$283+ Cheap flights from Panama to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Jun 14 — Jun 211
Round-trip
1 adult, Economy
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Find cheap flights from Panama to Chicago with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama to ChicagoExplore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Tue 7/141:50 pm
ORD
- PTY
2 stops18h 16m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$663
This Avianca deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Sun 5/2411:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 5/12![Avianca logo]()
$684
This Avianca deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Wed 5/2711:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 5/13![Avianca logo]()
$687
This Avianca deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Sat 6/275:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 5/10![Avianca logo]()
$688
This flugladen.de deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:55 pm
PTY
- ORD
1 stop27h 25m
Avianca
Sun 6/711:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 5/10![Avianca logo]()
$697
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:10 am
PTY
- ORD
2 stops26h 14m
Multiple Airlines
Thu 6/116:55 am
ORD
- PTY
1 stop13h 39m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$700
This Vliegwinkel deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Vliegwinkel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Thu 7/95:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 5/12![Avianca logo]()
$703
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Fri 8/71:50 pm
ORD
- PTY
2 stops18h 40m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$705
This Avianca deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Tue 6/911:20 pm
ORD
- PTY
1 stop14h 55m
Avianca
Deal found 5/12![Avianca logo]()
$706
This Gotogate deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:10 pm
PTY
- ORD
1 stop30h 10m
Avianca
Thu 6/45:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 5/10![Avianca logo]()
$707
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/132:20 pm
PTY
- MDW
1 stop8h 16m
Delta
Tue 8/186:05 am
MDW
- PTY
1 stop6h 50m
Delta
Deal found 5/13![Delta logo]()
$719
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Sat 8/156:05 am
MDW
- PTY
1 stop7h 00m
Delta
Deal found 5/12![Delta logo]()
$721
Best flights from Panama to ChicagoDiscover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
Discover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 15, 2026.
This Copa Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Fri 9/183:20 pm
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Deal found 5/10![Copa Airlines logo]()
$713
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:21 pm
PTY
- ORD
2 stops17h 35m
Delta
Fri 9/185:30 am
ORD
- PTY
1 stop7h 26m
Delta
Deal found 5/14![Delta logo]()
$719
This United Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/153:30 pm
PTY
- ORD
1 stop9h 15m
United Airlines
Mon 7/209:40 pm
ORD
- PTY
1 stop16h 34m
United Airlines
Deal found 5/13![United Airlines logo]()
$721
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:15 pm
PTY
- MDW
2 stops20h 12m
Multiple Airlines
Sat 8/156:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$742
This Copa Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:40 pm
PTY
- ORD
Nonstop5h 44m
Copa Airlines
Wed 11/47:35 am
ORD
- PTY
Nonstop5h 25m
Copa Airlines
Deal found 5/11![Copa Airlines logo]()
$713
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:20 pm
PTY
- MDW
1 stop8h 16m
Delta
Wed 8/196:05 am
MDW
- PTY
1 stop6h 50m
Delta
Deal found 5/11![Delta logo]()
$721
This Copa Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Sat 8/153:21 pm
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Deal found 5/12![Copa Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/12:27 pm
PTY
- MDW
1 stop7h 48m
Delta
Sat 8/86:05 am
MDW
- PTY
1 stop7h 00m
Delta
Deal found 5/10![Delta logo]()
$721
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/210:26 am
PTY
- MDW
1 stop11h 36m
Multiple Airlines
Tue 6/96:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$812
This Copa Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1510:10 pm
PTY
- ORD
Nonstop5h 50m
Copa Airlines
Mon 7/208:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Deal found 5/13![Copa Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Sat 8/156:05 am
MDW
- PTY
1 stop7h 00m
Delta
Deal found 5/12![Delta logo]()
$721
This Copa Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:10 am
PTY
- ORD
Nonstop5h 47m
Copa Airlines
Tue 8/118:02 am
ORD
- PTY
Nonstop5h 20m
Copa Airlines
Deal found 5/12![Copa Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Fri 6/126:00 am
MDW
- PTY
1 stop7h 09m
Delta
Deal found 5/10![Delta logo]()
$752
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:15 pm
