$146+ Cheap flights from Louisville to Buffalo (SDF - BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/5. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — BUF
May 28 — Jun 41
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to Buffalo
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Cheapest flights from Louisville to BuffaloExplore the most affordable flight options available from Louisville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
Explore the most affordable flight options available from Louisville to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:47 pm
SDF
- BUF
1 stop6h 12m
Delta
Sat 6/66:25 am
BUF
- SDF
1 stop3h 34m
Delta
Deal found 4/23![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:06 pm
SDF
- BUF
1 stop23h 58m
Multiple Airlines
Thu 5/2811:36 am
BUF
- SDF
2 stops21h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$295
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am
SDF
- BUF
1 stop5h 40m
Southwest
Fri 8/216:30 am
BUF
- SDF
1 stop7h 05m
Southwest
Deal found 4/23![Southwest logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:06 pm
SDF
- BUF
1 stop23h 58m
Multiple Airlines
Sat 6/67:52 pm
BUF
- SDF
2 stops37h 36m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:36 am
SDF
- BUF
1 stop5h 45m
American Airlines
Mon 5/258:00 am
BUF
- SDF
1 stop6h 16m
American Airlines
Deal found 4/27![American Airlines logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:10 pm
SDF
- BUF
1 stop6h 53m
United Airlines
Wed 6/36:00 am
BUF
- SDF
1 stop6h 21m
United Airlines
Deal found 4/23![United Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/245:59 pm
SDF
- BUF
1 stop5h 33m
Delta
Mon 6/295:12 pm
BUF
- SDF
1 stop7h 20m
Delta
Deal found 4/24![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/204:10 pm
SDF
- BUF
1 stop6h 05m
Southwest
Sun 8/236:20 am
BUF
- SDF
1 stop6h 30m
Southwest
Deal found 4/23![Southwest logo]()
$352
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:40 am
SDF
- BUF
2 stops9h 35m
Southwest
Sat 6/62:40 pm
BUF
- SDF
2 stops8h 40m
Southwest
Deal found 4/23![Southwest logo]()
$362
Best flights from Louisville to BuffaloDiscover carefully curated flight deals from Louisville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
Discover carefully curated flight deals from Louisville to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 28, 2026.
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:05 am
SDF
- BUF
2 stops7h 15m
Southwest
Fri 8/216:30 am
BUF
- SDF
1 stop7h 05m
Southwest
Deal found 4/23![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:10 pm
SDF
- BUF
1 stop6h 53m
United Airlines
Wed 6/36:00 am
BUF
- SDF
1 stop6h 21m
United Airlines
Deal found 4/23![United Airlines logo]()
$326
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2410:35 am
SDF
- BUF
1 stop4h 46m
Delta
Mon 6/2912:04 pm
BUF
- SDF
1 stop4h 42m
Delta
Deal found 4/27![Delta logo]()
$345
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:39 am
SDF
- BUF
1 stop4h 33m
Delta
Sat 6/66:25 am
BUF
- SDF
1 stop3h 34m
Delta
Deal found 4/26![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 am
SDF
- BUF
2 stops6h 00m
Southwest
Sun 8/236:20 am
BUF
- SDF
2 stops7h 50m
Southwest
Deal found 4/23![Southwest logo]()
$405
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:55 pm
SDF
- BUF
1 stop5h 43m
Delta
Mon 7/202:27 pm
BUF
- SDF
1 stop6h 32m
Delta
Deal found 4/23![Delta logo]()
$395
Last-minute flights from Louisville to BuffaloDiscover last-minute flight deals from Louisville to Buffalo. Data last updated April 28, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to Buffalo. Data last updated April 28, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:36 am
SDF
- BUF
1 stop5h 45m
American Airlines
Mon 5/258:00 am
BUF
- SDF
1 stop6h 16m
American Airlines
Deal found 4/27![American Airlines logo]()
$311
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:39 am
SDF
- BUF
1 stop4h 33m
Delta
Sat 6/66:25 am
BUF
- SDF
1 stop3h 34m
Delta
Deal found 4/26![Delta logo]()
$363
This American Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:56 pm
SDF
- BUF
1 stop5h 13m
American Airlines
Sun 5/241:45 pm
BUF
- SDF
1 stop5h 38m
American Airlines
Deal found 4/25![American Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:47 pm
SDF
- BUF
1 stop6h 12m
Delta
Sat 6/66:25 am
BUF
- SDF
1 stop3h 34m
Delta
Deal found 4/23![Delta logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:06 pm
SDF
- BUF
1 stop23h 58m
Multiple Airlines
Thu 5/2811:36 am
BUF
- SDF
2 stops21h 52m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/238:06 pm
SDF
- BUF
1 stop23h 58m
Multiple Airlines
Sat 6/67:52 pm
BUF
- SDF
2 stops37h 36m
Multiple Airlines
Deal found 4/23![Multiple Airlines logo]()
$305
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:38 am
SDF
- BUF
1 stop6h 43m
American Airlines
Sat 5/237:29 pm
BUF
- SDF
1 stop4h 59m
American Airlines
Deal found 4/24![American Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:40 am
SDF
