HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Des Moines

$249+ Cheap flights from Lexington to Des Moines (LEX - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — DSM
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Lexington to Des Moines with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Lexington to Des Moines

Cheapest flights from Lexington to Des Moines
Explore the most affordable flight options available from Lexington to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/114:35 pm
LEX
-
DSM
1 stop7h 33m
American Airlines
Sun 2/155:00 am
DSM
-
LEX
1 stop3h 28m
American Airlines
Deal found 1/26$279
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:13 am
LEX
-
DSM
1 stop4h 48m
Delta
Sat 2/285:24 am
DSM
-
LEX
1 stop7h 01m
Delta
Deal found 1/27$314
This United Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/145:45 pm
LEX
-
DSM
1 stop4h 56m
United Airlines
Wed 2/186:55 pm
DSM
-
LEX
1 stop3h 54m
United Airlines
Deal found 1/25$344
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/265:07 pm
LEX
-
DSM
1 stop7h 33m
American Airlines
Fri 2/277:44 pm
DSM
-
LEX
1 stop12h 44m
American Airlines
Deal found 1/27$357
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/98:00 am
LEX
-
DSM
1 stop4h 28m
American Airlines
Sun 4/128:01 pm
DSM
-
LEX
1 stop13h 30m
American Airlines
Deal found 1/28$377
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:07 pm
LEX
-
DSM
1 stop7h 33m
American Airlines
Mon 2/165:00 am
DSM
-
LEX
1 stop3h 28m
American Airlines
Deal found 1/26$407
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/128:30 am
LEX
-
DSM
1 stop5h 47m
American Airlines
Mon 2/165:00 am
DSM
-
LEX
2 stops6h 49m
American Airlines
Deal found 1/28$417
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/267:13 am
LEX
-
DSM
1 stop4h 48m
Delta
Fri 2/2710:57 am
DSM
-
LEX
2 stops22h 02m
Delta
Deal found 1/27$433
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:21 am
LEX
-
DSM
2 stops13h 19m
American Airlines
Sat 2/285:00 am
DSM
-
LEX
1 stop3h 28m
American Airlines
Deal found 1/27$452

Find flight deals from Lexington to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Lexington (LEX) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$279
(American Airlines)

One-way from

$249
(Delta)

Popular in

April

Cheapest in

January

Average price

$269
Provider with most accurate pricing for Lexington Blue Grass-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Des Moines flights.
Search Deals
From Lexington Blue Grass to Des Moines
Search Deals
One-way flight from Lexington Blue Grass to Des Moines
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($118 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($47 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Lexington to Des Moines that are best for you.

Fly from

Lexington

Fly to

Des Moines

Route

Depart

Return

Price

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Wed 2/11

4:35 pm-11:08 pm

1 stop7h 33m

Des Moines

Sun 2/15

5:00 am-9:28 am

1 stop3h 28m

$279

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/12

8:30 am-1:17 pm

1 stop5h 47m

Des Moines

Mon 2/16

5:00 am-9:28 am

1 stop3h 28m

$279

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

7:13 am-11:01 am

1 stop4h 48m

Des Moines

Sat 2/28

5:24 am-1:25 pm

1 stop7h 01m

$314

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Sat 2/14

5:45 pm-9:41 pm

1 stop4h 56m

Des Moines

Wed 2/18

6:55 pm-11:49 pm

1 stop3h 54m

$344

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 2/26

5:07 pm-11:40 pm

1 stop7h 33m

Des Moines

Fri 2/27

7:44 pm-9:28 am

1 stop12h 44m

$357

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Thu 4/9

8:00 am-11:28 am

1 stop4h 28m

Des Moines

Sun 4/12

8:01 pm-10:31 am

1 stop13h 30m

$377

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Fri 2/13

5:07 pm-11:40 pm

1 stop7h 33m

Des Moines

Mon 2/16

5:00 am-9:28 am

1 stop3h 28m

$407

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 5/11

5:55 pm-10:29 pm

1 stop5h 34m

$249

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 2/2

9:30 pm-5:24 pm

3 stops44h 54m

$347

LexingtonDes Moines

LEX - DSM

LEXDSM

Lexington Blue Grass

Mon 2/2

8:35 am-2:33 pm

1 stop6h 58m

$364

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 11 results
1
2

Compare providers for flights from Lexington to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Lexington to Des Moines in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Lexington-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lexington-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lexington-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lexington-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lexington-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lexington to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Des Moines

What is the cheapest month to book a flight from Lexington to Des Moines?

Currently, March is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $155). Flying from Lexington to Des Moines in November is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 28, 2026.
Read through reviews of airlines operating flights from Lexington to Des Moines, such as United Airlines and American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,212 reviews

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,212 reviews
United Airlines
7.4
Good
9,212 reviews

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
American Airlines
7.2
Good
11,201 reviews
United Airlines
7.4
Good
9,212 reviews

Food

6.6

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Lexington to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lexington to Des Moines?

    Airlines like American Airlines, Delta, and United Airlines fly from Lexington to Des Moines in about 4h 48m. The time it takes to get you to your destination can typically vary by up to 2h 45m. Airlines will cover a distance of 537 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Lexington to Des Moines round-trip?

    Cheapflights users have booked flights from Lexington to Des Moines round-trip from $248. Another airline that can offer you cheap pricing is United Airlines. American Airlines is 37% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Lexington to Des Moines that include hotel bookings?

    Yes. In addition to deals on Lexington to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Des Moines.

  • Can I find deals for business class flights from Lexington to Des Moines?

    Yes. Cheapflights offers flight deals from Lexington to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Des Moines?

    Currently, March is the cheapest month in which you can book a flight from Lexington to Des Moines (average of $155). Flying from Lexington to Des Moines in November is currently the most expensive (average of $426). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Lexington to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.
Nashville to Omaha flights
Nashville to Cedar Rapids flights
Louisville to Cedar Rapids flights
Nashville to Des Moines flights
Louisville to Des Moines flights
Knoxville to Omaha flights
Cincinnati to Cedar Rapids flights
Knoxville to Des Moines flights
Cincinnati to Moline flights
Louisville to Omaha flights
Lexington to Cedar Rapids flights
Nashville to Moline flights
Cincinnati to Des Moines flights
Cincinnati to Omaha flights
Lexington to Omaha flights
Louisville to Moline flights
Lexington to Moline flights
Nashville to Sioux City flights
Knoxville to Moline flights
Nashville to La Crosse flights
Paducah to Omaha flights
Lexington to Sioux City flights
Cincinnati to La Crosse flights
Nashville to Waterloo flights
Louisville to Waterloo flights
Nashville to Dubuque flights
Lexington to Waterloo flights
Blountville to Waterloo flights
Knoxville to La Crosse flights

Top 2 airlines flying from Lexington to Des Moines

Discover the top 2 airlines that operate flights from Lexington to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$248Average$309FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
Cookie settings©2026 Cheapflights