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Cuzco

$441+ Cheap flights from South Carolina to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Mar 15 — Mar 221
Sun 3/15
Sun 3/22
1 adult, Economy
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Cheap flight deals from South Carolina to Cuzco

Cheapest flights from South Carolina to Cuzco
Explore the most affordable flight options available from South Carolina to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 13, 2026.

This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/158:07 am
CHS
-
CUZ
2 stops23h 18m
Multiple Airlines
Sun 3/227:02 am
CUZ
-
CHS
3 stops38h 11m
Multiple Airlines
Deal found 2/13$760
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/297:00 am
CLT
-
CUZ
3 stops25h 50m
Multiple Airlines
Sun 4/128:55 pm
CUZ
-
CLT
2 stops14h 12m
Multiple Airlines
Deal found 2/11$775
This Mytrip deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:00 am
CLT
-
CUZ
3 stops34h 55m
Multiple Airlines
Thu 2/269:45 pm
CUZ
-
CLT
2 stops14h 35m
Multiple Airlines
Deal found 2/13$787
This KAYAK deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:10 pm
CHS
-
CUZ
2 stops11h 16m
GOL
Thu 9/2411:02 am
CUZ
-
CHS
2 stops22h 18m
GOL
Deal found 2/13$869
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:20 pm
CLT
-
CUZ
2 stops18h 10m
Multiple Airlines
Tue 4/710:45 am
CUZ
-
CLT
3 stops26h 07m
Multiple Airlines
Deal found 2/11$876
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:39 am
CHS
-
CUZ
2 stops13h 42m
American Airlines
Thu 9/2412:02 pm
CUZ
-
CHS
2 stops21h 18m
American Airlines
Deal found 2/13$890
This KAYAK deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/124:30 pm
CLT
-
CUZ
2 stops15h 55m
GOL
Wed 5/209:50 pm
CUZ
-
CLT
2 stops20h 53m
GOL
Deal found 2/9$896
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
American Airlines
Sun 6/710:05 pm
CUZ
-
CHS
2 stops20h 23m
American Airlines
Deal found 2/11$916
This KAYAK deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:30 pm
CLT
-
CUZ
2 stops24h 50m
LATAM Airlines
Wed 5/208:25 am
CUZ
-
CLT
2 stops14h 28m
LATAM Airlines
Deal found 2/10$919
This BusinessClass deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/97:59 pm
CLT
-
CUZ
3 stops29h 41m
LATAM Airlines
Wed 8/198:25 am
CUZ
-
CLT
2 stops14h 32m
LATAM Airlines
Deal found 2/11$923
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
American Airlines
Fri 6/510:25 pm
CUZ
-
CHS
2 stops24h 30m
American Airlines
Deal found 2/11$942
This KAYAK deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:08 pm
CHS
-
CUZ
2 stops26h 02m
GOL
Sat 6/69:40 pm
CUZ
-
CHS
2 stops25h 15m
GOL
Deal found 2/11$945

Find flight deals from South Carolina to Cuzco

Keep the following information in mind while searching for South Carolina to Cuzco flight deals. Data was last updated February 13, 2026.

Round-trip from

$760
(Mytrip)

One-way from

$441
(Kiwi.com)
From South Carolina to Cusco Velazco Astete
Search Deals
One-way flight from South Carolina to Cusco Velazco Astete
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 13, 2026.
Use the filters below to find and compare flights from South Carolina to Cusco that are best for you.

Fly from

South Carolina

Fly to

Cuzco

Route

Depart

Return

Price

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 3/15

8:07 am-6:25 am

2 stops23h 18m

Cusco Velazco Astete

Sun 3/22

7:02 am-10:13 pm

3 stops38h 11m

$760

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Sun 3/29

7:00 am-7:50 am

3 stops25h 50m

Cusco Velazco Astete

Sun 4/12

8:55 pm-12:07 pm

2 stops14h 12m

$775

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Thu 2/19

7:00 am-5:55 pm

3 stops34h 55m

Cusco Velazco Astete

Thu 2/26

9:45 pm-12:20 pm

2 stops14h 35m

$787

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Fri 4/3

1:20 pm-6:30 am

2 stops18h 10m

Cusco Velazco Astete

Tue 4/7

10:45 am-1:52 pm

3 stops26h 07m

$876

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Tue 5/12

4:30 pm-7:25 am

2 stops15h 55m

Cusco Velazco Astete

Wed 5/20

9:50 pm-7:43 pm

2 stops20h 53m

$896

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 5/24

8:08 pm-9:05 pm

2 stops25h 57m

Cusco Velazco Astete

Sun 6/7

10:05 pm-7:28 pm

2 stops20h 23m

$916

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Tue 5/12

5:30 pm-5:20 pm

2 stops24h 50m

Cusco Velazco Astete

Wed 5/20

8:25 am-11:53 pm

2 stops14h 28m

$919

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 5/23

8:08 pm-9:10 pm

2 stops26h 02m

Cusco Velazco Astete

Fri 6/5

10:25 pm-11:55 pm

2 stops24h 30m

$942

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sun 5/24

8:08 pm-9:05 pm

2 stops25h 57m

Cusco Velazco Astete

Fri 6/5

10:48 am-7:28 pm

2 stops31h 40m

$942

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 5/23

8:08 pm-9:10 pm

2 stops26h 02m

Cusco Velazco Astete

Sat 6/6

9:40 pm-11:55 pm

2 stops25h 15m

$945

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/12

Showing 1-10 of 21 results
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Best time to book a flight from South Carolina to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cusco
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from South Carolina?

    For a flight from South Carolina to Cusco, you will be flying into Velazco Astete. Cusco Velazco Astete (CUZ) is just 1.7 mi from the center of the city.

  • How long is the flight from South Carolina to Cusco?

    For as low as $916, American Airlines can have you in Cusco from South Carolina in 25h 57m. The distance from South Carolina to Cusco is about 3250 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Cusco?

    The most popular route from South Carolina to Cusco is Charlotte Douglas - Cusco Velazco Astete. You may also consider Charleston - Cusco Velazco Astete or Savannah/Hilton Head - Cusco Velazco Astete.

  • Can I find deals for flights from South Carolina to Cuzco that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cuzco.

  • Can I find deals for business class flights from South Carolina to Cuzco?

    Yes. Cheapflights offers flight deals from South Carolina to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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