How long is the flight from Fort Myers to Des Moines?

There are many flights that can get you from Fort Myers to Des Moines in 3h 19m. Fly via Delta, Allegiant Air, or American Airlines to get the fastest option. The distance between Fort Myers and Des Moines is about 1237 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Fort Myers to Des Moines round-trip?

American Airlines, at $236, was found to be the cheapest airline from Fort Myers to Des Moines. An alternate airline flying to your destination would be Southwest. You may be able to fly from Fort Myers to Des Moines for 36% less than the average price by searching for these airlines.

What are the cheapest airlines to fly from Fort Myers to Des Moines one-way?

$43 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $118 and $125, respectively.

In terms of precipitation, rainfall in Des Moines ranges from 1.0 - 4.9 inches per month. June is typically the wettest month, when rainfall can reach 4.9 in. January is typically the driest time to visit Des Moines when rainfall is around 1.0 in.

If weather is an important factor for your trip to Des Moines, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 77.0 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 23.0 F).

What are the cheapest flights from Fort Myers to Des Moines?

While on average a flight from Fort Myers to Des Moines is generally $112, our data shows the cheapest flight currently is $43. When looking at the most popular route, (Fort Myers SW Florida Intl - Des Moines), you can expect to pay $106 for that flight.

Most accurate provider : When it comes to deals on Fort Myers-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Des Moines flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Fort Myers to Des Moines that include hotel bookings?

Yes. In addition to deals on Fort Myers to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Fort Myers to Des Moines?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Des Moines.

Can I find deals for business class flights from Fort Myers to Des Moines?

Yes. Cheapflights offers flight deals from Fort Myers to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$106+ Flights from Fort Myers to Des Moines

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Cheap flight deals from Fort Myers to Des Moines

Cheapest flights from Fort Myers to Des Moines
Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Sun 12/217:00 amRSW - DSM

2 stops16h 26mMultiple Airlines

Mon 12/221:56 pmDSM - RSW

Nonstop3h 04mMultiple Airlines

Deal found 12/10

$379

Fri 12/196:50 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Fri 12/262:00 pmDSM - RSW

Nonstop3h 04mAllegiant Air

Deal found 12/10

$422

Sat 12/277:00 amRSW - DSM

1 stop8h 33mUnited Airlines

Tue 12/306:46 pmDSM - RSW

1 stop22h 43mUnited Airlines

Deal found 12/9

$586

Fri 12/199:23 pmRSW - DSM

2 stops27h 09mMultiple Airlines

Fri 12/262:00 pmDSM - RSW

Nonstop3h 04mMultiple Airlines

Deal found 12/10

$608

Sat 12/276:15 pmRSW - DSM

1 stop6h 40mSouthwest

Tue 12/305:30 amDSM - RSW

2 stops9h 15mSouthwest

Deal found 12/9

$648

Fri 12/2612:27 pmRSW - DSM

1 stop6h 38mUnited Airlines

Tue 12/306:00 amDSM - RSW

1 stop27h 40mUnited Airlines

Deal found 12/11

$682

Tue 12/236:00 amRSW - DSM

1 stop8h 21mAmerican Airlines

Sun 12/286:26 pmDSM - RSW

1 stop4h 57mAmerican Airlines

Deal found 12/11

$789

Sun 12/2112:27 pmRSW - DSM

2 stops12h 31mUnited Airlines

Mon 12/221:30 pmDSM - RSW

2 stops9h 13mUnited Airlines

Deal found 12/10

$807

Best flights from Fort Myers to Des Moines
Discover carefully curated flight deals from Fort Myers to Des Moines that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Fri 1/237:02 pmRSW - DSM

Nonstop3h 19mMultiple Airlines

Mon 1/2611:09 amDSM - RSW

3 stops30h 15mMultiple Airlines

Deal found 12/10

$220

Fri 1/2312:49 pmRSW - DSM

1 stop9h 05mDelta

Mon 1/265:16 pmDSM - RSW

1 stop4h 47mDelta

Deal found 12/10

$261

Mon 2/97:02 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Fri 2/136:00 amDSM - RSW

Nonstop3h 04mAllegiant Air

Deal found 12/10

$294

Thu 1/88:36 amRSW - DSM

1 stop7h 39mAmerican Airlines

Thu 1/154:25 pmDSM - RSW

1 stop6h 08mAmerican Airlines

Deal found 12/10

$337

Mon 2/99:11 pmRSW - DSM

2 stops38h 35mMultiple Airlines

Fri 2/136:00 amDSM - RSW

Nonstop3h 04mMultiple Airlines

Deal found 12/11

$349

Mon 2/93:04 pmRSW - DSM

1 stop8h 07mAmerican Airlines

Fri 2/132:02 pmDSM - RSW

1 stop5h 43mAmerican Airlines

Deal found 12/11

$394

Last-minute flights from Fort Myers to Des Moines
Discover last-minute flight deals from Fort Myers to Des Moines. Data last updated December 12, 2025 and is based on user searches.

