What’s the fastest layover option from St. Louis to Charleston?

Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 4h 45m.

What’s the cheapest layover airport for flights from St. Louis to Charleston?

Nashville (BNA) is the most affordable 1-stop option, with an average round-trip price of $326.

What’s the top layover airport for flights from St. Louis to Charleston?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Charleston on Cheapflights.

Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 09m.

How popular is this St. Louis to Charleston flight route?

Flights from Lambert-St Louis to Charleston have been viewed 6 times in the past calendar month.

How long is the flight from St. Louis to Charleston?

A quick flight from St. Louis to Charleston can take about 4h 45m. United Airlines provides one of the quickest options available for as low as $307. Airlines will cover a distance of 705 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

Cheapflights users have booked flights from St. Louis to Charleston round-trip from $208. Other airlines that can offer you cheap pricing are American Airlines, from $275, and Southwest, from $286. These flights start at 46% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Charleston ranges from 2.4 - 7.2 inches per month. August is typically the wettest month, when rainfall can reach 7.2 in. November is typically the driest time to visit Charleston when rainfall is around 2.4 in.

If weather is an important factor for your trip to Charleston, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What are the most popular airlines that fly from St. Louis to Charleston?

When booking a flight from St. Louis to Charleston, you may want to consider flying on American Airlines, Southwest or Delta as they are the most popular for this route.

Most accurate provider : When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Charleston?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.

Can I find deals for business class flights from St. Louis to Charleston?

Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$78+ Flights from St. Louis to Charleston

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from St. Louis to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or October, booked 49 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$208 (Kiwi.com)
One-way from	$78 (Kiwi.com)
Popular in	May
Cheapest in	August
Average price	$353

Provider with most accurate pricing for Lambert-St Louis-Charleston flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Charleston flights.

Search Deals

From Lambert-St Louis to Charleston

Search Deals

One-way flight from Lambert-St Louis to Charleston

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($16 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Find flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Thu 12/112:47 pmSTL - CHS

1 stop29h 07mMultiple Airlines

Mon 12/153:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 10/27

$264

Sun 12/2810:57 amSTL - CHS

2 stops33h 26mMultiple Airlines

Thu 1/12:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 10/27

$270

Mon 12/158:00 amSTL - CHS

1 stop4h 55mUnited Airlines

Wed 12/1711:33 amCHS - STL

1 stop5h 07mUnited Airlines

Deal found 10/28

$307

Mon 11/1710:25 amSTL - CHS

1 stop21h 12mMultiple Airlines

Mon 11/246:13 pmCHS - STL

2 stops21h 16mMultiple Airlines

Deal found 10/27

$311

Mon 12/151:20 pmSTL - CHS

2 stops6h 55mSouthwest

Wed 12/1710:35 amCHS - STL

1 stop6h 15mSouthwest

Deal found 10/28

$317

Thu 12/118:15 amSTL - CHS

2 stops7h 50mSouthwest

Mon 12/156:00 amCHS - STL

2 stops7h 35mSouthwest

Deal found 10/27

$335

Thu 11/1311:07 amSTL - CHS

2 stops19h 49mMultiple Airlines

Sun 11/162:59 pmCHS - STL

1 stop23h 18mMultiple Airlines

Deal found 10/27

$349

Tue 12/301:22 pmSTL - CHS

1 stop6h 17mDelta

Fri 1/28:35 amCHS - STL

1 stop4h 46mDelta

Deal found 10/26

$350

Sun 11/26:21 pmSTL - CHS

2 stops21h 45mMultiple Airlines

Sun 11/92:59 pmCHS - STL

1 stop19h 41mMultiple Airlines

Deal found 10/27

$353

Best flights from St. Louis to Charleston
Discover carefully curated flight deals from St. Louis to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 29, 2025.