- BUF
2 stops9h 35m
Southwest
Sat 6/62:40 pm
BUF
- SDF
2 stops8h 40m
Southwest
Deal found 4/23![Southwest logo]()
$362
This United Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
SDF
- BUF
1 stop4h 15m
United Airlines
Sun 5/316:03 pm
BUF
- SDF
1 stop5h 46m
United Airlines
Deal found 4/27![United Airlines logo]()
$375
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:10 pm
SDF
- BUF
1 stop6h 53m
United Airlines
Wed 6/36:00 am
BUF
- SDF
1 stop6h 21m
United Airlines
Deal found 4/23![United Airlines logo]()
$326
One-way flights from Louisville to BuffaloSearch for one-way flight options from Louisville to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
Search for one-way flight options from Louisville to Buffalo. Find affordable one-way fares based on user searches. Data last updated April 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/510:33 am
SDF
- BUF
2 stops24h 55m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$146
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/265:30 pm
SDF
- BUF
1 stop6h 02m
Delta
Deal found 4/26![Delta logo]()
$148
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/55:52 pm
SDF
- BUF
1 stop6h 07m
Delta
Deal found 4/26![Delta logo]()
$198
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:35 pm
SDF
- BUF
2 stops8h 35m
Southwest
Deal found 4/25![Southwest logo]()
$203
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:20 am
SDF
- BUF
2 stops9h 00m
Southwest
Deal found 4/26![Southwest logo]()
$208
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:45 am
SDF
- BUF
2 stops6h 00m
Southwest
Deal found 4/25![Southwest logo]()
$265
This United Airlines deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
SDF
- BUF
3 stops16h 31m
United Airlines
Deal found 4/26![United Airlines logo]()
$332
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:10 am
SDF
- BUF
3 stops11h 53m
United Airlines
Deal found 4/25![United Airlines logo]()
$580
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:30 am
SDF
- BUF
3 stops10h 56m
United Airlines
Deal found 4/25![United Airlines logo]()
$1,021
Find flight deals from Louisville to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $293 (Delta) |
One-way from | $146 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $698 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Louisville to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Wed 8/19
7:05 am-2:20 pm
2 stops7h 15m
Buffalo
Fri 8/21
6:30 am-1:35 pm
1 stop7h 05m
$302
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Sat 5/30
2:10 pm-9:03 pm
1 stop6h 53m
Buffalo
Wed 6/3
6:00 am-12:21 pm
1 stop6h 21m
$326
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Wed 6/24
10:35 am-3:21 pm
1 stop4h 46m
Buffalo
Mon 6/29
12:04 pm-4:46 pm
1 stop4h 42m
$345
Quickest round-trip
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Fri 5/22
10:39 am-3:12 pm
1 stop4h 33m
Buffalo
Sat 6/6
6:25 am-9:59 am
1 stop3h 34m
$363
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Thu 7/16
5:55 pm-11:38 pm
1 stop5h 43m
Buffalo
Mon 7/20
2:27 pm-8:59 pm
1 stop6h 32m
$395
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Thu 8/20
6:45 am-12:45 pm
2 stops6h 00m
Buffalo
Sun 8/23
6:20 am-2:10 pm
2 stops7h 50m
$405
Cheapest one-way
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Fri 6/5
10:33 am-11:28 am
2 stops24h 55m
$146
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Fri 6/5
5:52 pm-11:59 pm
1 stop6h 07m
$198
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Fri 7/17
7:11 pm-11:44 pm
1 stop4h 33m
$198
Quickest one-way
LouisvilleBuffalo
SDF - BUF
SDFBUF
Louisville Intl
Mon 9/28
7:30 pm-11:58 pm
1 stop4h 28m
$198
Showing 1-10 of 15 resultsSorted by cheapest first
Compare providers for flights from Louisville to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to Buffalo in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Louisville with our price prediction graph.
SDF-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 28, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Louisville to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Boarding
8.1
Comfort
7.9
Overall
7.9
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentLucy,Nov 2023
ATL - JFK
Related info for your journey
Find useful and relevant information for your journey from Louisville to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Louisville to Buffalo by cabin class
Find flights from Louisville to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Louisville and Buffalo flights
Browse other Louisville and Buffalo flight options. Last updated on April 28, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on April 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Louisville to Buffalo
Discover the top 2 airlines that operate flights from Louisville to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$196 | Average$286 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$239 | Average$387 | FlexibilityNo cancel fee | On-timeN/A |