$168+ Cheap flights from Panama City, FL to Charleston (ECP - CHS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Apr 13 — Apr 201
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Charleston with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Charleston
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Best
Last-minute
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Cheapest flights from Panama City to CharlestonExplore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:29 pm
ECP
- CHS
1 stop4h 27m
Delta
Sun 6/77:59 pm
CHS
- ECP
1 stop3h 47m
Delta
Deal found 3/10![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:40 pm
ECP
- CHS
1 stop6h 19m
American Airlines
Mon 5/185:00 am
CHS
- ECP
1 stop6h 03m
American Airlines
Deal found 3/13![American Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/156:40 am
ECP
- CHS
2 stops8h 30m
Southwest
Mon 5/186:00 am
CHS
- ECP
1 stop4h 05m
Southwest
Deal found 3/13![Southwest logo]()
$385
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:55 am
ECP
- CHS
2 stops11h 05m
Southwest
Sun 6/76:35 am
CHS
- ECP
1 stop3h 55m
Southwest
Deal found 3/10![Southwest logo]()
$388
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:16 pm
ECP
- CHS
1 stop6h 43m
American Airlines
Mon 5/255:00 am
CHS
- ECP
1 stop6h 28m
American Airlines
Deal found 3/12![American Airlines logo]()
$395
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:05 am
ECP
- CHS
1 stop5h 30m
Delta
Thu 4/167:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Deal found 3/12![Delta logo]()
$417
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:25 pm
ECP
- CHS
1 stop3h 40m
Southwest
Tue 3/316:15 am
CHS
- ECP
2 stops7h 55m
Southwest
Deal found 3/10![Southwest logo]()
$421
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:05 pm
ECP
- CHS
1 stop6h 55m
Southwest
Thu 4/168:05 am
CHS
- ECP
2 stops12h 45m
Southwest
Deal found 3/12![Southwest logo]()
$444
Best flights from Panama City to CharlestonDiscover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 14, 2026.
Discover carefully curated flight deals from Panama City to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 14, 2026.
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/159:55 am
ECP
- CHS
2 stops10h 35m
Southwest
Mon 5/186:00 am
CHS
- ECP
1 stop4h 05m
Southwest
Deal found 3/11![Southwest logo]()
$389
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:05 am
ECP
- CHS
1 stop5h 30m
Delta
Thu 4/167:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Deal found 3/12![Delta logo]()
$417
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/910:48 am
ECP
- CHS
1 stop6h 01m
American Airlines
Sun 4/125:00 am
CHS
- ECP
1 stop6h 03m
American Airlines
Deal found 3/9![American Airlines logo]()
$606
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:30 am
ECP
- CHS
1 stop14h 29m
United Airlines
Wed 5/136:35 am
CHS
- ECP
1 stop16h 30m
United Airlines
Deal found 3/11![United Airlines logo]()
$677
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1510:10 am
ECP
- CHS
2 stops8h 50m
Southwest
Thu 4/168:05 am
CHS
- ECP
2 stops12h 45m
Southwest
Deal found 3/12![Southwest logo]()
$449
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/310:10 am
ECP
- CHS
2 stops8h 50m
Southwest
Sun 6/711:00 am
CHS
- ECP
2 stops8h 30m
Southwest
Deal found 3/10![Southwest logo]()
$521
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/282:50 pm
ECP
- CHS
1 stop5h 50m
Southwest
Wed 4/16:15 am
CHS
- ECP
2 stops7h 55m
Southwest
Deal found 3/12![Southwest logo]()
$522
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/229:55 am
ECP
- CHS
2 stops8h 25m
Southwest
Mon 5/256:00 am
CHS
- ECP
1 stop4h 05m
Southwest
Deal found 3/12![Southwest logo]()
$588
Last-minute flights from Panama City to CharlestonDiscover last-minute flight deals from Panama City to Charleston. Data last updated March 14, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Charleston. Data last updated March 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/259:25 am
ECP
- CHS
1 stop2h 56m
Delta
Tue 3/316:30 am
CHS
- ECP
1 stop3h 10m
Delta
Deal found 3/10![Delta logo]()
$455
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/251:20 pm
ECP
- CHS
1 stop6h 10m
Southwest
Sun 3/296:15 am
CHS
- ECP
1 stop10h 20m
Southwest
Deal found 3/10![Southwest logo]()
$519
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/271:25 pm
ECP
- CHS
1 stop3h 40m
Southwest
Tue 3/316:15 am
CHS
- ECP
2 stops7h 55m
Southwest
Deal found 3/10![Southwest logo]()
$421
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/284:39 pm
ECP
- CHS
1 stop5h 22m
American Airlines
Wed 4/15:10 am
CHS
- ECP
1 stop5h 56m
American Airlines
Deal found 3/12![American Airlines logo]()
$517
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/282:50 pm
ECP
- CHS
1 stop5h 50m
Southwest
Wed 4/16:15 am
CHS
- ECP
2 stops7h 55m
Southwest
Deal found 3/12![Southwest logo]()
$522
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:05 am
ECP
- CHS
1 stop5h 30m
Delta
Thu 4/167:44 pm
CHS
- ECP
1 stop4h 28m
Delta
Deal found 3/12![Delta logo]()
$417
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:05 pm
ECP
- CHS
1 stop6h 55m
Southwest
Thu 4/168:05 am
CHS
- ECP
2 stops12h 45m
Southwest
Deal found 3/12![Southwest logo]()
$444
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:40 pm
ECP
- CHS
1 stop6h 19m
American Airlines
Sun 4/196:35 am
CHS
- ECP
1 stop4h 28m
American Airlines
Deal found 3/10![American Airlines logo]()
$470
One-way flights from Panama City to CharlestonSearch for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated March 14, 2026.
