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$314+ Cheap flights from Panama to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Jul 27 — Aug 31
Mon 7/27
Mon 8/3
1 adult, Economy
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Cheap flight deals from Panama to Chicago

Cheapest flights from Panama to Chicago
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 27, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/165:55 pm
PTY
-
ORD
2 stops43h 05m
Multiple Airlines
Sat 8/227:35 am
ORD
-
PTY
1 stop10h 19m
Multiple Airlines
Deal found 6/23$625
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/510:10 am
PTY
-
ORD
2 stops13h 17m
Multiple Airlines
Fri 9/117:45 am
ORD
-
PTY
1 stop12h 34m
Multiple Airlines
Deal found 6/25$626
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:25 am
PTY
-
ORD
2 stops19h 27m
Multiple Airlines
Mon 8/317:35 am
ORD
-
PTY
1 stop12h 39m
Multiple Airlines
Deal found 6/26$661
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1010:10 am
PTY
-
ORD
2 stops26h 05m
Multiple Airlines
Sat 8/157:35 am
ORD
-
PTY
1 stop30h 30m
Multiple Airlines
Deal found 6/23$662
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/110:10 am
PTY
-
ORD
2 stops26h 05m
Multiple Airlines
Sun 8/307:35 am
ORD
-
PTY
1 stop10h 19m
Multiple Airlines
Deal found 6/24$672
This Avianca deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
Wed 7/1511:20 pm
ORD
-
PTY
1 stop17h 40m
Avianca
Deal found 6/23$680
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:10 am
PTY
-
ORD
2 stops26h 05m
Multiple Airlines
Fri 8/148:05 am
ORD
-
PTY
1 stop9h 14m
Multiple Airlines
Deal found 6/22$681
This Avianca deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/64:25 am
PTY
-
ORD
1 stop16h 55m
Avianca
Wed 9/211:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Deal found 6/24$687
This Delta deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:21 pm
PTY
-
MDW
1 stop19h 31m
Delta
Sat 10/106:00 am
MDW
-
PTY
1 stop6h 56m
Delta
Deal found 6/26$762
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:20 pm
PTY
-
MDW
1 stop19h 39m
Delta
Sat 8/2210:56 am
MDW
-
PTY
1 stop25h 59m
Delta
Deal found 6/23$763
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:23 pm
PTY
-
MDW
1 stop8h 22m
Delta
Fri 9/186:05 am
MDW
-
PTY
1 stop6h 53m
Delta
Deal found 6/23$764
This Kiwi.com deal was found by Cheapflights users on 6/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/69:33 pm
PTY
-
MDW
2 stops13h 25m
Multiple Airlines
Sun 10/116:40 am
MDW
-
PTY
1 stop13h 54m
Multiple Airlines
Deal found 6/26$781

Find flight deals from Panama to Chicago

Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated June 27, 2026.

Round-trip from

$625
(Kiwi.com)

One-way from

$314
(Kiwi.com)

Popular in

July

Cheapest in

September

Average price

$770

Good round-trip deal

$783 or less

Good one-way deal

$698 or less
From Panama to Chicago (CHI)
Search Deals
One-way flight from Panama to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($111 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Panama to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Panama to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Wed 7/15

4:25 am-9:20 pm

1 stop16h 55m

Chicago O'Hare Intl

Mon 7/20

11:20 pm-2:15 pm

1 stop14h 55m

$687

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Sun 11/1

8:05 am-12:46 pm

Nonstop5h 41m

Chicago O'Hare Intl

Sat 11/7

2:13 pm-8:37 pm

Nonstop5h 24m

$756

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 10/27

7:55 am-8:40 pm

2 stops12h 45m

Chicago O'Hare Intl

Sun 11/1

6:00 am-7:38 pm

1 stop12h 38m

$756

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 10/27

7:28 pm-1:05 am

Nonstop5h 37m

Chicago O'Hare Intl

Sun 11/1

2:13 pm-8:37 pm

Nonstop5h 24m

$756

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Tue 8/11

8:10 am-1:59 pm

Nonstop5h 49m

Chicago O'Hare Intl

Fri 8/14

8:02 am-1:22 pm

Nonstop5h 20m

$758
Quickest round-trip

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Thu 8/27

7:25 pm-1:02 am

Nonstop5h 37m

Chicago O'Hare Intl

Mon 8/31

3:21 pm-8:41 pm

Nonstop5h 20m

$758

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Wed 10/7

2:21 pm-10:10 pm

1 stop7h 49m

Chicago Midway

Sat 10/10

6:00 am-12:56 pm

1 stop6h 56m

$762

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Tue 10/6

2:21 pm-8:45 am

2 stops18h 24m

Chicago Midway

Sat 10/10

6:00 am-12:56 pm

1 stop6h 56m

$762

Panama CityChicago

PTY - ORD

PTYORD

Panama City Tocumen Intl

Fri 10/9

3:30 pm-12:25 pm

1 stop20h 55m

Chicago O'Hare Intl

Mon 10/12

9:38 pm-2:14 pm

1 stop16h 36m

$762

Panama CityChicago

PTY - MDW

PTYMDW

Panama City Tocumen Intl

Mon 10/5

2:23 pm-10:45 pm

1 stop8h 22m

Chicago Midway

Sat 10/10

6:00 am-12:56 pm

1 stop6h 56m

$762

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/24

Showing 1-10 of 40 resultsSorted by cheapest first
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Best time to book a flight from Panama to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Chicago

What is the cheapest month to book a flight from Panama to Chicago?

Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in June is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CHI?

Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 27, 2026.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.

How far ahead should I book a flight from Panama to Chicago?

The price you pay for your flight from Panama to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 51 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated June 27, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,569 reviews

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.9

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.6
Good
1,569 reviews
Copa Airlines
7.6
Good
1,569 reviews

Overall

7.6

Boarding

7.8

Crew

8.1

Food

6.9

Comfort

7.4

Entertainment

6.8

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama to Chicago?

    There are many flights that can get you from Panama to Chicago in 5h 41m. Fly via Avianca, Copa Airlines, or United Airlines to get the fastest option. Panama and Chicago are separated by a distance of 2330 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Panama to Chicago?

    The most popular flight routes from Panama to Chicago are Panama City Tocumen Intl - Chicago O'Hare Intl, Panama City Tocumen Intl - Chicago Midway and Panama City Marcos A. Gelabert Intl - Chicago O'Hare Intl.

  • What are the most reliable airlines from Panama to Chicago?

    No one likes to see their flight delayed. When booking a flight from Panama to Chicago consider choosing Copa Airlines (95%), United Airlines (92%) or EVA Air (91%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama to Chicago?

    The cheapest flight price from Panama to Chicago is $698. On average you can expect to pay $877. The most popular route, (Panama City Tocumen Intl - Chicago O'Hare Intl), can usually be booked for $626.

  • Can I find deals for flights from Panama to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Chicago.

  • Can I find deals for business class flights from Panama to Chicago?

    Yes. Cheapflights offers flight deals from Panama to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Chicago?

    Currently, October is the cheapest month in which you can book a flight from Panama to Chicago (average of $239). Flying from Panama to Chicago in June is currently the most expensive (average of $604). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Benton Harbor
Lansing
Merrillville
Hammond
Porter

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Panama to Chicago

Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$417Average$729FlexibilityNo cancel feeOn-time70%

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