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$79+ Cheap flights from Myrtle Beach (MYR) to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — CHI
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
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Cheap flight deals from Myrtle Beach to Chicago

Cheapest flights from Myrtle Beach to Chicago
Explore the most affordable flight options available from Myrtle Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - MDW
2 stops13h 04mMultiple Airlines
Thu 1/17:44 amMDW - MYR
1 stop15h 15mMultiple Airlines
Deal found 12/23$365
This CheapOair deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:54 amMYR - ORD
1 stop9h 45mSpirit Airlines
Sun 1/47:20 amORD - MYR
1 stop10h 17mSpirit Airlines
Deal found 12/24$453
This Super.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:54 amMYR - ORD
1 stop9h 45mSpirit Airlines
Wed 12/315:00 amORD - MYR
1 stop12h 08mSpirit Airlines
Deal found 12/25$482
This Trip.com deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:54 amMYR - ORD
1 stop9h 45mSpirit Airlines
Fri 1/25:00 amORD - MYR
1 stop12h 08mSpirit Airlines
Deal found 12/24$502
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 pmMYR - MDW
1 stop6h 10mDelta
Thu 1/16:00 amMDW - MYR
1 stop5h 31mDelta
Deal found 12/23$585
This Southwest deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:00 amMYR - MDW
2 stops9h 35mSouthwest
Fri 1/25:25 amMDW - MYR
1 stop5h 40mSouthwest
Deal found 12/24$590
This Southwest deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:45 amMYR - MDW
2 stops6h 50mSouthwest
Thu 1/110:40 amMDW - MYR
2 stops8h 05mSouthwest
Deal found 12/23$595
This Mytrip deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:13 pmMYR - ORD
1 stop14h 18mSpirit Airlines
Tue 12/307:30 amORD - MYR
1 stop9h 38mSpirit Airlines
Deal found 12/24$600
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:12 pmMYR - MDW
1 stop6h 10mDelta
Mon 1/55:31 pmMDW - MYR
1 stop5h 10mDelta
Deal found 12/25$600
This Mytrip deal was found by Cheapflights users on 12/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/287:13 pmMYR - ORD
1 stop14h 18mMultiple Airlines
Tue 12/301:15 pmORD - MYR
3 stops27h 53mMultiple Airlines
Deal found 12/24$620
This United Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:47 pmMYR - ORD
2 stops18h 48mUnited Airlines
Mon 1/56:00 amORD - MYR
1 stop6h 06mUnited Airlines
Deal found 12/25$637
This Southwest deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:25 amMYR - MDW
1 stop5h 55mSouthwest
Wed 12/318:50 amMDW - MYR
1 stop4h 25mSouthwest
Deal found 12/25$656

Find flight deals from Myrtle Beach to Chicago

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Chicago (CHI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$162
(Kiwi.com)

One-way from

$79
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$459

Good round-trip deal

$456 or less

Good one-way deal

$183 or less
Provider with most accurate pricing for Myrtle Beach Intl-Chicago (CHI) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Chicago (CHI) flights.
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From Myrtle Beach Intl to Chicago (CHI)
Search Deals
One-way flight from Myrtle Beach Intl to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($75 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Myrtle Beach Intl to Chicago (CHI).
Search Deals
Price to beat on a one-way flight from Myrtle Beach Intl to Chicago (CHI).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Chicago that are best for you.

Fly from

Myrtle Beach

Fly to

Chicago

Route

Depart

Return

Price

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 1/15

1:07 pm-5:52 pm

1 stop5h 45m

Chicago O'Hare Intl

Wed 2/4

7:20 am-7:10 pm

1 stop10h 50m

$166

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 1/8

1:07 pm-5:52 pm

1 stop5h 45m

Chicago O'Hare Intl

Tue 1/13

6:05 am-12:12 pm

1 stop5h 07m

$175

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Thu 2/26

9:09 am-7:11 pm

1 stop11h 02m

Chicago O'Hare Intl

Mon 3/2

8:16 pm-8:13 am

1 stop10h 57m

$175

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Tue 2/3

1:07 pm-7:41 pm

1 stop7h 34m

Chicago O'Hare Intl

Thu 2/5

7:20 am-7:20 pm

1 stop11h 00m

$176

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Sun 2/1

9:59 pm-9:12 am

1 stop12h 13m

Chicago O'Hare Intl

Sun 2/8

3:00 pm-7:20 pm

1 stop27h 20m

$189

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 1/14

9:59 pm-9:12 am

1 stop12h 13m

Chicago O'Hare Intl

Thu 1/29

8:43 pm-7:20 pm

1 stop21h 37m

$190

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Fri 1/30

10:00 am-10:42 pm

1 stop13h 42m

Chicago O'Hare Intl

Sat 1/31

4:38 pm-2:42 pm

1 stop21h 04m

$192

Myrtle BeachChicago

MYR - ORD

MYRORD

Myrtle Beach Intl

Wed 1/14

10:00 am-9:03 pm

2 stops12h 03m

Chicago O'Hare Intl

Wed 2/4

7:20 am-7:10 pm

1 stop10h 50m

$197

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 1/14

3:00 pm-4:15 pm

Nonstop2h 15m

Chicago Midway

Thu 2/5

3:05 pm-6:00 pm

Nonstop1h 55m

$310

Myrtle BeachChicago

MYR - MDW

MYRMDW

Myrtle Beach Intl

Wed 1/14

11:05 am-6:50 pm

2 stops8h 45m

Chicago Midway

Thu 1/29

11:25 am-2:25 pm

Nonstop2h 00m

$325

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Showing 1-10 of 31 results
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Compare providers for flights from Myrtle Beach to Chicago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Chicago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
PricelinePrice Accuracy1 starTrust Score*3 stars
JustAirTicketPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Myrtle Beach-Chicago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Myrtle Beach-Chicago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Chicago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Myrtle Beach-Chicago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Chicago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Myrtle Beach to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Chicago

What is the cheapest month to book a flight from Myrtle Beach to Chicago?

