$111+ Cheap flights from St. Louis to Charleston (STL - CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CHS
Jul 14 — Jul 211
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or October, booked 74 days in advance, depart on a Tuesday or Saturday and return on a Thursday
Cheap flight deals from St. Louis to Charleston
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to CharlestonExplore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 14, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:55 pm
STL
- CHS
1 stop5h 55m
Southwest
Wed 10/148:00 am
CHS
- STL
1 stop6h 50m
Southwest
Deal found 6/9![Southwest logo]()
$221
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:45 pm
STL
- CHS
1 stop4h 00m
Southwest
Tue 8/1110:45 am
CHS
- STL
1 stop8h 10m
Southwest
Deal found 6/13![Southwest logo]()
$237
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Tue 7/148:15 pm
CHS
- STL
1 stop3h 50m
Southwest
Deal found 6/9![Southwest logo]()
$242
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:25 pm
STL
- CHS
1 stop4h 39m
American Airlines
Tue 8/256:00 am
CHS
- STL
1 stop5h 14m
American Airlines
Deal found 6/10![American Airlines logo]()
$243
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- CHS
1 stop7h 06m
United Airlines
Tue 7/1411:31 am
CHS
- STL
1 stop5h 15m
United Airlines
Deal found 6/9![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/208:30 am
STL
- CHS
2 stops7h 55m
Southwest
Tue 8/258:10 am
CHS
- STL
1 stop7h 40m
Southwest
Deal found 6/10![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:00 am
STL
- CHS
1 stop5h 55m
Southwest
Sat 8/156:45 am
CHS
- STL
Nonstop2h 00m
Southwest
Deal found 6/12![Southwest logo]()
$250
This American Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:54 pm
STL
- CHS
1 stop6h 06m
American Airlines
Sat 8/157:42 pm
CHS
- STL
1 stop3h 58m
American Airlines
Deal found 6/13![American Airlines logo]()
$255
Best flights from St. Louis to CharlestonDiscover carefully curated flight deals from St. Louis to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
Discover carefully curated flight deals from St. Louis to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 14, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/72:55 pm
STL
- CHS
1 stop5h 55m
Southwest
Wed 10/148:00 am
CHS
- STL
1 stop6h 50m
Southwest
Deal found 6/9![Southwest logo]()
$221
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:51 am
STL
- CHS
1 stop4h 00m
Delta
Sun 11/157:59 pm
CHS
- STL
1 stop4h 40m
Delta
Deal found 6/13![Delta logo]()
$296
This United Airlines deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:00 am
STL
- CHS
1 stop4h 58m
United Airlines
Wed 8/194:28 pm
CHS
- STL
1 stop6h 32m
United Airlines
Deal found 6/13![United Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/112:30 pm
STL
- CHS
1 stop6h 20m
Southwest
Tue 7/143:00 pm
CHS
- STL
2 stops8h 30m
Southwest
Deal found 6/11![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:00 am
STL
- CHS
1 stop4h 43m
Delta
Thu 7/166:15 am
CHS
- STL
1 stop4h 28m
Delta
Deal found 6/13![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:30 am
STL
- CHS
2 stops7h 55m
Southwest
Fri 9/116:30 pm
CHS
- STL
1 stop4h 35m
Southwest
Deal found 6/10![Southwest logo]()
$314
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/91:22 pm
STL
- CHS
1 stop4h 32m
Delta
Mon 7/135:10 am
CHS
- STL
1 stop4h 09m
Delta
Deal found 6/9![Delta logo]()
$337
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:40 am
STL
- CHS
1 stop5h 40m
Southwest
Fri 11/132:00 pm
CHS
- STL
1 stop9h 25m
Southwest
Deal found 6/9![Southwest logo]()
$323
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Thu 7/164:45 pm
CHS
- STL
Nonstop2h 05m
Southwest
Deal found 6/12![Southwest logo]()
$326
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:25 am
STL
- CHS
2 stops7h 40m
Southwest
Mon 12/146:35 am
CHS
- STL
2 stops8h 15m
Southwest
Deal found 6/11![Southwest logo]()
$333
Last-minute flights from St. Louis to CharlestonDiscover last-minute flight deals from St. Louis to Charleston. Data last updated June 14, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Charleston. Data last updated June 14, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Tue 7/141:50 pm
CHS
- STL
Nonstop2h 10m
Southwest
Deal found 6/9![Southwest logo]()
$237
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- CHS
1 stop7h 06m
United Airlines
Tue 7/1411:31 am
CHS
- STL
1 stop5h 15m
United Airlines
Deal found 6/9![United Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Mon 7/131:55 pm
CHS
- STL
1 stop6h 35m
Southwest
Deal found 6/11![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:00 am
STL
- CHS
1 stop7h 06m
United Airlines
Fri 7/106:00 am
CHS
- STL
1 stop7h 11m
United Airlines
Deal found 6/9![United Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:15 am
STL
- CHS
1 stop4h 55m
Southwest
Fri 7/104:10 pm
CHS
- STL
2 stops7h 40m
Southwest
Deal found 6/9![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/143:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Thu 7/163:15 pm
CHS
- STL
1 stop7h 40m
Southwest
Deal found 6/12![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:57 pm
STL
- CHS
2 stops26h 13m
Multiple Airlines
Sat 7/253:44 pm
CHS
- STL
1 stop9h 15m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$329
One-way flights from St. Louis to CharlestonSearch for one-way flight options from St. Louis to Charleston. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
Search for one-way flight options from St. Louis to Charleston. Find affordable one-way fares based on user searches. Data last updated June 14, 2026.
