How long is the flight from Indianapolis to Buffalo?

Airlines like American Airlines and Southwest fly from Indianapolis to Buffalo in about 4h 44m. The time it takes to get you to your destination can typically vary by up to 3h 36m. The distance between Indianapolis and Buffalo is about 451 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Indianapolis to Buffalo round-trip?

According to our current data, Frontier ($60), Delta ($83), and American Airlines ($205) offers the cheapest pricing from Indianapolis to Buffalo. Frontier is 84% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Indianapolis to Buffalo one-way?

One-way options have recently been found by users for as low as $87 on American Airlines. Other airlines that offer cheap prices include Southwest from $117 and Delta from $124 one-way.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What are the most popular airlines that fly from Indianapolis to Buffalo?

When booking a flight from Indianapolis to Buffalo, you may want to consider flying on American Airlines, Delta or Southwest as they are the most popular for this route.

What is the cheapest time of day to fly from IND to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Indianapolis to Buffalo as you normally would.

Most accurate provider : When it comes to deals on Indianapolis-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Buffalo flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Indianapolis-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Indianapolis to Buffalo that include hotel bookings?

Yes. In addition to deals on Indianapolis to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Indianapolis to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Buffalo.

Can I find deals for business class flights from Indianapolis to Buffalo?

Yes. Cheapflights offers flight deals from Indianapolis to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$153+ Flights from Indianapolis to Buffalo

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Indianapolis to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Indianapolis to Buffalo

Cheapest flights from Indianapolis to Buffalo
Explore the most affordable flight options available from Indianapolis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Mon 12/295:32 pmIND - BUF

1 stop6h 27mAmerican Airlines

Sat 1/36:00 amBUF - IND

1 stop4h 32mAmerican Airlines

Deal found 12/28

$677

Tue 12/308:00 amIND - BUF

1 stop7h 09mDelta

Wed 12/316:10 amBUF - IND

1 stop5h 19mDelta

Deal found 12/27

$741

Tue 12/305:20 amIND - BUF

1 stop6h 30mSouthwest

Wed 12/318:05 amBUF - IND

2 stops9h 40mSouthwest

Deal found 12/27

$746

Mon 12/297:45 pmIND - BUF

2 stops14h 01mUnited Airlines

Sat 1/36:00 amBUF - IND

2 stops11h 03mUnited Airlines

Deal found 12/28

$947

Best flights from Indianapolis to Buffalo
Discover carefully curated flight deals from Indianapolis to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 30, 2025.

Fri 2/610:38 amIND - BUF

1 stop7h 58mMultiple Airlines

Sun 2/811:02 amBUF - IND

1 stop22h 41mMultiple Airlines

Deal found 12/30

$185

Wed 1/217:01 amIND - BUF

1 stop3h 50mAmerican Airlines

Wed 1/215:27 pmBUF - IND

1 stop5h 01mAmerican Airlines

Deal found 12/29

$257

Tue 1/278:45 amIND - BUF

2 stops8h 20mSouthwest

Tue 2/33:45 pmBUF - IND

1 stop4h 25mSouthwest

Deal found 12/28

$262

Sat 1/172:00 pmIND - BUF

1 stop6h 29mUnited Airlines

Sun 1/188:30 amBUF - IND

1 stop4h 48mUnited Airlines

Deal found 12/27

$319

Fri 1/302:12 pmIND - BUF

1 stop21h 22mMultiple Airlines

Thu 2/57:59 pmBUF - IND

1 stop13h 44mMultiple Airlines

Deal found 12/30

$198

Wed 1/215:35 amIND - BUF

1 stop6h 55mSouthwest

Wed 1/213:45 pmBUF - IND

2 stops6h 20mSouthwest

Deal found 12/30

$314

Thu 1/156:55 amIND - BUF

2 stops11h 24mMultiple Airlines

Sun 1/187:14 pmBUF - IND

1 stop20h 20mMultiple Airlines

Deal found 12/28

$310

Wed 1/146:00 amIND - BUF

2 stops27h 21mMultiple Airlines

Sun 1/188:58 pmBUF - IND

1 stop26h 17mMultiple Airlines

Deal found 12/29

$318

Last-minute flights from Indianapolis to Buffalo
Discover last-minute flight deals from Indianapolis to Buffalo. Data last updated December 30, 2025 and is based on user searches.

