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$120+ Cheap flights from Key West to Charleston (EYW - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
août 26 — sept. 21
mar. 8/26
mar. 9/2
1 adult, Economy
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Cheap flight deals from Key West to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated août 21, 2025.

Round-trip from

$347
(Delta)

One-way from

$120
(Expedia)

Popular in

February

Cheapest in

September

Average price

$688
From Key West to Charleston
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One-way flight from Key West to Charleston
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Highest demand for flights based on searches. 24% potential increase in price ($185 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Key West to Charleston

Cheapest flights from Key West to Charleston
Explore the most affordable flight options available from Key West to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on août 21, 2025.

This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/52:00 pmEYW - CHS
1 stop4h 57mDelta
mar. 9/96:20 amCHS - EYW
1 stop6h 45mDelta
Deal found 8/21$347
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 9/511:25 amEYW - CHS
2 stops9h 30mAmerican Airlines
mar. 9/97:08 amCHS - EYW
1 stop6h 21mAmerican Airlines
Deal found 8/21$352
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/254:53 pmEYW - CHS
1 stop7h 03mAmerican Airlines
sam. 11/295:10 amCHS - EYW
1 stop6h 49mAmerican Airlines
Deal found 8/20$454
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/2912:50 pmEYW - CHS
1 stop4h 26mAmerican Airlines
lun. 9/16:00 amCHS - EYW
1 stop5h 46mAmerican Airlines
Deal found 8/21$507
This Gotogate deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ven. 8/2910:02 amEYW - CHS
2 stops28h 06mBreeze Airways
lun. 9/13:10 pmCHS - EYW
3 stops41h 57mBreeze Airways
Deal found 8/21$912
This KAYAK deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2510:59 amEYW - CHS
2 stops11h 15mBreeze Airways
sam. 11/298:10 pmCHS - EYW
3 stops38h 21mBreeze Airways
Deal found 8/20$1,146

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated août 21, 2025.
Use the filters below to find and compare flights from Key West to Charleston that are best for you.

Fly from

Key West

Fly to

Charleston

Route

Depart

Return

Price

Key WestCharleston

EYW - CHS

EYWCHS

Key West

mer. 9/10

7:00 am-11:50 am

1 stop4h 50m

Charleston

mar. 9/23

5:10 am-10:55 am

1 stop5h 45m

$347

Key WestCharleston

EYW - CHS

EYWCHS

Key West

ven. 9/5

2:00 pm-6:57 pm

1 stop4h 57m

Charleston

mar. 9/9

6:20 am-1:05 pm

1 stop6h 45m

$347

Key WestCharleston

EYW - CHS

EYWCHS

Key West

ven. 9/5

11:25 am-8:55 pm

2 stops9h 30m

Charleston

mar. 9/9

7:08 am-1:29 pm

1 stop6h 21m

$352

Key WestCharleston

EYW - CHS

EYWCHS

Key West

mer. 9/10

11:25 am-10:57 pm

2 stops11h 32m

Charleston

mar. 9/23

6:27 am-11:13 am

1 stop4h 46m

$352

Key WestCharleston

EYW - CHS

EYWCHS

Key West

mar. 11/25

4:53 pm-11:56 pm

1 stop7h 03m

Charleston

sam. 11/29

5:10 am-11:59 am

1 stop6h 49m

$454

Key WestCharleston

EYW - CHS

EYWCHS

Key West

mar. 11/25

10:59 am-10:14 pm

2 stops11h 15m

Charleston

sam. 11/29

8:10 pm-10:31 am

3 stops38h 21m

$1,146

Key WestCharleston

EYW - CHS

EYWCHS

Key West

dim. 9/28

8:55 am-8:57 am

1 stop24h 02m

$120

Key WestCharleston

EYW - CHS

EYWCHS

Key West

ven. 8/29

1:47 pm-9:14 am

1 stop19h 27m

$168

Key WestCharleston

EYW - CHS

EYWCHS

Key West

dim. 9/28

12:29 pm-9:05 am

2 stops20h 36m

$199

Key WestCharleston

EYW - CHS

EYWCHS

Key West

ven. 8/29

10:33 am-6:46 pm

2 stops32h 13m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/21

Best time to book a flight from Key West to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated août 21, 2025.
See what other customers who have flown with American Airlines from Key West to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Overall

7.2

Food

6.5

Entertainment

6.9

Comfort

7.2

Boarding

7.5

Crew

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key West to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Charleston?

    Airlines like Delta and American Airlines fly from Key West to Charleston in about 4h 50m. The time it takes to get you to your destination can typically vary by up to 4h 40m. There are 585 mi between Key West and Charleston. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Key West to Charleston round-trip?

    According to our current data, American Airlines ($492), offers the cheapest pricing from Key West to Charleston. American Airlines is currently priced 15% below the average price you’ll pay for this route.

  • Can I find deals for flights from Key West to Charleston that include hotel bookings?

    Yes. In addition to deals on Key West to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Charleston.

  • Can I find deals for business class flights from Key West to Charleston?

    Yes. Cheapflights offers flight deals from Key West to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Key West to Charleston (average of $217). Flying from Key West to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

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Top airline flying from Key West to Charleston

Discover the top airline that operate flights from Key West to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated août 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$492Average$658FlexibilityNo cancel feeOn-time71%

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