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Des Moines

$249+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(Delta)

Popular in

April

Cheapest in

September

Average price

$318
Provider with most accurate pricing for Lexington Blue Grass-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Lexington Blue Grass-Des Moines flights.
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From Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($82 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($39 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:33 amLEX - DSM
1 stop6h 43mDelta
Sat 12/611:23 amDSM - LEX
1 stop4h 15mDelta
Deal found 10/28$249
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:58 pmLEX - DSM
1 stop5h 50mAmerican Airlines
Sat 12/68:50 amDSM - LEX
2 stops9h 54mAmerican Airlines
Deal found 10/28$254
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/55:15 pmLEX - DSM
1 stop6h 19mDelta
Sun 12/76:33 pmDSM - LEX
1 stop4h 35mDelta
Deal found 10/27$284
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:48 pmLEX - DSM
1 stop3h 47mDelta
Sun 11/95:52 pmDSM - LEX
1 stop3h 55mDelta
Deal found 10/27$319
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:11 pmLEX - DSM
1 stop7h 35mAmerican Airlines
Sun 11/25:00 amDSM - LEX
1 stop7h 29mAmerican Airlines
Deal found 10/27$334
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:00 amLEX - DSM
1 stop4h 29mUnited Airlines
Sun 12/75:15 pmDSM - LEX
2 stops19h 07mUnited Airlines
Deal found 10/27$427
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:03 amLEX - DSM
2 stops10h 29mAmerican Airlines
Sun 11/94:02 pmDSM - LEX
2 stops6h 57mAmerican Airlines
Deal found 10/27$650

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Lexington

Fly to

Des Moines

Route

Depart

Return

Price

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 12/5

5:15 pm-10:34 pm

1 stop6h 19m

Des Moines

Sun 12/7

5:43 pm-10:50 pm

1 stop4h 07m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 12/3

10:33 am-4:16 pm

1 stop6h 43m

Des Moines

Sat 12/6

11:23 am-4:38 pm

1 stop4h 15m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 12/3

6:58 pm-11:48 pm

1 stop5h 50m

Des Moines

Sat 12/6

8:50 am-7:44 pm

2 stops9h 54m

$254

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 2/13

5:55 am-10:23 am

1 stop5h 28m

Des Moines

Mon 2/16

10:15 am-5:13 pm

1 stop5h 58m

$274

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 11/13

6:00 am-10:42 am

1 stop5h 42m

Des Moines

Mon 11/17

6:32 pm-12:04 am

1 stop4h 32m

$279

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 11/13

5:00 am-1:16 pm

2 stops9h 16m

Des Moines

Mon 11/17

2:19 pm-11:16 pm

2 stops7h 57m

$289

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/18

6:00 am-1:06 pm

1 stop8h 06m

Des Moines

Sat 2/21

3:25 pm-9:58 pm

1 stop5h 33m

$319

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/18

11:00 am-4:56 pm

1 stop6h 56m

Des Moines

Sat 2/21

7:00 am-9:39 pm

2 stops13h 39m

$373

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 12/22

8:04 am-12:48 pm

1 stop5h 44m

$274

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sun 12/21

5:48 pm-9:40 pm

1 stop4h 52m

$274

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 11 results
1
2

Compare providers for flights from Lexington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in October.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Des Moines

What is the cheapest month to book a flight from Lexington to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $157). Flying from Lexington to Des Moines in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to DSM?

Find hourly flight availability from Lexington to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

When flying from Lexington to Des Moines, the time of day you fly usually plays a role in the price. Save by searching for a flight in the morning, which can drop the price by up to 46% versus a flight at noon.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as Delta, United Airlines, and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like Delta and American Airlines fly from Lexington to Des Moines in about 5h 50m. The time it takes to get you to your destination can typically vary by up to 29m. Airlines will cover a distance of 537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $248. Other airlines that can offer you cheap pricing are Delta, from $248, and United Airlines, from $272. American Airlines is 42% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $157). Flying from Lexington to Des Moines in December is currently the most expensive (average of $388). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top 3 airlines flying from Lexington to Des Moines

Discover the top 3 airlines that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$283FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$272Average$318FlexibilityNo cancel feeOn-time69%

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