HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Charleston

$300+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
May 8 — May 151
Fri 5/8
Fri 5/15
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 8, 2026.

This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:15 pm
PTY
-
CHS
1 stop7h 41m
Delta
Tue 6/167:20 am
CHS
-
PTY
1 stop6h 49m
Delta
Deal found 4/3$476
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:55 am
PTY
-
CHS
1 stop13h 20m
United Airlines
Wed 6/37:47 pm
CHS
-
PTY
2 stops24h 44m
United Airlines
Deal found 4/5$495
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/271:14 pm
PTY
-
CHS
1 stop9h 45m
American Airlines
Wed 6/37:34 pm
CHS
-
PTY
1 stop17h 40m
American Airlines
Deal found 4/5$500
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:49 pm
PTY
-
CHS
1 stop9h 35m
American Airlines
Tue 5/126:00 am
CHS
-
PTY
1 stop7h 46m
American Airlines
Deal found 4/7$504
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/53:30 pm
PTY
-
CHS
2 stops17h 38m
United Airlines
Mon 6/156:50 am
CHS
-
PTY
1 stop8h 24m
United Airlines
Deal found 4/3$515
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:30 pm
PTY
-
CHS
2 stops17h 38m
United Airlines
Tue 6/166:50 am
CHS
-
PTY
1 stop12h 47m
United Airlines
Deal found 4/7$517
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2310:00 am
PTY
-
CHS
1 stop11h 13m
United Airlines
Sat 9/266:30 am
CHS
-
PTY
1 stop8h 44m
United Airlines
Deal found 4/3$524

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$476
(Delta)

One-way from

$300
(United Airlines)

Popular in

March

Cheapest in

December

Average price

$537
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
Search Deals
From Panama City Tocumen Intl to Charleston
Search Deals
One-way flight from Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 8, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

2:15 pm-10:56 pm

1 stop7h 41m

Charleston

Tue 6/16

7:20 am-1:09 pm

1 stop6h 49m

$476

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

3:30 pm-10:15 pm

1 stop29h 45m

Charleston

Wed 6/3

11:18 am-7:31 pm

1 stop9h 13m

$495

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

3:30 pm-10:08 am

2 stops17h 38m

Charleston

Tue 6/16

6:50 am-6:37 pm

1 stop12h 47m

$495

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

1:14 pm-11:59 pm

1 stop9h 45m

Charleston

Wed 6/3

4:13 pm-12:14 pm

2 stops21h 01m

$505

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Tue 5/5

1:49 pm-12:24 am

1 stop9h 35m

Charleston

Tue 5/12

7:39 pm-12:46 pm

2 stops18h 07m

$509

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/2

10:55 pm-9:10 am

1 stop9h 15m

Charleston

Tue 5/12

5:07 pm-2:14 pm

1 stop22h 07m

$515
Cheapest one-way

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 5/23

3:30 pm-10:15 pm

1 stop29h 45m

$300

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 4/15

10:10 am-8:38 am

2 stops21h 28m

$368
Quickest one-way

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 4/15

7:55 am-9:59 pm

1 stop13h 04m

$399

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/6

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest month to book a flight from Panama City to Charleston?

Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $148). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $476, Delta can have you in Charleston from Panama City in 7h 41m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $148). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Charlotte flights
Panama City to Greenville flights
Panama City to Myrtle Beach flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.