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$222+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/10. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
feb. 7 — feb. 141
sáb. 2/7
sáb. 2/14
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated enero 8, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$397
(United Airlines)

One-way from

$222
(United Airlines)

Popular in

March

Cheapest in

December

Average price

$615
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
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From Panama City Tocumen Intl to Charleston
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One-way flight from Panama City Tocumen Intl to Charleston
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Highest demand for flights based on searches. 29% potential increase in price ($211 potential increase over avg. RT price).
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Cheapest flight prices on average. 9% potential price decrease ($44 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 8, 2026.

This United Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/47:55 amPTY - CHS
1 stop12h 59mUnited Airlines
vie. 5/87:40 pmCHS - PTY
1 stop9h 24mUnited Airlines
Deal found 1/8$397
This American Airlines deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/122:40 pmPTY - CHS
2 stops20h 49mAmerican Airlines
dom. 3/18:25 pmCHS - PTY
2 stops18h 50mAmerican Airlines
Deal found 1/7$410
This American Airlines deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/41:49 pmPTY - CHS
1 stop19h 35mAmerican Airlines
vie. 5/87:13 pmCHS - PTY
2 stops18h 23mAmerican Airlines
Deal found 1/8$438
This Delta deal was found by Cheapflights users on 1/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 2/123:15 pmPTY - CHS
1 stop8h 39mDelta
dom. 3/15:27 amCHS - PTY
1 stop8h 23mDelta
Deal found 1/7$459
This Expedia deal was found by Cheapflights users on 1/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 5/45:30 amPTY - CHS
2 stops32h 10mMultiple Airlines
vie. 5/88:00 pmCHS - PTY
3 stops19h 55mMultiple Airlines
Deal found 1/8$579
This United Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 1/238:55 amPTY - CHS
1 stop13h 02mUnited Airlines
sáb. 1/246:30 amCHS - PTY
1 stop13h 08mUnited Airlines
Deal found 1/6$1,076
This Kiwi.com deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 1/172:55 amPTY - CHS
2 stops14h 41mMultiple Airlines
dom. 1/188:59 pmCHS - PTY
1 stop11h 23mMultiple Airlines
Deal found 1/6$1,089

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 8, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

lun. 5/4

7:55 am-9:54 pm

1 stop12h 59m

Charleston

vie. 5/8

7:40 pm-4:04 am

1 stop9h 24m

$397

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

lun. 5/4

1:49 pm-11:12 am

2 stops20h 23m

Charleston

vie. 5/8

6:23 pm-12:36 pm

2 stops19h 13m

$438

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

jue. 2/12

3:15 pm-11:54 pm

1 stop8h 39m

Charleston

dom. 3/1

5:27 am-1:50 pm

1 stop8h 23m

$459

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

jue. 2/12

2:40 pm-11:29 am

2 stops20h 49m

Charleston

dom. 3/1

8:25 pm-3:15 pm

2 stops18h 50m

$521

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

lun. 5/4

5:30 am-2:40 pm

2 stops32h 10m

Charleston

vie. 5/8

8:00 pm-2:55 pm

3 stops19h 55m

$579

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

vie. 1/23

8:55 am-9:57 pm

1 stop13h 02m

Charleston

sáb. 1/24

6:30 am-7:38 pm

1 stop13h 08m

$1,076

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

sáb. 1/17

2:55 am-5:36 pm

2 stops14h 41m

Charleston

dom. 1/18

8:59 pm-8:22 am

1 stop11h 23m

$1,089

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

mar. 3/10

3:41 pm-4:08 pm

1 stop23h 27m

$222

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

sáb. 1/17

2:55 am-5:36 pm

2 stops14h 41m

$322

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

dom. 1/18

4:41 pm-4:17 pm

1 stop23h 36m

$334

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Compare providers for flights from Panama City to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $459, United Airlines can have you in Charleston from Panama City in 8h 39m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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