PTY
- MDW
2 stops18h 28m
Delta
Mon 6/296:00 am
MDW
- PTY
1 stop7h 09m
Delta
Deal found 5/10![Delta logo]()
$829
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/92:24 pm
PTY
- MDW
1 stop7h 51m
Delta
Wed 7/156:00 am
MDW
- PTY
1 stop7h 05m
Delta
Deal found 5/13![Delta logo]()
$858
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/282:24 pm
PTY
- MDW
1 stop7h 51m
Delta
Tue 8/116:05 am
MDW
- PTY
1 stop6h 50m
Delta
Deal found 5/12![Delta logo]()
$858
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:24 pm
PTY
- MDW
1 stop7h 51m
Delta
Tue 7/286:00 am
MDW
- PTY
1 stop7h 05m
Delta
Deal found 5/14![Delta logo]()
$858
Last-minute flights from Panama to ChicagoDiscover last-minute flight deals from Panama to Chicago. Data last updated May 15, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Chicago. Data last updated May 15, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Sun 5/2411:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 5/12![Avianca logo]()
$684
This Avianca deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/204:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Wed 5/2711:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 5/13![Avianca logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/254:25 am
PTY
- MDW
2 stops33h 47m
Multiple Airlines
Tue 6/96:00 am
MDW
- PTY
1 stop14h 34m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$803
This flugladen.de deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure flugladen.de is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:55 pm
PTY
- ORD
1 stop27h 25m
Avianca
Sun 6/711:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 5/10![Avianca logo]()
$697
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:10 am
PTY
- ORD
2 stops26h 14m
Multiple Airlines
Thu 6/116:55 am
ORD
- PTY
1 stop13h 39m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$700
This Avianca deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Tue 6/911:20 pm
ORD
- PTY
1 stop14h 55m
Avianca
Deal found 5/12![Avianca logo]()
$706
This Gotogate deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:10 pm
PTY
- ORD
1 stop30h 10m
Avianca
Thu 6/45:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 5/10![Avianca logo]()
$707
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/29:33 pm
PTY
- MDW
2 stops24h 29m
Multiple Airlines
Tue 6/912:27 pm
MDW
- PTY
1 stop8h 07m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$786
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Fri 8/71:50 pm
ORD
- PTY
2 stops18h 40m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$705
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:24 pm
PTY
- MDW
1 stop7h 53m
Delta
Fri 6/126:00 am
MDW
- PTY
1 stop7h 09m
Delta
Deal found 5/10![Delta logo]()
$752
This Avianca deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1210:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Sat 6/275:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 5/10![Avianca logo]()
$688
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Tue 7/141:50 pm
ORD
- PTY
2 stops18h 16m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$663
One-way flights from Panama to ChicagoSearch for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
Search for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated May 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:25 am
PTY
- MDW
3 stops17h 46m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:55 pm
PTY
- ORD
3 stops25h 46m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:25 am
PTY
- ORD
3 stops27h 38m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$299
This FlipMilhas deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlipMilhas is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/2110:10 am
PTY
- ORD
1 stop11h 10m
GOL
Deal found 5/10![GOL logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/219:48 pm
PTY
- ORD
2 stops22h 05m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/23:10 pm
PTY
- MDW
3 stops43h 57m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$323
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/114:25 am
PTY
- MDW
3 stops17h 46m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:10 pm
PTY
- ORD
3 stops40h 43m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/410:10 am
PTY
- ORD
3 stops43h 18m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/115:55 pm
PTY
- ORD
3 stops25h 55m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$347
This Super.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2110:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 5/11![Avianca logo]()
$370
This Avianca deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/194:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 5/12![Avianca logo]()
$372
Find flight deals from Panama to Chicago
Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated May 15, 2026.
