$303+ Cheap flights from Panama to Chicago (CHI)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Aug 10 — Aug 171
Round-trip
1 adult, Economy
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Cheapest flights from Panama to ChicagoExplore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Fri 8/287:35 am
ORD
- PTY
1 stop10h 19m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$591
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Sat 8/221:40 am
ORD
- PTY
1 stop12h 25m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:10 am
PTY
- ORD
2 stops26h 05m
Multiple Airlines
Wed 8/197:35 am
ORD
- PTY
1 stop12h 39m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$642
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Tue 9/18:05 am
ORD
- PTY
1 stop12h 14m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$665
This Mytrip deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/15:30 am
PTY
- ORD
3 stops24h 22m
Multiple Airlines
Tue 9/81:40 am
ORD
- PTY
3 stops31h 35m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$671
This Avianca deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Wed 7/1511:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 7/6![Avianca logo]()
$684
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Mon 8/312:25 pm
ORD
- PTY
2 stops17h 41m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$685
This Avianca deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1910:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Sun 8/2311:20 pm
ORD
- PTY
1 stop14h 55m
Avianca
Deal found 7/9![Avianca logo]()
$687
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Sat 8/155:15 pm
ORD
- PTY
1 stop17h 15m
Avianca
Deal found 7/10![Avianca logo]()
$688
This Mytrip deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:55 pm
PTY
- ORD
3 stops35h 57m
Multiple Airlines
Wed 9/231:40 am
ORD
- PTY
3 stops31h 35m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$697
This Mytrip deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:30 am
PTY
- ORD
3 stops24h 22m
Multiple Airlines
Fri 9/251:40 am
ORD
- PTY
3 stops31h 35m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$700
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:39 pm
PTY
- MDW
2 stops19h 19m
Multiple Airlines
Sat 9/2612:03 pm
MDW
- PTY
1 stop8h 28m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$733
Best flights from Panama to ChicagoDiscover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
Discover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 11, 2026.
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/14:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Wed 9/911:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 7/10![Avianca logo]()
$687
This Copa Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:28 pm
PTY
- ORD
Nonstop5h 43m
Copa Airlines
Sat 11/282:13 pm
ORD
- PTY
Nonstop5h 24m
Copa Airlines
Deal found 7/7![Copa Airlines logo]()
$756
This United Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:55 am
PTY
- ORD
2 stops12h 45m
United Airlines
Thu 11/59:35 pm
ORD
- PTY
1 stop16h 10m
United Airlines
Deal found 7/6![United Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:21 pm
PTY
- MDW
1 stop8h 04m
Delta
Fri 11/66:00 am
MDW
- PTY
1 stop6h 56m
Delta
Deal found 7/11![Delta logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:57 am
PTY
- ORD
Nonstop5h 49m
Copa Airlines
Sun 11/87:35 am
ORD
- PTY
Nonstop5h 26m
Copa Airlines
Deal found 7/9![Copa Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:30 pm
PTY
- MDW
1 stop7h 40m
Delta
Sun 12/66:00 am
MDW
- PTY
1 stop7h 05m
Delta
Deal found 7/7![Delta logo]()
$762
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/93:30 pm
PTY
- ORD
1 stop18h 46m
United Airlines
Thu 10/156:29 pm
ORD
- PTY
1 stop19h 45m
United Airlines
Deal found 7/7![United Airlines logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/38:05 am
PTY
- ORD
Nonstop5h 41m
Copa Airlines
Thu 11/57:35 am
ORD
- PTY
Nonstop5h 26m
Copa Airlines
Deal found 7/8![Copa Airlines logo]()
$756
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/182:21 pm
PTY
- MDW
1 stop8h 04m
Delta
Sat 10/246:00 am
MDW
- PTY
1 stop6h 56m
Delta
Deal found 7/7![Delta logo]()
$762
This Copa Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/87:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Thu 9/248:01 am
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Deal found 7/6![Copa Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:23 pm
PTY
- MDW
1 stop8h 22m
Delta
Fri 9/186:05 am
MDW
- PTY
1 stop6h 53m
Delta
Deal found 7/10![Delta logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Wed 9/98:01 am
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Deal found 7/10![Copa Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:23 pm
PTY
- MDW
1 stop8h 22m
Delta
Wed 10/76:00 am
MDW
- PTY
1 stop6h 56m
Delta
Deal found 7/6![Delta logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Mon 9/288:01 am
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Deal found 7/9![Copa Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/12:20 pm
