HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Chicago

$104+ Cheap flights from Panama City, FL (ECP) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/29. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHI
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Chicago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Chicago

Cheapest flights from Panama City to Chicago
Explore the most affordable flight options available from Panama City to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:24 am
ECP
-
ORD
Nonstop2h 44m
United Airlines
Tue 3/107:10 am
ORD
-
ECP
Nonstop2h 33m
United Airlines
Deal found 1/26$207
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:35 pm
ECP
-
MDW
1 stop4h 35m
Southwest
Fri 3/63:05 pm
MDW
-
ECP
Nonstop2h 15m
Southwest
Deal found 1/28$217
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:06 pm
ECP
-
ORD
1 stop5h 50m
Delta
Tue 3/109:50 am
ORD
-
ECP
1 stop5h 46m
Delta
Deal found 1/28$227
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
ECP
-
MDW
1 stop3h 54m
Delta
Fri 3/66:40 pm
MDW
-
ECP
1 stop3h 59m
Delta
Deal found 1/28$227
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/54:34 pm
ECP
-
ORD
1 stop7h 42m
American Airlines
Tue 3/1010:18 am
ORD
-
ECP
Nonstop2h 26m
American Airlines
Deal found 1/28$237
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/123:00 pm
ECP
-
ORD
Nonstop2h 45m
American Airlines
Mon 2/1611:58 am
ORD
-
ECP
Nonstop2h 26m
American Airlines
Deal found 1/28$247
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:06 pm
ECP
-
MDW
1 stop4h 25m
Delta
Fri 2/206:40 pm
MDW
-
ECP
1 stop3h 59m
Delta
Deal found 1/28$247
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/133:00 pm
ECP
-
ORD
Nonstop2h 45m
American Airlines
Fri 2/206:35 pm
ORD
-
ECP
1 stop5h 14m
American Airlines
Deal found 1/28$257
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:00 am
ECP
-
MDW
1 stop5h 25m
Southwest
Sun 2/155:25 am
MDW
-
ECP
1 stop4h 10m
Southwest
Deal found 1/27$267
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/51:34 pm
ECP
-
ORD
1 stop5h 55m
American Airlines
Sun 2/2211:58 am
ORD
-
ECP
Nonstop2h 26m
American Airlines
Deal found 1/27$272
This Southwest deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:00 am
ECP
-
ORD
2 stops13h 50m
Southwest
Wed 3/112:40 pm
ORD
-
ECP
1 stop4h 55m
Southwest
Deal found 1/28$278
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/53:45 pm
ECP
-
ORD
1 stop5h 15m
Delta
Sun 2/226:45 am
ORD
-
ECP
1 stop6h 35m
Delta
Deal found 1/27$282

Find flight deals from Panama City to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$207
(United Airlines)

One-way from

$104
(United Airlines)

Popular in

November

Cheapest in

July

Average price

$269

Good round-trip deal

$233 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Panama City NW Florida Beaches-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Chicago (CHI) flights.
Search Deals
From Panama City NW Florida Beaches to Chicago (CHI)
Search Deals
One-way flight from Panama City NW Florida Beaches to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals
Price to beat on a round-trip flight from Panama City NW Florida Beaches to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Panama City NW Florida Beaches to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City to Chicago that are best for you.

Fly from

Panama City

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 3/5

3:00 pm-5:45 pm

Nonstop2h 45m

Chicago O'Hare Intl

Tue 3/10

11:58 am-2:24 pm

Nonstop2h 26m

$207

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 3/5

10:24 am-1:08 pm

Nonstop2h 44m

Chicago O'Hare Intl

Tue 3/10

7:10 am-9:43 am

Nonstop2h 33m

$207

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 2/27

12:35 pm-5:10 pm

1 stop4h 35m

Chicago Midway

Fri 3/6

3:05 pm-5:20 pm

Nonstop2h 15m

$217

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 3/25

5:30 pm-11:54 pm

1 stop6h 24m

Chicago O'Hare Intl

Tue 3/31

5:30 am-10:23 am

1 stop4h 53m

$227

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Fri 5/15

1:30 pm-7:01 pm

1 stop5h 31m

Chicago O'Hare Intl

Mon 5/18

1:15 pm-7:36 pm

1 stop6h 21m

$227

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 3/5

6:00 am-10:14 am

1 stop4h 14m

Chicago O'Hare Intl

Tue 3/10

5:30 am-10:23 am

1 stop4h 53m

$227

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 7/2

6:00 am-12:09 pm

1 stop6h 09m

Chicago O'Hare Intl

Thu 7/9

1:15 pm-7:37 pm

1 stop6h 22m

$227

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 2/27

6:00 am-9:54 am

1 stop3h 54m

Chicago Midway

Fri 3/6

6:40 pm-10:39 pm

1 stop3h 59m

$227

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Fri 2/13

2:05 pm-9:01 pm

1 stop6h 56m

Chicago O'Hare Intl

Fri 2/20

5:25 am-11:25 am

1 stop6h 00m

$247

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 2/13

6:06 pm-10:31 pm

1 stop4h 25m

Chicago Midway

Fri 2/20

12:45 pm-7:30 pm

1 stop6h 45m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 40 results
1
2
3
4

