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Cuzco

$961+ Cheap flights from St. Louis (STL) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/24. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
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Cheap flight deals from St. Louis to Cuzco

Best flights from St. Louis to Cuzco
Discover carefully curated flight deals from St. Louis to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:22 amSTL - CUZ
2 stops19h 04mAmerican Airlines
Fri 4/310:25 pmCUZ - STL
2 stops19h 15mAmerican Airlines
Deal found 12/26$961
This KAYAK deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:05 pmSTL - CUZ
2 stops15h 40mLATAM Airlines
Mon 6/296:50 amCUZ - STL
2 stops16h 48mLATAM Airlines
Deal found 12/26$994
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/99:59 amSTL - CUZ
2 stops13h 46mDelta
Mon 2/167:30 pmCUZ - STL
2 stops16h 32mDelta
Deal found 12/26$1,015
This Gotogate deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/94:05 pmSTL - CUZ
3 stops24h 50mMultiple Airlines
Mon 2/167:35 amCUZ - STL
3 stops32h 54mMultiple Airlines
Deal found 12/26$1,603
This American Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1710:00 amSTL - CUZ
2 stops20h 30mAmerican Airlines
Sun 4/268:55 pmCUZ - STL
2 stops20h 36mAmerican Airlines
Deal found 12/26$961
This KAYAK deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/285:00 pmSTL - CUZ
2 stops20h 05mLATAM Airlines
Wed 4/85:00 amCUZ - STL
2 stops18h 58mLATAM Airlines
Deal found 12/26$1,014
This LATAM Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/23:45 pmSTL - CUZ
2 stops19h 50mLATAM Airlines
Thu 2/58:10 pmCUZ - STL
2 stops13h 43mLATAM Airlines
Deal found 12/25$1,172
This Mytrip deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:05 pmSTL - CUZ
2 stops18h 55mMultiple Airlines
Sun 4/269:00 pmCUZ - STL
3 stops42h 24mMultiple Airlines
Deal found 12/26$1,620

Find flight deals from St. Louis to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$961
(American Airlines)

Popular in

November

Cheapest in

December

Average price

$885
Provider with most accurate pricing for Lambert-St Louis-Cusco Velazco Astete flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Cusco Velazco Astete flights.
Search Deals
From Lambert-St Louis to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.

Fly from

St. Louis

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/24

11:22 am-6:26 am

2 stops19h 04m

Cusco Velazco Astete

Fri 4/3

10:25 pm-5:40 pm

2 stops19h 15m

$961

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Fri 4/17

10:00 am-6:30 am

2 stops20h 30m

Cusco Velazco Astete

Sun 4/26

8:55 pm-5:31 pm

2 stops20h 36m

$961

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 6/1

7:05 pm-10:45 am

2 stops15h 40m

Cusco Velazco Astete

Mon 6/29

6:50 am-11:38 pm

2 stops16h 48m

$994

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 3/28

5:00 pm-1:05 pm

2 stops20h 05m

Cusco Velazco Astete

Wed 4/8

5:00 am-11:58 pm

2 stops18h 58m

$1,014

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 2/9

9:59 am-12:45 am

2 stops13h 46m

Cusco Velazco Astete

Mon 2/16

7:30 pm-11:02 am

2 stops16h 32m

$1,015

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 2/2

3:45 pm-12:35 pm

2 stops19h 50m

Cusco Velazco Astete

Thu 2/5

8:10 pm-8:53 am

2 stops13h 43m

$1,172

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 2/9

4:05 pm-5:55 pm

3 stops24h 50m

Cusco Velazco Astete

Mon 2/16

7:35 am-3:29 pm

3 stops32h 54m

$1,603

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Fri 4/17

4:05 pm-11:00 am

2 stops18h 55m

Cusco Velazco Astete

Sun 4/26

9:00 pm-3:24 pm

3 stops42h 24m

$1,620

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/26

Compare providers for flights from St. Louis to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated December 28, 2025.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,895 reviews

Entertainment

7.0

Crew

8.0

Overall

7.5

Comfort

7.3

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP
LATAM Airlines
7.5
Good
1,895 reviews
LATAM Airlines
7.5
Good
1,895 reviews

Entertainment

7.0

Crew

8.0

Overall

7.5

Comfort

7.3

Boarding

7.6

Food

6.7

Reviews

1 / 20
2.0
Mediocre

Anonymous,Oct 2025

MIA - GRU

Terrible baggage service! Almost lost my connection flight in SP

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Cusco?

    There are many flights that can get you from St. Louis to Cusco in 15h 40m. Fly via American Airlines or LATAM Airlines to get the fastest option. There are 3801 mi between St. Louis and Cusco. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from St. Louis to Cusco round-trip?

    Our cheapest airline available from St. Louis to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $803 on this airline. LATAM Airlines is currently priced 26% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Cuzco that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cuzco.

  • Can I find deals for business class flights from St. Louis to Cuzco?

    Yes. Cheapflights offers flight deals from St. Louis to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from St. Louis to Cuzco

Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$803Average$1,067FlexibilityNo cancel feeOn-time81%

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