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$457+ Cheap flights from Missouri to the Czech Republic

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Dec 17 — Dec 241
Wed 12/17
Wed 12/24
1 adult, Economy
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Find flight deals from Missouri to Czech Republic

Cheapest flights from Missouri to Czech Republic
Explore the most affordable flight options available from Missouri to Czech Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:24 amMCI - PRG
2 stops18h 41mLufthansa
Wed 1/147:30 amPRG - MCI
2 stops21h 29mLufthansa
Deal found 11/15$500
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmMCI - PRG
2 stops35h 30mUnited Airlines
Mon 1/127:35 amPRG - MCI
2 stops19h 21mUnited Airlines
Deal found 11/16$507
This KAYAK deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:19 pmMCI - PRG
2 stops17h 46mLufthansa
Sun 1/1110:30 amPRG - MCI
2 stops18h 29mLufthansa
Deal found 11/16$512
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:35 pmMCI - PRG
2 stops35h 30mUnited Airlines
Sun 1/113:00 pmPRG - MCI
2 stops50h 32mUnited Airlines
Deal found 11/16$526
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:07 pmMCI - PRG
2 stops22h 18mUnited Airlines
Mon 1/126:15 amPRG - MCI
2 stops21h 18mUnited Airlines
Deal found 11/16$609
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:40 amMCI - PRG
2 stops31h 45mUnited Airlines
Thu 1/151:45 pmPRG - MCI
2 stops15h 14mUnited Airlines
Deal found 11/16$614
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:40 amMCI - PRG
2 stops31h 45mUnited Airlines
Thu 1/151:45 pmPRG - MCI
2 stops15h 14mUnited Airlines
Deal found 11/16$694
This Finnair deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/302:00 pmMCI - PRG
2 stops20h 30mMultiple Airlines
Tue 1/67:35 pmPRG - MCI
2 stops35h 24mMultiple Airlines
Deal found 11/15$715
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/285:07 pmMCI - PRG
2 stops22h 18mUnited Airlines
Sun 1/111:45 pmPRG - MCI
2 stops37h 48mUnited Airlines
Deal found 11/16$719
This Finnair deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:41 amSTL - PRG
2 stops24h 09mMultiple Airlines
Tue 1/67:35 pmPRG - STL
2 stops35h 24mMultiple Airlines
Deal found 11/15$726
This United Airlines deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:07 pmMCI - PRG
2 stops22h 18mUnited Airlines
Sun 1/111:45 pmPRG - MCI
2 stops37h 48mUnited Airlines
Deal found 11/16$804
This Ovago deal was found by Cheapflights users on 11/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/263:50 pmSTL - PRG
1 stop11h 00mLufthansa
Wed 1/73:10 pmPRG - STL
2 stops39h 49mLufthansa
Deal found 11/15$891

Cheap flight deals from Missouri to Czech Republic

Keep the following information in mind while searching for Missouri to Czech Republic flight deals. Data was last updated November 17, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$457
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$754
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Czech Republic
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
Use the filters below to find and compare flights from Missouri to the Czech Republic that are best for you.

Fly from

Missouri

Fly to

Czech Republic

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/9

3:50 pm-9:50 am

1 stop11h 00m

Václav Havel Prague

Fri 1/23

7:35 am-7:27 pm

2 stops18h 52m

$457

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/9

3:50 pm-6:15 pm

1 stop19h 25m

Václav Havel Prague

Mon 1/19

10:25 am-10:58 pm

2 stops19h 33m

$457

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 1/9

6:44 pm-6:25 pm

2 stops16h 41m

Václav Havel Prague

Fri 1/23

6:00 am-9:15 pm

2 stops22h 15m

$498

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

5:45 pm-10:25 pm

2 stops21h 40m

Václav Havel Prague

Tue 1/20

10:30 am-9:59 pm

2 stops18h 29m

$500

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 12/31

11:24 am-1:05 pm

2 stops18h 41m

Václav Havel Prague

Wed 1/14

7:30 am-9:59 pm

2 stops21h 29m

$500

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 1/1

5:07 pm-10:25 pm

2 stops22h 18m

Václav Havel Prague

Tue 1/13

7:25 am-7:56 pm

2 stops19h 31m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 12/31

5:42 pm-5:05 pm

2 stops16h 23m

Václav Havel Prague

Thu 1/15

8:55 am-11:27 pm

2 stops21h 32m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Tue 12/30

6:35 pm-1:05 pm

2 stops35h 30m

Václav Havel Prague

Wed 1/14

7:30 am-9:31 am

2 stops33h 01m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 12/31

5:42 pm-5:05 pm

2 stops16h 23m

Václav Havel Prague

Mon 1/12

6:00 am-6:27 pm

2 stops19h 27m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Tue 12/30

6:35 pm-1:05 pm

2 stops35h 30m

Václav Havel Prague

Fri 1/16

7:35 am-10:40 pm

2 stops22h 05m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 27 results
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Best time to book a flight from Missouri to Czech Republic

Have a flexible travel schedule? Discover the best time to fly to Czech Republic from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to the Czech Republic

What is the cheapest month to book a flight from Missouri to Czech Republic?

Currently, December is the cheapest month in which you can book a flight from Missouri to Czech Republic (average of $343). Flying from Missouri to Czech Republic in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CZ?

Find hourly flight availability from Missouri to Czech Republic. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 17, 2025.

It’s typically best to fly out from Missouri to Czech Republic in the evening. Doing so could potentially save you 22% on the flight price compared to flying in the afternoon, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Czech Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Czech Republic?

    Departing from Missouri to Czech Republic will take you 11h. There are 4783 mi between Missouri and Czech Republic. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Czech Republic one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $499. Lufthansa flights start at $519 while deals on United Airlines start at $719 one-way.

  • Can I find deals for flights from Missouri to Czech Republic that include hotel bookings?

    Yes. In addition to deals on Missouri to Czech Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Czech Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Czech Republic.

  • Can I find deals for business class flights from Missouri to Czech Republic?

    Yes. Cheapflights offers flight deals from Missouri to Czech Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Czech Republic?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Czech Republic (average of $343). Flying from Missouri to Czech Republic in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Czech Republic

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Czech Republic

Discover the top 7 airlines that operate flights from Missouri to Czech Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$509Average$876FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$571Average$968FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$762FlexibilityNo cancel feeOn-time70%
DeltaCheapest$628Average$1,169FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

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