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$79+ Cheap flights from Key West to Charleston (EYW - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/12. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Dec 4 — Dec 111
Thu 12/4
Thu 12/11
1 adult, Economy
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Cheap flight deals from Key West to Charleston

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to Charleston (CHS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$301
(Breeze Airways)

One-way from

$79
(Kiwi.com)

Popular in

February

Cheapest in

September

Average price

$553
Provider with most accurate pricing for Key West-Charleston flight deals.
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Provider most trusted by Cheapflights users for Key West-Charleston flights.
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From Key West to Charleston
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One-way flight from Key West to Charleston
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Highest demand for flights based on searches. 25% potential increase in price ($199 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($66 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Key West to Charleston

Cheapest flights from Key West to Charleston
Explore the most affordable flight options available from Key West to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2025.

This Breeze Airways deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1510:47 amEYW - CHS
1 stop3h 42mBreeze Airways
Sun 11/162:59 pmCHS - EYW
1 stop17h 16mBreeze Airways
Deal found 11/3$301
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2512:28 pmEYW - CHS
2 stops42h 58mMultiple Airlines
Sun 11/302:59 pmCHS - EYW
1 stop17h 16mMultiple Airlines
Deal found 11/3$400
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/254:53 pmEYW - CHS
1 stop5h 11mAmerican Airlines
Sun 11/306:49 amCHS - EYW
1 stop7h 25mAmerican Airlines
Deal found 11/3$442
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/154:18 pmEYW - CHS
2 stops7h 38mAmerican Airlines
Sun 11/165:10 amCHS - EYW
2 stops6h 04mAmerican Airlines
Deal found 11/3$577
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/183:00 pmEYW - CHS
2 stops24h 09mUnited Airlines
Sat 11/227:45 pmCHS - EYW
3 stops18h 01mUnited Airlines
Deal found 11/3$686

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
Use the filters below to find and compare flights from Key West to Charleston that are best for you.

Fly from

Key West

Fly to

Charleston

Route

Depart

Return

Price

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Sat 11/15

10:47 am-2:29 pm

1 stop3h 42m

Charleston

Sun 11/16

2:59 pm-8:15 am

1 stop17h 16m

$301

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 11/25

12:28 pm-7:26 am

2 stops42h 58m

Charleston

Sun 11/30

2:59 pm-8:15 am

1 stop17h 16m

$400

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 11/25

4:53 pm-10:04 pm

1 stop5h 11m

Charleston

Sun 11/30

6:49 am-2:14 pm

1 stop7h 25m

$442

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 3/10

1:01 pm-11:35 am

1 stop22h 34m

Charleston

Wed 3/11

5:16 pm-10:21 am

1 stop17h 05m

$522

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Sat 11/15

4:18 pm-11:56 pm

2 stops7h 38m

Charleston

Sun 11/16

5:10 am-11:14 am

2 stops6h 04m

$577

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 3/10

8:01 pm-11:20 pm

1 stop3h 19m

Charleston

Wed 3/11

12:49 pm-6:30 pm

2 stops5h 41m

$582

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 11/18

3:00 pm-3:09 pm

2 stops24h 09m

Charleston

Sat 11/22

7:45 pm-1:46 pm

3 stops18h 01m

$686

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Wed 11/12

10:47 am-2:29 pm

1 stop3h 42m

$79

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 11/13

8:55 am-8:57 am

1 stop24h 02m

$108

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Tue 11/11

11:45 am-2:29 pm

1 stop26h 44m

$148

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 16 results
1
2

Compare providers for flights from Key West to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Key West to Charleston in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Key West-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Key West-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Key West-Charleston flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Key West-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Key West-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Key West to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to Charleston

How much does it cost to fly round-trip from Key West to Charleston?

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated November 4, 2025.
See what other customers who have flown with American Airlines from Key West to Charleston have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,038 reviews

Entertainment

6.9

Food

6.4

Crew

8.0

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,038 reviews
American Airlines
7.2
Good
11,038 reviews

Entertainment

6.9

Food

6.4

Crew

8.0

Overall

7.2

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Key West to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Key West to Charleston?

    Airlines like Breeze Airways and American Airlines fly from Key West to Charleston in about 3h 42m. The time it takes to get you to your destination can typically vary by up to 1h 29m. There are 585 mi between Key West and Charleston. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Key West to Charleston round-trip?

    According to our current data, American Airlines ($387), offers the cheapest pricing from Key West to Charleston. American Airlines is currently priced 32% below the average price you’ll pay for this route.

  • Can I find deals for flights from Key West to Charleston that include hotel bookings?

    Yes. In addition to deals on Key West to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to Charleston.

  • Can I find deals for business class flights from Key West to Charleston?

    Yes. Cheapflights offers flight deals from Key West to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Isle of Palms
Santee
Mount Pleasant
Edisto Beach

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Top airline flying from Key West to Charleston

Discover the top airline that operate flights from Key West to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$387Average$658FlexibilityNo cancel feeOn-time71%

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