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$451+ Cheap flights from Panama City (PTY) to Charleston (CHS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CHS
nov. 15 — nov. 221
sáb. 11/15
sáb. 11/22
1 adult, Economy
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Find flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on octubre 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/252:53 pmPTY - CHS
1 stop8h 41mAmerican Airlines
lun. 12/298:07 pmCHS - PTY
1 stop19h 47mAmerican Airlines
Deal found 10/16$451
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/173:15 pmPTY - CHS
1 stop7h 44mAmerican Airlines
vie. 10/246:00 amCHS - PTY
1 stop9h 03mAmerican Airlines
Deal found 10/16$579
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/173:30 pmPTY - CHS
1 stop24h 14mUnited Airlines
sáb. 11/15:05 pmCHS - PTY
1 stop27h 33mUnited Airlines
Deal found 10/16$583
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/173:15 pmPTY - CHS
2 stops18h 34mAmerican Airlines
sáb. 11/14:21 pmCHS - PTY
2 stops22h 28mAmerican Airlines
Deal found 10/15$654
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:55 amPTY - CHS
2 stops18h 28mMultiple Airlines
lun. 12/2910:18 pmCHS - PTY
1 stop22h 01mMultiple Airlines
Deal found 10/16$913

Cheap flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated octubre 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$451
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$436
Provider with most accurate pricing for Panama City Tocumen Intl-Charleston flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Charleston flights.
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From Panama City Tocumen Intl to Charleston
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($173 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 16, 2025.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

jue. 12/25

2:53 pm-11:34 pm

1 stop8h 41m

Charleston

lun. 12/29

8:07 pm-3:54 pm

1 stop19h 47m

$451

Panama CityCharleston

PTY - CHS

PTYCHS

Panama City Tocumen Intl

mié. 12/24

2:55 am-9:23 pm

2 stops18h 28m

Charleston

lun. 12/29

10:18 pm-8:19 pm

1 stop22h 01m

$913

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Compare providers for flights from Panama City to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest time of day to fly from PTY to CHS?

Find hourly flight availability from Panama City to Charleston. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated octubre 16, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 15% on flights from Panama City to Charleston by exploring options for tickets in the evening.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated octubre 16, 2025.
Read through reviews of airlines operating flights from Panama City to Charleston, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,043 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.
American Airlines
7.2
Good
11,043 reviews
American Airlines
7.2
Good
11,043 reviews

Comfort

7.2

Crew

8.0

Overall

7.2

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Charleston?

    For as low as $451, American Airlines can have you in Charleston from Panama City in 8h 41m. Airlines will cover a distance of 1645 mi.

  • What is the cheapest airline to fly from Panama City to Charleston round-trip?

    Currently priced at $397, American Airlines will fly you from Panama City to Charleston and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. Users have found that American Airlines is 25% cheaper than the other options available to this destination.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Isle of Palms
Santee
Mount Pleasant
Edisto Beach

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Alternative routes for Panama City to Charleston

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Panama City to Charleston

Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated octubre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$397Average$546FlexibilityNo cancel feeOn-time71%

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