HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$137+ Cheap flights from Memphis to Des Moines (MEM - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
MEM — DSM
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Memphis to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Memphis to Des Moines

Cheapest flights from Memphis to Des Moines
Explore the most affordable flight options available from Memphis to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:00 am
MEM
-
DSM
1 stop5h 01m
Delta
Sat 2/2812:28 pm
DSM
-
MEM
1 stop5h 27m
Delta
Deal found 2/2$299
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:00 pm
MEM
-
DSM
1 stop5h 42m
Delta
Tue 8/185:45 am
DSM
-
MEM
1 stop6h 52m
Delta
Deal found 2/2$307
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/216:00 am
MEM
-
DSM
1 stop4h 15m
Delta
Sun 8/165:45 am
DSM
-
MEM
1 stop6h 52m
Delta
Deal found 2/2$317
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:55 pm
MEM
-
DSM
1 stop4h 31m
Delta
Tue 8/185:35 pm
DSM
-
MEM
1 stop4h 49m
Delta
Deal found 2/2$318
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
MEM
-
DSM
1 stop7h 18m
American Airlines
Wed 3/117:44 pm
DSM
-
MEM
1 stop4h 15m
American Airlines
Deal found 2/4$319
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/195:30 am
MEM
-
DSM
1 stop4h 44m
Delta
Sun 8/165:45 am
DSM
-
MEM
1 stop6h 52m
Delta
Deal found 2/2$327
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/205:55 pm
MEM
-
DSM
1 stop4h 31m
Delta
Sun 8/165:45 am
DSM
-
MEM
1 stop6h 52m
Delta
Deal found 2/2$328
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:25 pm
MEM
-
DSM
2 stops9h 15m
Southwest
Tue 8/186:10 am
DSM
-
MEM
1 stop5h 35m
Southwest
Deal found 2/2$332
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/135:38 am
MEM
-
DSM
1 stop4h 56m
American Airlines
Fri 3/206:40 am
DSM
-
MEM
1 stop4h 30m
American Airlines
Deal found 2/3$337
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
MEM
-
DSM
1 stop4h 15m
Delta
Wed 8/195:35 pm
DSM
-
MEM
1 stop4h 49m
Delta
Deal found 2/2$353
This Delta deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:00 am
MEM
-
DSM
1 stop4h 15m
Delta
Tue 8/185:45 am
DSM
-
MEM
1 stop6h 52m
Delta
Deal found 2/2$354

Find flight deals from Memphis to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Memphis (MEM) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$299
(Delta)

One-way from

$137
(Kiwi.com)

Popular in

March

Cheapest in

September

Average price

$379
Provider with most accurate pricing for Memphis-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Memphis-Des Moines flights.
Search Deals
From Memphis to Des Moines
Search Deals
One-way flight from Memphis to Des Moines
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($24 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Memphis to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Memphis to Des Moines that are best for you.

Fly from

Memphis

Fly to

Des Moines

Route

Depart

Return

Price

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Sat 2/28

5:38 am-10:44 am

1 stop5h 06m

Des Moines

Sun 3/1

5:00 am-11:05 am

1 stop6h 05m

$299

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 7/21

5:55 pm-10:26 pm

1 stop4h 31m

Des Moines

Wed 8/19

2:15 pm-8:28 pm

1 stop6h 13m

$307

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 7/22

6:00 am-10:15 am

1 stop4h 15m

Des Moines

Tue 8/18

5:45 am-10:48 am

1 stop5h 03m

$307

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 7/22

5:30 am-10:14 am

1 stop4h 44m

Des Moines

Wed 8/19

10:15 am-4:53 pm

1 stop6h 38m

$307

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 7/21

12:00 pm-5:42 pm

1 stop5h 42m

Des Moines

Tue 8/18

5:45 am-12:37 pm

1 stop6h 52m

$307

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 6/10

7:15 am-12:30 pm

1 stop5h 15m

Des Moines

Sat 6/13

6:00 am-11:00 am

1 stop5h 00m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 7/22

5:30 am-10:14 am

1 stop4h 44m

Des Moines

Mon 8/17

6:30 pm-10:48 pm

1 stop4h 18m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Tue 7/21

12:00 pm-5:42 pm

1 stop5h 42m

Des Moines

Thu 8/20

7:00 am-11:16 am

1 stop4h 16m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 7/22

5:30 am-10:14 am

1 stop4h 44m

Des Moines

Sun 8/16

5:45 am-12:37 pm

1 stop6h 52m

$317

MemphisDes Moines

MEM - DSM

MEMDSM

Memphis

Wed 7/22

5:30 am-10:14 am

1 stop4h 44m

Des Moines

Thu 8/20

5:45 am-12:37 pm

1 stop6h 52m

$317

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/4

Showing 1-10 of 18 results
1
2

Compare providers for flights from Memphis to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Memphis to Des Moines in February.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Memphis-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Memphis-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Memphis-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Memphis-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Memphis-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Memphis to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Memphis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated February 5, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from Memphis to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,151 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,151 reviews
Delta
7.9
Good
8,151 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,237 reviews
Delta
7.9
Good
8,151 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Memphis to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Memphis to Des Moines?

    Airlines like American Airlines and Delta fly from Memphis to Des Moines in about 4h 31m. The time it takes to get you to your destination can typically vary by up to 35m. There are 491 mi between Memphis and Des Moines. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Memphis to Des Moines round-trip?

    Currently priced at $201, Delta will fly you from Memphis to Des Moines and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on American Airlines for as low as $241. These flights start at 45% lower than the current average price 3 months from now.

  • Can I find deals for flights from Memphis to Des Moines that include hotel bookings?

    Yes. In addition to deals on Memphis to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Memphis to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Memphis to Des Moines.

  • Can I find deals for business class flights from Memphis to Des Moines?

    Yes. Cheapflights offers flight deals from Memphis to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 2 airlines flying from Memphis to Des Moines

Discover the top 2 airlines that operate flights from Memphis to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$201Average$452FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$241Average$326FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.