moines

MEX - DSM

MEXDSM

Mexico City Benito Juarez

Thu 1/1

6:20 am-2:58 pm

3 stops32h 38m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 11 results
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Best time to book a flight from Mexico City Federal District to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Mexico City Federal District with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City Federal District to Des Moines
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mexico City Federal District to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Mexico City Federal District?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Mexico City Federal District to Des Moines.

  • How long is the flight from Mexico City Federal District to Des Moines?

    For as low as $484, United Airlines can have you in Des Moines from Mexico City Federal District in 7h 10m. There are 1559 mi between Mexico City Federal District and Des Moines. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Mexico City Federal District to Des Moines that include hotel bookings?

    Yes. In addition to deals on Mexico City Federal District to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City Federal District to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City Federal District to Des Moines.

  • Can I find deals for business class flights from Mexico City Federal District to Des Moines?

    Yes. Cheapflights offers flight deals from Mexico City Federal District to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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