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$86+ Cheap flights from Key West to Charleston (EYW - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Jan 25 — Feb 11
Sun 1/25
Sun 2/1
1 adult, Economy
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Cheap flight deals from Key West to Charleston

Best flights from Key West to Charleston
Discover carefully curated flight deals from Key West to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/74:06 pmEYW - CHS
1 stop22h 25mMultiple Airlines
Fri 1/98:28 pmCHS - EYW
1 stop13h 41mMultiple Airlines
Deal found 12/25$236
This Delta deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/812:24 pmEYW - CHS
1 stop5h 29mDelta
Mon 1/128:00 amCHS - EYW
1 stop5h 48mDelta
Deal found 12/23$447
This American Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/84:37 pmEYW - CHS
2 stops6h 30mAmerican Airlines
Mon 1/129:33 amCHS - EYW
1 stop3h 30mAmerican Airlines
Deal found 12/23$452
This Kiwi.com deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/74:06 pmEYW - CHS
2 stops25h 30mMultiple Airlines
Sat 1/106:35 pmCHS - EYW
1 stop17h 21mMultiple Airlines
Deal found 12/25$240
This United Airlines deal was found by Cheapflights users on 12/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:05 pmEYW - CHS
1 stop24h 59mUnited Airlines
Sun 1/257:45 pmCHS - EYW
1 stop20h 37mUnited Airlines
Deal found 12/23$547
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/712:00 pmEYW - CHS
2 stops7h 02mAmerican Airlines
Sat 1/102:06 pmCHS - EYW
2 stops9h 50mAmerican Airlines
Deal found 12/25$552

Find flight deals from Key West to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$231
(Kiwi.com)

One-way from

$86
(Kiwi.com)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Key West to Charleston
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One-way flight from Key West to Charleston
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
Use the filters below to find and compare flights from Key West to Charleston that are best for you.

Fly from

Key West

Fly to

Charleston

Route

Depart

Return

Price

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 1/7

4:06 pm-2:31 pm

1 stop22h 25m

Charleston

Fri 1/9

8:28 pm-10:09 am

1 stop13h 41m

$236

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 1/7

4:06 pm-5:36 pm

2 stops25h 30m

Charleston

Sat 1/10

6:35 pm-11:56 am

1 stop17h 21m

$240

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/8

12:24 pm-5:53 pm

1 stop5h 29m

Charleston

Mon 1/12

8:00 am-1:48 pm

1 stop5h 48m

$447

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/8

4:37 pm-11:07 pm

2 stops6h 30m

Charleston

Mon 1/12

9:33 am-1:03 pm

1 stop3h 30m

$452

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/22

6:05 pm-7:04 pm

1 stop24h 59m

Charleston

Sun 1/25

7:45 pm-4:22 pm

1 stop20h 37m

$547

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 1/7

12:00 pm-7:02 pm

2 stops7h 02m

Charleston

Sat 1/10

2:06 pm-11:56 pm

2 stops9h 50m

$552

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/29

10:06 am-8:43 am

1 stop22h 37m

$95

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Sun 5/17

12:05 pm-8:43 am

1 stop20h 38m

$101

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 6/23

1:14 pm-3:28 pm

1 stop26h 14m

$116

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Sun 6/7

12:05 pm-8:43 am

1 stop20h 38m

$122

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Showing 1-10 of 15 results
1
2

Compare providers for flights from Key West to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Charleston in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated December 26, 2025.
See what other customers who have flown with American Airlines from Key West to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,067 reviews

Food

6.5

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,067 reviews
American Airlines
7.2
Good
11,067 reviews

Food

6.5

Crew

8.0

Comfort

7.2

Overall

7.2

Boarding

7.5

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key West to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Charleston?

    Airlines like Delta fly from Key West to Charleston in about 5h 29m. The time it takes to get you to your destination can typically vary by up to . There are 585 mi between Key West and Charleston.

  • What is the cheapest airline to fly from Key West to Charleston round-trip?

    According to our current data, American Airlines ($387), offers the cheapest pricing from Key West to Charleston.

  • Can I find deals for flights from Key West to Charleston that include hotel bookings?

    Yes. In addition to deals on Key West to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Charleston.

  • Can I find deals for business class flights from Key West to Charleston?

    Yes. Cheapflights offers flight deals from Key West to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Top airline flying from Key West to Charleston

Discover the top airline that operate flights from Key West to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$387Average$658FlexibilityNo cancel feeOn-time71%

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