$367+ Cheap flights from Panama to Chicago (CHI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Nov 16 — Nov 231
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Panama to Chicago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama to Chicago
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama to ChicagoExplore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2026.
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 17, 2026.
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:33 pm -
1 stop24h 06m
Tue 1/56:59 am -
1 stop7h 34m
Deal found 10/14![American Airlines logo]()
$752
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:20 pm -
Nonstop5h 37m
Thu 11/52:13 pm -
Nonstop5h 24m
Deal found 10/13![Copa Airlines logo]()
$757
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/274:33 pm -
1 stop16h 10m
Thu 1/77:00 am -
1 stop7h 55m
Deal found 10/12![American Airlines logo]()
$760
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:31 pm -
2 stops36h 29m
Fri 1/812:04 am -
1 stop12h 29m
Deal found 10/13![Multiple Airlines logo]()
$761
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:31 pm -
2 stops21h 59m
Fri 1/812:04 am -
1 stop12h 29m
Deal found 10/13![Multiple Airlines logo]()
$762
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/313:41 pm -
1 stop18h 29m
Sat 11/79:25 am -
1 stop9h 13m
Deal found 10/13![United Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:02 pm -
1 stop17h 45m
Thu 11/57:50 pm -
1 stop17h 23m
Deal found 10/13![American Airlines logo]()
$768
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:13 pm -
1 stop9h 43m
Wed 11/186:00 am -
1 stop7h 13m
Deal found 10/14![American Airlines logo]()
$769
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:31 pm -
2 stops21h 59m
Wed 1/61:05 am -
1 stop11h 28m
Deal found 10/13![Multiple Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:13 pm -
2 stops17h 14m
Fri 11/67:50 pm -
1 stop17h 23m
Deal found 10/12![American Airlines logo]()
$776
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/217:35 am -
1 stop10h 23m
Deal found 10/15![Copa Airlines logo]()
$1,378
Best flights from Panama to ChicagoDiscover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 17, 2026.
Discover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 17, 2026.
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:28 pm -
Nonstop5h 43m
Sat 11/72:13 pm -
Nonstop5h 24m
Deal found 10/15![Copa Airlines logo]()
$757
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:24 pm -
1 stop9h 33m
Sat 11/75:27 am -
1 stop7h 32m
Deal found 10/17![Delta logo]()
$763
This United Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:00 am -
1 stop15h 01m
Thu 11/196:55 am -
1 stop11h 43m
Deal found 10/13![United Airlines logo]()
$763
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/234:33 pm -
1 stop24h 06m
Fri 1/15:59 pm -
1 stop18h 42m
Deal found 10/12![American Airlines logo]()
$783
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:28 pm -
Nonstop5h 43m
Mon 11/307:35 am -
Nonstop5h 26m
Deal found 10/13![Copa Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/234:41 pm -
1 stop17h 30m
Thu 12/106:50 am -
1 stop11h 48m
Deal found 10/12![United Airlines logo]()
$763
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:05 am -
Nonstop5h 41m
Tue 11/102:13 pm -
Nonstop5h 24m
Deal found 10/13![Copa Airlines logo]()
$757
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/310:00 am -
1 stop25h 48m
Thu 11/59:35 pm -
1 stop16h 10m
Deal found 10/15![United Airlines logo]()
$784
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:28 pm -
Nonstop5h 43m
Sun 11/297:35 am -
Nonstop5h 26m
Deal found 10/13![Copa Airlines logo]()
$779
This Copa Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/217:35 am -
1 stop10h 23m
Deal found 10/15![Copa Airlines logo]()
$1,378
Last-minute flights from Panama to ChicagoDiscover last-minute flight deals from Panama to Chicago. Data last updated October 17, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Chicago. Data last updated October 17, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/202:02 pm -
2 stops17h 25m
Fri 10/238:55 pm -
2 stops16h 07m
Deal found 10/12![American Airlines logo]()
$777
This Copa Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:20 pm -
Nonstop5h 37m
Thu 11/52:13 pm -
Nonstop5h 24m
Deal found 10/13![Copa Airlines logo]()
$757
This American Airlines deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:02 pm -
1 stop17h 45m
Thu 11/57:50 pm -
1 stop17h 23m
Deal found 10/13![American Airlines logo]()
$768
This Delta deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:24 pm -
1 stop9h 33m
Sat 11/75:27 am -
1 stop7h 32m
Deal found 10/17![Delta logo]()
$763
This Copa Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:28 pm -
Nonstop5h 43m
Sat 11/77:35 am -
Nonstop5h 26m
Deal found 10/16![Copa Airlines logo]()
$779
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:31 pm -
2 stops21h 59m
Fri 1/812:04 am -
1 stop12h 29m
Deal found 10/13![Multiple Airlines logo]()
$762
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/29:31 pm -
2 stops21h 59m
Wed 1/61:05 am -
1 stop11h 28m
Deal found 10/13![Multiple Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/23:13 pm -
