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Des Moines

$48+ Cheap flights from Massachusetts to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/5. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — DSM
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Massachusetts to Des Moines

Cheapest flights from Massachusetts to Des Moines
Explore the most affordable flight options available from Massachusetts to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:50 pmBOS - DSM
Nonstop3h 13mMultiple Airlines
Tue 1/610:53 amDSM - BOS
1 stop23h 41mMultiple Airlines
Deal found 12/16$315
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:50 pmBOS - DSM
Nonstop3h 13mMultiple Airlines
Wed 1/76:14 pmDSM - BOS
2 stops36h 39mMultiple Airlines
Deal found 12/16$319
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amBOS - DSM
1 stop6h 26mAmerican Airlines
Mon 1/51:25 pmDSM - BOS
1 stop9h 26mAmerican Airlines
Deal found 12/16$331
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:56 amBOS - DSM
3 stops52h 04mMultiple Airlines
Mon 1/58:00 amDSM - BOS
Nonstop2h 55mMultiple Airlines
Deal found 12/16$362
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:25 amBOS - DSM
2 stops8h 40mUnited Airlines
Wed 12/313:14 pmDSM - BOS
2 stops7h 40mUnited Airlines
Deal found 12/17$367
This Kiwi.com deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:22 amALB - DSM
1 stop11h 51mMultiple Airlines
Mon 1/56:35 amDSM - ALB
2 stops27h 58mMultiple Airlines
Deal found 12/14$369
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:50 pmBOS - DSM
Nonstop3h 13mMultiple Airlines
Thu 1/84:30 pmDSM - BOS
2 stops30h 27mMultiple Airlines
Deal found 12/16$369
This Booking.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:50 pmBOS - DSM
Nonstop3h 13mAllegiant Air
Mon 12/228:05 amDSM - BOS
Nonstop2h 55mAllegiant Air
Deal found 12/17$387
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:30 amBDL - DSM
1 stop5h 19mDelta
Tue 1/65:16 pmDSM - BDL
1 stop5h 39mDelta
Deal found 12/16$475
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:00 amALB - DSM
1 stop5h 50mUnited Airlines
Tue 1/63:35 pmDSM - ALB
1 stop4h 48mUnited Airlines
Deal found 12/16$475
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:15 pmALB - DSM
2 stops11h 55mSouthwest
Tue 1/66:10 amDSM - ALB
2 stops9h 05mSouthwest
Deal found 12/16$485
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/226:00 amALB - DSM
1 stop5h 50mUnited Airlines
Mon 1/53:14 pmDSM - ALB
1 stop4h 51mUnited Airlines
Deal found 12/14$522

Find flight deals from Massachusetts to Des Moines

Keep the following information in mind while searching for Massachusetts to Des Moines flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$141
(Gotogate)

One-way from

$48
(Booking.com)

Popular in

March

Cheapest in

December

Average price

$203

Good round-trip deal

$125 or less

Good one-way deal

$55 or less
Provider with most accurate pricing for Boston Logan Intl-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Boston Logan Intl-Des Moines flights.
Search Deals
From Massachusetts to Des Moines
Search Deals
One-way flight from Massachusetts to Des Moines
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($67 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Massachusetts to Des Moines.
Search Deals
Price to beat on a one-way flight from Massachusetts to Des Moines.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Massachusetts to Des Moines that are best for you.

Fly from

Massachusetts

Fly to

Des Moines

Route

Depart

Return

Price

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Mon 1/5

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Fri 1/9

11:09 am-2:38 pm

2 stops26h 29m

$220

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Sat 1/17

7:15 am-12:46 pm

1 stop6h 31m

Des Moines

Tue 1/20

7:40 am-3:56 pm

1 stop7h 16m

$237

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Fri 1/2

12:45 pm-2:58 pm

Nonstop3h 13m

Des Moines

Mon 1/5

8:29 pm-10:01 am

2 stops36h 32m

$240

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Thu 1/15

7:00 am-4:24 pm

1 stop10h 24m

Des Moines

Sun 1/18

6:00 am-12:53 pm

1 stop5h 53m

$276

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Tue 1/20

2:20 pm-9:50 pm

2 stops8h 30m

Des Moines

Wed 1/21

5:30 am-2:02 pm

1 stop7h 32m

$286

HartfordDes Moines

BDL - DSM

BDLDSM

Hartford Bradley Intl

Wed 1/14

9:55 am-2:33 pm

1 stop5h 38m

Des Moines

Sat 1/17

7:50 am-2:22 pm

1 stop5h 32m

$309

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Mon 2/9

7:00 am-4:24 pm

1 stop10h 24m

Des Moines

Tue 2/10

7:00 am-5:03 pm

1 stop9h 03m

$315

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Fri 1/9

6:43 am-4:24 pm

1 stop10h 41m

Des Moines

Mon 1/12

11:42 am-10:31 pm

1 stop9h 49m

$315

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Tue 1/6

12:55 pm-9:04 pm

1 stop9h 09m

Des Moines

Fri 1/9

11:42 am-10:31 pm

1 stop9h 49m

$315

BostonDes Moines

BOS - DSM

BOSDSM

Boston Logan Intl

Sat 1/17

3:15 pm-11:44 pm

1 stop9h 29m

Des Moines

Tue 1/20

8:00 am-6:57 pm

2 stops9h 57m

$322

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 41 results
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Best time to book a flight from Massachusetts to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Des Moines

What is the cheapest month to book a flight from Massachusetts to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Massachusetts to Des Moines (average of $92). Flying from Massachusetts to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to DSM?

Find hourly flight availability from Massachusetts to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Massachusetts to Des Moines in the morning. By choosing this option you can save up to 67% on the cost of your flight, compared to a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Massachusetts?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Massachusetts to Des Moines.

  • How long is the flight from Massachusetts to Des Moines?

    Airlines like American Airlines, United Airlines, and Delta fly from Massachusetts to Des Moines in about 5h 16m. The time it takes to get you to your destination can typically vary by up to 1h 15m. Airlines will cover a distance of 1078 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Massachusetts to Des Moines one-way?

    One-way options have recently been found by users for as low as $46 on Allegiant Air. Other airlines that offer cheap prices include American Airlines from $130 and Delta from $142 one-way.

  • What are the most popular routes from Massachusetts to Des Moines?

    Most travelers choose Boston Logan Intl - Des Moines, Hartford Bradley Intl - Des Moines or Albany Intl - Des Moines when deciding on the best route from Massachusetts to Des Moines.

  • What are the cheapest flights from Massachusetts to Des Moines?

    Looking at all options, your cheapest flight can be booked for $48. While the most popular route (Boston Logan Intl - Des Moines) can be booked for $141 on average, our data indicates $236 when flying from Massachusetts to Des Moines.

  • Can I find deals for flights from Massachusetts to Des Moines that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Des Moines.

  • Can I find deals for business class flights from Massachusetts to Des Moines?

    Yes. Cheapflights offers flight deals from Massachusetts to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Massachusetts to Des Moines (average of $92). Flying from Massachusetts to Des Moines in February is currently the most expensive (average of $339). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Massachusetts to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Massachusetts to Des Moines

Discover the top 5 airlines that operate flights from Massachusetts to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Allegiant AirCheapest$93Average$159FlexibilityNo cancel feeOn-time88%
DeltaCheapest$260Average$395FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$289Average$416FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$296Average$421FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$333Average$417FlexibilityNo cancel feeOn-time63%

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