Currently, June is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $96). Flying from Myrtle Beach to Chicago in February is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to CHI?

Find hourly flight availability from Myrtle Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Myrtle Beach to Chicago in the morning. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the afternoon.

What is the cheapest day to fly from Myrtle Beach to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Myrtle Beach to Chicago. Price data was last updated on December 20, 2025.

Travelers seeking maximum savings on their Myrtle Beach to Chicago flight should consider departing on Friday at noon when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Myrtle Beach to Chicago?

The best insider tips for Myrtle Beach to Chicago flights

AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Myrtle Beach to Chicago trip
Airports
MYR

MYR offers short security lines and a casual atmosphere, making it stress-free for travelers. Check-in desks are available for all airlines.

Read more about MYRBy Daniel Scheffler
MDW

The Orange Line train connects MDW to downtown Chicago in under 30 minutes, offering a convenient and affordable transportation option.

Read more about MDWBy Ramsey Qubein
Our travel experts
Ramsey Qubein

Ramsey Qubein

Expert on MDW

Ramsey Qubein

Ramsey Qubein

An avid traveler and aviation expert who has visited 173 countries, all 50 states and seven continents, Ramsey Qubein flies nearly 400,000 miles a year. As a North Carolina-based freelance journalist for publications including Conde Nast Traveler, Forbes, USA Today and Bloomberg among others, he explores the latest trends in aviation, hospitality, cruises and business.

Read more
Daniel Scheffler

Daniel Scheffler

Expert on MYR

Daniel Scheffler

Daniel Scheffler

Daniel Scheffler is a travel writer, podcaster, and producer. Born in Africa, bred in Europe and now living in America he has traveled to 140 countries (and all 50 U.S. states). Plus he has stayed at over 2500 hotels across the globe. His original shows Everywhere and Without Maps (available on Spotify) showcase his beliefs, travel is about humanity and sharing that beauty. And thus it reminds you that you shouldn’t believe everything you think.

Read more

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated December 26, 2025.
Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Myrtle Beach to Chicago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,258 reviews

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,258 reviews
Southwest
8.0
Very good
4,258 reviews

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,115 reviews
Southwest
8.0
Very good
4,258 reviews

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,064 reviews
Southwest
8.0
Very good
4,258 reviews

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,208 reviews
Southwest
8.0
Very good
4,258 reviews

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Boarding

8.1

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Myrtle Beach to Chicago?

    Myrtle Beach Intl (MYR), located 2.1 mi from the city center, is the airport you fly out of when you book flights from Myrtle Beach to Chicago. 4 airlines have flights from Myrtle Beach Intl to Chicago on a regular basis. Booking flights from Myrtle Beach Intl to Chicago should not be difficult; the airport handles an average of 0 outbound flights to Chicago per day.

  • How long is the flight from Myrtle Beach to Chicago?

    For as low as $310, Spirit Airlines can have you in Chicago from Myrtle Beach in 2h 15m. There are 738 mi between Myrtle Beach and Chicago. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Myrtle Beach to Chicago round-trip?

    Flying on Spirit Airlines is currently your cheapest option to Chicago, with prices starting at $65. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $167 and $178, respectively. You may be able to fly from Myrtle Beach to Chicago for 79% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Myrtle Beach to Chicago one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $50. Users have also found prices from $93 and $100 on Delta and American Airlines, respectively.

  • What are the most reliable airlines from Myrtle Beach to Chicago?

    Consider SkyWest Airlines (100%), Air New Zealand (80%) or United Airlines (50%) when booking your flight. These represent the most reliable airlines when flying from Myrtle Beach to Chicago.

  • What are the cheapest flights from Myrtle Beach to Chicago?

    Looking at all options, your cheapest flight can be booked for $386. While the most popular route (Myrtle Beach Intl - Chicago O'Hare Intl) can be booked for $162 on average, our data indicates $975 when flying from Myrtle Beach to Chicago.

  • Can I find deals for flights from Myrtle Beach to Chicago that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Chicago.

  • Can I find deals for business class flights from Myrtle Beach to Chicago?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Chicago?

    Currently, June is the cheapest month in which you can book a flight from Myrtle Beach to Chicago (average of $96). Flying from Myrtle Beach to Chicago in February is currently the most expensive (average of $228). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Lansing
Merrillville
Hammond
Porter
Benton Harbor

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Alternative routes for Myrtle Beach to Chicago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Myrtle Beach to Chicago

Discover the top 4 airlines that operate flights from Myrtle Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$93Average$196FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$167Average$352FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$193Average$344FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$239Average$388FlexibilityNo cancel feeOn-time63%

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