$376+ Cheap flights from Panama to Chicago (CHI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHI
Dec 14 — Dec 211
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
Last-minute
One-way
Cheapest flights from Panama to ChicagoExplore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
Explore the most affordable flight options available from Panama to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:47 pm -
1 stop14h 56m
Sat 3/612:04 am -
1 stop12h 27m
Deal found 11/13![Multiple Airlines logo]()
$725
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:13 pm -
1 stop9h 43m
Thu 1/216:05 am -
1 stop8h 50m
Deal found 11/11![American Airlines logo]()
$758
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/162:47 pm -
1 stop9h 48m
Sat 1/212:04 am -
1 stop12h 29m
Deal found 11/13![Multiple Airlines logo]()
$760
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:49 pm -
1 stop9h 46m
Mon 3/112:17 am -
2 stops24h 03m
Deal found 11/10![Multiple Airlines logo]()
$761
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:13 pm -
1 stop9h 43m
Wed 1/205:59 pm -
1 stop18h 27m
Deal found 11/11![American Airlines logo]()
$764
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:49 pm -
1 stop9h 46m
Sat 1/212:04 am -
1 stop12h 29m
Deal found 11/13![Multiple Airlines logo]()
$770
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:34 pm -
1 stop17h 36m
Thu 1/216:05 am -
1 stop8h 50m
Deal found 11/11![American Airlines logo]()
$781
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:13 pm -
1 stop20h 07m
Fri 3/57:00 am -
1 stop7h 24m
Deal found 11/11![American Airlines logo]()
$782
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:34 pm -
1 stop17h 36m
Wed 1/205:59 pm -
1 stop18h 27m
Deal found 11/11![American Airlines logo]()
$786
This Copa Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/217:35 am -
1 stop24h 10m
Deal found 11/13![Copa Airlines logo]()
$1,372
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:48 am -
2 stops50h 00m
Fri 11/276:30 pm -
2 stops37h 20m
Deal found 11/10![United Airlines logo]()
$1,433
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/218:59 am -
2 stops30h 10m
Deal found 11/13![Multiple Airlines logo]()
$1,576
Best flights from Panama to ChicagoDiscover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
Discover carefully curated flight deals from Panama to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 14, 2026.
This Copa Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/197:04 pm -
Nonstop5h 40m
Fri 4/303:13 pm -
Nonstop5h 23m
Deal found 11/12![Copa Airlines logo]()
$842
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/78:00 am -
2 stops13h 32m
Fri 2/197:59 pm -
1 stop15h 16m
Deal found 11/9![Delta logo]()
$850
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:00 am -
1 stop9h 41m
Tue 12/156:50 am -
1 stop9h 22m
Deal found 11/9![United Airlines logo]()
$859
This Copa Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/67:55 am -
Nonstop5h 39m
Thu 4/158:08 am -
Nonstop5h 23m
Deal found 11/10![Copa Airlines logo]()
$842
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:00 am -
1 stop23h 48m
Mon 12/147:50 pm -
1 stop17h 55m
Deal found 11/9![United Airlines logo]()
$859
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/294:41 pm -
1 stop18h 29m
Tue 2/210:35 am -
1 stop8h 27m
Deal found 11/13![United Airlines logo]()
$859
This Copa Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:28 pm -
Nonstop5h 43m
Wed 2/107:35 am -
Nonstop5h 24m
Deal found 11/13![Copa Airlines logo]()
$860
This Copa Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:28 pm -
Nonstop5h 43m
Wed 2/107:35 am -
Nonstop5h 24m
Deal found 11/14![Copa Airlines logo]()
$860
This Copa Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:28 pm -
Nonstop5h 43m
Tue 2/92:13 pm -
Nonstop5h 23m
Deal found 11/14![Copa Airlines logo]()
$860
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:48 am -
2 stops50h 00m
Fri 11/276:30 pm -
2 stops37h 20m
Deal found 11/10![United Airlines logo]()
$1,433
This Copa Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/217:35 am -
1 stop24h 10m
Deal found 11/13![Copa Airlines logo]()
$1,372
Last-minute flights from Panama to ChicagoDiscover last-minute flight deals from Panama to Chicago. Data last updated November 14, 2026 and is based on user searches.