Compare providers for flights from Panama City to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Chicago in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Chicago

What is the cheapest month to book a flight from Panama City, Florida to Chicago?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $108). Flying from Panama City, Florida to Chicago in April is currently the most expensive (average of $219). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CHI?

Find hourly flight availability from Panama City to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 30% on flights from Panama City, Florida to Chicago by exploring options for tickets at noon.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Panama City to Chicago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Chicago?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Chicago. On average, NW Florida Beaches has 0 outbound flights to Chicago per day from 4 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Chicago?

    There are many flights that can get you from Panama City, Florida to Chicago in 2h 44m. Fly via American Airlines, United Airlines, or Southwest to get the fastest option. The distance between Panama City, Florida and Chicago is about 811 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City, Florida to Chicago round-trip?

    Currently priced at $89, Delta will fly you from Panama City, Florida to Chicago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $209 and $209, respectively. Delta is currently priced 71% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Chicago one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to Chicago are Southwest ($87), Delta ($98), and United Airlines ($114).

  • What are the most reliable airlines from Panama City, Florida to Chicago?

    Consider United Airlines (84%), Republic Airways (84%) or American Airlines (0%) when booking your flight. These represent the most reliable airlines when flying from Panama City, Florida to Chicago.

  • What are the cheapest flights from Panama City, Florida to Chicago?

    Looking at all options, your cheapest flight can be booked for $149. While the most popular route (Panama City NW Florida Beaches - Chicago O'Hare Intl) can be booked for $207 on average, our data indicates $1,495 when flying from Panama City, Florida to Chicago.

  • Can I find deals for flights from Panama City to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama City to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Chicago.

  • Can I find deals for business class flights from Panama City to Chicago?

    Yes. Cheapflights offers flight deals from Panama City to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Chicago?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $108). Flying from Panama City, Florida to Chicago in April is currently the most expensive (average of $219). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lansing
Merrillville
Hammond
Porter
Benton Harbor

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to O'Hare Intl flights
Tampa to O'Hare Intl flights
Miami to O'Hare Intl flights
Fort Lauderdale to O'Hare Intl flights
Orlando to Midway flights
Miami to Midway flights
Tampa to Midway flights
Jacksonville to O'Hare Intl flights
Orlando to St. Louis flights
Fort Lauderdale to Midway flights
West Palm Beach to O'Hare Intl flights
Fort Myers to O'Hare Intl flights
Tampa to St. Louis flights
Sarasota to O'Hare Intl flights
Pensacola to O'Hare Intl flights
Fort Lauderdale to St. Louis flights
Jacksonville to Midway flights
Fort Myers to Midway flights
Miami to St. Louis flights
West Palm Beach to Midway flights
Valparaiso to O'Hare Intl flights
Panama City to O'Hare Intl flights
Jacksonville to St. Louis flights
Sarasota to Midway flights
Pensacola to Midway flights
Sarasota to St. Louis flights
Fort Myers to St. Louis flights
Valparaiso to Midway flights
West Palm Beach to St. Louis flights
Jacksonville to Moline flights
Pensacola to St. Louis flights
Fort Lauderdale to Rockford flights
Gainesville to O'Hare Intl flights
Panama City to Midway flights
Key West to O'Hare Intl flights
Tallahassee to O'Hare Intl flights
Jacksonville to Peoria flights
Tampa to Moline flights
Orlando to Moline flights
Valparaiso to St. Louis flights
Daytona Beach to O'Hare Intl flights
Orlando to Peoria flights
Orlando to Bloomington flights
Melbourne to O'Hare Intl flights
Gainesville to Midway flights
Pensacola to Peoria flights
Tampa to Peoria flights
Tallahassee to Midway flights
Orlando Sanford Intl to Rockford flights

Top 4 airlines flying from Panama City to Chicago

Discover the top 4 airlines that operate flights from Panama City to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$89Average$262FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$209Average$338FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$209Average$326FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$219Average$354FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.