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$413+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$413
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$426
From Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($167 potential increase over avg. RT price).
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Cheapest flight prices on average. 8% potential price decrease ($42 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:15 pmPTY - CHS
1 stop7h 44mAmerican Airlines
Tue 11/189:22 amCHS - PTY
1 stop28h 27mAmerican Airlines
Deal found 9/15$413
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:30 pmPTY - CHS
1 stop24h 14mUnited Airlines
Sat 11/16:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Deal found 9/15$474
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/303:15 pmPTY - CHS
2 stops19h 20mAmerican Airlines
Thu 11/66:40 pmCHS - PTY
2 stops19h 09mAmerican Airlines
Deal found 9/14$531
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/173:15 pmPTY - CHS
1 stop7h 44mAmerican Airlines
Sat 11/14:30 pmCHS - PTY
2 stops22h 19mAmerican Airlines
Deal found 9/14$605
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:56 pmPTY - CHS
1 stop15h 51mAmerican Airlines
Sat 1/108:39 pmCHS - PTY
2 stops18h 56mAmerican Airlines
Deal found 9/14$611
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:55 pmPTY - CHS
1 stop9h 15mUnited Airlines
Sat 1/104:55 pmCHS - PTY
1 stop21h 50mUnited Airlines
Deal found 9/14$654
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/292:55 amPTY - CHS
3 stops38h 18mMultiple Airlines
Thu 11/65:40 pmCHS - PTY
3 stops23h 15mMultiple Airlines
Deal found 9/14$675
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/189:55 amPTY - CHS
3 stops22h 11mMultiple Airlines
Tue 11/187:40 pmCHS - PTY
3 stops29h 00mMultiple Airlines
Deal found 9/14$1,051

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sat 10/18

3:15 pm-11:59 pm

1 stop7h 44m

Charleston

Tue 11/18

9:22 am-1:49 pm

1 stop28h 27m

$413

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:30 pm-4:44 pm

1 stop24h 14m

Charleston

Sat 11/1

6:30 am-6:38 pm

1 stop13h 08m

$474

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Thu 10/30

3:15 pm-11:35 am

2 stops19h 20m

Charleston

Thu 11/6

6:40 pm-1:49 pm

2 stops19h 09m

$531

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 10/17

3:15 pm-11:59 pm

1 stop7h 44m

Charleston

Sat 11/1

4:30 pm-1:49 pm

2 stops22h 19m

$605

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest time of day to fly from PTY to CHS?

Find hourly flight availability from Panama City to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 16% on flights from Panama City to Charleston by exploring options for tickets in the evening.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated September 15, 2025.
Read through reviews of airlines operating flights from Panama City to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Crew

8.0

Comfort

7.2

Overall

7.2

Food

6.4

Boarding

7.5

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $413, American Airlines can have you in Charleston from Panama City in 7h 44m. Airlines will cover a distance of 1645 mi.

  • What is the cheapest airline to fly from Panama City to Charleston round-trip?

    Currently priced at $397, American Airlines will fly you from Panama City to Charleston and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Users have found that American Airlines is 25% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Charleston (average of $217). Flying from Panama City to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

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Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Charlotte flights
Panama City to Myrtle Beach flights
Panama City to Greenville flights
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Panama City to Florence flights

Top airline flying from Panama City to Charleston

Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$397Average$546FlexibilityNo cancel feeOn-time71%

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