$133+ Cheap flights from Myrtle Beach (MYR) to Chicago (CHI)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHI
Oct 9 — Oct 161
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Chicago
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Cheapest flights from Myrtle Beach to ChicagoExplore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
Explore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:36 am -
1 stop14h 07m
Sat 10/317:15 am -
2 stops25h 36m
Deal found 9/8![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:36 am -
1 stop14h 07m
Fri 10/308:00 am -
1 stop24h 13m
Deal found 9/9![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:50 am -
1 stop29h 30m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:40 pm -
1 stop25h 05m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:53 pm -
1 stop26h 27m
Mon 10/198:04 am -
1 stop24h 51m
Deal found 9/7![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:53 pm -
1 stop26h 27m
Mon 10/268:04 am -
1 stop24h 51m
Deal found 9/5![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
1 stop20h 20m
Mon 10/268:04 am -
1 stop24h 51m
Deal found 9/7![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:03 pm -
1 stop24h 17m
Wed 10/218:04 am -
1 stop29h 59m
Deal found 9/5![Multiple Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop25h 48m
Sat 10/244:41 pm -
1 stop15h 06m
Deal found 9/5![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:59 am -
2 stops13h 46m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
Nonstop2h 10m
Tue 10/203:05 pm -
Nonstop1h 55m
Deal found 9/8![Southwest logo]()
$343
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:40 am -
Nonstop2h 10m
Mon 10/194:20 pm -
Nonstop1h 55m
Deal found 9/8![Southwest logo]()
$356
Best flights from Myrtle Beach to ChicagoDiscover carefully curated flight deals from Myrtle Beach to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
Discover carefully curated flight deals from Myrtle Beach to Chicago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 9, 2026.
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/296:40 am -
Nonstop2h 10m
Sat 10/316:45 am -
1 stop4h 25m
Deal found 9/9![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:54 am -
1 stop6h 17m
Mon 10/196:04 am -
1 stop6h 27m
Deal found 9/7![Delta logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:25 pm -
2 stops22h 05m
Thu 10/158:04 am -
1 stop8h 21m
Deal found 9/9![Multiple Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:00 pm -
Nonstop2h 36m
Wed 10/2111:55 am -
Nonstop2h 21m
Deal found 9/5![United Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:15 am -
1 stop4h 45m
Wed 10/283:05 pm -
Nonstop1h 55m
Deal found 9/9![Southwest logo]()
$353
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2311:27 am -
1 stop6h 05m
Fri 10/306:30 am -
1 stop6h 00m
Deal found 9/8![Delta logo]()
$389
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:50 am -
Nonstop2h 10m
Wed 10/211:05 pm -
2 stops5h 25m
Deal found 9/9![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:00 pm -
Nonstop2h 36m
Sun 10/1811:55 am -
Nonstop2h 15m
Deal found 9/5![United Airlines logo]()
$427
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:50 am -
Nonstop2h 10m
Sat 10/248:05 am -
Nonstop1h 55m
Deal found 9/7![Southwest logo]()
$365
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/35:25 pm -
1 stop5h 50m
Sat 2/68:58 am -
1 stop6h 51m
Deal found 9/9![United Airlines logo]()
$443
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:10 pm -
2 stops8h 50m
Wed 10/213:05 pm -
Nonstop1h 55m
Deal found 9/5![Southwest logo]()
$380
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 pm -
Nonstop2h 36m
Mon 10/1211:55 am -
Nonstop2h 21m
Deal found 9/7![United Airlines logo]()
$449
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:15 am -
1 stop4h 20m
Fri 10/24:30 pm -
1 stop4h 10m
Deal found 9/8![Southwest logo]()
$396
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/245:00 pm -
Nonstop2h 36m
Tue 9/2911:55 am -
Nonstop2h 21m
Deal found 9/5![United Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/61:40 pm -
2 stops10h 15m
Wed 11/1112:45 pm -
1 stop5h 35m
Deal found 9/7![Southwest logo]()
$412
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:52 am -
2 stops10h 53m
Mon 12/75:30 am -
1 stop7h 03m
Deal found 9/9![Delta logo]()
$606
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/285:54 pm -
1 stop7h 07m
Fri 10/301:55 pm -
2 stops19h 26m
Deal found 9/9![United Airlines logo]()
$542
Last-minute flights from Myrtle Beach to ChicagoDiscover last-minute flight deals from Myrtle Beach to Chicago. Data last updated September 9, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Chicago. Data last updated September 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:50 am -
1 stop29h 30m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:40 pm -
1 stop25h 05m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/111:59 am -
2 stops13h 46m
Tue 10/208:04 am -
1 stop24h 09m
Deal found 9/8![Multiple Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:40 am -
Nonstop2h 10m
Tue 10/203:05 pm -
Nonstop1h 55m
Deal found 9/8![Southwest logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:53 pm -
1 stop26h 27m
Mon 10/198:04 am -
1 stop24h 51m
Deal found 9/7![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:53 pm -
1 stop26h 27m
Mon 10/268:04 am -
1 stop24h 51m
Deal found 9/5![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:03 pm -
1 stop24h 17m
Wed 10/218:04 am -
1 stop29h 59m
Deal found 9/5![Multiple Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:40 am -
Nonstop2h 10m
Mon 10/194:20 pm -
Nonstop1h 55m
Deal found 9/8![Southwest logo]()
$356
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop25h 48m
Sat 10/244:41 pm -
1 stop15h 06m
Deal found 9/5![Multiple Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
1 stop20h 20m
Mon 10/268:04 am -
1 stop24h 51m
Deal found 9/7![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:36 am -
1 stop14h 07m
Sat 10/317:15 am -
