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$74+ Cheap flights from Key West to Charleston (EYW - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Key West to Charleston

Cheapest flights from Key West to Charleston
Explore the most affordable flight options available from Key West to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This Breeze Airways deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2310:59 amEYW - CHS
1 stop3h 44mBreeze Airways
Tue 12/309:08 pmCHS - EYW
1 stop9h 59mBreeze Airways
Deal found 12/16$443
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:25 amEYW - CHS
1 stop4h 11mDelta
Tue 12/302:41 pmCHS - EYW
1 stop6h 17mDelta
Deal found 12/15$507
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:55 pmEYW - CHS
1 stop4h 52mAmerican Airlines
Tue 12/305:10 amCHS - EYW
2 stops8h 03mAmerican Airlines
Deal found 12/16$547

Find flight deals from Key West to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$285
(Breeze Airways)

One-way from

$74
(Breeze Airways)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Key West to Charleston
Search Deals
One-way flight from Key West to Charleston
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Key West to Charleston that are best for you.

Fly from

Key West

Fly to

Charleston

Route

Depart

Return

Price

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/1

10:59 am-2:28 pm

1 stop3h 29m

Charleston

Thu 1/1

8:53 pm-9:17 am

1 stop12h 24m

$285

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 1/16

9:49 am-1:22 pm

1 stop3h 33m

Charleston

Sun 1/18

3:01 pm-12:26 pm

1 stop21h 25m

$314

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 1/16

12:00 pm-6:40 pm

1 stop6h 40m

Charleston

Sun 1/18

6:10 am-1:03 pm

2 stops6h 53m

$358

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/1

10:59 am-2:28 pm

1 stop3h 29m

Charleston

Thu 1/1

10:18 pm-9:45 pm

2 stops23h 27m

$359

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 1/23

6:05 pm-2:48 pm

1 stop20h 43m

Charleston

Sun 1/25

7:45 pm-4:22 pm

1 stop20h 37m

$538

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/29

10:06 am-8:43 am

1 stop22h 37m

$74

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 1/29

1:33 pm-9:11 pm

2 stops7h 38m

$294

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Compare providers for flights from Key West to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Charleston in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated December 16, 2025.
See what other customers who have flown with American Airlines from Key West to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,048 reviews

Food

6.5

Comfort

7.2

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,048 reviews
American Airlines
7.2
Good
11,048 reviews

Food

6.5

Comfort

7.2

Boarding

7.5

Overall

7.2

Entertainment

6.9

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key West to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Charleston?

    Airlines like Breeze Airways and American Airlines fly from Key West to Charleston in about 3h 29m. The time it takes to get you to your destination can typically vary by up to 3h 11m. There are 585 mi between Key West and Charleston. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Key West to Charleston round-trip?

    According to our current data, American Airlines ($387), offers the cheapest pricing from Key West to Charleston.

  • Can I find deals for flights from Key West to Charleston that include hotel bookings?

    Yes. In addition to deals on Key West to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Charleston.

  • Can I find deals for business class flights from Key West to Charleston?

    Yes. Cheapflights offers flight deals from Key West to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Top airline flying from Key West to Charleston

Discover the top airline that operate flights from Key West to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$387Average$658FlexibilityNo cancel feeOn-time71%

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