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$67+ Cheap flights from Myrtle Beach (MYR) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHI
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Myrtle Beach Intl to Chicago are usually found in September or August, booked 29 days in advance, depart on a Friday or Thursday and return on a Friday

Cheap flight deals from Myrtle Beach to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$153
(American Airlines)

One-way from

$67
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$224

Good round-trip deal

$261 or less

Good one-way deal

$119 or less
From Myrtle Beach Intl to Chicago (CHI)
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One-way flight from Myrtle Beach Intl to Chicago (CHI)
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Highest demand for flights based on searches. 18% potential increase in price ($68 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Myrtle Beach Intl to Chicago (CHI).
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Price to beat on a one-way flight from Myrtle Beach Intl to Chicago (CHI).
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Find flight deals from Myrtle Beach to Chicago

Cheapest flights from Myrtle Beach to Chicago
Explore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/111:20 amMYR - ORD
1 stop7h 03mAmerican Airlines
Sat 10/46:10 amORD - MYR
1 stop7h 04mAmerican Airlines
Deal found 9/10$153
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:15 pmMYR - ORD
1 stop6h 43mSpirit Airlines
Sat 10/411:57 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/11$161
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/87:00 amMYR - ORD
1 stop11h 53mMultiple Airlines
Sat 10/112:45 pmORD - MYR
1 stop23h 19mMultiple Airlines
Deal found 9/10$163
This Southwest deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:50 pmMYR - MDW
Nonstop2h 15mSouthwest
Sun 11/164:40 pmMDW - MYR
Nonstop1h 55mSouthwest
Deal found 9/10$165
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:04 pmMYR - ORD
1 stop15h 22mFrontier
Sun 11/165:11 amORD - MYR
1 stop9h 53mFrontier
Deal found 9/10$166
This Cheapflightsfares deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/244:15 pmMYR - ORD
1 stop6h 43mSpirit Airlines
Mon 9/2911:57 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/9$167
This Cheapflightsfares deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/269:11 amMYR - ORD
1 stop8h 40mSpirit Airlines
Mon 9/2911:57 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/10$168
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/211:20 amMYR - ORD
1 stop7h 03mAmerican Airlines
Tue 10/71:14 pmORD - MYR
1 stop4h 37mAmerican Airlines
Deal found 9/10$169
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/65:04 pmMYR - ORD
1 stop28h 38mMultiple Airlines
Mon 11/1010:18 amORD - MYR
1 stop8h 17mMultiple Airlines
Deal found 9/10$170
This Cheapflightsfares deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:00 amMYR - ORD
1 stop11h 53mSpirit Airlines
Thu 10/2311:55 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/11$174
This Priceline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:14 amMYR - ORD
1 stop7h 31mSpirit Airlines
Sun 11/211:55 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/9$176
This Cheapflightsfares deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:15 pmMYR - ORD
1 stop6h 43mSpirit Airlines
Sun 10/511:55 amORD - MYR
1 stop7h 09mSpirit Airlines
Deal found 9/8$182