2 stops25h 36m
Deal found 9/8![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:36 am -
1 stop14h 07m
Fri 10/308:00 am -
1 stop24h 13m
Deal found 9/9![Multiple Airlines logo]()
$258
One-way flights from Myrtle Beach to ChicagoSearch for one-way flight options from Myrtle Beach to Chicago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
Search for one-way flight options from Myrtle Beach to Chicago. Find affordable one-way fares based on user searches. Data last updated September 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/95:58 pm -
1 stop16h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:03 pm -
1 stop24h 17m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/212:42 pm -
1 stop25h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:53 pm -
1 stop26h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:10 pm -
1 stop20h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:58 pm -
2 stops22h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/191:53 pm -
1 stop26h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:12 pm -
2 stops22h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/19:36 am -
1 stop14h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:03 pm -
2 stops21h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:03 pm -
2 stops21h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:03 pm -
2 stops26h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Multiple Airlines logo]()
$168
Find flight deals from Myrtle Beach to Chicago
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $250 (Kiwi.com) |
One-way from | $133 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $375 |
Good round-trip deal | $350 or less |
Good one-way deal | $253 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Mon 11/2
11:27 am-4:32 pm
1 stop6h 05m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Sat 2/27
12:40 pm-6:55 pm
1 stop7h 15m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Wed 11/4
6:00 am-10:43 am
1 stop5h 43m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Tue 9/29
11:00 am-4:55 pm
1 stop6h 55m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Mon 11/2
10:45 am-4:10 pm
1 stop6h 25m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$182
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Sun 11/1
9:36 am-11:47 pm
2 stops39h 11m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$183
Myrtle BeachChicago
MYR Myrtle Beach Intl - MDW Chicago Midway
MYRMDW
Myrtle Beach Intl
Mon 11/23
1:40 pm-8:05 pm
2 stops7h 25m
Chicago Midway
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$187
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Fri 11/6
4:30 pm-8:38 pm
1 stop5h 08m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Sat 1/23
6:00 am-10:07 am
1 stop5h 07m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
Myrtle BeachChicago
MYR Myrtle Beach Intl - ORD Chicago O'Hare Intl
MYRORD
Myrtle Beach Intl
Sat 3/6
4:00 pm-10:20 pm
1 stop7h 20m
Chicago O'Hare Intl
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
Showing 1-10 of 38 resultsSorted by cheapest first
Compare providers for flights from Myrtle Beach to Chicago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Chicago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Chicago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Chicago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Chicago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Chicago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Chicago
Have a flexible travel schedule? Discover the best time to fly to Chicago from Myrtle Beach with our price prediction graph.
MYR-CHI
MYR-ORD
MYR-MDW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to Chicago
MYR-CHI
MYR-ORD
MYR-MDW
What is the cheapest month to book a flight from Myrtle Beach to Chicago?
Currently, January is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $261). Flying from Myrtle Beach to Chicago in July is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MYR to CHI?
Find hourly flight availability from Myrtle Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 9, 2026.
A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Chicago in the afternoon. If you’re flexible enough to do this you can expect to save up to 47% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Myrtle Beach to Chicago?
Airfare is below average for this route at the moment.
Myrtle Beach to Chicago flights typically cost between $259 and $486 in October.The cheapest round-trip price found within the last 5 days was $250 on Frontier (Oct 29-Oct 31).
The best insider tips for Myrtle Beach to Chicago flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Myrtle Beach to Chicago trip
Our travel experts
Reviews of airlines servicing Chicago
Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 9, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Myrtle Beach to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Boarding
8.1
Overall
8.0
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago?
Book flights to Chicago if you plan to visit one of these locationsBenton Harbor
Merrillville
Lansing
Valparaiso
Hammond
Saint Joseph
Porter
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Other flights to Chicago
Explore flights to Chicago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
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Myrtle Beach and Chicago flights
Browse other Myrtle Beach and Chicago flight options. Last updated on September 9, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on September 9, 2026.
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Top 3 airlines flying from Myrtle Beach to Chicago
Discover the top 3 airlines that operate flights from Myrtle Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$238 | Average$417 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$280 | Average$418 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$299 | Average$433 | FlexibilityNo cancel fee | On-time71% |