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Cuzco

$754+ Cheap flights from St. Louis (STL) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CUZ
Oct 25 — Nov 11
Sat 10/25
Sat 11/1
1 adult, Economy
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Cheap flight deals from St. Louis to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 25, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$754
(United)

Popular in

November

Cheapest in

March

Average price

$1,052
Provider with most accurate pricing for Lambert-St Louis-Cusco Velazco Astete flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Cusco Velazco Astete flights.
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From Lambert-St Louis to Cusco Velazco Astete
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Highest demand for flights based on searches. 8% potential increase in price ($100 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from St. Louis to Cuzco

Cheapest flights from St. Louis to Cuzco
Explore the most affordable flight options available from St. Louis to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2025.

This Mytrip deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/257:15 pmSTL - CUZ
3 stops35h 00mMultiple Airlines
Mon 11/37:32 amCUZ - STL
3 stops32h 57mMultiple Airlines
Deal found 9/25$842
This LATAM Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1611:21 amSTL - CUZ
2 stops13h 14mLATAM Airlines
Tue 10/286:35 pmCUZ - STL
2 stops23h 27mLATAM Airlines
Deal found 9/23$918
This Mytrip deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/89:15 amSTL - CUZ
3 stops35h 30mMultiple Airlines
Sat 10/116:47 amCUZ - STL
3 stops27h 15mMultiple Airlines
Deal found 9/24$941
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:15 amSTL - CUZ
2 stops24h 11mAmerican Airlines
Mon 11/178:57 pmCUZ - STL
2 stops20h 14mAmerican Airlines
Deal found 9/25$962
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:00 amSTL - CUZ
2 stops18h 40mDelta
Mon 11/38:15 pmCUZ - STL
2 stops22h 47mDelta
Deal found 9/25$983
This LATAM Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amSTL - CUZ
2 stops18h 35mLATAM Airlines
Tue 10/146:40 amCUZ - STL
2 stops25h 25mLATAM Airlines
Deal found 9/23$1,000
This Orbitz deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2510:30 amSTL - CUZ
2 stops34h 50mLATAM Airlines
Sun 11/212:05 amCUZ - STL
2 stops35h 21mLATAM Airlines
Deal found 9/25$1,013
This LATAM Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/86:00 amSTL - CUZ
2 stops18h 35mLATAM Airlines
Sat 10/116:55 amCUZ - STL
2 stops25h 10mLATAM Airlines
Deal found 9/24$1,043
This Orbitz deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:59 pmSTL - CUZ
2 stops16h 01mLATAM Airlines
Sun 11/1612:05 amCUZ - STL
2 stops24h 35mLATAM Airlines
Deal found 9/25$1,052
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/94:41 pmSTL - CUZ
2 stops46h 50mAmerican Airlines
Thu 11/135:07 pmCUZ - STL
2 stops24h 04mAmerican Airlines
Deal found 9/22$1,093
This LATAM Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/169:30 amSTL - CUZ
2 stops14h 15mLATAM Airlines
Tue 12/305:00 amCUZ - STL
2 stops19h 39mLATAM Airlines
Deal found 9/23$1,156

Cheapflights Fare Finder

 
Customize your flight search to find flights from St. Louis to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
Use the filters below to find and compare flights from St. Louis to Cusco that are best for you.

