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Des Moines

$134+ Cheap flights from Memphis to Des Moines (MEM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Memphis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$220
(Kiwi.com)

One-way from

$134
(United Airlines)

Popular in

March

Cheapest in

May

Average price

$402
From Memphis to Des Moines
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One-way flight from Memphis to Des Moines
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Highest demand for flights based on searches. 12% potential increase in price ($49 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Memphis to Des Moines

Cheapest flights from Memphis to Des Moines
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/98:10 pmMEM - DSM
1 stop17h 42mFrontier
Thu 10/162:37 pmDSM - MEM
1 stop28h 50mFrontier
Deal found 9/11$220
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/110:57 amMEM - DSM
1 stop6h 27mUnited Airlines
Mon 10/63:25 pmDSM - MEM
1 stop6h 23mUnited Airlines
Deal found 9/10$228
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:19 amMEM - DSM
1 stop7h 18mAmerican Airlines
Wed 10/226:07 pmDSM - MEM
1 stop5h 52mAmerican Airlines
Deal found 9/11$240
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:27 pmMEM - DSM
1 stop6h 35mAmerican Airlines
Mon 10/206:22 pmDSM - MEM
1 stop5h 37mAmerican Airlines
Deal found 9/8$271
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amMEM - DSM
1 stop4h 26mDelta
Sun 11/25:32 pmDSM - MEM
1 stop4h 24mDelta
Deal found 9/10$273
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/138:10 pmMEM - DSM
1 stop17h 39mMultiple Airlines
Sun 11/169:03 pmDSM - MEM
2 stops18h 11mMultiple Airlines
Deal found 9/9$275
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/95:00 amMEM - DSM
1 stop5h 51mAmerican Airlines
Thu 10/166:07 pmDSM - MEM
1 stop5h 52mAmerican Airlines
Deal found 9/9$279
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/103:35 pmMEM - DSM
1 stop4h 36mAmerican Airlines
Sat 10/116:22 pmDSM - MEM
1 stop5h 37mAmerican Airlines
Deal found 9/10$284
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:29 amMEM - DSM
1 stop5h 34mAmerican Airlines
Sun 10/196:05 amDSM - MEM
1 stop7h 19mAmerican Airlines
Deal found 9/9$295
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/108:56 amMEM - DSM
1 stop7h 21mUnited Airlines
Sun 10/1211:31 amDSM - MEM
1 stop6h 11mUnited Airlines
Deal found 9/10$297

Cheapflights Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Memphis

Fly to

Des Moines

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 10/1

10:57 am-5:24 pm

1 stop6h 27m

Des Moines

Mon 10/6

3:25 pm-9:48 pm

1 stop6h 23m

$228

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Mon 10/20

10:19 am-5:37 pm

1 stop7h 18m

Des Moines

Wed 10/22

6:07 pm-11:59 pm

1 stop5h 52m

$240

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 10/8

5:27 pm-12:02 am

1 stop6h 35m

Des Moines

Mon 10/20

6:22 pm-11:59 pm

1 stop5h 37m

$271

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/31

7:00 am-1:46 pm

1 stop6h 46m

Des Moines

Sun 11/2

6:40 pm-12:02 am

1 stop5h 22m

$273

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Thu 11/13

8:10 pm-1:49 pm

1 stop17h 39m

Des Moines

Sun 11/16

9:03 pm-3:14 pm

2 stops18h 11m

$275

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Thu 10/9

5:00 am-10:51 am

1 stop5h 51m

Des Moines

Thu 10/16

6:07 pm-11:59 pm

1 stop5h 52m

$279

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/10

3:35 pm-8:11 pm

1 stop4h 36m

Des Moines

Sat 10/11

6:22 pm-11:59 pm

1 stop5h 37m

$284

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/31

6:00 am-10:26 am

1 stop4h 26m

Des Moines

Sun 11/2

2:40 pm-9:56 pm

1 stop7h 16m

$287

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/17

9:29 am-3:03 pm

1 stop5h 34m

Des Moines

Sun 10/19

6:05 am-1:24 pm

1 stop7h 19m

$295

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Fri 10/10

10:57 am-5:24 pm

1 stop6h 27m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 12 results
1
2

Best time to book a flight from Memphis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Memphis to Des Moines

What is the cheapest time of day to fly from MEM to DSM?

Find hourly flight availability from Memphis to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Memphis to Des Moines in the morning. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Memphis to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Memphis to Des Moines?

    Airlines like United Airlines and American Airlines fly from Memphis to Des Moines in about 6h 27m. The time it takes to get you to your destination can typically vary by up to 51m. There are 491 mi between Memphis and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Memphis to Des Moines round-trip?

    Currently priced at $231, Delta will fly you from Memphis to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $241. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Memphis to Des Moines that include hotel bookings?

    Yes. In addition to deals on Memphis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Memphis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Memphis to Des Moines.

  • Can I find deals for business class flights from Memphis to Des Moines?

    Yes. Cheapflights offers flight deals from Memphis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Memphis to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Memphis to Des Moines (average of $336). Flying from Memphis to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 2 airlines flying from Memphis to Des Moines

Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$231Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$241Average$313FlexibilityNo cancel feeOn-time71%

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