HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Charleston

$241+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Jan 27 — Feb 31
Tue 1/27
Tue 2/3
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Panama City to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Panama City to Charleston

Best flights from Panama City to Charleston
Discover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 28, 2025.

This American Airlines deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/264:50 pmPTY - CHS
1 stop7h 08mAmerican Airlines
Mon 2/25:09 pmCHS - PTY
2 stops20h 18mAmerican Airlines
Deal found 12/27$494
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/74:41 pmPTY - CHS
1 stop23h 36mUnited Airlines
Tue 1/276:30 amCHS - PTY
1 stop8h 15mUnited Airlines
Deal found 12/28$572
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/74:41 pmPTY - CHS
1 stop23h 36mUnited Airlines
Wed 1/286:30 amCHS - PTY
1 stop10h 37mUnited Airlines
Deal found 12/28$572
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/74:31 pmPTY - CHS
2 stops17h 17mAmerican Airlines
Wed 1/286:00 amCHS - PTY
1 stop7h 27mAmerican Airlines
Deal found 12/28$626
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/72:27 pmPTY - CHS
2 stops19h 21mAmerican Airlines
Tue 1/276:00 amCHS - PTY
1 stop7h 27mAmerican Airlines
Deal found 12/28$639
This United Airlines deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/238:55 amPTY - CHS
1 stop13h 02mUnited Airlines
Sat 1/246:30 amCHS - PTY
1 stop10h 37mUnited Airlines
Deal found 12/26$1,075

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$390
(American Airlines)

One-way from

$241
(United Airlines)

Popular in

March

Cheapest in

August

Average price

$444
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
Search Deals
From Panama City Tocumen Intl to Charleston
Search Deals
One-way flight from Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 28% potential increase in price ($205 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 9% potential price decrease ($44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 28, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 1/26

4:50 pm-11:58 pm

1 stop7h 08m

Charleston

Mon 2/2

5:09 pm-1:27 pm

2 stops20h 18m

$494

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/7

4:41 pm-4:17 pm

1 stop23h 36m

Charleston

Tue 1/27

6:30 am-2:45 pm

1 stop8h 15m

$572

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/7

4:41 pm-4:17 pm

1 stop23h 36m

Charleston

Wed 1/28

6:30 am-5:07 pm

1 stop10h 37m

$572

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/7

4:31 pm-9:48 am

2 stops17h 17m

Charleston

Wed 1/28

6:00 am-1:27 pm

1 stop7h 27m

$626

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 1/7

2:27 pm-9:48 am

2 stops19h 21m

Charleston

Tue 1/27

6:00 am-1:27 pm

1 stop7h 27m

$639

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 1/23

8:55 am-9:57 pm

1 stop13h 02m

Charleston

Sat 1/24

6:30 am-5:07 pm

1 stop10h 37m

$1,075

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Sun 2/15

4:41 pm-4:13 pm

1 stop23h 32m

$241

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 2/11

4:41 pm-4:13 pm

1 stop23h 32m

$312

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 1/5

4:41 pm-4:17 pm

1 stop23h 36m

$484

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/27

Compare providers for flights from Panama City to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $402, American Airlines can have you in Charleston from Panama City in 13h 02m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Charlotte flights
Panama City to Greenville flights
Panama City to Augusta flights
Panama City to Florence flights
Panama City to Myrtle Beach flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.