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Des Moines

$249+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Apr 12 — Apr 191
Sun 4/12
Sun 4/19
1 adult, Economy
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Cheap flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.

This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:00 am
LEX
-
DSM
1 stop4h 26m
American Airlines
Sun 5/1011:09 am
DSM
-
LEX
1 stop5h 11m
American Airlines
Deal found 3/9$289
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1410:15 am
LEX
-
DSM
1 stop5h 10m
United Airlines
Sat 4/1811:25 am
DSM
-
LEX
1 stop4h 37m
United Airlines
Deal found 3/11$309
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
LEX
-
DSM
2 stops8h 46m
American Airlines
Sat 4/185:01 pm
DSM
-
LEX
1 stop5h 37m
American Airlines
Deal found 3/11$314
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:01 pm
LEX
-
DSM
1 stop4h 31m
United Airlines
Wed 4/153:21 pm
DSM
-
LEX
1 stop4h 03m
United Airlines
Deal found 3/11$379
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:25 am
LEX
-
DSM
1 stop3h 58m
United Airlines
Sat 3/288:00 am
DSM
-
LEX
1 stop4h 15m
United Airlines
Deal found 3/9$389
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:01 pm
LEX
-
DSM
1 stop4h 31m
United Airlines
Mon 4/133:21 pm
DSM
-
LEX
1 stop6h 08m
United Airlines
Deal found 3/10$409

Find flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$289
(American Airlines)

One-way from

$249
(United Airlines)

Popular in

April

Cheapest in

January

Average price

$422
Provider with most accurate pricing for Lexington Blue Grass-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Des Moines flights.
Search Deals
From Lexington Blue Grass to Des Moines
Search Deals
One-way flight from Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 5/5

6:00 am-1:46 pm

2 stops8h 46m

Des Moines

Sun 5/10

6:00 am-2:29 pm

2 stops7h 29m

$300

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 5/20

7:50 pm-11:24 pm

1 stop4h 34m

Des Moines

Sat 5/23

6:00 am-1:20 pm

1 stop6h 20m

$309

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 4/30

7:00 am-10:26 am

1 stop4h 26m

Des Moines

Wed 5/6

5:44 am-2:57 pm

2 stops8h 13m

$314

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 4/14

6:00 am-1:46 pm

2 stops8h 46m

Des Moines

Sat 4/18

5:01 pm-11:38 pm

1 stop5h 37m

$314
Quickest round-trip

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 3/24

10:25 am-1:23 pm

1 stop3h 58m

Des Moines

Sat 3/28

8:00 am-1:15 pm

1 stop4h 15m

$389

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sat 4/11

5:30 am-10:44 am

1 stop6h 14m

Des Moines

Wed 4/15

3:21 pm-8:24 pm

1 stop4h 03m

$409

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 4/6

6:01 pm-9:32 pm

1 stop4h 31m

Des Moines

Mon 4/13

3:21 pm-10:29 pm

1 stop6h 08m

$409

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 6/19

7:00 am-10:27 am

1 stop4h 27m

Des Moines

Sun 6/21

6:00 am-1:20 pm

1 stop6h 20m

$469
Cheapest one-way
Quickest one-way

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 4/14

7:00 am-10:44 am

1 stop4h 44m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Tue 4/14

6:00 am-1:46 pm

2 stops8h 46m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Lexington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Des Moines

What is the cheapest month to book a flight from Lexington to Des Moines?

Currently, September is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $236). Flying from Lexington to Des Moines in February is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 13, 2026.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as Delta,United Airlines, andAmerican Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,291 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,423 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,464 reviews
Delta
7.9
Good
8,291 reviews

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like American Airlines and United Airlines fly from Lexington to Des Moines in about 4h 34m. The time it takes to get you to your destination can typically vary by up to 4h 12m. Airlines will cover a distance of 537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $248. American Airlines is 41% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $236). Flying from Lexington to Des Moines in February is currently the most expensive (average of $524). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Lexington to Des Moines

Discover the top 3 airlines that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$289FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$283FlexibilityNo cancel feeOn-timeN/A

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