HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Cuzco

$280+ Cheap flights from South Carolina to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/8. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — CUZ
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Cuzco with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Cuzco

Keep the following information in mind while searching for South Carolina to Cuzco flight deals. Data was last updated September 15, 2025.

Round-trip from

$687
(Mytrip)

One-way from

$280
(Kiwi.com)
From South Carolina to Cusco Velazco Astete
Search Deals
One-way flight from South Carolina to Cusco Velazco Astete
Search Deals

Find flight deals from South Carolina to Cuzco

Cheapest flights from South Carolina to Cuzco
Explore the most affordable flight options available from South Carolina to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:22 pmCLT - CUZ
3 stops27h 44mMultiple Airlines
Tue 11/114:37 pmCUZ - CLT
3 stops32h 22mMultiple Airlines
Deal found 9/15$687
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/285:45 amCLT - CUZ
3 stops25h 41mMultiple Airlines
Tue 11/410:02 pmCUZ - CLT
3 stops26h 57mMultiple Airlines
Deal found 9/13$696
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:00 pmCLT - CUZ
2 stops16h 25mDelta
Mon 12/295:00 amCUZ - CLT
2 stops18h 53mDelta
Deal found 9/14$866
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/235:45 amCLT - CUZ
2 stops25h 11mMultiple Airlines
Fri 11/286:30 pmCUZ - CLT
2 stops14h 57mMultiple Airlines
Deal found 9/15$907
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:27 amCHS - CUZ
2 stops20h 59mAmerican Airlines
Thu 12/119:02 amCUZ - CHS
2 stops23h 45mAmerican Airlines
Deal found 9/14$944
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:00 pmCLT - CUZ
2 stops16h 00mDelta
Tue 12/306:50 amCUZ - CLT
2 stops15h 20mDelta
Deal found 9/14$958
This LATAM Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/67:00 amCHS - CUZ
2 stops17h 45mLATAM Airlines
Tue 12/96:50 amCUZ - CHS
2 stops17h 07mLATAM Airlines
Deal found 9/13$970
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/71:13 pmCLT - CUZ
2 stops18h 13mAmerican Airlines
Tue 11/115:07 pmCUZ - CLT
2 stops16h 04mAmerican Airlines
Deal found 9/15$984
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:42 pmCLT - CUZ
2 stops18h 28mDelta
Mon 12/295:00 amCUZ - CLT
2 stops18h 53mDelta
Deal found 9/14$1,005
This Travelocity deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/74:24 pmCHS - CUZ
2 stops32h 21mLATAM Airlines
Mon 11/1012:05 amCUZ - CHS
2 stops23h 52mLATAM Airlines
Deal found 9/15$1,008
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/283:45 pmCLT - CUZ
2 stops15h 41mAmerican Airlines
Tue 11/45:02 pmCUZ - CLT
2 stops17h 40mAmerican Airlines
Deal found 9/13$1,019
This LATAM Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/217:05 pmCHS - CUZ
2 stops17h 50mLATAM Airlines
Sun 10/262:40 pmCUZ - CHS
2 stops18h 40mLATAM Airlines
Deal found 9/14$1,028

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from South Carolina to Cusco that are best for you.