Search for one-way flight options from Panama City to Charleston. Find affordable one-way fares based on user searches. Data last updated March 14, 2026.
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:00 am
ECP
- CHS
1 stop4h 24m
Delta
Deal found 3/11![Delta logo]()
$168
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1410:48 am
ECP
- CHS
1 stop4h 18m
American Airlines
Deal found 3/14![American Airlines logo]()
$183
This Southwest deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:20 am
ECP
- CHS
1 stop3h 40m
Southwest
Deal found 3/10![Southwest logo]()
$187
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/104:17 pm
ECP
- CHS
1 stop4h 47m
American Airlines
Deal found 3/10![American Airlines logo]()
$198
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/87:15 am
ECP
- CHS
2 stops10h 20m
Southwest
Deal found 3/11![Southwest logo]()
$221
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:35 am
ECP
- CHS
2 stops8h 25m
Southwest
Deal found 3/13![Southwest logo]()
$264
This Southwest deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:10 am
ECP
- CHS
1 stop4h 25m
Southwest
Deal found 3/11![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:20 am
ECP
- CHS
1 stop3h 45m
Southwest
Deal found 3/13![Southwest logo]()
$321
This Delta deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:43 pm
ECP
- CHS
1 stop4h 33m
Delta
Deal found 3/13![Delta logo]()
$331
Find flight deals from Panama City to Charleston
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $375 (Delta) |
One-way from | $168 (Delta) |
Popular in | April |
Cheapest in | August |
Average price | $419 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Fri 5/15
9:55 am-9:30 pm
2 stops10h 35m
Charleston
Mon 5/18
6:00 am-9:05 am
1 stop4h 05m
$389
Quickest round-trip
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Wed 4/15
7:05 am-1:35 pm
1 stop5h 30m
Charleston
Thu 4/16
7:44 pm-11:12 pm
1 stop4h 28m
$417
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Wed 4/15
10:10 am-8:00 pm
2 stops8h 50m
Charleston
Thu 4/16
8:05 am-7:50 pm
2 stops12h 45m
$449
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Wed 6/3
10:10 am-8:00 pm
2 stops8h 50m
Charleston
Sun 6/7
11:00 am-6:30 pm
2 stops8h 30m
$521
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Sat 3/28
2:50 pm-9:40 pm
1 stop5h 50m
Charleston
Wed 4/1
6:15 am-1:10 pm
2 stops7h 55m
$522
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Fri 5/22
9:55 am-7:20 pm
2 stops8h 25m
Charleston
Mon 5/25
6:00 am-9:05 am
1 stop4h 05m
$588
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Thu 4/9
10:48 am-5:49 pm
1 stop6h 01m
Charleston
Sun 4/12
5:00 am-10:03 am
1 stop6h 03m
$606
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Tue 5/12
6:30 am-9:59 pm
1 stop14h 29m
Charleston
Wed 5/13
6:35 am-10:05 pm
1 stop16h 30m
$677
Cheapest one-way
Quickest one-way
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Sat 5/9
7:20 am-12:00 pm
1 stop3h 40m
$187
Panama CityCharleston
ECP - CHS
ECPCHS
Panama City NW Florida Beaches
Fri 7/10
4:17 pm-10:04 pm
1 stop4h 47m
$198
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Panama City to Charleston
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City, Florida-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Charleston flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City, Florida-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Charleston
Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
ECP-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Charleston
What is the cheapest month to book a flight from Panama City, Florida to Charleston?
Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Charleston (average of $96). Flying from Panama City, Florida to Charleston in February is currently the most expensive (average of $350). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Panama City, Florida to Charleston?
Reviews of airlines servicing Charleston
Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated March 14, 2026.
See what other customers who have flown with Delta and American Airlines from Panama City to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Crew
8.5
Boarding
8.1
Food
7.2
Overall
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Charleston?
Book flights to Charleston if you plan to visit one of these locationsNorth Charleston
Santee
Walterboro
Summerville
Isle of Palms
Mount Pleasant
Edisto Beach
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Complete your trip
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Alternative routes for Panama City to Charleston
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Charleston
Explore flights to Charleston departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 14, 2026.
Complete your trip
Complete your trip to Charleston by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Charleston by cabin class
Find flights from Panama City to Charleston, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Charleston flights
Browse other Panama City and Charleston flight options. Last updated on March 14, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on March 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Panama City to Charleston
Discover the top 2 airlines that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$335 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$276 | Average$346 | FlexibilityNo cancel fee | On-time71% |