Thu 12/112:47 pmSTL - CHS

1 stop29h 07mMultiple Airlines

Mon 12/153:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 10/27

$264

Mon 12/158:00 amSTL - CHS

1 stop4h 55mUnited Airlines

Wed 12/1711:33 amCHS - STL

1 stop5h 07mUnited Airlines

Deal found 10/28

$307

Mon 12/156:00 amSTL - CHS

1 stop4h 45mDelta

Wed 12/1710:40 amCHS - STL

1 stop6h 41mDelta

Deal found 10/28

$307

Mon 12/151:20 pmSTL - CHS

2 stops6h 55mSouthwest

Wed 12/177:00 amCHS - STL

2 stops7h 50mSouthwest

Deal found 10/28

$327

Sun 12/2810:57 amSTL - CHS

2 stops33h 26mMultiple Airlines

Thu 1/12:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 10/27

$270

Thu 12/118:15 amSTL - CHS

2 stops7h 50mSouthwest

Mon 12/156:00 amCHS - STL

2 stops7h 35mSouthwest

Deal found 10/27

$335

Tue 12/301:22 pmSTL - CHS

1 stop6h 17mDelta

Fri 1/28:35 amCHS - STL

1 stop4h 46mDelta

Deal found 10/26

$350

Mon 11/172:12 pmSTL - CHS

1 stop17h 25mMultiple Airlines

Mon 11/243:33 pmCHS - STL

1 stop9h 24mMultiple Airlines

Deal found 10/27

$340

Tue 12/22:25 pmSTL - CHS

1 stop5h 10mSouthwest

Sat 12/61:25 pmCHS - STL

1 stop7h 05mSouthwest

Deal found 10/27

$363

Sun 11/26:21 pmSTL - CHS

2 stops21h 45mMultiple Airlines

Sun 11/92:59 pmCHS - STL

1 stop19h 41mMultiple Airlines

Deal found 10/27

$353

Thu 1/812:20 pmSTL - CHS

3 stops27h 25mMultiple Airlines

Sun 1/115:40 pmCHS - STL

3 stops25h 56mMultiple Airlines

Deal found 10/28

$361

Last-minute flights from St. Louis to Charleston
Discover last-minute flight deals from St. Louis to Charleston. Data last updated October 29, 2025 and is based on user searches.

Sun 11/26:21 pmSTL - CHS

2 stops21h 45mMultiple Airlines

Sun 11/92:59 pmCHS - STL

1 stop19h 41mMultiple Airlines

Deal found 10/27

$353

Thu 11/1311:07 amSTL - CHS

2 stops19h 49mMultiple Airlines

Sun 11/162:59 pmCHS - STL

1 stop23h 18mMultiple Airlines

Deal found 10/27

$349

Mon 11/1710:25 amSTL - CHS

1 stop21h 12mMultiple Airlines

Mon 11/246:13 pmCHS - STL

2 stops21h 16mMultiple Airlines

Deal found 10/27

$311

Fri 11/216:02 amSTL - CHS

1 stop6h 21mAmerican Airlines

Tue 11/257:00 amCHS - STL

1 stop6h 37mAmerican Airlines

Deal found 10/28

$415

Fri 11/214:13 pmSTL - CHS

2 stops14h 13mMultiple Airlines

Tue 11/252:59 pmCHS - STL

1 stop19h 30mMultiple Airlines

Deal found 10/28

$416

Tue 11/253:14 pmSTL - CHS

2 stops15h 12mMultiple Airlines

Fri 11/286:50 amCHS - STL

1 stop27h 07mMultiple Airlines

Deal found 10/28

$375

Tue 11/255:17 amSTL - CHS

1 stop5h 38mAmerican Airlines

Fri 11/285:10 amCHS - STL

1 stop4h 17mAmerican Airlines

Deal found 10/28

$404

Fri 11/285:05 pmSTL - CHS

1 stop4h 30mSouthwest

Mon 12/18:00 pmCHS - STL

1 stop5h 05mSouthwest

Deal found 10/27

$393

One-way flights from St. Louis to Charleston
Search for one-way flight options from St. Louis to Charleston. Find affordable one-way fares based on user searches. Data last updated October 29, 2025.

Wed 1/75:11 pmSTL - CHS

1 stop14h 22mMultiple Airlines

Deal found 10/27

$78

Mon 1/510:40 amSTL - CHS

1 stop20h 57mMultiple Airlines

Deal found 10/28

$79

Thu 11/2710:53 amSTL - CHS

1 stop10h 12mSpirit Airlines

Deal found 10/27

$80

Sun 1/115:11 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 10/27

$83

Mon 1/195:06 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 10/27

$85

Sun 12/72:47 pmSTL - CHS

1 stop5h 07mSpirit Airlines

Deal found 10/27

$95

Sun 1/255:11 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 10/28

$96

Thu 1/2212:20 pmSTL - CHS

1 stop21h 25mSpirit Airlines

Deal found 10/27

$98

Wed 12/37:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Deal found 10/28

$106

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Deal found 10/27

$108

Thu 12/412:04 pmSTL - CHS

2 stops21h 56mMultiple Airlines

Deal found 10/27

$112

Thu 1/810:42 amSTL - CHS

2 stops29h 03mMultiple Airlines

Deal found 10/27

$113

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 12/11

2:47 pm-8:54 pm

1 stop29h 07m

Charleston

Mon 12/15

3:33 pm-10:33 pm

1 stop8h 00m

$264

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sun 12/28

10:57 am-9:23 pm

2 stops33h 26m

Charleston

Thu 1/1

2:59 pm-10:33 pm

1 stop8h 34m

$270

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/15

8:00 am-1:55 pm

1 stop4h 55m

Charleston

Wed 12/17

11:33 am-3:40 pm

1 stop5h 07m

$307

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/15

6:00 am-11:45 am

1 stop4h 45m

Charleston

Wed 12/17

10:40 am-4:21 pm

1 stop6h 41m

$307

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/15

1:20 pm-9:15 pm

2 stops6h 55m

Charleston

Wed 12/17

7:00 am-1:50 pm

2 stops7h 50m

$327

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 12/11

8:15 am-5:05 pm

2 stops7h 50m

Charleston

Mon 12/15

6:00 am-12:35 pm

2 stops7h 35m

$335

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 11/17

2:12 pm-8:37 am

1 stop17h 25m

Charleston

Mon 11/24

3:33 pm-11:57 pm

1 stop9h 24m

$340

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 12/30

1:22 pm-8:39 pm

1 stop6h 17m

Charleston

Fri 1/2

8:35 am-12:21 pm

1 stop4h 46m

$350

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sun 11/2

6:21 pm-5:06 pm

2 stops21h 45m

Charleston

Sun 11/9

2:59 pm-9:40 am

1 stop19h 41m

$353

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 1/8

12:20 pm-4:45 pm

3 stops27h 25m

Charleston

Sun 1/11

5:40 pm-6:36 pm

3 stops25h 56m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 21 results

Compare providers for flights from St. Louis to Charleston

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in October.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

