Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 09m.

What’s the top layover airport for flights from St. Louis to Charleston?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Charleston on Cheapflights.

What’s the fastest layover option from St. Louis to Charleston?

Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 4h 45m.

What’s the cheapest layover airport for flights from St. Louis to Charleston?

Nashville (BNA) is the most affordable 1-stop option, with an average round-trip price of $326.

How popular is this St. Louis to Charleston flight route?

Flights from Lambert-St Louis to Charleston have been viewed 2 times in the past calendar month.

How long is the flight from St. Louis to Charleston?

A quick flight from St. Louis to Charleston can take about 5h 54m. Delta provides one of the quickest options available for as low as $333. Airlines will cover a distance of 705 mi.

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

Cheapflights users have booked flights from St. Louis to Charleston round-trip from $206. Other airlines that can offer you cheap pricing are American Airlines, from $246, and Southwest, from $271. These flights start at 46% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from St. Louis to Charleston one-way?

The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from St. Louis to Charleston for a low price.

In terms of precipitation, rainfall in Charleston ranges from 2.4 - 7.2 inches per month. August is typically the wettest month, when rainfall can reach 7.2 in. November is typically the driest time to visit Charleston when rainfall is around 2.4 in.

If weather is an important factor for your trip to Charleston, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What are the most popular airlines that fly from St. Louis to Charleston?

When booking a flight from St. Louis to Charleston, you may want to consider flying on Southwest, American Airlines or Delta as they are the most popular for this route.

What is the cheapest time of day to fly from STL to CHS?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from St. Louis to Charleston as you normally would.

Most accurate provider : When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Charleston?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.

Can I find deals for business class flights from St. Louis to Charleston?

Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$79+ Flights from St. Louis to Charleston

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or November, booked 49 days in advance, depart on a Monday or Sunday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 1, 2026.

Wed 12/315:13 pmSTL - CHS

1 stop5h 45mDelta

Tue 1/611:39 amCHS - STL

1 stop5h 58mDelta

Deal found 12/31

$351

Wed 12/316:00 pmSTL - CHS

1 stop5h 45mAmerican Airlines

Tue 1/612:29 pmCHS - STL

2 stops6h 47mAmerican Airlines

Deal found 12/31

$356

Wed 12/316:00 pmSTL - CHS

1 stop5h 45mAmerican Airlines

Sat 1/109:13 amCHS - STL

1 stop4h 56mAmerican Airlines

Deal found 12/30

$373

Wed 12/316:00 pmSTL - CHS

1 stop5h 45mAmerican Airlines

Fri 1/23:38 pmCHS - STL

1 stop8h 18mAmerican Airlines

Deal found 12/29

$404

Wed 12/3111:05 amSTL - CHS

2 stops11h 39mUnited Airlines

Fri 1/26:05 amCHS - STL

1 stop7h 22mUnited Airlines

Deal found 12/29

$409

Wed 12/311:05 pmSTL - CHS

1 stop4h 59mUnited Airlines

Tue 1/62:58 pmCHS - STL

2 stops9h 00mUnited Airlines

Deal found 12/30

$426

Wed 12/312:30 pmSTL - CHS

1 stop5h 05mSouthwest

Sun 1/44:30 pmCHS - STL

2 stops8h 35mSouthwest

Deal found 12/30

$504

Wed 12/3110:15 amSTL - CHS

2 stops8h 40mSouthwest

Fri 1/211:15 amCHS - STL

2 stops7h 15mSouthwest

Deal found 12/29

$658

Wed 12/3110:15 amSTL - CHS

2 stops8h 40mSouthwest

Sat 1/102:00 pmCHS - STL

2 stops7h 55mSouthwest

Deal found 12/30

$665

Best flights from St. Louis to Charleston
Discover carefully curated flight deals from St. Louis to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 1, 2026.

