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$496+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
May 22 — May 291
Fri 5/22
Fri 5/29
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 22, 2026.

This Delta deal was found by Cheapflights users on 4/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/12:15 pm
PTY
-
CHS
1 stop8h 44m
Delta
Tue 6/165:10 am
CHS
-
PTY
1 stop8h 59m
Delta
Deal found 4/18$496
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/13:30 pm
PTY
-
CHS
2 stops17h 38m
United Airlines
Tue 6/166:50 am
CHS
-
PTY
1 stop12h 47m
United Airlines
Deal found 4/20$517
This United Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:55 am
PTY
-
CHS
1 stop13h 20m
United Airlines
Wed 6/311:18 am
CHS
-
PTY
1 stop9h 13m
United Airlines
Deal found 4/19$526
This American Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/141:24 pm
PTY
-
CHS
2 stops23h 14m
American Airlines
Fri 8/286:00 am
CHS
-
PTY
1 stop7h 24m
American Airlines
Deal found 4/20$536
This United Airlines deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:30 pm
PTY
-
CHS
2 stops17h 34m
United Airlines
Tue 8/256:43 pm
CHS
-
PTY
2 stops20h 31m
United Airlines
Deal found 4/17$549
This United Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:55 am
PTY
-
CHS
2 stops25h 21m
United Airlines
Fri 6/126:00 am
CHS
-
PTY
2 stops23h 04m
United Airlines
Deal found 4/21$555
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/11:14 pm
PTY
-
CHS
2 stops20h 47m
American Airlines
Tue 6/163:12 pm
CHS
-
PTY
2 stops22h 02m
American Airlines
Deal found 4/21$558

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$496
(Delta)

Popular in

March

Cheapest in

December

Average price

$537
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
Search Deals
From Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($71 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 22, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

2:15 pm-11:59 pm

1 stop8h 44m

Charleston

Tue 6/16

5:10 am-1:09 pm

1 stop8h 59m

$496

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Mon 6/1

3:30 pm-10:08 am

2 stops17h 38m

Charleston

Tue 6/16

6:50 am-6:37 pm

1 stop12h 47m

$517
Quickest round-trip

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

2:15 pm-11:59 pm

1 stop8h 44m

Charleston

Wed 6/3

5:15 am-12:50 pm

1 stop8h 35m

$517

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Wed 5/27

7:55 am-10:15 pm

1 stop13h 20m

Charleston

Wed 6/3

11:18 am-7:31 pm

1 stop9h 13m

$526

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

Fri 8/21

3:30 pm-10:04 am

2 stops17h 34m

Charleston

Tue 8/25

6:43 pm-2:14 pm

2 stops20h 31m

$549

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/18

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest month to book a flight from Panama City to Charleston?

Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $376). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Charleston?

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $496, Delta can have you in Charleston from Panama City in 8h 44m. Airlines will cover a distance of 1645 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Charleston?

    Currently, December is the cheapest month in which you can book a flight from Panama City to Charleston (average of $376). Flying from Panama City to Charleston in March is currently the most expensive (average of $715). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Charleston

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