Fri 12/196:50 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Fri 12/262:00 pmDSM - RSW

Nonstop3h 04mAllegiant Air

Deal found 12/10

$422

Sun 12/217:00 amRSW - DSM

2 stops16h 26mMultiple Airlines

Mon 12/221:56 pmDSM - RSW

Nonstop3h 04mMultiple Airlines

Deal found 12/10

$379

Thu 1/88:36 amRSW - DSM

1 stop7h 39mAmerican Airlines

Thu 1/154:25 pmDSM - RSW

1 stop6h 08mAmerican Airlines

Deal found 12/10

$337

Thu 1/87:00 amRSW - DSM

1 stop8h 22mUnited Airlines

Mon 1/121:35 pmDSM - RSW

1 stop8h 44mUnited Airlines

Deal found 12/9

$419

Fri 1/237:02 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Mon 1/262:08 pmDSM - RSW

Nonstop3h 04mAllegiant Air

Deal found 12/10

$106

Fri 1/237:02 pmRSW - DSM

Nonstop3h 19mMultiple Airlines

Mon 1/2611:09 amDSM - RSW

3 stops30h 15mMultiple Airlines

Deal found 12/10

$220

Fri 1/2312:49 pmRSW - DSM

1 stop9h 05mDelta

Mon 1/265:16 pmDSM - RSW

1 stop4h 47mDelta

Deal found 12/10

$261

Fri 1/231:12 pmRSW - DSM

2 stops9h 59mAmerican Airlines

Mon 1/261:16 pmDSM - RSW

2 stops9h 17mAmerican Airlines

Deal found 12/10

$271

One-way flights from Fort Myers to Des Moines
Search for one-way flight options from Fort Myers to Des Moines. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Wed 2/189:15 amRSW - DSM

1 stop6h 12mUnited Airlines

Deal found 12/11

$119

Tue 1/274:59 pmRSW - DSM

1 stop6h 30mDelta

Deal found 12/10

$131

Tue 1/278:40 amRSW - DSM

2 stops8h 44mAmerican Airlines

Deal found 12/10

$136

Wed 2/186:00 amRSW - DSM

3 stops37h 47mMultiple Airlines

Deal found 12/11

$143

Wed 1/79:55 pmRSW - DSM

2 stops25h 51mMultiple Airlines

Deal found 12/11

$148

Tue 1/66:04 pmRSW - DSM

1 stop5h 25mDelta

Deal found 12/11

$153

Tue 1/68:40 amRSW - DSM

2 stops8h 44mAmerican Airlines

Deal found 12/11

$158

Thu 12/257:00 amRSW - DSM

1 stop8h 19mUnited Airlines

Deal found 12/10

$159

Mon 1/56:54 pmRSW - DSM

Nonstop3h 19mAllegiant Air

Deal found 12/11

$163

Sat 1/105:35 amRSW - DSM

1 stop7h 40mDelta

Deal found 12/10

$169

Find flight deals from Fort Myers to Des Moines

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$106 (Mytrip)
Popular in	May
Cheapest in	December
Average price	$148

Provider with most accurate pricing for Fort Myers SW Florida Intl-Des Moines flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Des Moines flights.

Search Deals

From Fort Myers SW Florida Intl to Des Moines

Search Deals

Highest demand for flights based on searches. 21% potential increase in price ($102 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($15 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 1/23