Wed 2/183:49 pmSTL - CHS

1 stop15h 49mMultiple Airlines

Tue 2/245:00 pmCHS - STL

2 stops30h 27mMultiple Airlines

Deal found 12/31

$189

Tue 2/175:00 pmSTL - CHS

1 stop5h 54mDelta

Wed 2/2510:30 amCHS - STL

1 stop5h 17mDelta

Deal found 12/30

$333

Sat 1/178:30 amSTL - CHS

1 stop5h 18mUnited Airlines

Sat 1/2410:30 amCHS - STL

1 stop4h 58mUnited Airlines

Deal found 12/31

$344

Thu 2/58:20 amSTL - CHS

2 stops11h 30mSouthwest

Mon 2/97:35 amCHS - STL

2 stops9h 20mSouthwest

Deal found 12/30

$347

Wed 2/183:49 pmSTL - CHS

1 stop15h 49mMultiple Airlines

Fri 2/205:00 pmCHS - STL

2 stops16h 56mMultiple Airlines

Deal found 12/31

$196

Sun 2/153:49 pmSTL - CHS

1 stop15h 54mMultiple Airlines

Fri 2/203:21 pmCHS - STL

1 stop10h 06mMultiple Airlines

Deal found 12/30

$231

Tue 2/171:13 pmSTL - CHS

1 stop6h 32mDelta

Tue 2/245:00 pmCHS - STL

1 stop3h 39mDelta

Deal found 12/30

$333

Mon 2/239:10 amSTL - CHS

2 stops10h 40mSouthwest

Thu 2/266:25 amCHS - STL

2 stops8h 05mSouthwest

Deal found 12/30

$347

Sat 2/141:20 pmSTL - CHS

1 stop6h 25mDelta

Wed 2/255:27 amCHS - STL

1 stop4h 39mDelta

Deal found 12/30

$345

Sat 2/143:49 pmSTL - CHS

1 stop15h 49mMultiple Airlines

Sun 2/223:01 pmCHS - STL

1 stop9h 58mMultiple Airlines

Deal found 12/31

$338

Thu 2/197:10 amSTL - CHS

1 stop5h 50mDelta

Wed 2/2510:30 amCHS - STL

1 stop5h 17mDelta

Deal found 12/30

$345

Sat 1/175:11 pmSTL - CHS

1 stop14h 27mMultiple Airlines

Sat 1/246:35 pmCHS - STL

2 stops37h 16mMultiple Airlines

Deal found 12/31

$338

Last-minute flights from St. Louis to Charleston
Discover last-minute flight deals from St. Louis to Charleston. Data last updated January 1, 2026 and is based on user searches.

Sat 1/103:54 pmSTL - CHS

1 stop4h 17mAmerican Airlines

Tue 1/137:32 amCHS - STL

1 stop8h 11mAmerican Airlines

Deal found 12/29

$305

Sun 1/113:43 pmSTL - CHS

2 stops24h 53mMultiple Airlines

Tue 1/133:01 pmCHS - STL

1 stop8h 33mMultiple Airlines

Deal found 12/29

$304

Mon 1/125:11 pmSTL - CHS

1 stop14h 27mMultiple Airlines

Tue 1/133:01 pmCHS - STL

1 stop8h 33mMultiple Airlines

Deal found 12/29

$174

Sat 1/173:43 pmSTL - CHS

2 stops15h 55mMultiple Airlines

Tue 1/203:01 pmCHS - STL

1 stop9h 32mMultiple Airlines

Deal found 12/31

$301

Sat 1/249:54 amSTL - CHS

1 stop4h 55mAmerican Airlines

Sat 1/313:46 pmCHS - STL

1 stop7h 58mAmerican Airlines

Deal found 12/31

$249

One-way flights from St. Louis to Charleston
Search for one-way flight options from St. Louis to Charleston. Find affordable one-way fares based on user searches. Data last updated January 1, 2026.

Wed 1/285:42 pmSTL - CHS

1 stop13h 56mMultiple Airlines

Deal found 12/29

$79

Wed 2/253:49 pmSTL - CHS

1 stop15h 49mMultiple Airlines

Deal found 12/31

$90

Fri 1/305:42 pmSTL - CHS

2 stops22h 54mMultiple Airlines

Deal found 12/31

$107

Sun 3/13:49 pmSTL - CHS

2 stops24h 51mMultiple Airlines

Deal found 12/31

$108

Mon 3/23:49 pmSTL - CHS

2 stops23h 16mMultiple Airlines

Deal found 12/31

$114

Sat 2/283:49 pmSTL - CHS

2 stops24h 51mMultiple Airlines

Deal found 12/30

$116

Sat 2/2810:43 amSTL - CHS

1 stop5h 55mAmerican Airlines

Deal found 12/31

$125

Find flight deals from St. Louis to Charleston

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$174 (Kiwi.com)
One-way from	$79 (Kiwi.com)
Popular in	March
Cheapest in	August
Average price	$398

Provider with most accurate pricing for Lambert-St Louis-Charleston flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Charleston flights.

