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$1,120+ Cheap flights from Panama City, FL (ECP) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CUZ
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Panama City to Cuzco

Cheapest flights from Panama City to Cuzco
Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:00 pmECP - CUZ
2 stops17h 40mDelta
Tue 12/97:35 amCUZ - ECP
2 stops16h 02mDelta
Deal found 10/27$1,120

Cheap flight deals from Panama City to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$1,120
(Delta)
Provider with most accurate pricing for Panama City NW Florida Beaches-Cusco Velazco Astete flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Cusco Velazco Astete flights.
Search Deals
From Panama City NW Florida Beaches to Cusco Velazco Astete
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Panama City

Fly to

Cuzco

Route

Depart

Return

Price

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Sat 12/6

1:32 pm-11:10 am

2 stops20h 38m

Cusco Velazco Astete

Tue 12/9

7:50 pm-12:47 pm

2 stops17h 57m

$1,120

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

  • Most accurate provider: When it comes to deals on Panama City, Florida-Cusco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Cusco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Cusco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Cusco?

    There are many flights that can get you from Panama City, Florida to Cusco in 20h 38m. Fly via Delta to get the fastest option. The distance between Panama City, Florida and Cusco is about 3168 mi.

  • Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

    Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.

  • Can I find deals for business class flights from Panama City to Cuzco?

    Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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