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$183+ Cheap flights from Panama City, FL to Charleston (ECP - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/3. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — CHS
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Panama City to Charleston

Cheapest flights from Panama City to Charleston
Explore the most affordable flight options available from Panama City to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:10 pm
ECP
-
CHS
1 stop3h 45m
Delta
Tue 5/52:21 pm
CHS
-
ECP
1 stop6h 15m
Delta
Deal found 1/27$335
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:19 am
ECP
-
CHS
1 stop5h 34m
American Airlines
Sat 3/218:17 pm
CHS
-
ECP
1 stop4h 32m
American Airlines
Deal found 1/27$354
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:49 am
ECP
-
CHS
1 stop4h 31m
Delta
Sat 5/95:30 am
CHS
-
ECP
1 stop3h 47m
Delta
Deal found 1/27$355
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:40 pm
ECP
-
CHS
1 stop6h 19m
American Airlines
Fri 5/88:21 pm
CHS
-
ECP
1 stop4h 25m
American Airlines
Deal found 1/27$374
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:31 pm
ECP
-
CHS
1 stop4h 24m
Delta
Sun 5/107:59 pm
CHS
-
ECP
1 stop3h 47m
Delta
Deal found 1/27$375
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/37:00 am
ECP
-
CHS
2 stops11h 03m
American Airlines
Tue 6/98:33 pm
CHS
-
ECP
1 stop4h 08m
American Airlines
Deal found 1/27$380
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:49 am
ECP
-
CHS
2 stops11h 20m
Delta
Thu 5/75:30 am
CHS
-
ECP
1 stop3h 47m
Delta
Deal found 1/27$385
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:55 am
ECP
-
CHS
2 stops8h 10m
Southwest
Tue 6/96:35 am
CHS
-
ECP
2 stops11h 10m
Southwest
Deal found 1/27$391
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:34 pm
ECP
-
CHS
1 stop5h 27m
American Airlines
Sun 2/225:10 am
CHS
-
ECP
1 stop5h 56m
American Airlines
Deal found 1/28$394
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:30 pm
ECP
-
CHS
1 stop4h 26m
Delta
Sun 6/77:59 pm
CHS
-
ECP
1 stop3h 47m
Delta
Deal found 1/27$395
This Southwest deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/164:55 pm
ECP
-
CHS
1 stop3h 45m
Southwest
Sat 3/217:55 am
CHS
-
ECP
2 stops10h 40m
Southwest
Deal found 1/27$403

Find flight deals from Panama City to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (ECP) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$335
(Delta)

One-way from

$183
(Southwest)

Popular in

April

Cheapest in

August

Average price

$515
Provider with most accurate pricing for Panama City NW Florida Beaches-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Charleston flights.
Search Deals
From Panama City NW Florida Beaches to Charleston
Search Deals
One-way flight from Panama City NW Florida Beaches to Charleston
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Panama City to Charleston that are best for you.

Fly from

Panama City

Fly to

Charleston

Route

Depart

Return

Price

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 6/2

5:30 pm-11:56 pm

1 stop5h 26m

Charleston

Wed 6/10

10:30 am-12:38 pm

1 stop3h 08m

$335

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Mon 3/16

7:19 am-1:53 pm

1 stop5h 34m

Charleston

Sat 3/21

8:17 pm-11:49 pm

1 stop4h 32m

$354

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sat 6/6

6:00 am-11:24 am

1 stop4h 24m

Charleston

Wed 6/10

7:30 am-10:14 am

1 stop3h 44m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Sun 6/7

7:05 pm-11:57 pm

1 stop3h 52m

Charleston

Tue 6/9

6:30 am-10:14 am

1 stop4h 44m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 6/4

4:10 pm-9:44 pm

1 stop4h 34m

Charleston

Tue 6/9

10:30 am-12:38 pm

1 stop3h 08m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 4/30

4:31 pm-9:55 pm

1 stop4h 24m

Charleston

Wed 5/6

4:35 pm-7:36 pm

1 stop4h 01m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Wed 4/29

5:49 am-11:20 am

1 stop4h 31m

Charleston

Thu 5/7

5:30 am-8:17 am

1 stop3h 47m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 4/28

5:49 am-11:20 am

1 stop4h 31m

Charleston

Sat 5/9

5:30 am-8:17 am

1 stop3h 47m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Thu 4/23

5:49 am-10:09 am

1 stop3h 20m

Charleston

Sun 4/26

5:20 am-8:35 am

1 stop4h 15m

$355

Panama CityCharleston

ECP - CHS

ECPCHS

Panama City NW Florida Beaches

Tue 4/28

5:10 pm-11:50 pm

1 stop5h 40m

Charleston

Thu 5/7

5:30 am-8:17 am

1 stop3h 47m

$355

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 21 results
1
2
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Compare providers for flights from Panama City to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Charleston in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City, Florida-Charleston flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City, Florida-Charleston flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City, Florida-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City, Florida-Charleston flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Charleston

What is the cheapest month to book a flight from Panama City, Florida to Charleston?

Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Charleston (average of $96). Flying from Panama City, Florida to Charleston in January is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated January 29, 2026.
See what other customers who have flown with Delta from Panama City to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Boarding

8.1

Entertainment

7.8

Food

7.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City, Florida to Charleston?

    For as low as $335, Delta can have you in Charleston from Panama City, Florida in 5h 26m. The distance between Panama City, Florida and Charleston is about 381 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Panama City, Florida to Charleston round-trip?

    Our cheapest airline available from Panama City, Florida to Charleston is Delta. Our recent data shows that you can find tickets from as low as $196 on this airline. Delta is 50% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Panama City to Charleston that include hotel bookings?

    Yes. In addition to deals on Panama City to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Charleston.

  • Can I find deals for business class flights from Panama City to Charleston?

    Yes. Cheapflights offers flight deals from Panama City to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Charleston?

    Currently, October is the cheapest month in which you can book a flight from Panama City, Florida to Charleston (average of $96). Flying from Panama City, Florida to Charleston in January is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Charleston

Discover the top airline that operate flights from Panama City to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$196Average$386FlexibilityNo cancel feeOn-timeN/A

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