Search Deals

From Lambert-St Louis to Charleston

Search Deals

One-way flight from Lambert-St Louis to Charleston

Search Deals

Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in January 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Wed 2/18

3:49 pm-8:38 am

1 stop15h 49m

Charleston

Tue 2/24

5:00 pm-10:27 pm

2 stops30h 27m

$189

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Wed 2/18

3:49 pm-8:38 am

1 stop15h 49m

Charleston

Fri 2/20

5:00 pm-8:56 am

2 stops16h 56m

$196

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sun 2/15

3:49 pm-8:43 am

1 stop15h 54m

Charleston

Fri 2/20

3:21 pm-12:27 am

1 stop10h 06m

$231

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 2/17

5:00 pm-11:54 pm

1 stop5h 54m

Charleston

Wed 2/25

10:30 am-2:47 pm

1 stop5h 17m

$333

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 2/17

1:13 pm-8:45 pm

1 stop6h 32m

Charleston

Tue 2/24

5:00 pm-7:39 pm

1 stop3h 39m

$333

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 2/14

3:49 pm-8:38 am

1 stop15h 49m

Charleston

Sun 2/22

3:01 pm-11:59 pm

1 stop9h 58m

$338

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 1/17

5:11 pm-8:38 am

1 stop14h 27m

Charleston

Sat 1/24

6:35 pm-6:51 am

2 stops37h 16m

$338

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 1/17

8:30 am-2:48 pm

1 stop5h 18m

Charleston

Sat 1/24

10:30 am-2:28 pm

1 stop4h 58m

$344

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 2/14

1:20 pm-8:45 pm

1 stop6h 25m

Charleston

Wed 2/25

5:27 am-9:06 am

1 stop4h 39m

$345

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 2/19

7:10 am-2:00 pm

1 stop5h 50m

Charleston

Wed 2/25

10:30 am-2:47 pm

1 stop5h 17m

$345

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 20 results

Compare providers for flights from St. Louis to Charleston

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in January.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

Prices

How far ahead should I book a flight from St. Louis to Charleston?

The price you pay for your flight from St. Louis to Charleston may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Charleston?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

The best insider tips for St. Louis to Charleston flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

Expect security screening at STL to take 5-10 minutes during off-peak times. Check wait times online before heading to the airport.

CHS

For a quick ride to downtown Charleston, use rideshare services from CHS. They're convenient and offer in-app tracking.

Our travel experts

Taryn White

Expert on STL

Ramsey Qubein

Expert on CHS

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,253 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,013 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,069 reviews

Southwest

8.0

Very good

4,253 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How popular is this St. Louis to Charleston flight route?
Flights from Lambert-St Louis to Charleston have been viewed 2 times in the past calendar month.
How long is the flight from St. Louis to Charleston?
A quick flight from St. Louis to Charleston can take about 5h 54m. Delta provides one of the quickest options available for as low as $333. Airlines will cover a distance of 705 mi.
What are the cheapest airlines flying from St. Louis to Charleston round-trip?
Cheapflights users have booked flights from St. Louis to Charleston round-trip from $206. Other airlines that can offer you cheap pricing are American Airlines, from $246, and Southwest, from $271. These flights start at 46% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from St. Louis to Charleston one-way?
The cheapest airline one-way is Delta, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from American Airlines and Southwest, as they are both options that can get you from St. Louis to Charleston for a low price.
Can I find deals for flights from St. Louis to Charleston that include hotel bookings?
Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Charleston?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.
Can I find deals for business class flights from St. Louis to Charleston?
Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Charleston?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from St. Louis to Charleston

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$206	Average$378	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$246	Average$385	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$271	Average$404	FlexibilityNo cancel fee	On-time63%

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$79+ Cheap flights from St. Louis to Charleston (STL - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Charleston with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or November, booked 49 days in advance, depart on a Monday or Sunday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to CharlestonExplore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 1, 2026.

Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 1, 2026.

Find flight deals from St. Louis to Charleston

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Compare providers for flights from St. Louis to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in January.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

How far ahead should I book a flight from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

What’s the top layover airport for flights from St. Louis to Charleston?

What’s the cheapest layover airport for flights from St. Louis to Charleston?

What’s the fastest layover option from St. Louis to Charleston?

Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

The best insider tips for St. Louis to Charleston flights

AI-powered summary based on content written by travel experts. AI can make mistakes.

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

CHS

Our travel experts

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this St. Louis to Charleston flight route?

How long is the flight from St. Louis to Charleston?

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

What are the cheapest airlines to fly from St. Louis to Charleston one-way?

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

How can I find direct flights from St. Louis to Charleston?

Can I find deals for business class flights from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

Traveling to a place near Charleston?

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Alternative routes for St. Louis to Charleston

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Top 3 airlines flying from St. Louis to Charleston

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Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 1, 2026.