Wed 1/146:00 amIND - BUF

2 stops27h 21mMultiple Airlines

Sun 1/188:58 pmBUF - IND

1 stop26h 17mMultiple Airlines

Deal found 12/29

$318

Thu 1/156:55 amIND - BUF

2 stops11h 24mMultiple Airlines

Sun 1/187:14 pmBUF - IND

1 stop20h 20mMultiple Airlines

Deal found 12/28

$310

Sat 1/172:00 pmIND - BUF

1 stop6h 29mUnited Airlines

Sun 1/188:30 amBUF - IND

1 stop4h 48mUnited Airlines

Deal found 12/27

$319

Wed 1/217:01 amIND - BUF

1 stop3h 50mAmerican Airlines

Wed 1/215:16 pmBUF - IND

1 stop4h 23mAmerican Airlines

Deal found 12/30

$257

Wed 1/215:35 amIND - BUF

1 stop6h 55mSouthwest

Wed 1/213:45 pmBUF - IND

2 stops6h 20mSouthwest

Deal found 12/30

$314

Tue 1/278:45 amIND - BUF

2 stops8h 20mSouthwest

Tue 2/33:45 pmBUF - IND

1 stop4h 25mSouthwest

Deal found 12/28

$262

Fri 1/302:12 pmIND - BUF

1 stop21h 22mMultiple Airlines

Thu 2/57:59 pmBUF - IND

1 stop13h 44mMultiple Airlines

Deal found 12/30

$198

One-way flights from Indianapolis to Buffalo
Search for one-way flight options from Indianapolis to Buffalo. Find affordable one-way fares based on user searches. Data last updated December 30, 2025.

Sat 1/103:38 pmIND - BUF

1 stop16h 35mFrontier

Deal found 12/28

$153

Thu 4/25:10 amIND - BUF

1 stop6h 39mAmerican Airlines

Deal found 12/28

$179

Sat 1/108:26 pmIND - BUF

2 stops39h 34mMultiple Airlines

Deal found 12/28

$184

Thu 2/1211:25 amIND - BUF

2 stops7h 41mUnited Airlines

Deal found 12/28

$201

Wed 1/712:27 pmIND - BUF

1 stop6h 36mDelta

Deal found 12/28

$307

Wed 1/712:25 pmIND - BUF

2 stops10h 06mUnited Airlines

Deal found 12/29

$312

Thu 4/26:00 amIND - BUF

3 stops30h 42mMultiple Airlines

Deal found 12/28

$343

Find flight deals from Indianapolis to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$257 (American Airlines)
One-way from	$153 (Kiwi.com)
Popular in	February
Cheapest in	May
Average price	$504

Provider with most accurate pricing for Indianapolis-Buffalo flight deals.

Search Deals

Provider most trusted by Cheapflights users for Indianapolis-Buffalo flights.

Search Deals

From Indianapolis to Buffalo

Search Deals

One-way flight from Indianapolis to Buffalo

Search Deals

Highest demand for flights based on searches. 15% potential increase in price ($67 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Indianapolis to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Fri 2/6

10:38 am-6:36 pm

1 stop7h 58m

Buffalo

Sun 2/8

11:02 am-9:43 am

1 stop22h 41m

$185

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Fri 1/30

2:12 pm-11:34 am

1 stop21h 22m

Buffalo

Thu 2/5

7:59 pm-9:43 am

1 stop13h 44m

$198

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Wed 1/21

7:01 am-10:51 am

1 stop3h 50m

Buffalo

Wed 1/21

5:27 pm-10:28 pm

1 stop5h 01m

$257

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Tue 1/27

8:45 am-5:05 pm

2 stops8h 20m

Buffalo

Tue 2/3

3:45 pm-8:10 pm

1 stop4h 25m

$262

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Thu 1/15

6:55 am-6:19 pm

2 stops11h 24m

Buffalo

Sun 1/18

7:14 pm-3:34 pm

1 stop20h 20m

$310

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Wed 1/21

5:35 am-12:30 pm

1 stop6h 55m

Buffalo

Wed 1/21

3:45 pm-10:05 pm

2 stops6h 20m

$314

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Wed 1/14

6:00 am-9:21 am

2 stops27h 21m

Buffalo

Sun 1/18

8:58 pm-11:15 pm

1 stop26h 17m

$318

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Sat 1/17

2:00 pm-8:29 pm

1 stop6h 29m

Buffalo

Sun 1/18

8:30 am-1:18 pm

1 stop4h 48m

$319

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Thu 4/2

5:10 am-11:49 am

1 stop6h 39m

$179

IndianapolisBuffalo

IND - BUF

INDBUF

Indianapolis

Sat 1/10

8:26 pm-12:00 pm

2 stops39h 34m

$184

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/28

Showing 1-10 of 16 results

Compare providers for flights from Indianapolis to Buffalo

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Buffalo in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Indianapolis-Buffalo flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Indianapolis-Buffalo flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Indianapolis-Buffalo flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Indianapolis-Buffalo flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Indianapolis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Buffalo

What is the cheapest month to book a flight from Indianapolis to Buffalo?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to Buffalo (average of $60). Flying from Indianapolis to Buffalo in November is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Buffalo

See what other customers who have flown with Southwest, Delta, and United Airlines from Indianapolis to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

8.0

Very good

4,251 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,014 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

United Airlines

7.4

Good

9,121 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,072 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Frontier