PTY
- MDW
1 stop8h 16m
Delta
Wed 9/96:05 am
MDW
- PTY
1 stop6h 53m
Delta
Deal found 7/10![Delta logo]()
$764
This Copa Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:25 pm
PTY
- ORD
Nonstop5h 37m
Copa Airlines
Fri 9/183:20 pm
ORD
- PTY
Nonstop5h 21m
Copa Airlines
Deal found 7/10![Copa Airlines logo]()
$758
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:23 pm
PTY
- MDW
1 stop8h 22m
Delta
Sat 9/266:05 am
MDW
- PTY
1 stop6h 53m
Delta
Deal found 7/9![Delta logo]()
$764
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/292:30 pm
PTY
- MDW
1 stop8h 06m
Delta
Tue 9/14:39 pm
MDW
- PTY
1 stop20h 16m
Delta
Deal found 7/11![Delta logo]()
$795
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:20 pm
PTY
- MDW
1 stop8h 16m
Delta
Fri 8/286:05 am
MDW
- PTY
1 stop6h 50m
Delta
Deal found 7/8![Delta logo]()
$795
Last-minute flights from Panama to ChicagoDiscover last-minute flight deals from Panama to Chicago. Data last updated July 11, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Chicago. Data last updated July 11, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2710:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Thu 7/305:15 pm
ORD
- PTY
1 stop8h 40m
Avianca
Deal found 7/8![Avianca logo]()
$709
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3110:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Mon 8/3111:20 pm
ORD
- PTY
1 stop9h 55m
Avianca
Deal found 7/10![Avianca logo]()
$708
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Sat 8/155:15 pm
ORD
- PTY
1 stop17h 15m
Avianca
Deal found 7/10![Avianca logo]()
$688
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1410:10 am
PTY
- ORD
2 stops26h 05m
Multiple Airlines
Wed 8/197:35 am
ORD
- PTY
1 stop12h 39m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$642
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/194:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Sun 8/2311:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 7/10![Avianca logo]()
$687
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Sat 8/221:40 am
ORD
- PTY
1 stop12h 25m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$594
This Avianca deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:30 am
PTY
- ORD
1 stop10h 25m
Avianca
Sun 8/2311:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 7/10![Avianca logo]()
$710
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Fri 8/287:35 am
ORD
- PTY
1 stop10h 19m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$591
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:10 am
PTY
- ORD
1 stop11h 10m
Multiple Airlines
Mon 8/312:25 pm
ORD
- PTY
2 stops17h 41m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$685
This FlightHub deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/284:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Mon 8/3111:20 pm
ORD
- PTY
1 stop17h 40m
Avianca
Deal found 7/11![Avianca logo]()
$713
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Tue 9/18:05 am
ORD
- PTY
1 stop12h 14m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$665
This Delta deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:20 pm
PTY
- MDW
1 stop25h 24m
Delta
Tue 9/14:39 pm
MDW
- PTY
1 stop20h 16m
Delta
Deal found 7/11![Delta logo]()
$764
One-way flights from Panama to ChicagoSearch for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
Search for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated July 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/155:55 pm
PTY
- ORD
3 stops18h 07m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:55 pm
PTY
- ORD
3 stops25h 58m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/114:25 am
PTY
- ORD
2 stops31h 50m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$328
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:55 pm
PTY
- MDW
3 stops41h 00m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:10 am
PTY
- ORD
2 stops13h 17m
Multiple Airlines
Deal found 7/11![Multiple Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:25 am
PTY
- ORD
2 stops19h 27m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$364
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 7/7![Avianca logo]()
$368
This Kissandfly.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:25 am
PTY
- ORD
1 stop16h 55m
Avianca
Deal found 7/8![Avianca logo]()
$371
This Avianca deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:10 am
PTY
- ORD
1 stop11h 10m
Avianca
Deal found 7/8![Avianca logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:33 pm
PTY
- MDW
2 stops25h 14m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/83:10 pm
PTY
- MDW
3 stops43h 48m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$387
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:30 am
PTY
- MDW
2 stops15h 01m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$411
Find flight deals from Panama to Chicago
Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated July 11, 2026.