2 stops17h 14m
Fri 11/67:50 pm -
1 stop17h 23m
Deal found 10/12![American Airlines logo]()
$776
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/39:31 pm -
2 stops36h 29m
Fri 1/812:04 am -
1 stop12h 29m
Deal found 10/13![Multiple Airlines logo]()
$761
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/123:13 pm -
1 stop9h 43m
Wed 11/186:00 am -
1 stop7h 13m
Deal found 10/14![American Airlines logo]()
$769
One-way flights from Panama to ChicagoSearch for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated October 17, 2026.
Search for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated October 17, 2026.
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/252:47 pm -
1 stop10h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/12![American Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:15 pm -
2 stops19h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:00 pm -
2 stops27h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$391
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/159:31 pm -
2 stops45h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:00 pm -
2 stops18h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 10/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1212:33 pm -
2 stops21h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/13![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:15 pm -
2 stops30h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$409
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:31 pm -
2 stops36h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$418
Find flight deals from Panama to Chicago
Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated October 17, 2026.
Round-trip from | $707 (American Airlines) |
|---|---|
One-way from | $367 (American Airlines) |
Popular in | July |
Cheapest in | April |
Average price | $743 |
Good round-trip deal | $736 or less |
Good one-way deal | $629 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 17, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Thu 2/25
4:31 pm-7:25 am
2 stops15h 54m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$377
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Tue 11/10
6:15 pm-5:07 pm
3 stops23h 52m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$428
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 11/16
12:56 pm-12:21 am
1 stop12h 25m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$485
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sun 11/15
9:31 pm-4:43 am
1 stop32h 12m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$494
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Tue 11/24
3:34 pm-7:32 am
2 stops16h 58m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$588
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Fri 10/30
9:31 pm-4:37 pm
3 stops43h 06m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$596
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 1/4
1:22 pm-11:44 pm
3 stops35h 22m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$640
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 1/4
4:33 pm-8:20 am
2 stops16h 47m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$679
Quickest round-trip
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 11/16
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$727
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sun 11/15
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$727
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Panama to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
PTY-ORD
DAV-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Chicago
PA0-CHI
PTY-ORD
DAV-ORD
What is the cheapest month to book a flight from Panama to Chicago?
Currently, April is the cheapest month in which you can book a flight from Panama to Chicago (average of $586). Flying from Panama to Chicago in March is currently the most expensive (average of $808). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to CHI?
Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 17, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.
Weekly flight availability from Panama to Chicago
Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated October 17, 2026.
The most flights from PA0 to CHI are scheduled on a Monday (5 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated October 17, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Entertainment
6.9
Overall
7.6
Food
6.9
Comfort
7.4
Crew
8.1
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Merrillville
Lansing
Valparaiso
Hammond
Saint Joseph
Porter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Chicago flight routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for Panama to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 17, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Chicago by cabin class
Find flights from Panama to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Chicago flights
Browse other Panama and Chicago flight options. Last updated on October 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Chicago
Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$574 | Average$801 | FlexibilityNo cancel fee | On-time70% |