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$355+ Cheap flights from Missouri to the Czech Republic

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Nov 1 — Nov 81
Sat 11/1
Sat 11/8
1 adult, Economy
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Cheap flight deals from Missouri to Czech Republic

Keep the following information in mind while searching for Missouri to Czech Republic flight deals. Data was last updated October 2, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$483
(Kiwi.com)

One-way from

$355
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$777
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
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From Missouri to Czech Republic
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One-way flight from Missouri to Czech Republic
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Highest demand for flights based on searches. 24% potential increase in price ($303 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Missouri to Czech Republic

Cheapest flights from Missouri to Czech Republic
Explore the most affordable flight options available from Missouri to Czech Republic. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 2, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:43 pmSTL - PRG
2 stops14h 22mLufthansa
Sun 11/237:25 amPRG - STL
1 stop13h 30mLufthansa
Deal found 10/1$483
This Gotogate deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/94:05 pmSTL - PRG
2 stops39h 10mAir Canada
Sun 11/239:40 amPRG - STL
2 stops36h 49mAir Canada
Deal found 10/1$543
This FlightHub deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/152:50 pmMCI - PRG
2 stops35h 55mScandinavian Airlines
Sat 11/228:50 pmPRG - MCI
2 stops32h 45mScandinavian Airlines
Deal found 10/2$543
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1210:00 amSTL - PRG
2 stops20h 05mUnited Airlines
Wed 11/267:30 amPRG - STL
1 stop13h 25mUnited Airlines
Deal found 10/2$545
This Cheapflightsfares deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/123:50 pmSTL - PRG
1 stop12h 15mLufthansa
Wed 11/267:30 amPRG - STL
1 stop13h 25mLufthansa
Deal found 10/2$549
This Cheapflightsfares deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:35 pmMCI - PRG
2 stops14h 30mLufthansa
Sat 11/227:35 amPRG - MCI
2 stops21h 15mLufthansa
Deal found 10/2$550
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:30 pmMCI - PRG
2 stops15h 35mUnited Airlines
Sat 11/227:35 amPRG - MCI
2 stops21h 15mUnited Airlines
Deal found 10/2$555
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:19 pmMCI - PRG
2 stops14h 46mUnited Airlines
Wed 1/147:30 amPRG - MCI
2 stops23h 00mUnited Airlines
Deal found 10/2$556
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/63:25 pmMCI - PRG
2 stops24h 00mUnited Airlines
Sat 12/136:15 amPRG - MCI
2 stops21h 32mUnited Airlines
Deal found 10/2$557
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:27 pmSTL - PRG
2 stops21h 58mUnited Airlines
Sun 12/143:00 pmPRG - STL
2 stops31h 40mUnited Airlines
Deal found 10/1$560
This United Airlines deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/156:35 pmMCI - PRG
2 stops14h 30mUnited Airlines
Fri 11/211:45 pmPRG - MCI
2 stops37h 12mUnited Airlines
Deal found 10/2$567
This KAYAK deal was found by Cheapflights users on 10/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/173:25 pmMCI - PRG
2 stops15h 55mScandinavian Airlines
Sat 11/228:50 pmPRG - MCI
2 stops31h 20mScandinavian Airlines
Deal found 10/2$617

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Czech Republic that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
Use the filters below to find and compare flights from Missouri to the Czech Republic that are best for you.

Fly from

Missouri

Fly to

Czech Republic

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 11/9

6:43 pm-4:05 pm

2 stops14h 22m

Václav Havel Prague

Sun 11/23

7:25 am-1:55 pm

1 stop13h 30m

$483

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 11/9

4:05 pm-2:15 pm

2 stops39h 10m

Václav Havel Prague

Sun 11/23

9:40 am-3:29 pm

2 stops36h 49m

$543

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 11/12

10:00 am-1:05 pm

2 stops20h 05m

Václav Havel Prague

Wed 11/26

7:30 am-1:55 pm

1 stop13h 25m

$545

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 11/12

3:50 pm-6:05 pm

1 stop19h 15m

Václav Havel Prague

Wed 11/26

7:30 am-1:55 pm

1 stop13h 25m

$549

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Mon 2/9

3:11 pm-10:25 pm

2 stops24h 14m

Václav Havel Prague

Fri 2/20

7:35 am-3:29 pm

2 stops38h 54m

$553

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 11/13

5:30 pm-4:05 pm

2 stops15h 35m

Václav Havel Prague

Sun 11/23

7:25 am-8:47 pm

2 stops20h 22m

$555

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 11/14

6:43 pm-10:25 pm

2 stops20h 42m

Václav Havel Prague

Sun 11/23

7:25 am-8:47 pm

2 stops20h 22m

$555

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 11/16

3:25 pm-1:05 pm

2 stops14h 40m

Václav Havel Prague

Tue 11/25

7:25 am-10:28 pm

2 stops22h 03m

$555

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 11/13

9:58 am-1:05 pm

2 stops20h 07m

Václav Havel Prague

Fri 11/21

7:35 am-10:28 pm

2 stops21h 53m

$555

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sat 11/15

5:30 pm-4:05 pm

2 stops15h 35m

Václav Havel Prague

Mon 11/24

7:35 am-9:50 pm

2 stops21h 15m

$555

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/1

Showing 1-10 of 30 results
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Best time to book a flight from Missouri to Czech Republic

Have a flexible travel schedule? Discover the best time to fly to Czech Republic from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to the Czech Republic

What is the cheapest month to book a flight from Missouri to Czech Republic?

Currently, November is the cheapest month in which you can book a flight from Missouri to Czech Republic (average of $651). Flying from Missouri to Czech Republic in June is currently the most expensive (average of $1,118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to CZ?

Find hourly flight availability from Missouri to Czech Republic. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Czech Republic as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Czech Republic. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Czech Republic?

    Departing from Missouri to Czech Republic will take you 14h 22m. There are 4783 mi between Missouri and Czech Republic. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Missouri to Czech Republic one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $440. United Airlines flights start at $449 while deals on Lufthansa start at $458 one-way.

  • Can I find deals for flights from Missouri to Czech Republic that include hotel bookings?

    Yes. In addition to deals on Missouri to Czech Republic flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Czech Republic?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Czech Republic.

  • Can I find deals for business class flights from Missouri to Czech Republic?

    Yes. Cheapflights offers flight deals from Missouri to Czech Republic by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Czech Republic?

    Currently, November is the cheapest month in which you can book a flight from Missouri to Czech Republic (average of $651). Flying from Missouri to Czech Republic in June is currently the most expensive (average of $1,118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Czech Republic

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Czech Republic

Discover the top 7 airlines that operate flights from Missouri to Czech Republic. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$565Average$1,086FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$596Average$976FlexibilityNo cancel feeOn-time69%
DeltaCheapest$628Average$1,188FlexibilityNo cancel feeOn-timeN/A
LufthansaCheapest$639Average$1,094FlexibilityNo cancel feeOn-time76%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%
British AirwaysCheapest$752Average$808FlexibilityNo cancel feeOn-time70%

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