What is the cheapest month to book a flight from Panama City, Florida to Cusco?

Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Cusco (average of $789). Flying from Panama City, Florida to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

In terms of precipitation, rainfall in Cusco ranges from 0.0 - 5.5 inches per month. January is typically the wettest month, when rainfall can reach 5.5 in. May is typically the driest time to visit Cusco when rainfall is around 0.0 in.

If weather is an important factor for your trip to Cusco, use this chart to help with planning. For those seeking warmer temperatures, October is the ideal time of year to visit, when temperatures reach an average of 55.4 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 50.0 F).

What is the cheapest time of day to fly from ECP to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Cusco as you normally would.

Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Cuzco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.

Can I find deals for business class flights from Panama City to Cuzco?

Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$944+ Flights from Panama City, FL to Cusco

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Cheap flight deals from Panama City to Cuzco

Round-trip from	$944 (Delta)

From Panama City NW Florida Beaches to Cusco Velazco Astete

Search Deals

Find flight deals from Panama City to Cuzco

Cheapest flights from Panama City to Cuzco
Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Sat 12/62:00 pmECP - CUZ

2 stops44h 40mDelta

Tue 12/99:30 pmCUZ - ECP

2 stops26h 13mDelta

Deal found 7/28

$944

Sat 9/2011:56 amECP - CUZ

3 stops19h 28mAmerican Airlines

Fri 10/34:52 pmCUZ - ECP

3 stops21h 27mAmerican Airlines

Deal found 7/26

$2,860

Best flights from Panama City to Cuzco
Discover carefully curated flight deals from Panama City to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2025.

Sat 12/62:00 pmECP - CUZ

2 stops44h 40mDelta

Tue 12/99:30 pmCUZ - ECP

2 stops26h 13mDelta

Deal found 7/28

$944

Sat 9/2011:56 amECP - CUZ

3 stops19h 28mAmerican Airlines

Fri 10/34:52 pmCUZ - ECP

3 stops21h 27mAmerican Airlines

Deal found 7/26

$2,860

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Sat 12/6

2:00 pm-11:40 am

2 stops44h 40m

Cusco Velazco Astete

Tue 12/9

9:30 pm-10:43 pm

2 stops26h 13m

$944

Panama CityCusco

ECP - CUZ

ECPCUZ

Panama City NW Florida Beaches

Sat 9/20

11:56 am-7:24 am

3 stops19h 28m

Cusco Velazco Astete

Fri 10/3

4:52 pm-2:19 pm

3 stops21h 27m

$2,860

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Cuzco

See what other customers who have flown with Delta and American Airlines from Panama City to Cusco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Delta

8.0

Very good

7,979 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,979 reviews

Reviews

1 / 20

6.0

Good

pilar,May 2025

RSW - ATL

Related info for your journey

Can I find deals for flights from Panama City to Cuzco that include hotel bookings?
Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Cuzco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.
Can I find deals for business class flights from Panama City to Cuzco?
Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to Cusco?
Currently, February is the cheapest month in which you can book a flight from Panama City, Florida to Cusco (average of $789). Flying from Panama City, Florida to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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$944+ Cheap flights from Panama City, FL (ECP) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Cuzco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to Cuzco

Round-trip from

Find flight deals from Panama City to Cuzco

Cheapest flights from Panama City to CuzcoExplore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated July 29, 2025.

See what other customers who have flown with Delta and American Airlines from Panama City to Cusco have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

How can I find direct flights from Panama City to Cuzco?

Can I find deals for business class flights from Panama City to Cuzco?

What is the cheapest month to book a flight from Panama City, Florida to Cusco?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.

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Travel Smart

Cheapest flights from Panama City to Cuzco
Explore the most affordable flight options available from Panama City to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.