$466+ Cheap flights from Santa Cruz de la Sierra (VVI) to O'Hare Intl (ORD)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — ORD
Apr 12 — Apr 191
Round-trip
1 adult, Economy
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Find cheap flights from Santa Cruz de la Sierra to O'Hare Intl with Cheapflights
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Cruz de la Sierra to O'Hare Intl
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Best
Last-minute
One-way
Cheapest flights from Santa Cruz de la Sierra to O'Hare IntlExplore the most affordable flight options available from Santa Cruz de la Sierra to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
Explore the most affordable flight options available from Santa Cruz de la Sierra to O'Hare Intl. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 13, 2026.
This Trip.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Sun 5/1711:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/11![Avianca logo]()
$824
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:35 am
VVI
- ORD
3 stops31h 48m
Multiple Airlines
Sun 5/1711:20 pm
ORD
- VVI
1 stop26h 10m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$825
This Copa Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Thu 5/288:02 am
ORD
- VVI
1 stop13h 36m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$840
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Sun 4/1911:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/8![Avianca logo]()
$890
This Faresmojo deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:54 am
VVI
- ORD
1 stop14h 10m
Copa Airlines
Sat 3/288:34 am
ORD
- VVI
1 stop13h 16m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$953
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/193:40 am
VVI
- ORD
1 stop18h 40m
Avianca
Sun 3/2211:20 pm
ORD
- VVI
1 stop26h 15m
Avianca
Deal found 3/9![Avianca logo]()
$977
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:35 am
VVI
- ORD
2 stops32h 15m
Multiple Airlines
Thu 5/2811:20 pm
ORD
- VVI
1 stop26h 10m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$981
This Trip.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/283:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Fri 7/3111:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/12![Avianca logo]()
$994
Best flights from Santa Cruz de la Sierra to O'Hare IntlDiscover carefully curated flight deals from Santa Cruz de la Sierra to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
Discover carefully curated flight deals from Santa Cruz de la Sierra to O'Hare Intl that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 13, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:47 am
VVI
- ORD
1 stop14h 28m
Copa Airlines
Thu 5/288:02 am
ORD
- VVI
1 stop13h 36m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$840
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Sun 4/1911:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/9![Avianca logo]()
$936
This Faresmojo deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:54 am
VVI
- ORD
1 stop14h 10m
Copa Airlines
Sat 3/288:34 am
ORD
- VVI
1 stop13h 16m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$953
Last-minute flights from Santa Cruz de la Sierra to O'Hare IntlDiscover last-minute flight deals from Santa Cruz de la Sierra to O'Hare Intl. Data last updated March 13, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Cruz de la Sierra to O'Hare Intl. Data last updated March 13, 2026 and is based on user searches.
This Avianca deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/193:40 am
VVI
- ORD
1 stop18h 40m
Avianca
Sun 3/2211:20 pm
ORD
- VVI
1 stop26h 15m
Avianca
Deal found 3/9![Avianca logo]()
$977
This Faresmojo deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:54 am
VVI
- ORD
1 stop14h 10m
Copa Airlines
Sat 3/288:34 am
ORD
- VVI
1 stop13h 16m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$953
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Sun 4/1911:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/8![Avianca logo]()
$890
This Trip.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Sun 5/1711:20 pm
ORD
- VVI
1 stop26h 10m
Avianca
Deal found 3/11![Avianca logo]()
$824
This Mytrip deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/253:35 am
VVI
- ORD
3 stops31h 48m
Multiple Airlines
Sun 5/1711:20 pm
ORD
- VVI
1 stop26h 10m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$825
One-way flights from Santa Cruz de la Sierra to O'Hare IntlSearch for one-way flight options from Santa Cruz de la Sierra to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
Search for one-way flight options from Santa Cruz de la Sierra to O'Hare Intl. Find affordable one-way fares based on user searches. Data last updated March 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/163:35 am
VVI
- ORD
2 stops20h 19m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/163:35 am
VVI
- ORD
2 stops36h 39m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$485
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:40 am
VVI
- ORD
2 stops38h 19m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$487
This Avianca deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:40 am
VVI
- ORD
1 stop18h 40m
Avianca
Deal found 3/11![Avianca logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/163:35 am
VVI
- ORD
2 stops15h 40m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$519
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:14 am
VVI
- ORD
2 stops38h 34m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$551
This Avianca deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/193:35 am
VVI
- ORD
1 stop18h 45m
Avianca
Deal found 3/11![Avianca logo]()
$558
Find flight deals from Santa Cruz de la Sierra to O'Hare Intl
Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to O'Hare Intl (ORD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $824 (Trip.com) |
One-way from | $466 (Kiwi.com) |
Popular in | February |
Cheapest in | March |
Average price | $397 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Cruz de la Sierra to O'Hare Intl that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Thu 5/21
11:47 am-1:15 am
1 stop14h 28m
Chicago O'Hare Intl
Thu 5/28
8:02 am-10:38 pm
1 stop13h 36m
$840
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Thu 4/16
3:35 am-9:20 pm
1 stop18h 45m
Chicago O'Hare Intl
Sun 4/19
11:20 pm-2:30 am
1 stop26h 10m
$936
Quickest round-trip
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Tue 3/24
11:54 am-1:04 am
1 stop14h 10m
Chicago O'Hare Intl
Sat 3/28
8:34 am-10:50 pm
1 stop13h 16m
$953
Cheapest one-way
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 3/21
1:14 am-2:48 pm
2 stops38h 34m
$556
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Mon 8/17
11:47 am-1:02 am
1 stop14h 15m
$556
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Fri 6/19
3:35 am-9:20 pm
1 stop18h 45m
$558
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 6/20
7:10 pm-11:47 pm
3 stops53h 37m
$594
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Sat 6/20
11:47 am-8:42 am
2 stops21h 55m
$596
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Tue 6/16
3:35 am-3:14 pm
3 stops36h 39m
$612
Santa Cruz de la SierraChicago
VVI - ORD
VVIORD
Santa Cruz de la Sierra Viru Viru Intl
Thu 3/19
3:40 am-2:48 pm
2 stops36h 08m
$656
Showing 1-10 of 11 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Cruz de la Sierra-Chicago O'Hare Intl Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Cruz de la Sierra to O'Hare Intl
Have a flexible travel schedule? Discover the best time to fly to O'Hare Intl from Santa Cruz de la Sierra with our price prediction graph.
VVI-ORD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing O'Hare Intl
Get insights into the airlines that provide service to O'Hare Intl. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to O'Hare Intl. Reviews last updated March 13, 2026.
Get a feel of what it's like to fly with Copa Airlines from Santa Cruz de la Sierra to Chicago O'Hare Intl Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Entertainment
6.8
Boarding
7.8
Crew
8.1
Food
6.8
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Entertainment
6.8
Boarding
7.8
Crew
8.1
Food
6.8
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Santa Cruz de la Sierra to O'Hare Intl. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Chicago O'Hare Intl Airport?
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Top airline flying from Santa Cruz de la Sierra to O'Hare Intl
Discover the top airline that operate flights from Santa Cruz de la Sierra to O'Hare Intl. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$690 | Average$801 | FlexibilityNo cancel fee | On-time70% |