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$308+ Cheap flights from Panama to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Jun 29 — Jul 61
Mon 6/29
Mon 7/6
1 adult, Economy
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Cheap flight deals from Panama to Chicago

Cheapest flights from Panama to Chicago
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 30, 2026.

This Mytrip deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:55 pm
PTY
-
ORD
3 stops35h 57m
Multiple Airlines
Mon 9/141:40 am
ORD
-
PTY
3 stops24h 15m
Multiple Airlines
Deal found 5/29$652
This Mytrip deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:10 pm
PTY
-
ORD
1 stop30h 10m
Multiple Airlines
Tue 9/291:40 am
ORD
-
PTY
3 stops22h 55m
Multiple Airlines
Deal found 5/27$681
This Avianca deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
Wed 7/1511:20 pm
ORD
-
PTY
1 stop17h 40m
Avianca
Deal found 5/28$682
This Avianca deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
Sat 6/2711:20 pm
ORD
-
PTY
1 stop17h 40m
Avianca
Deal found 5/29$687
This Avianca deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/44:25 am
PTY
-
ORD
1 stop16h 55m
Avianca
Thu 6/115:15 pm
ORD
-
PTY
1 stop8h 40m
Avianca
Deal found 5/28$688
This Mytrip deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:55 pm
PTY
-
ORD
1 stop27h 25m
Multiple Airlines
Sun 8/92:53 am
ORD
-
PTY
3 stops35h 22m
Multiple Airlines
Deal found 5/28$689
This Mytrip deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:10 pm
PTY
-
ORD
1 stop30h 10m
Multiple Airlines
Thu 9/171:40 am
ORD
-
PTY
3 stops24h 15m
Multiple Airlines
Deal found 5/29$692
This SmartFares deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:55 pm
PTY
-
ORD
1 stop27h 25m
Avianca
Wed 7/811:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Deal found 5/28$699
This Mytrip deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:55 pm
PTY
-
ORD
3 stops35h 57m
Multiple Airlines
Thu 9/101:40 am
ORD
-
PTY
3 stops22h 55m
Multiple Airlines
Deal found 5/26$705
This Avianca deal was found by Cheapflights users on 5/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:25 am
PTY
-
ORD
1 stop16h 55m
Avianca
Mon 7/1311:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Deal found 5/29$708
This Delta deal was found by Cheapflights users on 5/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:21 pm
PTY
-
MDW
1 stop8h 04m
Delta
Fri 9/186:05 am
MDW
-
PTY
1 stop6h 51m
Delta
Deal found 5/28$740
This Delta deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/162:24 pm
PTY
-
MDW
1 stop7h 51m
Delta
Wed 7/226:00 am
MDW
-
PTY
1 stop7h 05m
Delta
Deal found 5/27$742

Find flight deals from Panama to Chicago

Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated May 30, 2026.

Round-trip from

$652
(Mytrip)

One-way from

$308
(Kiwi.com)

Popular in

May

Cheapest in

July

Average price

$741

Good round-trip deal

$801 or less

Good one-way deal

$753 or less
From Panama to Chicago (CHI)
Search Deals
One-way flight from Panama to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals
Price to beat on a round-trip flight from Panama to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Panama to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 30, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 7/16

10:10 am-9:20 pm

1 stop11h 10m

Chicago O'Hare Intl

Wed 7/22

11:20 pm-9:15 am

1 stop9h 55m

$686

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 9/14

8:10 am-1:59 pm

Nonstop5h 49m

Chicago O'Hare Intl

Fri 9/18

8:01 am-1:22 pm

Nonstop5h 21m

$735

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 8/19

8:10 am-1:59 pm

Nonstop5h 49m

Chicago O'Hare Intl

Sun 8/23

3:21 pm-8:41 pm

Nonstop5h 20m

$737

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 7/15

10:10 pm-4:00 am

Nonstop5h 50m

Chicago O'Hare Intl

Mon 7/20

8:02 am-1:22 pm

Nonstop5h 20m

$737

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 7/16

8:10 am-1:57 pm

Nonstop5h 47m

Chicago O'Hare Intl

Wed 7/22

8:02 am-1:22 pm

Nonstop5h 20m

$737
Quickest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 8/17

7:25 pm-1:02 am

Nonstop5h 37m

Chicago O'Hare Intl

Tue 9/8

8:01 am-1:22 pm

Nonstop5h 21m

$737

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Mon 9/14

2:21 pm-10:25 pm

1 stop8h 04m

Chicago Midway

Fri 9/18

6:05 am-12:56 pm

1 stop6h 51m

$740

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/9

3:30 pm-12:23 am

1 stop8h 53m

Chicago O'Hare Intl

Thu 10/15

6:25 am-2:14 pm

1 stop7h 49m

$740

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 8/4

2:20 pm-10:36 pm

1 stop8h 16m

Chicago Midway

Sat 8/8

6:05 am-1:05 pm

1 stop7h 00m

$742

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 7/16

2:24 pm-10:15 pm

1 stop7h 51m

Chicago Midway

Wed 7/22

6:00 am-1:05 pm

1 stop7h 05m

$742

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/27

Showing 1-10 of 43 resultsSorted by cheapest first
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Best time to book a flight from Panama to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Chicago

What is the cheapest month to book a flight from Panama to Chicago?

Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in June is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CHI?

Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 30, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.

How far ahead should I book a flight from Panama to Chicago?

The price you pay for your flight from Panama to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 50 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated May 30, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,574 reviews

Entertainment

6.8

Food

6.9

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.
Copa Airlines
7.5
Good
1,574 reviews
Copa Airlines
7.5
Good
1,574 reviews

Entertainment

6.8

Food

6.9

Comfort

7.4

Crew

8.1

Boarding

7.8

Overall

7.5

Reviews

1 / 20
2.0
Mediocre

Juan,Dec 2025

EZE - PTY

The outbound flight from Boston was awful. The handicapped services were the worst i have ever seen. NEVER AGAIN. THIS WAS NOT WORTH ANYWHERE NEAR $4K.

Related info for your journey

Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Chicago?

    There are many flights that can get you from Panama to Chicago in 5h 49m. Fly via Avianca, Copa Airlines, or Delta to get the fastest option. Panama and Chicago are separated by a distance of 2330 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Panama to Chicago?

    The most popular flight routes from Panama to Chicago are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Marcos A. Gelabert Intl - Chicago O'Hare Intl.

  • What are the most reliable airlines from Panama to Chicago?

    No one likes to see their flight delayed. When booking a flight from Panama to Chicago consider choosing Copa Airlines (90%), United Airlines (85%) or EVA Air (85%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama to Chicago?

    The cheapest flight price from Panama to Chicago is $683. On average you can expect to pay $1,019. The most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl), can usually be booked for $686.

  • Can I find deals for flights from Panama to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Chicago.

  • Can I find deals for business class flights from Panama to Chicago?

    Yes. Cheapflights offers flight deals from Panama to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Chicago?

    Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in June is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Benton Harbor
Lansing
Merrillville
Hammond
Porter

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama to Chicago

Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$405Average$702FlexibilityNo cancel feeOn-time70%

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