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$283+ Cheap flights from Panama to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Panama to Chicago

Cheapest flights from Panama to Chicago
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:55 amPTY - ORD
1 stop18h 25mAvianca
Tue 12/304:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/16$561
This Cheapflightsfares deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:45 amPTY - ORD
1 stop11h 35mAvianca
Wed 1/1410:20 pmORD - PTY
1 stop14h 40mAvianca
Deal found 12/16$590
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:25 amPTY - ORD
1 stop9h 35mMultiple Airlines
Mon 1/55:00 amORD - PTY
2 stops28h 30mMultiple Airlines
Deal found 12/15$596
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:55 amPTY - ORD
1 stop18h 25mAvianca
Tue 12/304:10 pmORD - PTY
1 stop17h 20mAvianca
Deal found 12/17$601
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/239:45 amPTY - ORD
1 stop11h 35mAvianca
Fri 1/210:20 pmORD - PTY
1 stop9h 30mAvianca
Deal found 12/17$611
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/272:55 amPTY - ORD
1 stop18h 25mAvianca
Fri 1/910:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 12/17$651
This Cheapflightsfares deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:55 amPTY - ORD
1 stop18h 25mAvianca
Sun 1/410:20 pmORD - PTY
1 stop17h 35mAvianca
Deal found 12/17$661
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3011:55 pmPTY - ORD
1 stop10h 59mUnited Airlines
Thu 1/299:05 pmORD - PTY
1 stop16h 40mUnited Airlines
Deal found 12/16$665
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/259:25 amPTY - MDW
1 stop9h 13mMultiple Airlines
Mon 1/56:15 amMDW - PTY
1 stop9h 56mMultiple Airlines
Deal found 12/15$804
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:22 pmPTY - MDW
1 stop8h 00mDelta
Fri 1/26:00 amMDW - PTY
1 stop6h 57mDelta
Deal found 12/16$959
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:22 pmPTY - MDW
1 stop8h 00mDelta
Sun 1/46:00 amMDW - PTY
1 stop13h 00mDelta
Deal found 12/17$1,076
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:00 amPTY - MDW
1 stop9h 20mDelta
Thu 1/296:00 amMDW - PTY
1 stop6h 55mDelta
Deal found 12/15$1,156

Find flight deals from Panama to Chicago

Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated December 18, 2025.

Round-trip from

$393
(Kiwi.com)

One-way from

$283
(Kiwi.com)

Popular in

December

Cheapest in

July

Average price

$581

Good round-trip deal

$597 or less

Good one-way deal

$565 or less
From Panama to Chicago (CHI)
Search Deals
One-way flight from Panama to Chicago (CHI)
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High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Panama to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Panama to Chicago (CHI).
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.

Fly from

Panama

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/30

9:33 pm-8:18 am

1 stop11h 45m

Chicago O'Hare Intl

Fri 2/6

6:57 pm-8:06 am

1 stop12h 09m

$397

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/16

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Tue 1/20

10:20 pm-4:55 pm

1 stop17h 35m

$555

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 1/14

9:45 am-8:20 pm

1 stop11h 35m

Chicago O'Hare Intl

Sun 1/25

10:20 pm-2:00 pm

1 stop14h 40m

$555

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 1/16

2:55 am-8:20 pm

1 stop18h 25m

Chicago O'Hare Intl

Wed 1/21

10:20 pm-4:55 pm

1 stop17h 35m

$555

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 2/1

7:50 pm-11:47 pm

3 stops28h 57m

Chicago O'Hare Intl

Sun 2/8

5:15 am-2:00 pm

3 stops31h 45m

$571

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sat 5/2

5:25 pm-1:15 pm

1 stop19h 50m

Chicago O'Hare Intl

Sun 5/10

2:35 pm-12:10 am

1 stop9h 35m

$579

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 5/12

8:10 am-2:06 pm

Nonstop5h 56m

Chicago O'Hare Intl

Tue 5/26

3:21 pm-8:41 pm

Nonstop5h 20m

$580

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 4/2

8:10 am-1:58 pm

Nonstop5h 48m

Chicago O'Hare Intl

Sun 4/5

3:21 pm-8:41 pm

Nonstop5h 20m

$580

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 3/15

7:20 pm-1:04 am

Nonstop5h 44m

Chicago O'Hare Intl

Tue 3/31

3:28 pm-8:41 pm

Nonstop5h 13m

$582

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 4/2

10:55 pm-9:14 am

1 stop10h 19m

Chicago O'Hare Intl

Sun 4/5

7:35 am-6:37 pm

1 stop11h 02m

$585

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 35 results
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Best time to book a flight from Panama to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Chicago

What is the cheapest month to book a flight from Panama to Chicago?

Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in April is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CHI?

Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 19% on flights from Panama to Chicago by exploring options for tickets in the afternoon.

Weekly flight availability from Panama to Chicago

Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 18, 2025.

The most flights from PA0 to CHI are scheduled on a Monday (5 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,556 reviews
Copa Airlines
7.6
Good
1,556 reviews

Entertainment

6.8

Food

6.8

Boarding

7.8

Comfort

7.4

Crew

8.1

Overall

7.6

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Chicago?

    There are many flights that can get you from Panama to Chicago in 7h 47m. Fly via Avianca or Delta to get the fastest option. Panama and Chicago are separated by a distance of 2316 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Panama to Chicago one-way?

    To fly one-way, consider booking your trip with Avianca, which is currently one of the cheapest options available, starting at $234. Copa Airlines flights start at $255 while deals on United Airlines start at $444 one-way.

  • What are the most popular routes from Panama to Chicago?

    The most popular flight routes from Panama to Chicago are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Marcos A. Gelabert Intl - Chicago O'Hare Intl.

  • What are the most reliable airlines from Panama to Chicago?

    No one likes to see their flight delayed. When booking a flight from Panama to Chicago consider choosing EVA Air (93%), Copa Airlines (90%) or United Airlines (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama to Chicago?

    The cheapest flight price from Panama to Chicago is $392. On average you can expect to pay $634. The most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl), can usually be booked for $393.

  • Can I find deals for flights from Panama to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Chicago.

  • Can I find deals for business class flights from Panama to Chicago?

    Yes. Cheapflights offers flight deals from Panama to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Chicago?

    Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in April is currently the most expensive (average of $484). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lansing
Merrillville
Hammond
Porter
Benton Harbor

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
San José to O'Hare Intl flights
Guatemala City to O'Hare Intl flights
Panama City to O'Hare Intl flights
San José to Midway flights
San Salvador to O'Hare Intl flights
Guatemala City to Midway flights
San Pedro Sula to O'Hare Intl flights
Philip S.W.Goldson to O'Hare Intl flights
San José to St. Louis flights
Liberia to O'Hare Intl flights
San Pedro Sula to Midway flights
Managua to O'Hare Intl flights
Philip S.W.Goldson to Midway flights
Guatemala City to St. Louis flights
San Pedro Sula to St. Louis flights
Panama City to St. Louis flights
Coxen Hole to O'Hare Intl flights
Managua to Midway flights
Tegucigalpa to St. Louis flights
Managua to St. Louis flights
Tegucigalpa to O'Hare Intl flights
Tegucigalpa to Midway flights

Top 2 airlines flying from Panama to Chicago

Discover the top 2 airlines that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$405Average$592FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$423Average$485FlexibilityNo cancel feeOn-time69%

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