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$263+ Cheap flights from South Carolina to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/9. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from South Carolina to Cuzco

Keep the following information in mind while searching for South Carolina to Cuzco flight deals. Data was last updated November 3, 2025.

Round-trip from

$677
(United)

One-way from

$263
(Kiwi.com)
From South Carolina to Cusco Velazco Astete
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One-way flight from South Carolina to Cusco Velazco Astete
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Find flight deals from South Carolina to Cuzco

Cheapest flights from South Carolina to Cuzco
Explore the most affordable flight options available from South Carolina to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Mytrip deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/178:55 amCLT - CUZ
2 stops21h 31mMultiple Airlines
Wed 12/246:30 pmCUZ - CLT
3 stops26h 09mMultiple Airlines
Deal found 11/2$733
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:34 pmCLT - CUZ
3 stops32h 52mMultiple Airlines
Wed 12/316:30 pmCUZ - CLT
2 stops15h 09mMultiple Airlines
Deal found 11/3$780
This LATAM Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:00 amCHS - CUZ
2 stops16h 45mLATAM Airlines
Tue 12/97:30 amCUZ - CHS
2 stops16h 20mLATAM Airlines
Deal found 11/2$1,032
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:31 pmSAV - CUZ
2 stops19h 55mAmerican Airlines
Wed 12/108:57 pmCUZ - SAV
2 stops13h 07mAmerican Airlines
Deal found 11/2$1,050
This Priceline deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:53 pmCLT - CUZ
2 stops27h 52mLATAM Airlines
Tue 12/3012:05 amCUZ - CLT
2 stops23h 41mLATAM Airlines
Deal found 11/3$1,240
This Expedia deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:12 pmCLT - CUZ
2 stops31h 13mLATAM Airlines
Tue 12/2312:05 amCUZ - CLT
2 stops23h 41mLATAM Airlines
Deal found 11/2$1,338

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from South Carolina to Cusco that are best for you.

Fly from

South Carolina

Fly to

Cuzco

Route

Depart

Return

Price

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Thu 3/12

7:00 am-11:20 am

2 stops29h 20m

Cusco Velazco Astete

Fri 3/20

12:25 pm-9:42 pm

2 stops32h 17m

$677

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Wed 12/17

8:55 am-6:26 am

2 stops21h 31m

Cusco Velazco Astete

Wed 12/24

6:30 pm-8:39 pm

3 stops26h 09m

$733

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Fri 12/26

9:34 pm-6:26 am

3 stops32h 52m

Cusco Velazco Astete

Wed 12/31

6:30 pm-9:39 am

2 stops15h 09m

$780

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Mon 3/30

2:32 pm-7:26 am

2 stops17h 54m

Cusco Velazco Astete

Thu 4/2

3:57 pm-12:11 pm

2 stops19h 14m

$892

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Mon 3/30

11:45 am-6:35 am

2 stops19h 50m

Cusco Velazco Astete

Thu 4/2

7:45 pm-11:05 am

2 stops14h 20m

$892

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Thu 3/5

11:00 am-6:26 am

2 stops19h 26m

Cusco Velazco Astete

Tue 3/17

4:37 pm-10:30 am

2 stops16h 53m

$892

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Fri 3/20

7:50 am-5:55 pm

2 stops35h 05m

Cusco Velazco Astete

Sat 3/28

8:17 pm-9:00 pm

3 stops23h 43m

$954

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 12/6

11:15 am-6:15 am

2 stops19h 00m

Cusco Velazco Astete

Tue 12/9

7:30 am-11:50 pm

2 stops16h 20m

$1,032

SavannahCusco

SAV - CUZ

SAVCUZ

Savannah/Hilton Head

Mon 12/8

10:57 am-7:26 am

2 stops20h 29m

Cusco Velazco Astete

Wed 12/10

12:52 pm-10:04 am

2 stops21h 12m

$1,050

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Fri 1/9

10:32 am-7:20 am

2 stops44h 48m

$263

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/2

Showing 1-10 of 13 results
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Best time to book a flight from South Carolina to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cusco

What is the cheapest time of day to fly from SC to CUZ?

Find hourly flight availability from South Carolina to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

When flying from South Carolina to Cusco, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 46% versus a flight at noon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from South Carolina?

    For a flight from South Carolina to Cusco, you will be flying into Velazco Astete. Cusco Velazco Astete (CUZ) is just 1.7 mi from the center of the city.

  • How long is the flight from South Carolina to Cusco?

    For as low as $1,032, LATAM Airlines can have you in Cusco from South Carolina in 19h. The distance from South Carolina to Cusco is about 3250 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Cusco?

    The most popular route from South Carolina to Cusco is Charlotte Douglas - Cusco Velazco Astete. You may also consider Charleston - Cusco Velazco Astete or Savannah/Hilton Head - Cusco Velazco Astete.

  • Can I find deals for flights from South Carolina to Cuzco that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cuzco.

  • Can I find deals for business class flights from South Carolina to Cuzco?

    Yes. Cheapflights offers flight deals from South Carolina to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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