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Cuzco

$423+ Cheap flights from St. Louis (STL) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from St. Louis to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$763
(LATAM Airlines)

One-way from

$423
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$1,042
From Lambert-St Louis to Cusco Velazco Astete
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One-way flight from Lambert-St Louis to Cusco Velazco Astete
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Highest demand for flights based on searches. 32% potential increase in price ($558 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($106 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from St. Louis to Cuzco

Cheapest flights from St. Louis to Cuzco
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This LATAM Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/223:30 pmSTL - CUZ
2 stops21h 20mLATAM Airlines
Mon 9/295:55 pmCUZ - STL
2 stops16h 45mLATAM Airlines
Deal found 6/9$763
This Mytrip deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:37 pmSTL - CUZ
3 stops35h 47mMultiple Airlines
Sat 10/2511:30 amCUZ - STL
3 stops31h 02mMultiple Airlines
Deal found 6/9$878
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/266:00 amSTL - CUZ
2 stops18h 45mDelta
Fri 10/318:00 pmCUZ - STL
2 stops16h 25mDelta
Deal found 6/11$981
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:28 amSTL - CUZ
2 stops24h 56mAmerican Airlines
Sat 9/2710:02 pmCUZ - STL
2 stops25h 57mAmerican Airlines
Deal found 6/11$987

Cheapflights Fare Finder

Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.

Fly from

St. Louis

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 9/22

3:30 pm-12:50 pm

2 stops21h 20m

Cusco Velazco Astete

Mon 9/29

5:55 pm-10:40 am

2 stops16h 45m

$763

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 10/18

7:37 pm-7:24 am

3 stops35h 47m

Cusco Velazco Astete

Sat 10/25

11:30 am-6:32 pm

3 stops31h 02m

$878

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sun 10/26

6:00 am-12:45 am

2 stops18h 45m

Cusco Velazco Astete

Fri 10/31

8:00 pm-12:25 pm

2 stops16h 25m

$981

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 9/20

5:28 am-6:24 am

2 stops24h 56m

Cusco Velazco Astete

Sat 9/27

10:02 pm-11:59 pm

2 stops25h 57m

$987

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Tue 10/28

7:37 pm-6:45 am

3 stops35h 08m

$423

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from St. Louis to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Cusco

What is the cheapest month to book a flight from St. Louis to Cusco?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Cuzco by month

Plan your trip to Cuzco by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

Temperature in Cuzco by month

Plan your trip to Cuzco by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from St. Louis to Cusco round-trip?

    Our cheapest airline available from St. Louis to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $763 on this airline. Additional options worth looking into are Delta and American Airlines, starting at $981 and $987 round-trip. LATAM Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Cuzco that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cuzco.

  • Can I find deals for business class flights from St. Louis to Cuzco?

    Yes. Cheapflights offers flight deals from St. Louis to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cusco?

    Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from St. Louis to Cuzco

Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$771Average$965FlexibilityNo cancel feeOn-time81%

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