5.7

Fair

3,065 reviews

Southwest

8.0

Very good

4,251 reviews

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

How long is the flight from Indianapolis to Buffalo?
Airlines like American Airlines and Southwest fly from Indianapolis to Buffalo in about 4h 44m. The time it takes to get you to your destination can typically vary by up to 3h 36m. The distance between Indianapolis and Buffalo is about 451 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Indianapolis to Buffalo round-trip?
According to our current data, Frontier ($60), Delta ($83), and American Airlines ($205) offers the cheapest pricing from Indianapolis to Buffalo. Frontier is 84% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Indianapolis to Buffalo one-way?
One-way options have recently been found by users for as low as $87 on American Airlines. Other airlines that offer cheap prices include Southwest from $117 and Delta from $124 one-way.
Can I find deals for flights from Indianapolis to Buffalo that include hotel bookings?
Yes. In addition to deals on Indianapolis to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Indianapolis to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Buffalo.
Can I find deals for business class flights from Indianapolis to Buffalo?
Yes. Cheapflights offers flight deals from Indianapolis to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Indianapolis to Buffalo?
Currently, May is the cheapest month in which you can book a flight from Indianapolis to Buffalo (average of $60). Flying from Indianapolis to Buffalo in November is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Lockport

Cheektowaga

Batavia

Williamsville

Orchard Park

Eden

Amherst

West Seneca

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Indianapolis to Buffalo

O'Hare Intl to John F Kennedy Intl flights

O'Hare Intl to LaGuardia flights

O'Hare Intl to Newark flights

Midway to Newark flights

Midway to John F Kennedy Intl flights

Cincinnati to John F Kennedy Intl flights

Cincinnati to LaGuardia flights

Midway to LaGuardia flights

Cincinnati to Newark flights

Indianapolis to LaGuardia flights

Indianapolis to John F Kennedy Intl flights

Louisville to LaGuardia flights

Indianapolis to Newark flights

Louisville to Newark flights

Louisville to John F Kennedy Intl flights

O'Hare Intl to Buffalo flights

O'Hare Intl to Albany flights

O'Hare Intl to Syracuse flights

O'Hare Intl to Rochester flights

Dayton to John F Kennedy Intl flights

Dayton to LaGuardia flights

O'Hare Intl to White Plains flights

Midway to Buffalo flights

South Bend to John F Kennedy Intl flights

Dayton to Newark flights

South Bend to Newark flights

South Bend to LaGuardia flights

Cincinnati to Albany flights

Midway to Albany flights

Fort Wayne to Newark flights

Kalamazoo to LaGuardia flights

Cincinnati to Stewart flights

Fort Wayne to John F Kennedy Intl flights

Kalamazoo to John F Kennedy Intl flights

Dayton to Albany flights

Indianapolis to Syracuse flights

Kalamazoo to Newark flights

Fort Wayne to LaGuardia flights

Evansville to LaGuardia flights

O'Hare Intl to Islip flights

Midway to White Plains flights

Evansville to Newark flights

Evansville to John F Kennedy Intl flights

Cincinnati to Islip flights

Midway to Rochester flights

South Bend to Albany flights

Midway to Syracuse flights

Indianapolis to Stewart flights

Cincinnati to Syracuse flights

Other flights to Buffalo

Complete your trip

Buffalo car rentals

Buffalo Airport car rentals

Greater Rochester Intl Airport car rentals

Erie Airport car rentals

Niagara Falls Airport car rentals

Bradford Airport car rentals

Jamestown Chautauqua County Airport car rentals

New York car rentals

Rochester car rentals

Albany car rentals

Syracuse car rentals

Islip car rentals

Other flights from Indianapolis

Indianapolis to Orlando flights

Indianapolis to Newark flights

Indianapolis to West Palm Beach flights

Indianapolis to Orlando Sanford Intl flights

Indianapolis to Jacksonville flights

Indianapolis to Fort Lauderdale flights

Top 5 airlines flying from Indianapolis to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$60	Average$208	FlexibilityNo cancel fee	On-time62%
Delta	Cheapest$83	Average$293	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$205	Average$364	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$236	Average$407	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$314	Average$412	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$153+ Cheap flights from Indianapolis to Buffalo (IND - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Indianapolis to Buffalo with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Indianapolis to Buffalo

Cheapest flights from Indianapolis to BuffaloExplore the most affordable flight options available from Indianapolis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Explore the most affordable flight options available from Indianapolis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

Find flight deals from Indianapolis to Buffalo

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Indianapolis to Buffalo that are best for you.

Compare providers for flights from Indianapolis to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Buffalo in December.

Best time to book a flight from Indianapolis to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Indianapolis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Buffalo

What is the cheapest month to book a flight from Indianapolis to Buffalo?

Reviews of airlines servicing Buffalo

See what other customers who have flown with Southwest, Delta, and United Airlines from Indianapolis to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Indianapolis to Buffalo?

What are the cheapest airlines flying from Indianapolis to Buffalo round-trip?

What are the cheapest airlines to fly from Indianapolis to Buffalo one-way?

Can I find deals for flights from Indianapolis to Buffalo that include hotel bookings?

How can I find direct flights from Indianapolis to Buffalo?

Can I find deals for business class flights from Indianapolis to Buffalo?

What is the cheapest month to book a flight from Indianapolis to Buffalo?

Traveling to a place near Buffalo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Indianapolis to Buffalo

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Indianapolis to Buffalo
Explore the most affordable flight options available from Indianapolis to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.