Round-trip from | $658 (Kiwi.com) |
|---|---|
One-way from | $283 (Kiwi.com) |
Popular in | May |
Cheapest in | July |
Average price | $741 |
Good round-trip deal | $781 or less |
Good one-way deal | $784 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Mon 9/14
7:25 pm-1:02 am
Nonstop5h 37m
Chicago O'Hare Intl
Fri 9/18
3:20 pm-8:41 pm
Nonstop5h 21m
$713
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Sat 10/31
7:40 pm-1:24 am
Nonstop5h 44m
Chicago O'Hare Intl
Wed 11/4
7:35 am-2:00 pm
Nonstop5h 25m
$713
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Wed 7/1
10:10 pm-4:00 am
Nonstop5h 50m
Chicago O'Hare Intl
Sat 8/15
3:21 pm-8:41 pm
Nonstop5h 20m
$715
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Wed 7/15
10:10 pm-4:00 am
Nonstop5h 50m
Chicago O'Hare Intl
Mon 7/20
8:02 am-1:22 pm
Nonstop5h 20m
$715
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 7/28
8:10 am-1:57 pm
Nonstop5h 47m
Chicago O'Hare Intl
Tue 8/11
8:02 am-1:22 pm
Nonstop5h 20m
$715
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Mon 9/14
2:21 pm-7:56 am
2 stops17h 35m
Chicago O'Hare Intl
Fri 9/18
5:30 am-12:56 pm
1 stop7h 26m
$719
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Wed 7/15
3:30 pm-12:45 am
1 stop9h 15m
Chicago O'Hare Intl
Mon 7/20
9:40 pm-2:14 pm
1 stop16h 34m
$721
Panama CityChicago
PTY - MDW
PTYMDW
Panama City Tocumen Intl
Thu 8/6
2:20 pm-10:36 pm
1 stop8h 16m
Chicago Midway
Wed 8/19
6:05 am-12:55 pm
1 stop6h 50m
$721
Panama CityChicago
PTY - MDW
PTYMDW
Panama City Tocumen Intl
Sat 8/1
2:27 pm-10:15 pm
1 stop7h 48m
Chicago Midway
Sat 8/8
6:05 am-1:05 pm
1 stop7h 00m
$721
Panama CityChicago
PTY - MDW
PTYMDW
Panama City Tocumen Intl
Wed 7/1
2:24 pm-10:17 pm
1 stop7h 53m
Chicago Midway
Sat 8/15
6:05 am-1:05 pm
1 stop7h 00m
$721
Showing 1-10 of 46 resultsSorted by cheapest first
Best time to book a flight from Panama to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
PTY-ORD
PTY-MDW
PAC-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Chicago
PA0-CHI
PTY-ORD
PTY-MDW
PAC-ORD
How far ahead should I book a flight from Panama to Chicago?
The price you pay for your flight from Panama to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Panama to Chicago?
Currently, May is the cheapest month in which you can book a flight from Panama to Chicago (average of $201). Flying from Panama to Chicago in June is currently the most expensive (average of $418). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to CHI?
Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 15, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.
Weekly flight availability from Panama to Chicago
Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 15, 2026.
The most flights from PA0 to CHI are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated May 15, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.8
Overall
7.5
Crew
8.1
Entertainment
6.8
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Food
6.8
Overall
7.5
Crew
8.1
Entertainment
6.8
Boarding
7.8
Comfort
7.4
Reviews
1 / 20
2.0
MediocreJuan,Dec 2025
EZE - PTY
Related info for your journey
Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Lansing
Merrillville
Hammond
Porter
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes
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Alternative routes for Panama to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 15, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Chicago by cabin class
Find flights from Panama to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Chicago flights
Browse other Panama and Chicago flight options. Last updated on May 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Chicago
Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$405 | Average$671 | FlexibilityNo cancel fee | On-time70% |