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$109+ Cheap flights from Panama City, FL (ECP) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHI
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City NW Florida Beaches to Chicago are usually found in February or July, booked 61 days in advance, depart on a Thursday or Wednesday and return on a Tuesday

Cheap flight deals from Panama City to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 31, 2025.

Round-trip from

$217
(United Airlines)

One-way from

$109
(United Airlines)

Popular in

April

Cheapest in

February

Average price

$228

Good round-trip deal

$386 or less

Good one-way deal

$173 or less
From Panama City NW Florida Beaches to Chicago (CHI)
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One-way flight from Panama City NW Florida Beaches to Chicago (CHI)
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Highest demand for flights based on searches. 12% potential increase in price ($46 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a round-trip flight from Panama City NW Florida Beaches to Chicago (CHI).
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Price to beat on a one-way flight from Panama City NW Florida Beaches to Chicago (CHI).
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Find flight deals from Panama City to Chicago

Cheapest flights from Panama City to Chicago
Explore the most affordable flight options available from Panama City to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:11 pmECP - ORD
Nonstop2h 39mUnited Airlines
Mon 9/2910:40 amORD - ECP
Nonstop2h 30mUnited Airlines
Deal found 7/31$217
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:10 pmECP - MDW
Nonstop2h 10mSouthwest
Tue 9/306:25 amMDW - ECP
1 stop3h 45mSouthwest
Deal found 7/29$227
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/176:00 amECP - ORD
1 stop4h 10mDelta
Tue 9/2311:20 amORD - ECP
1 stop4h 31mDelta
Deal found 7/31$237
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:00 amECP - MDW
1 stop5h 48mDelta
Sat 8/234:25 pmMDW - ECP
1 stop6h 41mDelta
Deal found 7/29$237
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/97:40 amECP - ORD
2 stops10h 15mSouthwest
Tue 9/167:30 amORD - ECP
1 stop5h 00mSouthwest
Deal found 7/30$242
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/287:06 pmECP - ORD
1 stop4h 42mAmerican Airlines
Tue 9/26:55 amORD - ECP
1 stop5h 53mAmerican Airlines
Deal found 7/29$283

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Panama City to Chicago that are best for you.

Fly from

Panama City

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 9/24

5:11 pm-7:50 pm

Nonstop2h 39m

Chicago O'Hare Intl

Mon 9/29

10:40 am-1:10 pm

Nonstop2h 30m

$217

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 9/27

4:10 pm-6:20 pm

Nonstop2h 10m

Chicago Midway

Tue 9/30

6:25 am-10:10 am

1 stop3h 45m

$227

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 9/17

6:00 am-10:10 am

1 stop4h 10m

Chicago O'Hare Intl

Tue 9/23

11:20 am-3:51 pm

1 stop4h 31m

$237

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Tue 8/19

6:00 am-11:48 am

1 stop5h 48m

Chicago Midway

Sat 8/23

4:25 pm-11:06 pm

1 stop6h 41m

$237

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Tue 9/9

7:40 am-5:55 pm

2 stops10h 15m

Chicago O'Hare Intl

Tue 9/16

7:30 am-12:30 pm

1 stop5h 00m

$242

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 8/28

7:06 pm-11:48 pm

1 stop4h 42m

Chicago O'Hare Intl

Tue 9/2

6:55 am-12:48 pm

1 stop5h 53m

$283

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 9/6

5:11 pm-7:50 pm

Nonstop2h 39m

$109

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Sat 8/30

4:10 pm-6:20 pm

Nonstop2h 10m

$109

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Wed 10/29

6:00 am-12:16 pm

1 stop6h 16m

$119

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Wed 10/29

9:29 am-4:09 pm

1 stop6h 40m

$119

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 12 results
1
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Best time to book a flight from Panama City to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Chicago

How far ahead should I book a flight from Panama City, Florida to Chicago?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Chicago. Price data was last updated on July 25, 2025.

The price you pay for your flight from Panama City, Florida to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 61 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City, Florida to Chicago?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $245). Flying from Panama City, Florida to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CHI?

Find hourly flight availability from Panama City to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 18% on flights from Panama City, Florida to Chicago by exploring options for tickets in the afternoon.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated July 31, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Panama City to Chicago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
United Airlines
7.4
Good
8,900 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Entertainment

7.5

Comfort

8.0

Boarding

8.1

Food

7.0

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Chicago?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Chicago. On average, NW Florida Beaches has 1 outbound flight to Chicago per day from 4 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • What are the cheapest airlines flying from Panama City, Florida to Chicago round-trip?

    Currently priced at $217, United Airlines will fly you from Panama City, Florida to Chicago and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Southwest and Delta - these airlines can fly you to your destination from $227 and $237, respectively. United Airlines is currently priced 32% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City, Florida to Chicago one-way?

    The cheapest airlines for a one-way flight from Panama City, Florida to Chicago are United Airlines ($109), Southwest ($109), and Delta ($119).

  • What are the most reliable airlines from Panama City, Florida to Chicago?

    Consider Qatar Airways (100%), Republic Airways (89%) or American Airlines (83%) when booking your flight. These represent the most reliable airlines when flying from Panama City, Florida to Chicago.

  • What are the cheapest flights from Panama City, Florida to Chicago?

    Looking at all options, your cheapest flight can be booked for $108. While the most popular route (Panama City NW Florida Beaches - Chicago O'Hare Intl) can be booked for $217 on average our data indicates $1,644 when flying from Panama City, Florida to Chicago.

  • Can I find deals for flights from Panama City to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama City to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Chicago.

  • Can I find deals for business class flights from Panama City to Chicago?

    Yes. Cheapflights offers flight deals from Panama City to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $245). Flying from Panama City, Florida to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Valparaiso
Chesterton

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Top 4 airlines flying from Panama City to Chicago

Discover the top 4 airlines that operate flights from Panama City to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$285FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$342FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$228Average$379FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$234Average$387FlexibilityNo cancel feeOn-time69%

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