7:02 pm-9:21 pm

Nonstop3h 19m

Des Moines

Mon 1/26

11:09 am-6:24 pm

3 stops30h 15m

$220

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Fri 1/23

12:49 pm-8:54 pm

1 stop9h 05m

Des Moines

Mon 1/26

5:16 pm-11:03 pm

1 stop4h 47m

$261

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 2/9

7:02 pm-9:21 pm

Nonstop3h 19m

Des Moines

Fri 2/13

6:00 am-10:04 am

Nonstop3h 04m

$294

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Thu 1/8

8:36 am-3:15 pm

1 stop7h 39m

Des Moines

Thu 1/15

4:25 pm-11:33 pm

1 stop6h 08m

$337

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 2/9

9:11 pm-10:46 am

2 stops38h 35m

Des Moines

Fri 2/13

6:00 am-10:04 am

Nonstop3h 04m

$349

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Mon 2/9

3:04 pm-10:11 pm

1 stop8h 07m

Des Moines

Fri 2/13

2:02 pm-8:45 pm

1 stop5h 43m

$394

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Wed 2/18

1:28 pm-9:51 pm

2 stops9h 23m

$124

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 1/27

4:59 pm-10:29 pm

1 stop6h 30m

$131

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Wed 1/7

9:55 pm-10:46 pm

2 stops25h 51m

$148

Fort MyersDes Moines

RSW - DSM

RSWDSM

Fort Myers SW Florida Intl

Tue 1/6

6:04 pm-10:29 pm

1 stop5h 25m

$153

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 14 results

Compare providers for flights from Fort Myers to Des Moines

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Des Moines in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-Des Moines flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Des Moines flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Des Moines flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Des Moines flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Des Moines

What is the cheapest month to book a flight from Fort Myers to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $64). Flying from Fort Myers to Des Moines in May is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to DSM?

One of the essential ways to save on airfare from Fort Myers to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 67% on airfare.

Reviews of airlines servicing Des Moines

Peruse reviews from past customers who have flown with Southwest and American Airlines from Fort Myers to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,253 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,050 reviews

Southwest

7.9

Good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Fort Myers to Des Moines?
There are many flights that can get you from Fort Myers to Des Moines in 3h 19m. Fly via Delta, Allegiant Air, or American Airlines to get the fastest option. The distance between Fort Myers and Des Moines is about 1237 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Fort Myers to Des Moines round-trip?
American Airlines, at $236, was found to be the cheapest airline from Fort Myers to Des Moines. An alternate airline flying to your destination would be Southwest. You may be able to fly from Fort Myers to Des Moines for 36% less than the average price by searching for these airlines.
What are the cheapest airlines to fly from Fort Myers to Des Moines one-way?
$43 is the cheapest one-way deal found within the past few days, from Allegiant Air. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $118 and $125, respectively.
What are the cheapest flights from Fort Myers to Des Moines?
While on average a flight from Fort Myers to Des Moines is generally $112, our data shows the cheapest flight currently is $43. When looking at the most popular route, (Fort Myers SW Florida Intl - Des Moines), you can expect to pay $106 for that flight.
Can I find deals for flights from Fort Myers to Des Moines that include hotel bookings?
Yes. In addition to deals on Fort Myers to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Des Moines?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Des Moines.
Can I find deals for business class flights from Fort Myers to Des Moines?
Yes. Cheapflights offers flight deals from Fort Myers to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Fort Myers to Des Moines?
Currently, December is the cheapest month in which you can book a flight from Fort Myers to Des Moines (average of $64). Flying from Fort Myers to Des Moines in May is currently the most expensive (average of $434). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Altoona

Johnston

Boone

Ames

Clive

West Des Moines

Ankeny

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Other flights to Des Moines

Top 2 airlines flying from Fort Myers to Des Moines

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$236	Average$343	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$346	Average$388	FlexibilityNo cancel fee	On-time63%

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$106+ Cheap flights from Fort Myers to Des Moines (RSW - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/23. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Des Moines with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Des Moines

Cheapest flights from Fort Myers to Des MoinesExplore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Fort Myers to Des Moines

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Des Moines that are best for you.

Compare providers for flights from Fort Myers to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Des Moines in December.

Best time to book a flight from Fort Myers to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Fort Myers with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Des Moines

What is the cheapest month to book a flight from Fort Myers to Des Moines?

What is the cheapest time of day to fly from RSW to DSM?

Reviews of airlines servicing Des Moines

Peruse reviews from past customers who have flown with Southwest and American Airlines from Fort Myers to Des Moines to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Fort Myers to Des Moines?

What are the cheapest airlines flying from Fort Myers to Des Moines round-trip?

What are the cheapest airlines to fly from Fort Myers to Des Moines one-way?

What are the cheapest flights from Fort Myers to Des Moines?

Can I find deals for flights from Fort Myers to Des Moines that include hotel bookings?

How can I find direct flights from Fort Myers to Des Moines?

Can I find deals for business class flights from Fort Myers to Des Moines?

What is the cheapest month to book a flight from Fort Myers to Des Moines?

Traveling to a place near Des Moines?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Fort Myers to Des Moines

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from Fort Myers to Des Moines

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Cheapest flights from Fort Myers to Des Moines
Explore the most affordable flight options available from Fort Myers to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.