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$424+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Feb 23 — Mar 21
Mon 2/23
Mon 3/2
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 24, 2026.

This United Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/110:00 am
PTY
-
CHS
1 stop11h 12m
United Airlines
Tue 6/167:00 am
CHS
-
PTY
1 stop10h 12m
United Airlines
Deal found 1/23$424
This American Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:10 pm
PTY
-
CHS
2 stops23h 31m
American Airlines
Tue 6/166:10 pm
CHS
-
PTY
2 stops19h 00m
American Airlines
Deal found 1/23$432
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/81:40 pm
PTY
-
CHS
2 stops17h 53m
American Airlines
Sun 3/156:45 pm
CHS
-
PTY
2 stops18h 55m
American Airlines
Deal found 1/22$456
This KAYAK deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/17:55 am
PTY
-
CHS
1 stop13h 17m
Copa Airlines
Tue 6/167:00 am
CHS
-
PTY
1 stop10h 12m
Copa Airlines
Deal found 1/23$478
This United Airlines deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1911:35 am
PTY
-
CHS
1 stop28h 38m
United Airlines
Tue 2/2411:15 am
CHS
-
PTY
1 stop8h 47m
United Airlines
Deal found 1/23$498
This Faresmojo deal was found by Cheapflights users on 1/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/272:28 pm
PTY
-
CHS
1 stop8h 48m
JetBlue
Sun 3/297:58 pm
CHS
-
PTY
1 stop18h 05m
JetBlue
Deal found 1/23$518
This American Airlines deal was found by Cheapflights users on 1/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/124:05 pm
PTY
-
CHS
1 stop7h 54m
American Airlines
Sun 3/18:25 pm
CHS
-
PTY
2 stops17h 15m
American Airlines
Deal found 1/22$569

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 24, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$424
(United Airlines)

Popular in

March

Cheapest in

December

Average price

$615
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
Search Deals
From Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($41 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 24, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

10:00 am-10:12 pm

1 stop11h 12m

Charleston

Tue 6/16

7:00 am-4:12 pm

1 stop10h 12m

$424

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

1:10 pm-1:41 pm

2 stops23h 31m

Charleston

Tue 6/16

6:10 pm-12:10 pm

2 stops19h 00m

$432

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 3/8

1:40 pm-8:33 am

2 stops17h 53m

Charleston

Sun 3/15

6:45 pm-12:40 pm

2 stops18h 55m

$456

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 2/19

11:35 am-4:13 pm

1 stop28h 38m

Charleston

Tue 2/24

11:15 am-8:02 pm

1 stop8h 47m

$498

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 3/27

2:28 pm-12:16 am

1 stop8h 48m

Charleston

Sun 3/29

7:58 pm-1:03 pm

1 stop18h 05m

$518

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 2/12

4:05 pm-11:59 pm

1 stop7h 54m

Charleston

Sun 3/1

8:25 pm-1:40 pm

2 stops17h 15m

$569

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/23

  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest month to book a flight from Panama City to Charleston?

Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $148). Flying from Panama City to Charleston in November is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $424, United Airlines can have you in Charleston from Panama City in 11h 12m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $148). Flying from Panama City to Charleston in November is currently the most expensive (average of $530). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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