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Myrtle Beach

Fly to

Chicago

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 10/1

4:15 pm-9:58 pm

1 stop6h 43m

Chicago O'Hare Intl

Sat 10/4

11:57 am-8:06 pm

1 stop7h 09m

$161

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 10/8

7:00 am-5:53 pm

1 stop11h 53m

Chicago O'Hare Intl

Sat 10/11

11:55 am-8:04 pm

1 stop7h 09m

$167

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 10/1

4:15 pm-9:58 pm

1 stop6h 43m

Chicago O'Hare Intl

Fri 10/3

11:57 am-8:06 pm

1 stop7h 09m

$169

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 10/1

4:15 pm-9:58 pm

1 stop6h 43m

Chicago O'Hare Intl

Sun 10/5

11:55 am-8:04 pm

1 stop7h 09m

$182

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 9/25

5:20 pm-9:58 pm

1 stop5h 38m

Chicago O'Hare Intl

Sun 9/28

6:30 am-4:25 pm

1 stop8h 55m

$184

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 9/26

9:11 am-4:51 pm

1 stop8h 40m

Chicago O'Hare Intl

Sun 9/28

6:30 am-4:25 pm

1 stop8h 55m

$185

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 11/6

5:04 pm-8:42 pm

1 stop28h 38m

Chicago O'Hare Intl

Mon 11/10

9:47 pm-10:41 am

2 stops11h 54m

$186

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 3/3

12:45 pm-5:51 pm

1 stop6h 06m

Chicago O'Hare Intl

Wed 3/4

5:50 am-1:29 pm

1 stop6h 39m

$197

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Tue 3/3

10:55 am-4:25 pm

1 stop6h 30m

Chicago Midway

Wed 3/4

1:05 pm-5:56 pm

1 stop3h 51m

$197

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 11/13

5:04 pm-4:56 pm

2 stops24h 52m

Chicago O'Hare Intl

Sun 11/16

5:11 am-4:04 pm

1 stop9h 53m

$199

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 45 results
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The best insider tips for Myrtle Beach to Chicago flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Myrtle Beach to Chicago trip
Airports
MYR

MYR offers short security lines and a casual atmosphere, making it stress-free for travelers. Check-in desks are available for all airlines.

Read more about MYRby Daniel Scheffler
MDW

The Orange Line train connects MDW to downtown Chicago in under 30 minutes, offering a convenient and affordable transportation option.

Read more about MDWby Ramsey Qubein
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MDW

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on MYR

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Best time to book a flight from Myrtle Beach to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Chicago

How far ahead should I book a flight from Myrtle Beach to Chicago?

Use this chart to determine the optimal time to book a round-trip flight from Myrtle Beach to Chicago. Price data was last updated on August 29, 2025.

The price you pay for your flight from Myrtle Beach to Chicago may vary depending on when you book. For the best chance of a lower fare, look to book 29 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Myrtle Beach to Chicago?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $245). Flying from Myrtle Beach to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to CHI?

Find hourly flight availability from Myrtle Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Chicago at noon. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the morning.

What is the cheapest day to fly from Myrtle Beach to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Chicago. Price data was last updated on September 7, 2025.

Travelers seeking maximum savings on their Myrtle Beach to Chicago flight should consider departing on Friday at noon when fares are most often at their lowest. Tuesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Myrtle Beach to Chicago

Explore weekly flight availability from Myrtle Beach to Chicago. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 11, 2025.

The most flights from MYR to CHI are scheduled on a Monday (3 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Myrtle Beach to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,937 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,023 reviews
Southwest
8.0
Very good
4,248 reviews

Overall

8.0

Food

7.0

Boarding

8.1

Comfort

8.0

Entertainment

7.5

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Chicago?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Chicago. 5 airlines have flights from Myrtle Beach Intl to Chicago on a regular basis. Booking flights from Myrtle Beach Intl to Chicago should not be difficult; the airport handles an average of 2 outbound flights to Chicago per day.

  • How long is the flight from Myrtle Beach to Chicago?

    For as low as $224, Spirit Airlines can have you in Chicago from Myrtle Beach in 2h 10m. There are 738 mi between Myrtle Beach and Chicago. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Myrtle Beach to Chicago round-trip?

    Flying on Spirit Airlines is currently your cheapest option to Chicago, with prices starting at $46. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $167 and $193, respectively. You may be able to fly from Myrtle Beach to Chicago for 84% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Myrtle Beach to Chicago one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $67. Users have also found prices from $67 and $77 on Southwest and American Airlines, respectively.

  • What are the most reliable airlines from Myrtle Beach to Chicago?

    Consider Republic Airways (100%), SkyWest Airlines (92%) or Qatar Airways (78%) when booking your flight. These represent the most reliable airlines when flying from Myrtle Beach to Chicago.

  • What are the cheapest flights from Myrtle Beach to Chicago?

    Looking at all options, your cheapest flight can be booked for $99. While the most popular route (Myrtle Beach Intl - Chicago O'Hare Intl) can be booked for $163 on average, our data indicates $670 when flying from Myrtle Beach to Chicago.

  • Can I find deals for flights from Myrtle Beach to Chicago that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Chicago.

  • Can I find deals for business class flights from Myrtle Beach to Chicago?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $245). Flying from Myrtle Beach to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

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Alternative routes for Myrtle Beach to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Myrtle Beach to Chicago

Discover the top 5 airlines that operate flights from Myrtle Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$46Average$173FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$167Average$367FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$193Average$354FlexibilityNo cancel feeOn-time69%
DeltaCheapest$196Average$303FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$239Average$388FlexibilityNo cancel feeOn-time63%

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