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$247+ Cheap flights from Panama to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Sep 2 — Sep 91
Tue 9/2
Tue 9/9
1 adult, Economy
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Cheap flight deals from Panama to Chicago

Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated August 28, 2025.

Round-trip from

$412
(Mytrip)

One-way from

$247
(Kiwi.com)

Popular in

January

Cheapest in

July

Average price

$567

Good round-trip deal

$465 or less

Good one-way deal

$722 or less
From Panama to Chicago (CHI)
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One-way flight from Panama to Chicago (CHI)
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Highest demand for flights based on searches. 3% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Panama to Chicago (CHI).
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Price to beat on a one-way flight from Panama to Chicago (CHI).
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Find flight deals from Panama to Chicago

Cheapest flights from Panama to Chicago
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 28, 2025.

This Mytrip deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:25 pmPTY - ORD
2 stops29h 23mMultiple Airlines
Wed 10/15:05 amORD - PTY
2 stops27h 50mMultiple Airlines
Deal found 8/27$412
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/249:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Sun 9/2810:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/26$443
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/89:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Mon 9/2910:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/25$453
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Thu 10/210:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/28$458
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/89:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Sun 9/2810:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/25$462
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/239:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Sun 9/2810:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/26$464
This Mytrip deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/93:20 amPTY - ORD
2 stops19h 28mMultiple Airlines
Wed 9/1711:15 amORD - PTY
3 stops33h 55mMultiple Airlines
Deal found 8/26$471
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1410:05 pmPTY - ORD
2 stops35h 13mMultiple Airlines
Fri 9/192:35 pmORD - PTY
1 stop10h 10mMultiple Airlines
Deal found 8/26$472
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/99:33 pmPTY - ORD
1 stop11h 45mMultiple Airlines
Wed 10/110:27 amORD - PTY
1 stop9h 02mMultiple Airlines
Deal found 8/25$473
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/119:25 amPTY - MDW
1 stop13h 55mMultiple Airlines
Sat 9/206:15 amMDW - PTY
1 stop13h 18mMultiple Airlines
Deal found 8/26$583
This Delta deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:37 pmPTY - MDW
1 stop8h 55mDelta
Sun 11/306:00 amMDW - PTY
1 stop7h 12mDelta
Deal found 8/26$596
This Delta deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:21 pmPTY - MDW
1 stop7h 53mDelta
Wed 11/196:00 amMDW - PTY
1 stop7h 12mDelta
Deal found 8/27$598

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.

Fly from

Panama

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 10/7

10:05 pm-6:36 pm

2 stops20h 31m

Chicago O'Hare Intl

Tue 10/21

5:05 am-9:10 pm

2 stops16h 05m

$412

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 9/26

5:25 pm-10:48 pm

2 stops29h 23m

Chicago O'Hare Intl

Wed 10/1

5:05 am-8:55 am

2 stops27h 50m

$412

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/24

9:33 pm-9:18 am

1 stop11h 45m

Chicago O'Hare Intl

Sun 9/28

10:27 am-7:29 pm

1 stop9h 02m

$443

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Mon 9/8

9:33 pm-9:18 am

1 stop11h 45m

Chicago O'Hare Intl

Mon 9/29

10:27 am-7:29 pm

1 stop9h 02m

$453

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 9/26

9:33 pm-9:18 am

1 stop11h 45m

Chicago O'Hare Intl

Thu 10/2

10:27 am-7:29 pm

1 stop9h 02m

$458

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 9/10

5:25 pm-1:15 pm

1 stop19h 50m

Chicago O'Hare Intl

Wed 9/17

5:05 am-9:10 pm

2 stops16h 05m

$462

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Thu 9/11

9:25 am-11:20 pm

1 stop13h 55m

Chicago Midway

Sat 9/20

6:15 am-7:33 pm

1 stop13h 18m

$583

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 11/5

3:21 pm-10:14 pm

1 stop7h 53m

Chicago Midway

Wed 11/19

6:00 am-2:12 pm

1 stop7h 12m

$598

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Sat 10/11

2:21 pm-10:14 pm

1 stop7h 53m

Chicago Midway

Sat 10/18

6:00 am-12:56 pm

1 stop6h 56m

$633

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Fri 10/3

2:10 pm-8:40 am

2 stops18h 30m

Chicago Midway

Tue 10/7

6:00 am-12:56 pm

1 stop6h 56m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/26

Showing 1-10 of 26 results
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Best time to book a flight from Panama to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Chicago

What is the cheapest month to book a flight from Panama to Chicago?

Currently, August is the cheapest month in which you can book a flight from Panama to Chicago (average of $245). Flying from Panama to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CHI?

Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 28, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 18% on flights from Panama to Chicago by exploring options for tickets at noon.

Weekly flight availability from Panama to Chicago

Explore weekly flight availability from Panama to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 28, 2025.

The most flights from PA0 to CHI are scheduled on a Wednesday (8 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated August 28, 2025.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,517 reviews

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,517 reviews
Copa Airlines
7.5
Good
1,517 reviews

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,420 reviews
Copa Airlines
7.5
Good
1,517 reviews

Entertainment

6.8

Boarding

7.8

Overall

7.5

Comfort

7.4

Food

6.8

Crew

8.1

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Chicago?

    There are many flights that can get you from Panama to Chicago in 7h 53m. Fly via Delta to get the fastest option. Panama and Chicago are separated by a distance of 2316 mi.

  • What are the most popular routes from Panama to Chicago?

    The most popular flight routes from Panama to Chicago are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Marcos A. Gelabert Intl - Chicago O'Hare Intl.

  • What are the most reliable airlines from Panama to Chicago?

    No one likes to see their flight delayed. When booking a flight from Panama to Chicago consider choosing United Airlines (92%), EVA Air (91%) or Copa Airlines (90%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama to Chicago?

    The cheapest flight price from Panama to Chicago is $419. On average you can expect to pay $609. The most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl), can usually be booked for $412.

  • Can I find deals for flights from Panama to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Chicago.

  • Can I find deals for business class flights from Panama to Chicago?

    Yes. Cheapflights offers flight deals from Panama to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Panama to Chicago (average of $245). Flying from Panama to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

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Alternative routes for Panama to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
Guatemala City to O'Hare Intl flights
San José to O'Hare Intl flights
Guatemala City to Midway flights
Panama City to O'Hare Intl flights
San José to Midway flights
San Salvador to O'Hare Intl flights
San Pedro Sula to O'Hare Intl flights
Managua to O'Hare Intl flights
San Pedro Sula to Midway flights
San José to St. Louis flights
Philip S.W.Goldson to O'Hare Intl flights
Guatemala City to St. Louis flights
Panama City to St. Louis flights
Liberia to O'Hare Intl flights
San Pedro Sula to St. Louis flights
Philip S.W.Goldson to Midway flights
Coxen Hole to O'Hare Intl flights
Managua to Midway flights
Managua to St. Louis flights
Tegucigalpa to St. Louis flights
Tegucigalpa to O'Hare Intl flights
Tegucigalpa to Midway flights

Top 2 airlines flying from Panama to Chicago

Discover the top 2 airlines that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$415Average$549FlexibilityNo cancel feeOn-time70%
DeltaCheapest$569Average$671FlexibilityNo cancel feeOn-timeN/A

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