$340+ Cheap flights from Panama City (PTY) to Charleston (CHS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/18. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
Oct 3 — Oct 101
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Charleston with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Charleston
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Best
Last-minute
One-way
Cheapest flights from Panama City to CharlestonExplore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 3, 2026.
This Delta deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 9/1![Delta logo]()
$604
This Expedia deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:55 pm -
2 stops16h 49m
Mon 11/99:40 am -
2 stops16h 30m
Deal found 8/30![Multiple Airlines logo]()
$612
This American Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:13 pm -
2 stops19h 12m
Mon 11/98:14 pm -
1 stop17h 59m
Deal found 9/1![American Airlines logo]()
$639
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 8/30![Delta logo]()
$644
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:02 pm -
1 stop8h 57m
Fri 10/236:00 am -
1 stop8h 02m
Deal found 8/30![American Airlines logo]()
$650
This Travelocity deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:50 pm -
2 stops17h 25m
Mon 10/198:33 pm -
2 stops14h 57m
Deal found 8/31![Multiple Airlines logo]()
$672
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:13 pm -
2 stops20h 11m
Mon 11/98:14 pm -
1 stop17h 59m
Deal found 8/30![American Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
1 stop29h 51m
Thu 10/87:00 am -
1 stop12h 37m
Deal found 9/2![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
2 stops28h 25m
Fri 10/236:50 pm -
2 stops20h 24m
Deal found 8/30![United Airlines logo]()
$680
Best flights from Panama City to CharlestonDiscover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
Discover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 3, 2026.
This Delta deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:24 pm -
1 stop8h 35m
Mon 11/95:20 am -
1 stop8h 42m
Deal found 8/30![Delta logo]()
$644
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:02 pm -
2 stops24h 42m
Fri 10/236:00 am -
1 stop8h 02m
Deal found 8/30![American Airlines logo]()
$654
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
1 stop29h 51m
Thu 10/87:00 am -
1 stop12h 37m
Deal found 9/2![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:30 pm -
1 stop29h 51m
Mon 10/197:00 am -
1 stop13h 31m
Deal found 8/31![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
2 stops28h 25m
Fri 10/236:50 pm -
2 stops20h 24m
Deal found 8/30![United Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops21h 34m
Mon 10/57:00 am -
1 stop13h 31m
Deal found 8/31![United Airlines logo]()
$691
Last-minute flights from Panama City to CharlestonDiscover last-minute flight deals from Panama City to Charleston. Data last updated September 3, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Charleston. Data last updated September 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/31:39 pm -
1 stop9h 20m
Sat 10/107:38 pm -
1 stop18h 24m
Deal found 8/31![American Airlines logo]()
$735
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/173:30 pm -
2 stops31h 41m
Mon 9/217:00 am -
1 stop8h 14m
Deal found 9/2![United Airlines logo]()
$733
This United Airlines deal was found by Cheapflights users on 9/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
1 stop29h 51m
Thu 10/86:30 am -
2 stops14h 01m
Deal found 9/2![United Airlines logo]()
$677
This United Airlines deal was found by Cheapflights users on 9/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
2 stops21h 34m
Mon 10/56:00 am -
2 stops14h 31m
Deal found 9/1![United Airlines logo]()
$691
This American Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/142:02 pm -
1 stop8h 57m
Fri 10/236:00 am -
1 stop8h 02m
Deal found 8/30![American Airlines logo]()
$650
This United Airlines deal was found by Cheapflights users on 8/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:45 am -
2 stops28h 25m
Fri 10/236:50 pm -
2 stops20h 24m
Deal found 8/30![United Airlines logo]()
$680
This Travelocity deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/153:50 pm -
2 stops17h 25m
Mon 10/198:33 pm -
2 stops14h 57m
Deal found 8/31![Multiple Airlines logo]()
$672
One-way flights from Panama City to CharlestonSearch for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
Search for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated September 3, 2026.
This American Airlines deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
1 stop8h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/29![American Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/812:03 pm -
1 stop8h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/31![Multiple Airlines logo]()
$514
This Orbitz deal was found by Cheapflights users on 8/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1811:30 am -
3 stops23h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 8/29![Multiple Airlines logo]()
$632
Find flight deals from Panama City to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $604 (Delta) |
One-way from | $340 (American Airlines) |
Popular in | March |
Cheapest in | December |
Average price | $446 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Fri 12/18
4:33 pm-12:41 am
1 stop8h 08m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$340
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Sun 11/1
3:24 pm-11:59 pm
1 stop8h 35m
Charleston
Mon 11/9
5:20 am-2:02 pm
1 stop8h 42m
$644
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Wed 10/14
2:02 pm-3:44 pm
2 stops24h 42m
Charleston
Fri 10/23
6:00 am-1:02 pm
1 stop8h 02m
$654
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 10/1
3:30 pm-10:21 pm
1 stop29h 51m
Charleston
Thu 10/8
7:00 am-6:37 pm
1 stop12h 37m
$677
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 10/15
3:30 pm-10:21 pm
1 stop29h 51m
Charleston
Mon 10/19
7:00 am-7:31 pm
1 stop13h 31m
$677
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Wed 10/14
9:45 am-3:10 pm
2 stops28h 25m
Charleston
Fri 10/23
6:50 pm-2:14 pm
2 stops20h 24m
$680
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Thu 10/1
3:30 pm-2:04 pm
2 stops21h 34m
Charleston
Mon 10/5
7:00 am-7:31 pm
1 stop13h 31m
$691
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Fri 12/18
2:55 pm-8:55 pm
3 stops30h 00m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$697
Panama CityCharleston
PTY Panama City Tocumen Intl - CHS Charleston
PTYCHS
Panama City Tocumen Intl
Fri 1/8
11:30 am-9:20 am
3 stops21h 50m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$763
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
PTY-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Charleston
What is the cheapest month to book a flight from Panama City to Charleston?
Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $376). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City to Charleston?
Airfare is above average for this route at the moment.
Panama City to Charleston flights typically cost between $431 and $462 in November.The cheapest round-trip price found within the last 5 days was $604 on Delta (Nov 4-Nov 9).
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated September 3, 2026.
Read through reviews of airlines operating flights from Panama City to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Overall
7.1
Food
6.4
Comfort
7.2
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Entertainment
6.8
Overall
7.1
Food
6.4
Comfort
7.2
Boarding
7.5
Crew
7.9
Reviews
1 / 20
2.0
MediocreSherif,Aug 2026
YYZ - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Summerville
Walterboro
Mount Pleasant
Goose Creek
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Complete your trip
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Alternative routes for Panama City to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 3, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Charleston by cabin class
Find flights from Panama City to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Charleston flights
Browse other Panama City and Charleston flight options. Last updated on September 3, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Charleston
Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$431 | Average$642 | FlexibilityNo cancel fee | On-time71% |