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$936+ Cheap flights from St. Louis (STL) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from St. Louis to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$936
(LATAM Airlines)

Popular in

December

Cheapest in

March

Average price

$1,140
From Lambert-St Louis to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($382 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($59 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from St. Louis to Cuzco

Cheapest flights from St. Louis to Cuzco
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This LATAM Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:52 pmSTL - CUZ
2 stops17h 38mLATAM Airlines
Tue 10/286:55 pmCUZ - STL
2 stops15h 31mLATAM Airlines
Deal found 8/14$936
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:52 pmSTL - CUZ
2 stops14h 08mLATAM Airlines
Sun 10/265:00 amCUZ - STL
2 stops18h 41mLATAM Airlines
Deal found 8/13$960
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/305:21 amSTL - CUZ
2 stops24h 35mAmerican Airlines
Sun 12/149:02 pmCUZ - STL
2 stops19h 35mAmerican Airlines
Deal found 8/13$962
This FlightHub deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:00 amSTL - CUZ
2 stops18h 45mLATAM Airlines
Sat 10/256:55 amCUZ - STL
2 stops25h 10mLATAM Airlines
Deal found 8/13$963
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/275:28 amSTL - CUZ
2 stops15h 56mAmerican Airlines
Sat 10/48:57 pmCUZ - STL
2 stops27h 02mAmerican Airlines
Deal found 8/13$988
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/94:21 pmSTL - CUZ
2 stops47h 05mAmerican Airlines
Thu 11/1311:02 amCUZ - STL
2 stops29h 48mAmerican Airlines
Deal found 8/13$1,018
This Orbitz deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/309:00 amSTL - CUZ
2 stops14h 45mLATAM Airlines
Sat 12/1312:05 amCUZ - STL
2 stops24h 34mLATAM Airlines
Deal found 8/13$1,065
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/174:05 pmSTL - CUZ
2 stops18h 55mMultiple Airlines
Sat 10/256:57 amCUZ - STL
3 stops27h 05mMultiple Airlines
Deal found 8/13$1,195
This Mytrip deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:05 pmSTL - CUZ
2 stops18h 55mMultiple Airlines
Sat 10/48:02 amCUZ - STL
3 stops26h 00mMultiple Airlines
Deal found 8/13$1,594
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/164:25 pmSTL - CUZ
3 stops14h 54mAmerican Airlines
Tue 10/2810:02 pmCUZ - STL
2 stops25h 54mAmerican Airlines
Deal found 8/14$1,947

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.

Fly from

St. Louis

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Thu 10/16

5:15 pm-9:25 am

2 stops16h 10m

Cusco Velazco Astete

Tue 10/28

1:15 pm-12:35 pm

2 stops23h 20m

$936

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Fri 10/17

6:52 pm-9:00 am

2 stops14h 08m

Cusco Velazco Astete

Sun 10/26

5:00 am-11:41 pm

2 stops18h 41m

$960

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 11/30

5:21 am-6:56 am

2 stops24h 35m

Cusco Velazco Astete

Sun 12/14

9:02 pm-3:37 pm

2 stops19h 35m

$962

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Fri 10/17

6:52 pm-9:15 am

2 stops14h 23m

Cusco Velazco Astete

Sat 10/25

6:55 am-8:05 am

2 stops25h 10m

$963

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 9/27

5:28 am-9:24 pm

2 stops15h 56m

Cusco Velazco Astete

Sat 10/4

8:57 pm-11:59 pm

2 stops27h 02m

$988

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 11/9

4:21 pm-9:26 pm

2 stops52h 05m

Cusco Velazco Astete

Thu 11/13

11:02 am-3:50 pm

2 stops29h 48m

$1,018

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 11/30

9:00 am-12:45 am

2 stops14h 45m

Cusco Velazco Astete

Sat 12/13

12:05 am-11:39 pm

2 stops24h 34m

$1,065

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Fri 10/17

4:05 pm-11:00 am

2 stops18h 55m

Cusco Velazco Astete

Sat 10/25

6:57 am-10:02 am

3 stops27h 05m

$1,195

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Best time to book a flight from St. Louis to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Cusco

What is the cheapest month to book a flight from St. Louis to Cusco?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated August 14, 2025.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,840 reviews

Crew

8.0

Comfort

7.4

Boarding

7.6

Overall

7.5

Entertainment

7.0

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,840 reviews
LATAM Airlines
7.5
Good
1,840 reviews

Crew

8.0

Comfort

7.4

Boarding

7.6

Overall

7.5

Entertainment

7.0

Food

6.7

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from St. Louis to Cusco round-trip?

    Our cheapest airline available from St. Louis to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $796 on this airline. LATAM Airlines is currently priced 31% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Cuzco that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cuzco.

  • Can I find deals for business class flights from St. Louis to Cuzco?

    Yes. Cheapflights offers flight deals from St. Louis to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cusco?

    Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from St. Louis to Cuzco

Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$796Average$969FlexibilityNo cancel feeOn-time81%

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