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$1,034+ Cheap flights from Panama City, FL (ECP) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CUZ
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
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Cheap flight deals from Panama City to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$1,034
(Delta)
From Panama City NW Florida Beaches to Cusco Velazco Astete
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Find flight deals from Panama City to Cuzco

Cheapest flights from Panama City to Cuzco
Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/66:00 amECP - CUZ
2 stops17h 45mDelta
lun. 12/87:50 pmCUZ - ECP
2 stops17h 57mDelta
Deal found 9/11$1,034
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/117:10 amECP - CUZ
2 stops17h 25mDelta
lun. 10/137:00 pmCUZ - ECP
2 stops15h 19mDelta
Deal found 9/11$2,494
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/63:20 pmECP - CUZ
3 stops18h 06mAmerican Airlines
lun. 12/88:57 pmCUZ - ECP
3 stops18h 50mAmerican Airlines
Deal found 9/11$2,884

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Panama City

Fly to

Cuzco

Route

Depart

Return

Price

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

sáb. 12/6

7:02 am-12:45 am

2 stops16h 43m

Cusco Velazco Astete

mar. 12/9

5:00 am-9:13 am

2 stops29h 13m

$1,034

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

sáb. 12/6

6:00 am-12:45 am

2 stops17h 45m

Cusco Velazco Astete

lun. 12/8

7:50 pm-12:47 pm

2 stops17h 57m

$1,034

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

sáb. 10/11

7:10 am-12:35 am

2 stops17h 25m

Cusco Velazco Astete

lun. 10/13

7:00 pm-10:19 am

2 stops15h 19m

$2,494

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

sáb. 12/6

3:20 pm-10:26 am

3 stops18h 06m

Cusco Velazco Astete

lun. 12/8

8:57 pm-2:47 pm

3 stops18h 50m

$2,884

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Cusco?

    There are many flights that can get you from Panama City, Florida to Cusco in 16h 43m. Fly via Delta or American Airlines to get the fastest option. The distance between Panama City, Florida and Cusco is about 3168 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

    Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.

  • Can I find deals for business class flights from Panama City to Cuzco?

    Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Cusco?

    Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Cusco (average of $789). Flying from Panama City, Florida to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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