Round-trip from | $591 (Kiwi.com) |
|---|---|
One-way from | $303 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $872 |
Good round-trip deal | $917 or less |
Good one-way deal | $698 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 9/1
4:25 am-9:20 pm
1 stop16h 55m
Chicago O'Hare Intl
Wed 9/9
11:20 pm-9:15 am
1 stop9h 55m
$687
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Mon 11/23
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Sat 11/28
2:13 pm-8:37 pm
Nonstop5h 24m
$756
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 11/3
8:55 am-8:40 pm
2 stops12h 45m
Chicago O'Hare Intl
Thu 11/5
9:35 pm-2:45 pm
1 stop16h 10m
$756
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Fri 10/30
7:57 am-1:46 pm
Nonstop5h 49m
Chicago O'Hare Intl
Sun 11/8
7:35 am-2:01 pm
Nonstop5h 26m
$756
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 11/3
8:05 am-12:46 pm
Nonstop5h 41m
Chicago O'Hare Intl
Thu 11/5
7:35 am-2:01 pm
Nonstop5h 26m
$756
Quickest round-trip
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 9/8
7:25 pm-1:02 am
Nonstop5h 37m
Chicago O'Hare Intl
Thu 9/24
8:01 am-1:22 pm
Nonstop5h 21m
$758
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Tue 9/1
7:25 pm-1:02 am
Nonstop5h 37m
Chicago O'Hare Intl
Wed 9/9
8:01 am-1:22 pm
Nonstop5h 21m
$758
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Fri 9/25
7:25 pm-1:02 am
Nonstop5h 37m
Chicago O'Hare Intl
Mon 9/28
8:01 am-1:22 pm
Nonstop5h 21m
$758
Panama CityChicago
PTY - ORD
PTYORD
Panama City Tocumen Intl
Mon 9/14
7:25 pm-1:02 am
Nonstop5h 37m
Chicago O'Hare Intl
Fri 9/18
3:20 pm-8:41 pm
Nonstop5h 21m
$758
Panama CityChicago
PTY - MDW
PTYMDW
Panama City Tocumen Intl
Sun 11/1
3:21 pm-10:25 pm
1 stop8h 04m
Chicago Midway
Fri 11/6
6:00 am-1:56 pm
1 stop6h 56m
$762
Showing 1-10 of 44 resultsSorted by cheapest first
Best time to book a flight from Panama to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
PTY-ORD
PTY-MDW
PAC-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Chicago
PA0-CHI
PTY-ORD
PTY-MDW
PAC-ORD
What is the cheapest month to book a flight from Panama to Chicago?
Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in June is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to CHI?
Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 11, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.
Weekly flight availability from Panama to Chicago
Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 11, 2026.
The most flights from PA0 to CHI are scheduled on a Friday (5 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).
How far ahead should I book a flight from Panama to Chicago?
The price you pay for your flight from Panama to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 51 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated July 11, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Boarding
7.8
Food
6.9
Overall
7.6
Crew
8.1
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Comfort
7.4
Boarding
7.8
Food
6.9
Overall
7.6
Crew
8.1
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Hammond
Lansing
Merrillville
Valparaiso
Porter
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes
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Complete your trip
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Alternative routes for Panama to Chicago
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 11, 2026.
Complete your trip
Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama to Chicago by cabin class
Find flights from Panama to Chicago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama and Chicago flights
Browse other Panama and Chicago flight options. Last updated on July 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Chicago
Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$417 | Average$733 | FlexibilityNo cancel fee | On-time70% |