Fly from

South Carolina

Fly to

Cuzco

Route

Depart

Return

Price

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Fri 11/7

5:22 pm-9:06 pm

3 stops27h 44m

Cusco Velazco Astete

Tue 11/11

4:37 pm-12:59 am

3 stops32h 22m

$687

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Tue 10/28

5:45 am-6:26 am

3 stops25h 41m

Cusco Velazco Astete

Tue 11/4

10:02 pm-12:59 am

3 stops26h 57m

$696

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Wed 12/24

5:00 pm-9:25 am

2 stops16h 25m

Cusco Velazco Astete

Mon 12/29

5:00 am-11:53 pm

2 stops18h 53m

$866

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Thu 12/25

5:00 pm-10:45 am

2 stops17h 45m

Cusco Velazco Astete

Mon 12/29

5:00 am-10:10 pm

2 stops17h 10m

$866

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Tue 12/2

9:27 am-6:26 am

2 stops20h 59m

Cusco Velazco Astete

Thu 12/11

9:02 am-8:47 am

2 stops23h 45m

$944

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Wed 12/24

5:00 pm-9:00 am

2 stops16h 00m

Cusco Velazco Astete

Tue 12/30

7:35 am-10:10 pm

2 stops14h 35m

$958

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Wed 12/24

5:00 pm-9:00 am

2 stops16h 00m

Cusco Velazco Astete

Tue 12/30

6:50 am-10:10 pm

2 stops15h 20m

$958

CharlotteCusco

CLT - CUZ

CLTCUZ

Charlotte Douglas

Thu 12/25

5:00 pm-9:25 am

2 stops16h 25m

Cusco Velazco Astete

Tue 12/30

7:35 am-10:10 pm

2 stops14h 35m

$958

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Fri 11/7

7:57 pm-4:46 pm

2 stops20h 49m

Cusco Velazco Astete

Tue 11/11

10:02 pm-7:17 pm

2 stops21h 15m

$970

CharlestonCusco

CHS - CUZ

CHSCUZ

Charleston

Sat 12/6

5:00 pm-12:35 pm

2 stops19h 35m

Cusco Velazco Astete

Tue 12/9

6:50 am-11:57 pm

2 stops17h 07m

$970

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 19 results
1
2

Best time to book a flight from South Carolina to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Cusco

What is the cheapest time of day to fly from SC to CUZ?

Find hourly flight availability from South Carolina to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Cusco as you normally would.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from South Carolina?

    For a flight from South Carolina to Cusco, you will be flying into Velazco Astete. Cusco Velazco Astete (CUZ) is just 1.7 mi from the center of the city.

  • How long is the flight from South Carolina to Cusco?

    For as low as $866, Delta can have you in Cusco from South Carolina in 16h 25m. The distance from South Carolina to Cusco is about 3418 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Cusco?

    The most popular route from South Carolina to Cusco is Charlotte Douglas - Cusco Velazco Astete. You may also consider Charleston - Cusco Velazco Astete or Savannah/Hilton Head - Cusco Velazco Astete.

  • Can I find deals for flights from South Carolina to Cuzco that include hotel bookings?

    Yes. In addition to deals on South Carolina to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Cuzco.

  • Can I find deals for business class flights from South Carolina to Cuzco?

    Yes. Cheapflights offers flight deals from South Carolina to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Cusco?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Cusco (average of $789). Flying from South Carolina to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Lima flights
Miami to Lima flights
Newark to Lima flights
Los Angeles to Lima flights
LaGuardia to Lima flights
Dulles Intl to Lima flights
San Francisco to Lima flights
Reagan-National to Lima flights
Baltimore to Lima flights
Tampa to Lima flights
O'Hare Intl to Lima flights
Atlanta to Lima flights
Dallas/Fort Worth to Lima flights
Fort Lauderdale to Lima flights
Seattle to Lima flights
Orlando to Lima flights
Midway to Lima flights
Boston to Lima flights
Denver to Lima flights
Ontario to Lima flights
Hobby to Lima flights
Austin to Lima flights
John F Kennedy Intl to Cuzco flights
Salt Lake City to Lima flights
Love Field to Lima flights
George Bush Intcntl to Lima flights
Minneapolis to Lima flights
Seattle to Cuzco flights
San Jose to Lima flights
Detroit to Lima flights
Newark to Cuzco flights
Los Angeles to Cuzco flights
Raleigh to Lima flights
Philadelphia to Lima flights
Charlotte to Lima flights
Sky Harbor Intl to Lima flights
Hartford to Lima flights
LaGuardia to Cuzco flights
San Francisco to Cuzco flights
Portland to Lima flights
Dallas/Fort Worth to Cuzco flights
West Palm Beach to Lima flights
Denver to Cuzco flights
Boston to Cuzco flights
Providence to Lima flights
San Diego to Lima flights
Miami to Cuzco flights
New Orleans to Lima flights
O'Hare Intl to Cuzco flights

Top airline flying from South Carolina to Cuzco

Discover the top airline that operate flights from South Carolina to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$725Average$898FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.