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$721+ Cheap flights from St. Louis (STL) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from St. Louis to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$721
(United)

Popular in

July

Cheapest in

December
Provider with most accurate pricing for Lambert-St Louis-Cusco Velazco Astete flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Cusco Velazco Astete flights.
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From Lambert-St Louis to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($121 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($30 potential savings vs. average RT price).
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Find flight deals from St. Louis to Cuzco

Cheapest flights from St. Louis to Cuzco
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This KAYAK deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:30 amSTL - CUZ
2 stops28h 50mLATAM Airlines
Sun 12/2111:20 pmCUZ - STL
2 stops25h 22mLATAM Airlines
Deal found 11/11$1,001
This KAYAK deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/121:57 pmSTL - CUZ
2 stops26h 23mLATAM Airlines
Sun 12/2112:05 amCUZ - STL
2 stops24h 37mLATAM Airlines
Deal found 11/13$1,076
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/174:05 pmSTL - CUZ
3 stops31h 35mMultiple Airlines
Mon 12/17:10 amCUZ - STL
3 stops33h 19mMultiple Airlines
Deal found 11/11$1,173
This LATAM Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/611:19 amSTL - CUZ
2 stops20h 46mLATAM Airlines
Mon 12/812:05 amCUZ - STL
2 stops22h 52mLATAM Airlines
Deal found 11/11$1,214

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.

Fly from

St. Louis

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 4/7

6:00 am-11:00 am

2 stops29h 00m

Cusco Velazco Astete

Fri 4/17

12:15 pm-11:50 pm

2 stops35h 35m

$721

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/31

5:03 pm-3:54 pm

2 stops22h 51m

Cusco Velazco Astete

Thu 4/9

6:57 am-9:16 am

2 stops26h 19m

$936

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Wed 4/1

5:03 pm-4:44 pm

2 stops23h 41m

Cusco Velazco Astete

Wed 4/8

4:27 pm-9:16 am

2 stops16h 49m

$936

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 3/30

5:03 pm-7:26 am

2 stops14h 23m

Cusco Velazco Astete

Thu 4/9

3:57 pm-9:16 am

2 stops17h 19m

$936

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 3/29

5:03 pm-7:26 am

2 stops38h 23m

Cusco Velazco Astete

Thu 4/9

5:17 pm-9:16 am

2 stops15h 59m

$949

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 3/29

5:03 pm-7:26 am

2 stops38h 23m

Cusco Velazco Astete

Tue 4/7

4:42 pm-9:16 am

2 stops16h 34m

$949

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 3/29

5:03 pm-7:26 am

2 stops38h 23m

Cusco Velazco Astete

Mon 4/6

10:22 pm-5:31 pm

2 stops19h 09m

$949

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/31

5:03 pm-7:24 am

2 stops14h 21m

Cusco Velazco Astete

Fri 4/10

10:22 pm-9:35 pm

2 stops23h 13m

$962

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 3/30

5:03 pm-7:26 am

2 stops14h 23m

Cusco Velazco Astete

Fri 4/10

10:22 pm-9:35 pm

2 stops23h 13m

$962

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 3/24

11:30 am-10:26 am

2 stops22h 56m

Cusco Velazco Astete

Fri 4/3

11:47 am-10:29 am

2 stops22h 42m

$962

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Compare providers for flights from St. Louis to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as Delta and LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,875 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Crew

8.5

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Cusco?

    There are many flights that can get you from St. Louis to Cusco in 22h 51m. Fly via American Airlines to get the fastest option. There are 3801 mi between St. Louis and Cusco.

  • What are the cheapest airlines flying from St. Louis to Cusco round-trip?

    Our cheapest airline available from St. Louis to Cusco is Delta. Our recent data shows that you can find tickets from as low as $733 on this airline. An additional option worth looking into is LATAM Airlines, starting at $796. Delta is currently priced 31% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Cuzco that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cuzco.

  • Can I find deals for business class flights from St. Louis to Cuzco?

    Yes. Cheapflights offers flight deals from St. Louis to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from St. Louis to Cuzco

Discover the top 2 airlines that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$733Average$1,232FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$796Average$1,002FlexibilityNo cancel feeOn-time81%

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