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$115+ Cheap flights from Panama City, FL (ECP) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHI
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Panama City to Chicago

Cheapest flights from Panama City to Chicago
Explore the most affordable flight options available from Panama City to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/182:10 pmECP - ORD
Nonstop2h 44mUnited Airlines
Sun 12/2110:45 amORD - ECP
Nonstop2h 42mUnited Airlines
Deal found 10/28$225
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/225:00 pmECP - ORD
1 stop5h 30mDelta
Thu 11/275:08 pmORD - ECP
1 stop5h 59mDelta
Deal found 10/29$229
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:40 pmECP - MDW
1 stop5h 00mDelta
Thu 11/275:34 pmMDW - ECP
1 stop5h 33mDelta
Deal found 10/29$229
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:23 pmECP - ORD
1 stop6h 08mAmerican Airlines
Mon 12/153:52 pmORD - ECP
2 stops7h 18mAmerican Airlines
Deal found 10/30$234
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:11 amECP - MDW
1 stop5h 27mDelta
Sun 11/3010:47 amMDW - ECP
1 stop4h 39mDelta
Deal found 10/29$249
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:02 amECP - ORD
1 stop5h 17mDelta
Sun 11/165:23 amORD - ECP
1 stop5h 03mDelta
Deal found 10/28$269
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amECP - MDW
1 stop3h 52mDelta
Sat 11/156:00 amMDW - ECP
1 stop4h 26mDelta
Deal found 10/29$269
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:04 amECP - ORD
1 stop6h 51mAmerican Airlines
Mon 11/173:50 pmORD - ECP
2 stops7h 25mAmerican Airlines
Deal found 10/29$274
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:10 pmECP - ORD
Nonstop2h 44mUnited Airlines
Tue 12/3010:45 amORD - ECP
Nonstop2h 42mUnited Airlines
Deal found 10/29$279
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/201:32 pmECP - ORD
1 stop5h 20mDelta
Fri 11/285:23 amORD - ECP
1 stop5h 03mDelta
Deal found 10/29$284
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:40 pmECP - MDW
1 stop5h 00mDelta
Fri 11/286:00 amMDW - ECP
1 stop6h 47mDelta
Deal found 10/29$284
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/87:15 amECP - MDW
2 stops9h 35mSouthwest
Mon 12/158:10 amMDW - ECP
1 stop6h 30mSouthwest
Deal found 10/28$289

Cheap flight deals from Panama City to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$225
(United Airlines)

One-way from

$115
(Delta)

Popular in

November

Cheapest in

February

Average price

$308

Good round-trip deal

$289 or less

Good one-way deal

$143 or less
Provider with most accurate pricing for Panama City NW Florida Beaches-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Chicago (CHI) flights.
Search Deals
From Panama City NW Florida Beaches to Chicago (CHI)
Search Deals
One-way flight from Panama City NW Florida Beaches to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($15 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals
Price to beat on a round-trip flight from Panama City NW Florida Beaches to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Panama City NW Florida Beaches to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Panama City to Chicago that are best for you.

Fly from

Panama City

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 12/18

2:10 pm-4:54 pm

Nonstop2h 44m

Chicago O'Hare Intl

Sun 12/21

10:45 am-1:27 pm

Nonstop2h 42m

$225

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 12/25

2:10 pm-4:54 pm

Nonstop2h 44m

Chicago O'Hare Intl

Mon 12/29

10:45 am-1:27 pm

Nonstop2h 42m

$225

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Tue 12/23

11:06 am-4:19 pm

1 stop5h 13m

Chicago O'Hare Intl

Tue 12/30

6:45 am-1:19 pm

1 stop6h 34m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Mon 12/8

10:00 am-4:45 pm

1 stop6h 45m

Chicago O'Hare Intl

Sun 12/14

4:20 pm-11:06 pm

1 stop6h 46m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Fri 12/19

6:00 am-12:10 pm

1 stop6h 10m

Chicago O'Hare Intl

Sun 1/4

5:30 am-10:17 am

1 stop4h 47m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Tue 11/25

6:40 pm-12:02 am

1 stop5h 22m

Chicago O'Hare Intl

Wed 12/3

6:10 pm-10:37 pm

1 stop4h 27m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Tue 12/30

9:22 am-4:19 pm

1 stop6h 57m

Chicago O'Hare Intl

Sat 1/3

5:30 am-10:17 am

1 stop4h 47m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Sat 11/22

5:00 pm-10:30 pm

1 stop5h 30m

Chicago O'Hare Intl

Thu 11/27

5:08 pm-11:07 pm

1 stop5h 59m

$229

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Mon 12/8

10:00 am-4:45 pm

1 stop6h 45m

Chicago O'Hare Intl

Mon 12/15

6:45 am-12:47 pm

1 stop6h 02m

$229

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 11/20

6:00 am-9:52 am

1 stop3h 52m

Chicago Midway

Mon 12/1

12:47 pm-5:55 pm

1 stop5h 08m

$229

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 45 results
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Compare providers for flights from Panama City to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Chicago in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Chicago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-Chicago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Chicago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Chicago

What is the cheapest month to book a flight from Panama City, Florida to Chicago?

Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $99). Flying from Panama City, Florida to Chicago in April is currently the most expensive (average of $221). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to CHI?

Find hourly flight availability from Panama City to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 36% on flights from Panama City, Florida to Chicago by exploring options for tickets in the afternoon.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated October 30, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Panama City to Chicago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
7.9
Good
7,993 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,242 reviews

Overall

8.0

Boarding

8.1

Food

7.0

Crew

8.6

Entertainment

7.5

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Chicago?

    Most people fly from Panama City NW Florida Beaches (ECP) if they book a flight from Panama City to Chicago. On average, NW Florida Beaches has 0 outbound flights to Chicago per day from 4 airlines. Panama City NW Florida Beaches is conveniently located just 16.0 mi from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Chicago?

    There are many flights that can get you from Panama City, Florida to Chicago in 2h 44m. Fly via United Airlines or Delta to get the fastest option. The distance between Panama City, Florida and Chicago is about 811 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City, Florida to Chicago round-trip?

    Currently priced at $196, Delta will fly you from Panama City, Florida to Chicago and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and Southwest - these airlines can fly you to your destination from $219 and $228, respectively. Delta is currently priced 36% below the average price you’ll pay for this route.

  • What are the most reliable airlines from Panama City, Florida to Chicago?

    Consider Republic Airways (93%), United Airlines (70%) or SkyWest Airlines (0%) when booking your flight. These represent the most reliable airlines when flying from Panama City, Florida to Chicago.

  • What are the cheapest flights from Panama City, Florida to Chicago?

    Looking at all options, your cheapest flight can be booked for $209. While the most popular route (Panama City NW Florida Beaches - Chicago O'Hare Intl) can be booked for $209 on average, our data indicates $1,652 when flying from Panama City, Florida to Chicago.

  • Can I find deals for flights from Panama City to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama City to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Chicago.

  • Can I find deals for business class flights from Panama City to Chicago?

    Yes. Cheapflights offers flight deals from Panama City to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Chicago?

    Currently, June is the cheapest month in which you can book a flight from Panama City, Florida to Chicago (average of $99). Flying from Panama City, Florida to Chicago in April is currently the most expensive (average of $221). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Porter
Benton Harbor

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Top 4 airlines flying from Panama City to Chicago

Discover the top 4 airlines that operate flights from Panama City to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$287FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$219Average$334FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$368FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$228Average$354FlexibilityNo cancel feeOn-time63%

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