HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$185+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/4. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Lexington to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$249
(United Airlines)

One-way from

$185
(Kiwi.com)

Popular in

April

Cheapest in

September

Average price

$263
From Lexington Blue Grass to Des Moines
Search Deals
One-way flight from Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($88 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:05 amLEX - DSM
1 stop6h 14mUnited Airlines
Wed 10/88:00 amDSM - LEX
1 stop6h 48mUnited Airlines
Deal found 9/10$249
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/112:39 pmLEX - DSM
2 stops8h 42mAmerican Airlines
Wed 10/81:48 pmDSM - LEX
1 stop3h 42mAmerican Airlines
Deal found 9/10$254
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/125:48 pmLEX - DSM
1 stop4h 57mUnited Airlines
Mon 9/1511:35 amDSM - LEX
1 stop4h 32mUnited Airlines
Deal found 9/10$339
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:33 pmLEX - DSM
1 stop22h 51mUnited Airlines
Tue 9/306:36 pmDSM - LEX
1 stop4h 23mUnited Airlines
Deal found 9/11$418
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/129:50 amLEX - DSM
2 stops9h 39mAmerican Airlines
Mon 9/154:09 pmDSM - LEX
1 stop7h 17mAmerican Airlines
Deal found 9/10$427
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2612:54 pmLEX - DSM
1 stop4h 55mAmerican Airlines
Tue 9/305:10 amDSM - LEX
2 stops8h 56mAmerican Airlines
Deal found 9/11$462
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/224:06 pmLEX - DSM
2 stops8h 00mAmerican Airlines
Tue 9/235:10 amDSM - LEX
1 stop5h 50mAmerican Airlines
Deal found 9/11$692
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:05 amLEX - DSM
1 stop6h 09mUnited Airlines
Tue 10/286:50 pmDSM - LEX
1 stop3h 54mUnited Airlines
Deal found 9/11$796
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:55 amLEX - DSM
2 stops10h 18mDelta
Wed 10/82:40 pmDSM - LEX
2 stops5h 47mDelta
Deal found 9/10$1,684

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Lexington

Fly to

Des Moines

Route

Depart

Return

Price

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 10/1

7:05 am-12:19 pm

1 stop6h 14m

Des Moines

Wed 10/8

8:00 am-3:48 pm

1 stop6h 48m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/18

5:50 pm-8:53 pm

1 stop4h 03m

Des Moines

Sat 2/21

10:15 am-5:13 pm

1 stop5h 58m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 10/1

12:39 pm-8:21 pm

2 stops8h 42m

Des Moines

Wed 10/8

1:48 pm-6:30 pm

1 stop3h 42m

$254

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/19

11:00 am-4:56 pm

1 stop6h 56m

Des Moines

Mon 2/23

10:15 am-5:13 pm

1 stop5h 58m

$314

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/18

8:49 am-2:26 pm

2 stops6h 37m

Des Moines

Sat 2/21

4:27 pm-11:55 pm

2 stops6h 28m

$373

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/19

8:49 am-2:26 pm

2 stops6h 37m

Des Moines

Mon 2/23

12:47 pm-11:55 pm

2 stops10h 08m

$374

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 9/26

7:33 pm-5:24 pm

1 stop22h 51m

Des Moines

Tue 9/30

6:36 pm-11:59 pm

1 stop4h 23m

$418

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 9/26

12:54 pm-4:49 pm

1 stop4h 55m

Des Moines

Tue 9/30

5:10 am-3:06 pm

2 stops8h 56m

$462

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 9/22

4:06 pm-11:06 pm

2 stops8h 00m

Des Moines

Tue 9/23

5:10 am-12:00 pm

1 stop5h 50m

$692

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sun 10/26

7:05 am-12:14 pm

1 stop6h 09m

Des Moines

Tue 10/28

6:50 pm-11:44 pm

1 stop3h 54m

$796

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 14 results
1
2

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Des Moines

What is the cheapest month to book a flight from Lexington to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $336). Flying from Lexington to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to DSM?

Find hourly flight availability from Lexington to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

When flying from Lexington to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 10% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Crew

8.5

Food

7.3

Overall

8.0

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like United Airlines, Delta, and American Airlines fly from Lexington to Des Moines in about 4h 03m. The time it takes to get you to your destination can typically vary by up to 4h 39m. Airlines will cover a distance of 537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $208. Other airlines that can offer you cheap pricing are American Airlines, from $248, and United Airlines, from $272. Delta is 51% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $336). Flying from Lexington to Des Moines in June is currently the most expensive (average of $402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Lexington to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Cincinnati to Omaha flights
Nashville to Omaha flights
Cincinnati to Des Moines flights
Lexington to Cedar Rapids flights
Nashville to Des Moines flights
Lexington to Omaha flights
Cincinnati to Moline flights
Cincinnati to Cedar Rapids flights
Nashville to Cedar Rapids flights
Knoxville to Omaha flights
Nashville to Moline flights
Knoxville to Des Moines flights
Louisville to Omaha flights
Louisville to Des Moines flights
Louisville to Moline flights
Nashville to La Crosse flights
Nashville to Sioux City flights
Louisville to Cedar Rapids flights
Cincinnati to La Crosse flights
Lexington to Moline flights
Nashville to Waterloo flights
Knoxville to Moline flights
Knoxville to La Crosse flights
Paducah to Omaha flights
Nashville to Dubuque flights
Louisville to Waterloo flights
Blountville to Waterloo flights
Lexington to Sioux City flights
Lexington to Waterloo flights

Top 3 airlines flying from Lexington to Des Moines

Discover the top 3 airlines that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$283FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$347FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$272Average$318FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.