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:55 am
STL
- CHS
1 stop5h 40m
Southwest
Deal found 6/10![Southwest logo]()
$111
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:15 pm
STL
- CHS
Nonstop2h 00m
Southwest
Deal found 6/10![Southwest logo]()
$119
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/71:22 pm
STL
- CHS
1 stop4h 37m
Delta
Deal found 6/11![Delta logo]()
$124
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:00 am
STL
- CHS
1 stop3h 54m
Delta
Deal found 6/12![Delta logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:57 pm
STL
- CHS
2 stops21h 11m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$130
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:39 pm
STL
- CHS
1 stop4h 05m
Delta
Deal found 6/11![Delta logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:57 pm
STL
- CHS
2 stops26h 13m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:35 am
STL
- CHS
2 stops21h 03m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$137
Find flight deals from St. Louis to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $221 (Southwest) |
One-way from | $111 (Southwest) |
Popular in | July |
Cheapest in | August |
Average price | $394 |
Good round-trip deal | $336 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Wed 10/7
2:55 pm-9:50 pm
1 stop5h 55m
Charleston
Wed 10/14
8:00 am-1:50 pm
1 stop6h 50m
$221
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 11/12
11:51 am-4:51 pm
1 stop4h 00m
Charleston
Sun 11/15
7:59 pm-11:39 pm
1 stop4h 40m
$296
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sat 7/11
2:30 pm-9:50 pm
1 stop6h 20m
Charleston
Tue 7/14
3:00 pm-10:30 pm
2 stops8h 30m
$297
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Fri 9/11
8:30 am-5:25 pm
2 stops7h 55m
Charleston
Fri 9/11
6:30 pm-10:05 pm
1 stop4h 35m
$314
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 8/18
8:00 am-1:58 pm
1 stop4h 58m
Charleston
Wed 8/19
4:28 pm-10:00 pm
1 stop6h 32m
$317
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sun 11/8
6:40 am-1:20 pm
1 stop5h 40m
Charleston
Fri 11/13
2:00 pm-10:25 pm
1 stop9h 25m
$323
Quickest round-trip
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Tue 7/14
3:15 pm-6:15 pm
Nonstop2h 00m
Charleston
Thu 7/16
4:45 pm-5:50 pm
Nonstop2h 05m
$326
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 12/10
8:25 am-5:05 pm
2 stops7h 40m
Charleston
Mon 12/14
6:35 am-1:50 pm
2 stops8h 15m
$333
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Sat 7/11
8:00 am-1:43 pm
1 stop4h 43m
Charleston
Thu 7/16
6:15 am-9:43 am
1 stop4h 28m
$337
St. LouisCharleston
STL - CHS
STLCHS
Lambert-St Louis
Thu 7/9
1:22 pm-6:54 pm
1 stop4h 32m
Charleston
Mon 7/13
5:10 am-8:19 am
1 stop4h 09m
$337
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from St. Louis to Charleston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on St. Louis-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from St. Louis to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.
STL-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Charleston
Prices
More
How far ahead should I book a flight from St. Louis to Charleston?
The price you pay for your flight from St. Louis to Charleston may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from St. Louis to Charleston?
Currently, August is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $313). Flying from St. Louis to Charleston in July is currently the most expensive (average of $414). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to CHS?
Find hourly flight availability from St. Louis to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 14, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Charleston as you normally would.
What’s the top layover airport for flights from St. Louis to Charleston?
Share of 1-stop round-trip flights from St. Louis to Charleston chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Charleston on Cheapflights.
What’s the cheapest layover airport for flights from St. Louis to Charleston?
Average round-trip fare for 1-stop flights from St. Louis to Charleston, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Charlotte (CLT) is the most affordable 1-stop option, with an average round-trip price of $335.
What’s the fastest layover option from St. Louis to Charleston?
Shortest average travel time for 1-stop one-way flights from St. Louis to Charleston, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Charlotte (CLT) have the shortest average one-way travel time for 1-stop routes: 3h 42m.
Which airport typically offers the quickest layover for flights from St. Louis to Charleston?
Average layover duration for 1-stop one-way flights from St. Louis to Charleston, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 0h 55m.
The best insider tips for St. Louis to Charleston flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip
Our travel experts
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated June 14, 2026.
Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Overall
7.9
Crew
8.6
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach
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Top 3 airlines flying from St. Louis to Charleston
Discover the top 3 airlines that operate flights from St. Louis to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$206 | Average$342 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$243 | Average$374 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$245 | Average$397 | FlexibilityNo cancel fee | On-time63% |