Fly from

St. Louis

Fly to

Cuzco

Route

Depart

Return

Price

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Mon 2/16

6:00 am-11:20 am

2 stops28h 20m

Cusco Velazco Astete

Sun 2/22

12:25 pm-9:23 am

2 stops45h 58m

$754

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 10/25

7:15 pm-6:15 am

3 stops35h 00m

Cusco Velazco Astete

Mon 11/3

7:32 am-3:29 pm

3 stops32h 57m

$842

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Thu 10/16

6:00 am-12:35 am

2 stops18h 35m

Cusco Velazco Astete

Tue 10/28

9:50 am-10:26 am

2 stops24h 36m

$918

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Wed 10/8

9:15 am-8:45 pm

3 stops35h 30m

Cusco Velazco Astete

Sat 10/11

6:47 am-10:02 am

3 stops27h 15m

$941

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 11/8

5:15 am-6:26 am

2 stops24h 11m

Cusco Velazco Astete

Mon 11/17

8:57 pm-4:11 pm

2 stops20h 14m

$962

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 10/25

6:00 am-12:40 am

2 stops18h 40m

Cusco Velazco Astete

Mon 11/3

8:15 pm-6:02 pm

2 stops22h 47m

$983

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Wed 10/8

6:00 am-12:35 am

2 stops18h 35m

Cusco Velazco Astete

Tue 10/14

6:40 am-8:05 am

2 stops25h 25m

$1,000

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 10/25

10:30 am-9:20 pm

2 stops34h 50m

Cusco Velazco Astete

Sun 11/2

12:05 am-10:26 am

2 stops35h 21m

$1,013

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Sat 1/17

10:00 am-9:00 am

2 stops22h 00m

Cusco Velazco Astete

Sun 1/25

12:05 am-11:40 pm

2 stops24h 35m

$1,028

St. LouisCusco

STL - CUZ

STLCUZ

Lambert-St Louis

Wed 10/8

6:00 am-12:35 am

2 stops18h 35m

Cusco Velazco Astete

Sat 10/11

6:55 am-8:05 am

2 stops25h 10m

$1,043

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/23

Compare providers for flights from St. Louis to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Cuzco in September.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on St. Louis-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on St. Louis-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from St. Louis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Cusco

What is the cheapest month to book a flight from St. Louis to Cusco?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated September 25, 2025.
Read through reviews of airlines operating flights from St. Louis to Cusco, such as LATAM Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,855 reviews

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Food

6.7

Reviews

1 / 20
8.0
Excellent

Juan Carlos,Sep 2025

MVD - SCL

My experience was good but on my way back from LA to Vegas when I was boarding I was pulled to the side and I was asked to show my passport, I ‘am an American Citizen since 2001. I was the only one who was asked, there was no reason for that. Other that it was a good experience.
LATAM Airlines
7.5
Good
1,855 reviews
LATAM Airlines
7.5
Good
1,855 reviews

Crew

8.1

Overall

7.5

Comfort

7.4

Boarding

7.6

Entertainment

7.0

Food

6.7

Reviews

1 / 20
8.0
Excellent

Juan Carlos,Sep 2025

MVD - SCL

My experience was good but on my way back from LA to Vegas when I was boarding I was pulled to the side and I was asked to show my passport, I ‘am an American Citizen since 2001. I was the only one who was asked, there was no reason for that. Other that it was a good experience.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from St. Louis to Cusco?

    There are many flights that can get you from St. Louis to Cusco in 18h 35m. Fly via LATAM Airlines to get the fastest option. There are 3801 mi between St. Louis and Cusco.

  • What is the cheapest airline to fly from St. Louis to Cusco round-trip?

    Our cheapest airline available from St. Louis to Cusco is LATAM Airlines. Our recent data shows that you can find tickets from as low as $796 on this airline. LATAM Airlines is currently priced 28% below the average price you’ll pay for this route.

  • Can I find deals for flights from St. Louis to Cuzco that include hotel bookings?

    Yes. In addition to deals on St. Louis to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from St. Louis to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Cuzco.

  • Can I find deals for business class flights from St. Louis to Cuzco?

    Yes. Cheapflights offers flight deals from St. Louis to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from St. Louis to Cusco?

    Currently, February is the cheapest month in which you can book a flight from St. Louis to Cusco (average of $789). Flying from St. Louis to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from St. Louis to Cuzco

Discover the top airline that operate flights from St. Louis to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 25, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$796Average$973FlexibilityNo cancel feeOn-time81%

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