Prices

How far ahead should I book a flight from St. Louis to Charleston?

The price you pay for your flight from St. Louis to Charleston may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Charleston?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to CHS?

One of the essential ways to save on airfare from St. Louis to Charleston is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.

What is the cheapest day to fly from St. Louis to Charleston?

Travelers seeking maximum savings on their St. Louis to Charleston flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for St. Louis to Charleston flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

Expect security screening at STL to take 5-10 minutes during off-peak times. Check wait times online before heading to the airport.

CHS

For a quick ride to downtown Charleston, use rideshare services from CHS. They're convenient and offer in-app tracking.

Our travel experts

Taryn White

Expert on STL

Ramsey Qubein

Expert on CHS

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,241 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

7.9

Good

7,992 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,032 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How popular is this St. Louis to Charleston flight route?
Flights from Lambert-St Louis to Charleston have been viewed 6 times in the past calendar month.
How long is the flight from St. Louis to Charleston?
A quick flight from St. Louis to Charleston can take about 4h 45m. United Airlines provides one of the quickest options available for as low as $307. Airlines will cover a distance of 705 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from St. Louis to Charleston round-trip?
Cheapflights users have booked flights from St. Louis to Charleston round-trip from $208. Other airlines that can offer you cheap pricing are American Airlines, from $275, and Southwest, from $286. These flights start at 46% lower than the current average price 3 months from now.
Can I find deals for flights from St. Louis to Charleston that include hotel bookings?
Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Charleston?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.
Can I find deals for business class flights from St. Louis to Charleston?
Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Charleston?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

North Charleston

Summerville

Walterboro

Isle of Palms

Santee

Mount Pleasant

Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for St. Louis to Charleston

St. Louis to Charlotte flights

Kansas City to Charleston flights

Kansas City to Savannah flights

St. Louis to Savannah flights

Kansas City to Charlotte flights

St. Louis to Myrtle Beach flights

Springfield to Charlotte flights

Kansas City to Myrtle Beach flights

Springfield to Columbia flights

Springfield to Charleston flights

St. Louis to Columbia flights

Springfield to Savannah flights

Kansas City to Augusta flights

St. Louis to Greenville flights

Kansas City to Columbia flights

St. Louis to Augusta flights

Kansas City to Greenville flights

Kansas City to Hilton Head Island flights

Springfield to Greenville flights

Columbia to Charleston flights

Springfield to Myrtle Beach flights

St. Louis to Hilton Head Island flights

Columbia to Charlotte flights

Joplin to Charlotte flights

Columbia to Myrtle Beach flights

Joplin to Savannah flights

Springfield to Hilton Head Island flights

Springfield to Augusta flights

St. Louis to Florence flights

Joplin to Charleston flights

Joplin to Augusta flights

Joplin to Columbia flights

Columbia to Hilton Head Island flights

Cape Girardeau to Charlotte flights

Kansas City to Florence flights

Joplin to Hilton Head Island flights

Other flights to Charleston

Complete your trip

Charleston car rentals

Charleston Airport car rentals

Savannah/Hilton Head Airport car rentals

Myrtle Beach Intl Airport car rentals

Hilton Head Island Airport car rentals

Florence Airport car rentals

Myrtle Beach car rentals

Columbia car rentals

Greenville car rentals

Florence car rentals

Hilton Head Island car rentals

Top 3 airlines flying from St. Louis to Charleston

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$208	Average$388	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$275	Average$379	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$286	Average$404	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$78+ Cheap flights from St. Louis to Charleston (STL - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Charleston with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or October, booked 49 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to CharlestonExplore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Compare providers for flights from St. Louis to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in October.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

How far ahead should I book a flight from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

What is the cheapest time of day to fly from STL to CHS?

What is the cheapest day to fly from St. Louis to Charleston?

What’s the top layover airport for flights from St. Louis to Charleston?

What’s the fastest layover option from St. Louis to Charleston?

What’s the fastest layover option from St. Louis to Charleston?

Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

The best insider tips for St. Louis to Charleston flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

CHS

Our travel experts

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this St. Louis to Charleston flight route?

How long is the flight from St. Louis to Charleston?

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

How can I find direct flights from St. Louis to Charleston?

Can I find deals for business class flights from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

Traveling to a place near Charleston?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for St. Louis to Charleston

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from St. Louis to Charleston

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.