Discover last-minute flight deals from Panama to Chicago. Data last updated November 14, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/249:48 am -
2 stops50h 00m
Fri 11/276:30 pm -
2 stops37h 20m
Deal found 11/10![United Airlines logo]()
$1,433
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:34 pm -
1 stop17h 36m
Thu 1/216:05 am -
1 stop8h 50m
Deal found 11/11![American Airlines logo]()
$781
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/273:34 pm -
1 stop17h 36m
Wed 1/205:59 pm -
1 stop18h 27m
Deal found 11/11![American Airlines logo]()
$786
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/23:13 pm -
1 stop9h 43m
Thu 1/216:05 am -
1 stop8h 50m
Deal found 11/11![American Airlines logo]()
$758
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:13 pm -
1 stop9h 43m
Wed 1/205:59 pm -
1 stop18h 27m
Deal found 11/11![American Airlines logo]()
$764
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/122:47 pm -
1 stop14h 56m
Sat 3/612:04 am -
1 stop12h 27m
Deal found 11/13![Multiple Airlines logo]()
$725
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/162:47 pm -
1 stop9h 48m
Sat 1/212:04 am -
1 stop12h 29m
Deal found 11/13![Multiple Airlines logo]()
$760
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/163:13 pm -
1 stop20h 07m
Fri 3/57:00 am -
1 stop7h 24m
Deal found 11/11![American Airlines logo]()
$782
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:49 pm -
1 stop9h 46m
Mon 3/112:17 am -
2 stops24h 03m
Deal found 11/10![Multiple Airlines logo]()
$761
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:49 pm -
1 stop9h 46m
Sat 1/212:04 am -
1 stop12h 29m
Deal found 11/13![Multiple Airlines logo]()
$770
This Copa Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/217:35 am -
1 stop24h 10m
Deal found 11/13![Copa Airlines logo]()
$1,372
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/179:48 am -
1 stop14h 15m
Mon 12/218:59 am -
2 stops30h 10m
Deal found 11/13![Multiple Airlines logo]()
$1,576
One-way flights from Panama to ChicagoSearch for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
Search for one-way flight options from Panama to Chicago. Find affordable one-way fares based on user searches. Data last updated November 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/142:47 pm -
1 stop9h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/162:47 pm -
1 stop9h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/13![Multiple Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:49 pm -
1 stop9h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/92:26 pm -
2 stops18h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/234:55 pm -
1 stop9h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/82:26 pm -
1 stop11h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/43:24 pm -
1 stop18h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![American Airlines logo]()
$433
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/224:55 pm -
2 stops22h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$438
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/29:48 am -
3 stops28h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$2,920
Find flight deals from Panama to Chicago
Keep the following information in mind while searching for Panama to Chicago flight deals. Data was last updated November 14, 2026.
Round-trip from | $697 (American Airlines) |
|---|---|
One-way from | $376 (Kiwi.com) |
Popular in | July |
Cheapest in | April |
Average price | $805 |
Good round-trip deal | $985 or less |
Good one-way deal | $1,005 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
Use the filters below to find and compare flights from Panama to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Tue 2/9
2:26 pm-1:05 am
1 stop11h 39m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$388
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Wed 12/16
2:47 pm-11:13 am
2 stops21h 26m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$435
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Fri 12/11
6:26 pm-5:40 pm
2 stops24h 14m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$559
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Wed 11/25
3:34 pm-7:32 am
2 stops16h 58m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$609
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Sun 3/28
5:55 pm-12:39 am
3 stops30h 44m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$690
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 1/4
4:33 pm-8:20 am
2 stops16h 47m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$745
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Mon 12/14
8:06 am-12:46 pm
Nonstop5h 40m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$770
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Wed 12/16
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$770
Quickest round-trip
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Thu 12/17
6:25 pm-11:03 pm
Nonstop5h 38m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$770
Panama CityChicago
PTY Panama City Tocumen Intl - ORD Chicago O'Hare Intl
PTYORD
Panama City Tocumen Intl
Fri 12/11
7:28 pm-12:11 am
Nonstop5h 43m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$770
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from Panama to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama with our price prediction graph.
PTY-ORD
DAV-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama to Chicago
PA0-CHI
PTY-ORD
DAV-ORD
What is the cheapest month to book a flight from Panama to Chicago?
Currently, April is the cheapest month in which you can book a flight from Panama to Chicago (average of $586). Flying from Panama to Chicago in March is currently the most expensive (average of $808). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from PA to CHI?
Find hourly flight availability from Panama to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama to Chicago as you normally would.
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated November 14, 2026.
Read through reviews of airlines operating flights from Panama to Chicago, such as Copa Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.8
Food
7.0
Entertainment
6.9
Comfort
7.4
Crew
8.1
Overall
7.6
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Boarding
7.8
Food
7.0
Entertainment
6.9
Comfort
7.4
Crew
8.1
Overall
7.6
Reviews
1 / 20
2.0
MediocreMaria,Dec 2025
PTY - SLA
Related info for your journey
Find useful and relevant information for your journey from Panama to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Merrillville
Lansing
Valparaiso
Hammond
Saint Joseph
Porter
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Alternative routes for Panama to Chicago
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Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 14, 2026.
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Complete your trip to Chicago by adding a car rental and/or hotel reservation to your travel itinerary.
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Panama and Chicago flights
Browse other Panama and Chicago flight options. Last updated on November 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama to Chicago
Discover the top airline that operate flights from Panama to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$574 | Average$841 | FlexibilityNo cancel fee | On-time70% |