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Des Moines

$65+ Cheap flights from Memphis to Des Moines (MEM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
dic. 6 — dic. 131
sáb. 12/6
sáb. 12/13
1 adult, Economy
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Find flight deals from Memphis to Des Moines

Cheapest flights from Memphis to Des Moines
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/199:33 pmMEM - DSM
1 stop17h 54mMultiple Airlines
dom. 11/238:19 pmDSM - MEM
1 stop22h 45mMultiple Airlines
Deal found 11/4$270
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/235:12 amMEM - DSM
1 stop5h 35mAmerican Airlines
sáb. 12/276:57 pmDSM - MEM
1 stop5h 02mAmerican Airlines
Deal found 11/5$289
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/238:38 pmMEM - DSM
1 stop25h 03mMultiple Airlines
lun. 12/16:53 pmDSM - MEM
2 stops38h 09mMultiple Airlines
Deal found 11/5$295
This American Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/128:49 amMEM - DSM
1 stop7h 40mAmerican Airlines
dom. 12/142:08 pmDSM - MEM
1 stop5h 35mAmerican Airlines
Deal found 11/6$327
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/123:16 pmMEM - DSM
1 stop18h 32mMultiple Airlines
dom. 12/144:21 pmDSM - MEM
2 stops28h 06mMultiple Airlines
Deal found 11/5$335
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/122:20 pmMEM - DSM
2 stops9h 15mSouthwest
dom. 12/145:45 amDSM - MEM
2 stops7h 55mSouthwest
Deal found 11/5$347
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/123:25 pmMEM - DSM
1 stop5h 23mUnited Airlines
dom. 12/1411:35 amDSM - MEM
2 stops10h 46mUnited Airlines
Deal found 11/6$392
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/231:30 pmMEM - DSM
2 stops10h 35mSouthwest
sáb. 12/276:45 pmDSM - MEM
2 stops14h 50mSouthwest
Deal found 11/5$398
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/232:20 pmMEM - DSM
2 stops9h 15mSouthwest
lun. 12/16:35 amDSM - MEM
2 stops12h 55mSouthwest
Deal found 11/5$429

Cheap flight deals from Memphis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated noviembre 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$65
(Trip.com)

Popular in

November

Cheapest in

May

Average price

$882
Provider with most accurate pricing for Memphis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Memphis-Des Moines flights.
Search Deals
From Memphis to Des Moines
Search Deals
One-way flight from Memphis to Des Moines
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($173 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($48 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Memphis

Fly to

Des Moines

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar. 12/23

5:12 am-10:47 am

1 stop5h 35m

Des Moines

sáb. 12/27

6:57 pm-11:59 pm

1 stop5h 02m

$289

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar. 1/20

3:20 pm-9:50 pm

1 stop6h 30m

Des Moines

vie. 1/23

3:35 pm-9:59 pm

1 stop6h 24m

$289

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar. 1/20

8:15 am-7:20 pm

2 stops11h 05m

Des Moines

vie. 1/23

12:05 pm-7:55 pm

1 stop7h 50m

$294

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

sáb. 3/7

5:00 am-1:16 pm

1 stop8h 16m

Des Moines

mié. 3/11

1:05 pm-9:28 pm

1 stop8h 23m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

vie. 12/12

8:49 am-4:29 pm

1 stop7h 40m

Des Moines

dom. 12/14

6:28 pm-11:59 pm

1 stop5h 31m

$327

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

vie. 12/12

3:16 pm-9:48 am

1 stop18h 32m

Des Moines

dom. 12/14

4:21 pm-8:27 pm

2 stops28h 06m

$335

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

vie. 12/12

2:20 pm-11:35 pm

2 stops9h 15m

Des Moines

dom. 12/14

5:45 am-1:40 pm

2 stops7h 55m

$347

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

vie. 12/12

3:25 pm-8:48 pm

1 stop5h 23m

Des Moines

dom. 12/14

11:35 am-10:21 pm

2 stops10h 46m

$392

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

lun. 3/9

4:25 pm-11:15 pm

1 stop6h 50m

Des Moines

dom. 3/15

4:40 pm-11:25 pm

1 stop6h 45m

$397

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

mar. 12/23

1:30 pm-12:05 am

2 stops10h 35m

Des Moines

sáb. 12/27

6:45 pm-9:35 am

2 stops14h 50m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 15 results
1
2

Compare providers for flights from Memphis to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Memphis to Des Moines in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Memphis-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Memphis-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Memphis-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Memphis-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Memphis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Memphis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Memphis to Des Moines

What is the cheapest time of day to fly from MEM to DSM?

Find hourly flight availability from Memphis to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated noviembre 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Memphis to Des Moines in the evening. If you’re flexible enough to do this you can expect to save up to 51% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated noviembre 6, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,001 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,040 reviews
Delta
7.9
Good
8,001 reviews

Food

7.3

Comfort

7.9

Crew

8.5

Entertainment

7.9

Overall

7.9

Boarding

8.2

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Memphis to Des Moines?

    Airlines like American Airlines, United Airlines, and Southwest fly from Memphis to Des Moines in about 5h 35m. The time it takes to get you to your destination can typically vary by up to 5h 30m. There are 491 mi between Memphis and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Memphis to Des Moines round-trip?

    Currently priced at $201, Delta will fly you from Memphis to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $241. These flights start at 50% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Memphis to Des Moines one-way?

    To fly one-way, consider booking your trip with Frontier, which is currently one of the cheapest options available, starting at $65. Allegiant Air flights start at $120 while deals on American Airlines start at $169 one-way.

  • Can I find deals for flights from Memphis to Des Moines that include hotel bookings?

    Yes. In addition to deals on Memphis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Memphis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Memphis to Des Moines.

  • Can I find deals for business class flights from Memphis to Des Moines?

    Yes. Cheapflights offers flight deals from Memphis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from Memphis to Des Moines

Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$201Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$241Average$357FlexibilityNo cancel feeOn-time71%

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